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Articles (247)

open-access Review Article

Available Online: 01 Oct 2026

Automation in Intracytoplasmic Sperm Injection: Technologies, Outcomes, and Future Directions

Volume 2

Since its introduction in 1992, intracytoplasmic sperm injection (ICSI) has gained significance in assisted reproduction. In certain instances of male infertility, fertilization is made possible by the microsurgical insertion of a single sperm cell straight into the cytoplasm of an oocyte. These days, the majority of in vitro fertilizations worldwide use ICSI, which is carried out manually by qualified embryologists. However, automation is encouraged to increase overall uniformity and efficiency..

Journal: Cell Therapy & Engineering Connect
open-access Research Article

Available Online: 30 Sep 2026

Device-First Continuum AI: Low-Latency, Resilient, and Cost-Efficient Autonomous Operations for the Energy Sector

Volume 3

Journal: Computing&AI Connect
open-access Review Article

Available Online: 30 Sep 2026

Metabolic Reprogramming in Brain Metastases: Integrating Spatial Omics with Non-Spatial Mechanistic Evidence

Volume 3

Brain metastases (BrMs) develop within a metabolically specialized environment, where nutrient availability and interactions with neural, vascular and immune cells can influence tumor growth. Bulk and single-cell studies have identified metabolic alterations, while spatial approaches provide additional information on their regional and cellular context. This mini review examines spatial transcriptomics, proteomics and mass spectrometry imaging alongside biochemical measurements and functional studies, focusing on central carbon metabolism, glutamate-glutamine metabolism, lipid handling..

Journal: GenoMed Connect
open-access Research Article

Available Online: 29 Sep 2026

Integrated Framework for Valuing Urban Wetlands as Flood-Mitigation Infrastructure in Rivers State, Nigeria

Volume 2

Urban wetlands provide key services and support natural hydrological regulation; yet the values and flood-mitigation services they provide could be under-quantified in rapidly urbanizing coastal areas of Africa. Here, Geographic Information System (GIS) flood-risk mapping, spatial hedonic pricing and community perception studies are used to evaluate the capitalized impact of wetland and flood-risk exposure on residential property values within four Local Government Areas of Rivers State, Nigeria (Port Harcourt, Obio-Akpor,..

Journal: Sustainable Processes Connect
open-access Perspective

Available Online: 29 Sep 2026

Long COVID and Cancer Biology: Distinguishing Mechanistic Overlap from Evidence Across Cancer-Related Outcomes

Volume 2

Journal: Cancer Research and Therapy Connect
open-access Review Article

Available Online: 28 Sep 2026

Agrobacterium-mediated genetic transformation studies in soybean (Glycine max (L.) Merrill) for sustainable food and nutritional security: A Review

Volume 2

Journal: Sustainable Food Connect
open-access Perspective

Available Online: 26 Sep 2026

The Circadian–Spliceosome Axis: A Temporal Dimension of Transcriptomic Heterogeneity in Prostate Cancer

Volume 2

Journal: Cancer Research and Therapy Connect
open-access Systematic Review

Available Online: 17 Sep 2026

Clinical Efficacy of Ceftazidime/Avibactam for Treating Infections Caused by Carbapenem-Resistant Klebsiella pneumoniae: A Systematic Review and Meta-Analysis

Volume 2

Journal: Clinical Pharmacy Connect
open-access Research Article

Available Online: 16 Sep 2026

The Crack Clock: A Three-Stage Analytical Framework Predicting When Humidity Will Damage a Panel Painting

Volume 1

Journal: Ecological & Sustainable Materials Connect
open-access Research Article

Available Online: 15 Sep 2026

IncrConsist: Efficient Incremental Consistency Maintenance for LLM-Maintained Knowledge Bases

Volume 3

Journal: Computing&AI Connect
open-access Research Article

Available Online: 08 Sep 2026

Biological Characteristics of Snakeskin Gourami (Trichopodus pectoralis) from Central Kalimantan, Indonesia

Volume 2

Journal: Sustainable Food Connect
open-access Research Article

Available Online: 01 Sep 2026

Sustainable Swine Manure Valorization: Gasification with High-Temperature Steam and CO2 Blend

Volume 2

Journal: Sustainable Processes Connect
open-access Review Article

Available Online: 31 Aug 2026

Noncoding RNA-Mediated Control of HbF Switching: From Molecular Mechanisms to Clinical Translation

Volume 3

Journal: GenoMed Connect
open-access Review Article

Available Online: 31 Aug 2026

The Function of Angiotensin-Converting Enzyme Inhibitors in Chronic Kidney Disease: Pathophysiological Mechanisms and Implications for Practice

Volume 2

Journal: Clinical Pharmacy Connect
open-access Perspective

Available Online: 27 Aug 2026

AI-Guided Self-Driving Laboratories for Advanced Materials Discovery

Volume 3

Journal: Computing&AI Connect
open-access Research Article

Available Online: 26 Aug 2026

Understanding Factors Affecting Participation Rates and Facilitators of Compliance in Breast Screening Program in the UK: A Cross-Sectional Mixed Methods Study

Volume 1

Journal: Evidence Synthesis in Healthcare Connect
open-access Review Article

Available Online: 25 Aug 2026

Pediatric Pure Erythroid Leukemia: Diagnostic Challenges, Immunophenotypic Features, Molecular Pathogenesis, and Practical Diagnostic Approach

Volume 2

Journal: Cancer Research and Therapy Connect
open-access Review Article

Available Online: 20 Aug 2026

Immunotherapy in Glioblastoma: Why Has Progress Been So Difficult?

Volume 2

Journal: Cancer Research and Therapy Connect
open-access Research Article

Available Online: 17 Aug 2026

Machine Learning-Driven Multimodal Forensic Data Fusion for Enhanced Disaster Victim Identification: Integrating DNA, Dental, and Facial Image Data

Volume 3

Journal: Computing&AI Connect
open-access Research Article

Available Online: 15 Aug 2026

Quantification of Bioactive Compounds of Major Medicinal Plants from Bangladesh

Volume 2

Journal: Sustainable Food Connect
open-access Research Article

Available Online: 14 Aug 2026

Comparative Evaluation of Avocado Pear and Moringa oleifera Seeds as Sustainable Bio-Coagulants for Brewery Wastewater Treatment

Volume 1

Journal: Ecological & Sustainable Materials Connect
open-access Research Article

Available Online: 10 Aug 2026

Performance Optimization of High-Speed Wireless Communication Systems Using Machine Learning

Volume 3

Journal: Computing&AI Connect
open-access Research Article

Available Online: 05 Aug 2026

Sustainable Removal of Total Dissolved Solids from Paint Wastewater Using Avocado Pear and Moringa Oleifera Seed Bio-Coagulants Through an Adsorption-Assisted Coagulation–Flocculation Process

Volume 2

Journal: Sustainable Processes Connect
open-access Research Article

Available Online: 04 Aug 2026

Architecture of Sintered-Regolith Lunar Polar Microhabitats for Biofilm Research

Volume 3

Journal: Computing&AI Connect
open-access Case Report

Published: 06 Sep 2026

Reversible Acute Kidney Injury Following Continuous Intravenous Diazepam in Generalized Tetanus: Recovery After Transition to Intravenous Midazolam: A Case Report

Volume 2

Journal: Clinical Pharmacy Connect
open-access Editorial

Published: 24 Aug 2026

Sustainable Strategies to Reduce Food Loss and Waste Across the Supply Chain: A Forward-Looking Perspective

Volume 2

Journal: Sustainable Food Connect
open-access Research Article

Available Online: 02 Aug 2026

Comparative Evaluation of Nutritional and Phytochemical Profiling of Seeds and Leaves of Dennettia tripetala for Pharmacological Applications

Volume 1

Journal: Ecological & Sustainable Materials Connect
open-access Research Article

Published: 01 Sep 2026

Assessment of Multi-Pollutant Concentrations Across Indian Urban Centers: A Case Study Towards Use of Sustainable Materials for Improvement in Air Quality

Volume 1

Journal: Ecological & Sustainable Materials Connect
open-access Research Article

Available Online: 31 Jul 2026

Adsorption of Ciprofloxacin onto Lotus Stem-Derived Biochar: Effects of Solution pH, Temperature, and Coexisting Cations

Volume 2

Journal: Sustainable Processes Connect
open-access Review Article

Available Online: 31 Jul 2026

Mulching Influence on Agricultural Productivity and Climate Change Mitigation

Volume 1

Journal: Ecological & Sustainable Materials Connect
open-access Research Article

Published: 25 Aug 2026

Data-Driven Optimization of Plant-Derived Bio-Coagulants for TDS Removal from Paint Wastewater: Comparative RSM and ANN Modeling

Volume 2

Journal: Sustainable Processes Connect
open-access Research Article

Published: 25 Aug 2026

Molecular Docking and ADME Profiling of N-(Substituted-1,3-benzothiazol-2-yl)benzamide Derivatives as Potential Anticonvulsant Agents

Volume 3

Journal: Molecular Modeling Connect
open-access Research Article

Published: 21 Aug 2026

Long-Term Clinical Outcomes of the Use of Endo-Sealants in the Treatment of Teeth with Destructive Forms of Apical Periodontitis

Volume 3

Radiographic examination remains the primary method used to assess endodontic treatment quality, and the search for objective evaluation methods remains relevant, as standardized criteria would let clinicians evaluate their own work objectively. Objective: To evaluate the effectiveness of treating teeth with periapical pathology based on the state of apical constriction, using clinical and radiographic examination to substantiate the choice of obturation material. Methods: The study involved 156 participants with 194..

Journal: Biomaterials Connect
open-access Research Article

Published: 25 Aug 2026

Revisiting the Prediction of the Partition Coefficient Using Variables Determined by the Conductor-Like Polarizable Continuum Model

Volume 3

Journal: Molecular Modeling Connect
open-access Research Article

Published: 14 Aug 2026

Effect of Incubation Time and Soil Moisture Contents on Lead Speciation in Sewage Sludge Amended Soil

Volume 2

Journal: Sustainable Food Connect
open-access Review Article

Available Online: 14 Jul 2026

Importance of Cell Alignment in Cardiac Tissue Engineering

Volume 3

Native myocardium is a structurally anisotropic, electromechanically integrated tissue in which cardiomyocytes, extracellular matrix fibers, vascular structures, and conduction pathways are organized across multiple length scales. Rather than a simple stack of discrete layers with slight misalignment, its defining architectural feature is a continuous transmural gradient in predominant myofiber angle from the endocardial to the epicardial surface—an organization that underlies anisotropic electrical propagation, regional deformation, ventricular torsion, wall thickening, and..

Journal: Biomaterials Connect
open-access Research Article

Available Online: 14 Jul 2026

Features of Synthesis of a Metal-Matrix Composite Based on Natural Calcium Carbonate

Volume 1

Journal: Ecological & Sustainable Materials Connect
open-access Review Article

Published: 20 Aug 2026

Beyond GDP: A Systematic Scoping Review of New Perspectives on Economic Success in Neoclassical and Ecological Economics in Sub-Saharan Africa

Volume 2

Journal: Sustainable Processes Connect
open-access Review Article

Available Online: 01 Jul 2026

Clinical Effectiveness of Resin Modified Calcium Silicate Cements

Volume 3

This review provides a thorough and critical analysis of the basic properties of resin-modified calcium silicate cements, focusing on issues related to their cytotoxicity and mineralization potential. An important question that remains unresolved in the dental literature. The aim of this review is to examine the available literature on the long-term clinical efficacy of resin-modified calcium silicate cements for direct pulp capping. A literature search was conducted using three electronic..

Journal: Biomaterials Connect
open-access Research Article

Available Online: 01 Jul 2026

Sum Rate Optimization for IRS-Assisted VLC Systems with Time Delay Considerations Using Deep Q-Learning

This article is part of the Special Issue Innovations in Next-Generation Communication and Optical Networks

Volume 3

VVisible light communication (VLC) is a promising solution for high-speed indoor wireless connectivity, offering advantages such as license-free spectrum and enhanced physical-layer security. However, VLC performance is highly dependent on line-of-sight (LoS) conditions and is vulnerable to signal degradation caused by device orientation and dynamic obstructions. To address these challenges, this paper proposes a deep Q-Learning (DQL) framework for resource optimization in intelligent reflecting surface (IRS)-assisted VLC systems. A realistic..

Journal: Communications & Networks Connect
open-access Research Article

Published: 27 Jul 2026

Deconstructing the AI Valuation Paradox: Complementary Assets, Real Options, and Market Sentiment in S&P 500 Firms

Volume 3

Journal: Computing&AI Connect
open-access Research Article

Available Online: 27 Jun 2026

Synthesis, Characterization, Applications and Computational Studies of CA4 Hydrogels Incorporated with ZnO Nanoparticles [CA4-ZnO]

Volume 1

Journal: Ecological & Sustainable Materials Connect
open-access Research Article

Published: 24 Jul 2026

Neural Avatars and Adaptive Systems: Behavioral Dynamics and Ethical Governance in the Metaverse

Volume 3

Journal: Computing&AI Connect
open-access Review Article

Published: 10 Aug 2026

Agro-Blue Commons: Reframing Recreation Through Food–Water–Leisure Integration in the Global South

Volume 2

Journal: Sustainable Food Connect
open-access Research Article

Published: 22 Jul 2026

Chitosan Nanoparticle Delivery of Prunus africana (Hook.f) Kalkman Attenuates TGF-β/SMAD3-Driven Epithelial–Mesenchymal Transition to Suppress Prostate Cancer Metastasis

Volume 2

Journal: Cancer Research and Therapy Connect
open-access Research Article

Published: 15 Jul 2026

A Zero-Trust AI-Blockchain Architecture for Quantum-Secure Metaverse Platforms

Volume 3

Journal: Computing&AI Connect
open-access Review Article

Available Online: 24 Jun 2026

Pharmacological Treatment Approaches in Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS)

Volume 2

Journal: Clinical Pharmacy Connect
open-access Editorial

Published: 16 Jul 2026

Changing Periodontitis Treatment Through the Use of AI, Biomarkers, and Regenerative Technology

Volume 1

Recent advances in digital technologies are transforming the diagnosis and management of periodontal diseases by enabling more precise, efficient, and patient-centered care. This editorial provides an overview of selected emerging technologies and their applications in periodontology, with particular emphasis on artificial intelligence (AI) based tools. These innovations include AI-assisted radiographic analysis, the integration of salivary biomarkers into point-of-care testing, and advances in regenerative periodontal therapies. Collectively, these approaches facilitate more..

Journal: Digital Dentistry Connect
open-access Review Article

Published: 13 Jul 2026

Nanoparticle-Based Vaccines: From Design and Immune Modulation to Clinical Translation

Volume 1

Journal: Pharmaceuticals and Nanotech Connect
open-access Review Article

Published: 09 Jul 2026

Unveiling the Fourth Meningeal Layer: Implications for Brain Structure, Function, and Neurological Disease

Volume 3

Journal: GenoMed Connect
open-access Research Article

Published: 08 Jul 2026

Impact of Polishing on Physicochemical Properties, Cooking Behavior, and Anthocyanin Content in Njavara Red Rice

Volume 2

Journal: Sustainable Food Connect
open-access Review Article

Published: 08 Jul 2026

Dynamic Virtual Tumor Cells Powered by Spatial Omics for Translational Oncology

Volume 3

Journal: GenoMed Connect
open-access Review Article

Published: 26 Jun 2026

Tumor Suppressor Gene Loss and Immune-Epigenetic Reprogramming

This article is part of the Special Issue Epigenetic Regulation of Tumor Immunity

Volume 2

Journal: Cancer Research and Therapy Connect
open-access Review Article

Published: 02 Jul 2026

Targeting Angiogenesis in Rheumatoid Arthritis: Mechanistic Insights, Therapeutic Advances and Nanomedicine Perspectives

Volume 1

Angiogenesis is the formation of new blood vessels, a physiological process that can become dysregulated under pathological conditions, including autoimmune diseases. In rheumatoid arthritis, a prototypic autoimmune disorder characterized by chronic synovial inflammation and joint destruction, pathological angiogenesis plays a crucial role in sustaining inflammation, facilitating immune cell infiltration, and promoting pannus formation. This review synthesizes recent advances (2023–2025) in the understanding of the mechanisms driving angiogenesis in autoimmune diseases,..

Journal: Pharmaceuticals and Nanotech Connect
open-access Research Article

Published: 06 Jul 2026

In Silico Evaluation of Microbial Chitinase for Its Anticancer Potential Against Abnormal Glycosylation

Volume 3

Journal: Molecular Modeling Connect
open-access Review Article

Published: 12 Jun 2026

Spatial Profiling of the Head and Neck Squamous Cell Carcinoma Microenvironment: Reshaping Our Understanding and Therapeutic Opportunities

Volume 3

Head and neck squamous cell carcinoma (HNSCC) is characterized by a highly heterogeneous tumor microenvironment (TME), which plays a critical role in disease progression and therapeutic resistance. The emergence of spatial omics and multimodal imaging approaches, including spatial transcriptomics, proteomics and metabolomics, has revolutionized the understanding of the tumor microenvironment (TME) by preserving the spatial architecture of molecular landscapes. This review synthesizes key advances enabled by spatial omics in the..

Journal: GenoMed Connect
open-access Research Article

Published: 22 Jun 2026

Gold Nanoparticle Shape Design for Ophthalmic Imaging and Therapy

Volume 1

Journal: Pharmaceuticals and Nanotech Connect
open-access Mini-Review

Published: 11 Jun 2026

Regional Differences in Brain Tumors: Genetic Drivers and Spatial Molecular Ecology

Volume 3

The human brain exhibits marked regional specialization in cellular composition, gene expression, and tissue architecture. Growing evidence suggests that these spatial differences influence both the anatomical distribution of brain tumors and their subsequent progression. Across tumor types such as gliomas, meningiomas, and brain metastases, specific molecular subtypes frequently show characteristic anatomical distributions, suggesting a functional coupling between tumor genetics and regional brain microenvironments. In this mini review, we summarize recent..

Journal: GenoMed Connect
open-access Review Article

Published: 22 Jun 2026

Life Cycle Assessment (LCA) For Prosthetic and Orthotic Materials in the Health Care Sector

Volume 1

Life Cycle Assessment (LCA) has become a comprehensive analytical framework for quantifying the environmental performance of medical devices throughout their entire life cycles. This review integrates methodological fundamentals, database selection guidelines, and impact assessment approaches relevant to healthcare applications, with a particular focus on prosthetic and orthotic technologies. By integrating ISO-compliant modeling practices, robust inventory datasets such as ELCD 3.2 and ecoinvent, and modern impact assessment methods such as ReCiPe..

Journal: Ecological & Sustainable Materials Connect
open-access Research Article

Published: 04 Jun 2026

Nutritional, Antioxidant and Sensory Properties of Wheat–Oat Composite Sourdough Breads

Volume 2

Journal: Sustainable Food Connect
open-access Research Article

Published: 03 Jun 2026

Age and Charge Effects in Cortical Bone: Raman Study of Phosphate Ions Stretching

Volume 3

A quantitative assessment of internal electrostatic fields in bone tissue was conducted within the framework of the “bone-battery” concept. The influence of these fields on atomic structure and dynamics may have been significantly underestimated. To test this hypothesis, Raman spectroscopy was applied to cortical bone samples from young and mature rats. Particular attention was given to the v1(PO43−) band at 960 cm−1 in the Raman spectra to investigate the coupling..

Journal: Biomaterials Connect
open-access Short Communication

Published: 25 May 2026

Y-STR Mutation Patterns in North Indian Male Relatives at 16 Loci: A Preliminary Study

Volume 3

Journal: GenoMed Connect
open-access Research Article

Published: 26 May 2026

Performance Characterization of gr-owc, the GNU Radio Out-of-Tree Module for Optical Wireless Communications

This article is part of the Special Issue Innovations in Next-Generation Communication and Optical Networks

Volume 3

As researchers continue to investigate novel technologies for next-generations of wireless communications systems, flexible and adaptable tools remain essential for system testing and development. Software-Defined Radios (SDRs) provide flexible and reconfigurable signal-processing capabilities, thereby serving as a crucial platform for the rapid prototyping, testing, and experimental validation of communication systems. GNU Radio is an open-source SDR toolkit that enables the extension of its core software library through the development of..

Journal: Communications & Networks Connect
open-access Commentary

Published: 26 May 2026

The Mirage of Miracle Cures: Hydroxychloroquine and Ivermectin in COVID-19

Volume 1

The global coronavirus disease 2019 (COVID-19) pandemic created unprecedented urgency for effective therapeutic interventions. During the early phase of the pandemic, when specific antivirals and vaccines were unavailable, hydroxychloroquine (HCQ) and ivermectin (IVM) emerged as widely promoted therapeutic candidates due to their reported in vitro antiviral activity, proposed mechanisms of action, and anecdotal clinical observations. Both drugs were rapidly incorporated into clinical practice and national treatment policies despite substantial pharmacological..

Journal: Evidence Synthesis in Healthcare Connect
open-access Review Article

Published: 05 Jun 2026

Spatial Heterogeneity of TMEs in cHL and PDAC: Mechanistic Insights and Therapeutic Perspectives

Volume 3

The tumor microenvironment (TME) is a critical niche that influences tumor progression and the development of therapeutic resistance. Spatial omics technologies enable in situ investigation of cellular ecology and intercellular interactions within the TME, addressing the lack of spatial context associated with bulk and single-cell sequencing approaches. Classical Hodgkin lymphoma (cHL) and pancreatic ductal adenocarcinoma (PDAC) exhibit distinct TME characteristics: cHL is characterized by dense immune-cell infiltration accompanied by functionally..

Journal: GenoMed Connect
open-access Research Article

Published: 21 May 2026

Computational Identification of GPCR-Targeting Bioactive Compounds from Ageratum conyzoides for Anti-Aging

Volume 3

Journal: Molecular Modeling Connect
open-access Perspective

Published: 21 May 2026

From Spoilage to Sustainability: A Prescriptive Framework for AI-Enabled Remaining Shelf-Life Prediction

Volume 2

Journal: Sustainable Food Connect
open-access Perspective

Published: 22 May 2026

Chrono-Adaptive Resistance Disruption (CARD): A Novel Pharmacological Framework to Address Anticancer Drug Resistance

Volume 2

Drug resistance in anticancer therapy has long been a major challenge in oncology, biomedical, and pharmacological research. Despite numerous efforts targeting molecular and pathway-level mechanisms and evaluating combination therapies, current pharmacological approaches remain largely stagnant and show limited consideration of circadian variations in tumor biology and drug resistance. Growing preclinical and clinical evidence suggests that circadian rhythms fundamentally regulate drug metabolism, cellular stress, DNA repair, and adaptive resistance mechanisms. This..

Journal: Cancer Research and Therapy Connect
open-access Research Article

Published: 21 May 2026

A Comparison of Hot Dry and Transitional Season Solar Drying with A Modified V-Corrugated Solar Air Heater

Volume 2

Journal: Sustainable Processes Connect
open-access Review Article

Published: 20 May 2026

Digital Twin Applications in Biomaterials Science: Toward Predictive Design and Personalized Healthcare

Volume 3

Journal: Biomaterials Connect
open-access Research Article

Published: 22 Jun 2026

Computational Exploration of Mutant SARS-CoV-2 Main Protease as a Target for Binding and Inhibition Attributes Utilizing Antiviral Drugs for Therapeutic Application

Volume 3

Journal: Molecular Modeling Connect
open-access Review Article

Published: 13 May 2026

Synthetic Polymer Based Nano Drug Delivery Systems for Precise Alzheimer’s Disease Therapy

Volume 2

Journal: Cell Therapy & Engineering Connect
open-access Research Article

Published: 08 Jun 2026

Thermodynamic Quantification of Multi-Sequence DNA Recognition by Prokaryotic Transcription Factor: A Molecular Dynamics Simulation Study

Volume 3

Journal: Molecular Modeling Connect
open-access Systematic Review

Published: 20 May 2026

Mpox Clinical and Epidemiological Patterns in the Central African Republic: A Systematic Review and Meta-Analysis

Volume 1

This study incorporated 12 years of evidence (2010–2022) on Mpox epidemiology, vaccination, and clinical patterns in the Central African Republic (CAR), providing insights to inform targeted control strategies for this re-emerging threat. This systematic review and meta-analysis were conducted in accordance with PRISMA guidelines. Literature searches were performed using PubMed, Scopus, ScienceDirect, Web of Science, Embase, the Cochrane Library, and AJOL. A random-effects model was used to pool estimates in..

Journal: Evidence Synthesis in Healthcare Connect
open-access Research Article

Published: 11 May 2026

Attention-Based LSTM for Sign Language Recognition Leveraging Spatiotemporal Keypoints

Volume 3

Journal: Computing&AI Connect
open-access Research Article

Published: 12 May 2026

A Comparative Evaluation of Imputation Techniques for Missing Data: A Simulation-Based Analysis

Volume 3

Missing data are a common occurrence in research and, if not appropriately addressed prior to analysis, may compromise the validity of study findings. This article evaluates the effectiveness of various imputation techniques as formal approaches for handling missing covariate data. Root Mean Squared Error (RMSE) was computed for each imputation method under Missing Completely at Random (MCAR) and Missing at Random (MAR) mechanisms to identify the technique that yielded the..

Journal: Computing&AI Connect
open-access Research Article

Published: 09 May 2026

Computational Investigation of Selected Antivirals and mAbs Targeting the RBD of Omicron to Get Insights into Structure and Binding Attributes

Volume 3

Journal: Molecular Modeling Connect
open-access Review Article

Published: 08 May 2026

AI-Enabled Generative Design of Immune Cells and Receptors for Programmable Immunity

Volume 2

Recent advances in generative artificial intelligence have begun to reshape the field of cell and immune engineering. By learning the statistical and structural principles underlying biological systems, generative models can now design T-cell receptors, chimeric antigen receptors, and synthetic immune circuits that satisfy complex requirements for affinity, stability, and specificity. When integrated into automated design–build–test–learn pipelines, these models facilitate iterative cycles of hypothesis generation, experimental validation, and model refinement, thereby..

Journal: Cell Therapy & Engineering Connect
open-access Research Article

Published: 21 May 2026

Green Sustainable Synthesis of Silver Nanoparticles from Extracts of Garden Spearmint Mentha spicata for Antibiotic and Antioxidant Activities

Volume 2

Journal: Sustainable Processes Connect
open-access Review Article

Published: 11 May 2026

Plant-Mediated Green Synthesis of Nanomaterials for Sustainable Energy Applications

Volume 2

Journal: Sustainable Processes Connect
open-access Perspective

Published: 06 May 2026

Rethinking “Enough”: From Food Security to Nutrition-Driven Sustainable Food Systems

Volume 2

Journal: Sustainable Food Connect
open-access Research Article

Published: 02 Apr 2026

Temporal DNA-Based Key Derivation and Metadata Fingerprinting for Secure On-Device Digital Forensics in IoT Systems

Volume 3

Journal: Computing&AI Connect
open-access Research Article

Published: 23 Apr 2026

Innovative Sustainable Processes in the Food and Beverage Sector: Driving Consumer Preferences and Building Brand Loyalty

Volume 2

Journal: Sustainable Processes Connect
open-access Research Article

Published: 20 May 2026

Morphological Studies of the Efficiency of Using Modern Endohermetics in the Treatment of Teeth with Destructive Periodontitis and Destroyed Apical Constriction

Volume 3

Journal: Biomaterials Connect
open-access Research Article

Published: 31 Mar 2026

Electronic, Structural and Molecular Implications of Curcumin and Its Relationship with Apoptosis in A549 Cells

Volume 3

Journal: Molecular Modeling Connect
open-access Review Article

Published: 10 Apr 2026

Pomegranate Peel Extract as a Natural Antimicrobial Agent: Extraction Methods, Biochemical Composition, Mechanism of Action, and Application in Food Packaging

Volume 2

Journal: Sustainable Food Connect
open-access Systematic Review

Published: 18 Mar 2026

Mpox and Varicella-Zoster Virus Coinfection in the Democratic Republic of Congo: A Systematic Review and Meta-Analysis

Volume 1

Introduction: Monkeypox (Mpox) is an endemic disease in the Democratic Republic of Congo (DRC). Despite five decades of outbreaks, gaps persist in understanding the clinical patterns of Mpox and its coinfections with varicella-zoster virus (VZV) and human immunodeficiency virus (HIV) in this high-burden setting. This systematic review and meta-analysis were conducted to synthesize data on the clinical presentation of Mpox and coinfection trends in the Democratic Republic of the Congo...

Journal: Evidence Synthesis in Healthcare Connect
open-access Research Article

Published: 26 Mar 2026

Association of 12q21.32 cn-LOH Affecting the KITLG p53 Response Element with Therapy Resistance in Acute Leukemia

Volume 2

Journal: Cancer Research and Therapy Connect
open-access Research Article

Published: 25 Mar 2026

Descriptive Analysis of Valsartan-Related Adverse Events Reported in the FAERS Database

Volume 2

Journal: Clinical Pharmacy Connect
open-access Review Article

Published: 31 Mar 2026

Here, There, and Everywhere: Alpha-Fetoprotein in Cancer Immunotherapy

Volume 2

Alpha-fetoprotein (AFP) delivers nutrients to immature cells in a shuttle-like manner via alpha-fetoprotein receptor (AFPR)-mediated endocytosis. A small subset of immature myeloid-derived suppressor cells (MDSCs) acts as a key regulator of immune tolerance during pregnancy, cancer, and other conditions. MDSCs, low doses of AFP, and AFP-binding ligands can modulate both the innate and adaptive immune responses. MDSCs decrease excessive immune activation, while their depletion can reverse immune suppression. Reduction of..

Journal: Cancer Research and Therapy Connect
open-access Perspective

Published: 26 Mar 2026

Fine-Tuning vs. RAG: A Position Paper from the Perspective of LLM-Based Cybersecurity Modeling

Volume 3

Large Language Models (LLMs) have revolutionized natural language processing (NLP) tasks, enabling critical capabilities across domains such as business, finance, and cybersecurity analysis. In particular, LLMs are becoming increasingly important in cybersecurity by supporting threat and vulnerability analysis, intelligent response generation, pattern recognition, and automated threat detection. Although LLMs are pre-trained with a large amount of knowledge, their application to specific domains, such as cybersecurity, is often limited by insufficient..

Journal: Computing&AI Connect
open-access Research Article

Published: 29 Jan 2026

Microbial Utilization of Ramie Gum: A Potential Avenue for Biotechnological Applications

Volume 2

Journal: Sustainable Processes Connect
open-access Editorial

Published: 31 Dec 2025

Preface

Volume 2

Volume 2 of Computing&AI Connect (CAIC) presents 21 high-quality, peer-reviewed research articles that reflect CAIC’s commitment to advancing the theory, design, and application of computing and artificial intelligence–driven systems. Volume 2 articles cover contemporary challenges in intelligent systems, communication networks, security, data analytics, and human-centered technologies. They also contribute to the development of foundational methodologies and interdisciplinary perspectives. A central focus of this volume is the pervasive role of artificial..

Journal: Computing&AI Connect
open-access Research Article

Published: 16 Jan 2026

Characterizing Immunodeficiencies Using Entropy Phase Transitions as Signatures of the Status of the Immune System

Volume 2

Journal: Cell Therapy & Engineering Connect
open-access Review Article

Published: 29 Dec 2025

Smart Textiles: An Interdisciplinary Overview of Advances, Applications, and Future Prospects

Volume 2

Journal: Biomaterials Connect
open-access Editorial

Published: 30 Dec 2025

Preface

Volume 2

We are pleased to present the second volume of Communications & Networks Connect, a multidisciplinary journal dedicated to advancing research in communication and networking technologies across the electromagnetic spectrum. This volume aligns with the journal's mission to provide a platform for innovative research focusing on the challenges posed by heterogeneous networks, energy efficiency, and robust security measures. The research articles featured in this volume underscore the importance of connecting theoretical..

Journal: Communications & Networks Connect
open-access Research Article

Published: 29 Dec 2025

Sustainable Modeling of the Urban Air Quality in Abu Dhabi Using Machine Learning and Open-Source Satellite Data

Volume 1

This study develops a predictive AI model to monitor and forecast air quality in Abu Dhabi using publicly available satellite-based environmental datasets. The study uses datasets from NASA’s MODIS, Copernicus Atmosphere Monitoring Service (CAMS), and OpenAQ, alongside meteorological data from the UAE’s National Center of Meteorology. Supervised learning techniques, including Random Forest and LSTM neural networks, are applied to analyze trends in PM2.5, PM10, NO2, and CO concentrations in relation..

Journal: Sustainable Processes Connect
open-access Research Article

Published: 16 Jan 2026

Medication Non-Adherence Behaviors and Potential Barriers Among Chronically Ill Patients

Volume 2

Journal: Clinical Pharmacy Connect
open-access Editorial

Published: 29 Dec 2025

Preface

Volume 2

With the completion of Volume 2, Molecular Modeling Connect proudly marks its second year of contributions to the scientific community, representing another significant step forward in its mission to serve as a dynamic forum for the global molecular modeling community. This volume stands as a testament to the growing relevance of computational and theoretical approaches in shaping modern molecular science and to the enthusiasm of researchers who are advancing this..

Journal: Molecular Modeling Connect
open-access Review Article

Published: 30 Dec 2025

Spatial Omics in Decoding Oral Squamous Cell Carcinoma Heterogeneity: Microenvironment Crosstalk and Multi-Omics Integration

Volume 2

Oral squamous cell carcinoma (OSCC) is a significant concern within head and neck cancers due to its high heterogeneity, which contributes to poor treatment outcomes and low survival rates in advanced stages. This review discusses how spatial omics methods are used to explore tumor heterogeneity in OSCC. It focuses on alterations in the cellular, molecular, and immune microenvironment, which are driven by cancer stem cells, stromal interactions, genetic instability, epigenetic..

Journal: GenoMed Connect
open-access Mini-Review

Published: 31 Dec 2025

Covalent BH3-Mimetics and PROTACs: Targeting BCL2 Family for Precision Apoptosis Induction

Volume 1

The BCL2 family of proteins serves as a central regulator of mitochondrial outer membrane permeabilization (MOMP) and intrinsic apoptosis, with anti-apoptotic members such as BCL2, BCL-XL, and MCL1 frequently overexpressed in many cancers to evade programmed cell death. Traditional BH3 mimetics, such as venetoclax and navitoclax, have revolutionized the treatment of hematologic malignancies by competitively inhibiting these pro-survival proteins. Yet, they face challenges, including acquired resistance, on-target toxicities, and limited..

Journal: Cancer Research and Therapy Connect
open-access Review Article

Published: 29 Dec 2025

A Century of Alkaptonuria: Evolving Insights into a Rare Metabolic Disorder

Volume 2

Journal: GenoMed Connect
open-access Research Article

Published: 27 Dec 2025

Effect of Conjugated siRNA-Gold Nanoparticles on Antibiotic-Resistance Integron Class I Gene

Volume 2

Journal: GenoMed Connect
open-access Research Article

Published: 30 Dec 2025

Sheaf Cohomology for Fragment-Sequencing in Hierarchical Block Rectangular Matrices with Spectral Gaps in the Presence of Random Effects and White Noise: The Chain

Volume 2

The sheaf cohomology of topological shift for the block-rectangular matrix-representation of the hierarchical Markov Model incorporates an analytic formulation of white noise and of random effects. New analytical techniques for fragment sequencing are developed. The fragment sequencing is obtained after the topological Markov chain of the adjacency matrix of the corresponding undirected graph; the presence of white noise and that of random effects are included. The paradigm consists in defining..

Journal: Computing&AI Connect
open-access Research Article

Published: 30 Dec 2025

Enhancing Fiber Yield and Environmental Sustainability Through Integrated Fertilization Strategies and Waste Valorization of Ramie (Boehmeria nivea L.)

Volume 1

Journal: Sustainable Processes Connect
open-access Review Article

Published: 31 Dec 2025

Approaches for Dental Gypsum Modifications: A Narrative Review

Volume 2

Journal: Biomaterials Connect
open-access Research Article

Published: 20 Dec 2025

The Human Intelligence linguistic Variable Is a Potential Fuzzy Computational Model for the Natural Language Expression Human Intelligence

Volume 2

This paper presents a fuzzy, computational model for the natural-language term ‘human intelligence’. This mathematical model accounts for multiple interpretations of the term ‘intelligent’ and enables comparison of these interpretations for a given IQ score. The model is a linguistic variable–based mathematical framework specifically designed to represent human intelligence. The model is constructed systematically throughout the paper. First, the term ‘human intelligence’ is represented as a fuzzy set. This step..

Journal: Computing&AI Connect
open-access Review Article

Published: 29 Dec 2025

Computing and AI in Genomics-Driven Precision Oncology: Methods, Trials, and Translation

Volume 2

Journal: Computing&AI Connect
open-access Review Article

Published: 25 Dec 2025

Water Footprint and Water Resources Sustainability: A Review

Volume 1

Journal: Sustainable Processes Connect
open-access Research Article

Published: 19 Dec 2025

Enhancing Pest Management in Precision Agriculture: Integration of Improved YOLOv5 and IoT Technology for Efficient Codling Moth Detection

Volume 2

Journal: Computing&AI Connect
open-access Review Article

Published: 25 Dec 2025

Hydrogel-Based Biosensors in Biomedical Applications

Volume 2

Hydrogels have significant potential for various applications due to their high water content and unique three-dimensional interconnected structure. Due to their excellent biocompatibility, tunable dynamic characteristics, and sensitive responses to environmental stimuli, including temperature, pH, and ions, hydrogels are an ideal material platform for new biosensors. While synthetic hydrogels allow precise control over structure and function through chemical or physical methods to meet the requirements of various applications, natural hydrogels..

Journal: Biomaterials Connect
open-access Research Article

Published: 18 Dec 2025

AI-Driven Machine Learning Analysis in Major Depressive Disorder (MDD): Sex-Based Variations in Oxytocin and Clinical Profiles

Volume 2

Journal: GenoMed Connect
open-access Research Article

Published: 18 Dec 2025

Data Delivery for Standardizing Sustainable Whole-Building Lifecycle Assessment Using the Proposed OpenBIM Framework

Volume 1

Journal: Sustainable Processes Connect
open-access Review Article

Published: 31 Dec 2025

Origin, Evolution, and Regulation of Cancer Genes: An Overview

Volume 2

Cancer is characterized by abnormal cell proliferation in multicellular organisms. Its emergence is linked to the evolution of multicellularity billions of years ago. The “incipient cancer genes” (proto-oncogenes) presumably evolved from genes involved in cell reproduction during the evolutionary transition from unicellular to multicellular organisms. Although these incipient cancer genes initially promoted rapid cell division required for growth at specific developmental stages, their activity had to be tightly regulated to..

Journal: GenoMed Connect
open-access Research Article

Published: 08 Dec 2025

Security Assurance for 5G Split gNB and AMF Vulnerabilities

Volume 2

Journal: Computing&AI Connect
open-access Research Article

Published: 04 Dec 2025

Risk Assessment of Heavy Metal Contamination in Soil for Sustainable Environmental Management in Urban and Rural Areas of Gujrat District, Pakistan

Volume 1

Journal: Sustainable Processes Connect
open-access Research Article

Published: 08 Dec 2025

A Unified Snort–OSSEC Hybrid Intrusion Detection Framework for Cloud Security

Volume 2

Journal: Communications & Networks Connect
open-access Systematic Review

Published: 01 Dec 2025

Efficacy of Monoclonal Antibodies for Malaria Prevention: A Meta-Analysis

Volume 1

Journal: Clinical Pharmacy Connect
open-access Research Article

Published: 16 Dec 2025

Computational Simulations-Optimization of UHMWPE Knee Arthroplasty Linear Abrasive Wear

Volume 2

Journal: Biomaterials Connect
open-access Research Article

Published: 25 Nov 2025

6G Communication Systems Utilizing Intelligent Reflective Surfaces for Improved Data Rates Based on AI

This article is part of the Special Issue Artificial Intelligence Advances in Computing Networks and Systems

Volume 2

Intelligent Reflecting Surfaces (IRSs) are essential for energy-efficient 6G networks; however, enhancing their performance to attain both elevated data rates and energy efficiency continues to be a formidable challenge. This paper uses artificial intelligence (AI) to solve this problem by creating a new AI-based optimization algorithm called Dynamic and Static Particle Swarm Optimization (DS-PSO). The suggested AI method intelligently learns the best phase-shift settings for IRS elements, balancing exploration and..

Journal: Computing&AI Connect
open-access Review Article

Published: 06 Nov 2025

Sustainable Degradation of Organic Pollutants Using Various Treatment Processes: A Review

Volume 1

Journal: Sustainable Processes Connect
open-access Review Article

Published: 28 Nov 2025

Novel Nano-Technologies to Enhance Drug Solubility, Dissolution and Bioavailability of Poorly Water-Soluble Drugs

Volume 2

Journal: Biomaterials Connect
open-access Research Article

Published: 27 Oct 2025

High-Purity Production of Endothelial Cells from Human Pluripotent Stem Cells

Volume 1

Journal: Cell Therapy & Engineering Connect
open-access Research Article

Published: 30 Oct 2025

Unraveling Conformational Thermodynamics of Ligand Binding to Fluoride Riboswitch Aptamer: Implications for Therapeutic Design

Volume 2

Journal: Molecular Modeling Connect
open-access Research Article

Published: 24 Oct 2025

The Application of IoT Technology in Social Work: Innovative Models for Home Care of the Elderly

Volume 2

Journal: Computing&AI Connect
open-access Research Article

Published: 22 Oct 2025

Challenges and Opportunities in Solid Waste Management for Sustainability in District Hyderabad, Pakistan

Volume 1

Journal: Sustainable Processes Connect
open-access Research Article

Published: 31 Oct 2025

Exploring Neuromarketing Techniques for Advancing Sustainability in India’s Food and Agribusiness Sector

Volume 1

Despite growing global interest, neuromarketing remains underutilized within India’s agri-food sector. This study examines the awareness, application, and potential of neuromarketing tools, including EEG (electroencephalography), eye-tracking, the Implicit Association Test (IAT), and virtual or augmented reality (VR/AR), in influencing sustainable consumer behavior in India. Respondents were selected using purposive and snowball sampling techniques, ensuring a diverse representation of stakeholders. While global corporations leverage neuroscience to refine marketing strategies, Indian agribusinesses..

Journal: Sustainable Food Connect
open-access Systematic Review

Published: 21 Oct 2025

Prevalence of Helicobacter pylori Infection in India: A Systematic Review and Meta-Analysis

Volume 1

This study estimated the prevalence of H. pylori infection in India among adults and children with and without gastrointestinal (GI) disorders. This meta-analysis was conducted in accordance with the 2020 PRISMA guidelines and registered with PROSPERO (CRD42024597401). Scientific databases (e.g., MEDLINE, CINAHL, and Google Scholar) were searched to identify English-language articles from India presenting data on H. pylori prevalence. The quality of the included studies was assessed, and prevalence estimates..

Journal: Evidence Synthesis in Healthcare Connect
open-access Research Article

Published: 04 Oct 2025

Optimizing Cluster Head Selection and Routing in 5G WSNs: A Reinforcement Learning and Deep Learning Approach

Volume 2

Journal: Communications & Networks Connect
open-access Research Article

Published: 30 Oct 2025

On the Added Value Conception for the Implementation Instruments Towards Sustainability of the Markets with Carbon Risk

Volume 1

Journal: Sustainable Processes Connect
open-access Editorial

Published: 03 Oct 2025

Current Insights into Pharmacogenomics of Noncoding RNAs for Cancer Therapy

Volume 2

Cancer remains a significant global health challenge, with varying incidence and mortality rates across the globe. According to the Surveillance, Epidemiology, and End Results (SEER) registry [1] and the American Cancer Society (ACS) [2], more than 2 million new cancer cases are expected in the US by 2025. Understanding the burden of disease and advancements in tailored treatments, also known as precision or personalized medicine, is crucial for improving patient..

Journal: GenoMed Connect
open-access Review Article

Published: 28 Sep 2025

The Role of Pharmacists in Public Health and Disease Prevention: What Do We Know?

Volume 1

Background: Non-communicable diseases and persistent infectious threats continue to cause substantial premature mortality. Over 85% of the global population lives within walking distance of a pharmacy, positioning pharmacists as highly accessible primary-health providers. Aims: To review evidence on pharmacists’ public-health activities, propose a four-domain service framework, and identify barriers limiting scale-up, particularly in low- and middle-income settings. Methods: A conventional narrative review was conducted. Targeted manual searches of PubMed, Scopus,..

Journal: Clinical Pharmacy Connect
open-access Research Article

Published: 23 Sep 2025

Drying Kinetics and Thermodynamic Properties of Cassava (Manihot esculenta Crantz) Peel as a Sustainable Agro-Industrial By-Product

Volume 1

Journal: Sustainable Processes Connect
open-access Research Article

Published: 19 Sep 2025

Rewiring Education for a Super-Smart Society: Cognitive Integrity, AI Ethics, and the Future of Knowledge

Volume 2

Journal: Computing&AI Connect
open-access Editorial

Published: 16 Sep 2025

Revolutionizing Cardio-Oncology: Utilizing Artificial Intelligence to Build a Cutting-Edge Cancer Registry in Pakistan

Volume 2

Cardio-oncology is a specialized field focused on delivering effective cancer therapies while minimizing cardiotoxicity. It also involves strategies for the timely identification and appropriate management of cardiovascular complications arising from cancer treatment. Cancer patients have the highest mortality from cardiovascular disease, underscoring the critical importance of the field of cardio-oncology. Currently, data on the outcomes of specialized cardio-oncology services are limited, highlighting a pressing need to establish a comprehensive and..

Journal: Computing&AI Connect
open-access Review Article

Published: 12 Sep 2025

Organic Compounds Removal Using Magnetic Biochar from Textile Industries Based Wastewater-A Comprehensive Review

Volume 1

Journal: Sustainable Processes Connect
open-access Review Article

Published: 05 Sep 2025

Embracing Sustainable Processes in the Pharmaceutical Industry with Green Chemistry and Engineering

Volume 1

Journal: Sustainable Processes Connect
open-access Review Article

Published: 05 Oct 2025

Secure and Privacy-Preserving Data Management in Train Coupling/Decoupling Scenarios: A Comprehensive Review and Future Perspectives

Volume 2

Journal: Computing&AI Connect
open-access Review Article

Published: 23 Oct 2025

Integration of Nanotechnology and Nanomaterials in Biomaterials Research

Volume 2

Journal: Biomaterials Connect
open-access Review Article

Published: 02 Sep 2025

Sustainable Approaches Towards Nanomaterial Synthesis: Strategies, Properties, and Process Integration

Volume 1

Journal: Sustainable Processes Connect
open-access Research Article

Published: 22 Sep 2025

Sustainable Valorization of Amazonian Pracaxi (Pentaclethra macroloba (Willd.)) Residues via Optimized Ultrasound-Assisted Extraction of Bioactive Compounds

Volume 1

Journal: Sustainable Processes Connect
open-access Research Article

Published: 11 Oct 2025

Enhanced Biomass and Photosynthetic Pigment Productivity of Spirulina platensis Using a Sustainable Medium from Chicken Feather and Moringa oleifera Leaf Extract

Volume 1

Journal: Sustainable Processes Connect
open-access Review Article

Published: 20 Sep 2025

Microbial Bioremediation Strategies for Sustainable Wastewater Treatment

Volume 1

Journal: Sustainable Processes Connect
open-access Research Article

Published: 01 Sep 2025

Integrating Rivest–Shamir–Adleman (RSA) Encryption and Forward Error Correction (FEC) Codes for Secure and Robust Underwater Optical Wireless Communication

Volume 2

Journal: Communications & Networks Connect
open-access Research Article

Published: 08 Aug 2025

An Enhanced Puma Optimized Reinforcement Learning Model for Detection of Results Anomalies in Higher Education

Volume 2

Journal: Computing&AI Connect
open-access Research Article

Published: 05 Aug 2025

Effective Decolorization of Direct Blue-1 Dye by Bacillus cereus Isolate for Its Possible Application in Environmental Sustainability

Volume 1

Journal: Sustainable Processes Connect
open-access Research Article

Published: 15 Aug 2025

Evaluation of Anti-Inflammatory and Anticancer Activities of Maerua angolensis DC. Leaf Extract-Loaded Chitosan Nanoparticles

Volume 2

Journal: Biomaterials Connect
open-access Research Article

Published: 25 Aug 2025

The Effect of Demineralized Autogenous Tooth Block Bone on Lateral Sinus Augmentation: A Retrospective Study

Volume 2

Journal: Biomaterials Connect
open-access Research Article

Published: 25 Jul 2025

Structural and Molecular Changes of Isonicotinylhydrazine Anti-Tubercular Drug in Alcohol Environment: An Intuition from Theory

Volume 2

Journal: Molecular Modeling Connect
open-access Review Article

Published: 23 Jul 2025

Black Soldier Fly Larva: A Resource Insect Larva Worth Promoting in Achieving Sustainable Development Goals—A Systematic Review

Volume 1

Journal: Sustainable Food Connect
open-access Research Article

Published: 04 Aug 2025

Porous Structure and Characterization of Activated Carbons from the Grape Stalks

Volume 1

Journal: Sustainable Processes Connect
open-access Research Article

Published: 21 Jul 2025

AI Enabled Facial Emotion Recognition Using Low-Cost Thermal Cameras

Volume 2

While expensive hardware has historically dominated emotion recognition, our research explores the viability of cost-effective alternatives by utilising IoT-based low-resolution cameras with Vision Transformers (ViTs) and Convolutional Neural Networks (CNNs). In this work, we introduce a novel dataset specifically for thermal facial expression recognition and conduct a comprehensive performance analysis using ResNet, a standard ViT model developed by Google, and a modified ViT model tailored to be trained on smaller..

Journal: Computing&AI Connect
open-access Research Article

Published: 21 Jul 2025

A Novel MLLM-Based Approach for Autonomous Driving in Different Weather Conditions

Volume 2

Journal: Computing&AI Connect
open-access Research Article

Published: 14 Jul 2025

Exploring a Hybrid Deep Learning Framework to Automatically Discover Topic and Sentiment in COVID-19 Tweets

Volume 2

COVID-19 has created a major public health problem worldwide and other issues such as economic crisis, unemployment, mental distress, etc. The pandemic has affected people not only through infection but also by causing stress, worry, fear, resentment, and even hatred. Twitter is a highly influential social media platform and a major source of health-related information, news, opinions, and public sentiment, with content shared by both individuals and official government sources...

Journal: Computing&AI Connect
open-access Research Article

Published: 27 Jun 2025

Vascularized Organoid-on-Chip Platforms: Expanding the Bioengineering Frontiers with Microfluidics

Volume 2

Organoids-on-a-chip (OoC) technology is a pivotal advancement in biomedical research, engineered to meticulously replicate the intricate physiological functions of organs within controlled in vitro microenvironments. A critical component for elevating the biological fidelity and physiological relevance of these advanced platforms is the integration of a functional vascular system, vital for delivering nutrients and oxygen, waste removal, and intricate cell-cell communication. In this context, microfluidic technology has proven to be a..

Journal: Biomaterials Connect
open-access Research Article

Published: 27 Jun 2025

The Impact of Toxic Effector Molecule TagX on the Amino Acid Conformation of the Hcp1 Monohexameric Ring in Acinetobacter baumannii Type VI Secretion System Utilizing Bioinformatics Tools and an AI System

Volume 2

Journal: Molecular Modeling Connect
open-access Editorial

Published: 07 Jul 2025

The Predictive Revolution: Rethinking Science Through Molecular Modeling

Volume 2

Journal: Molecular Modeling Connect
open-access Research Article

Published: 23 Jun 2025

Descriptive Analysis of Reported Adverse Events Associated with Metoclopramide Using FDA Adverse Event Reporting System Databases

Volume 1

Journal: Clinical Pharmacy Connect
open-access Review Article

Published: 24 Jun 2025

Epigenetic Insights into Bladder Cancer: The Role of Urine DNA Methylation Assays: Mini Review

Volume 2

Bladder cancer remains a major global health challenge due to its high incidence, recurrence rates, and reliance on invasive diagnostic procedures. While conventional methods, such as cystoscopy and urine cytology, are considered standard, they often demonstrate limited sensitivity, particularly in detecting early-stage disease. Epigenetic alterations, particularly DNA methylation, are now recognized as critical in bladder cancer development and progression. Non-invasive urine-based DNA methylation assays have emerged as promising diagnostic and..

Journal: GenoMed Connect
open-access Research Article

Published: 23 Jun 2025

Clinical Diversity and Outcomes of Progressive Familial Intrahepatic Cholestasis Diagnosed by Whole Genome Sequencing in Pakistani Children

Volume 2

Progressive familial intrahepatic cholestasis (PFIC) is a rare group of genetic disorders that typically presents in infants and children, often progressing to end-stage liver disease. We used whole genome sequencing (WGS) for diagnosis to assess phenotypic features and outcomes in Pakistani children with different types of PFIC. The study included 116 pediatric participants with five PFIC types: PFIC1, ATP8B1 gene (n = 19); PFIC2, ABCB11 (n = 28); PFIC3, ABCB4..

Journal: GenoMed Connect
open-access Review Article

Published: 17 Jun 2025

The Intratumor Microbiome: An Untapped Avenue for Translational Applications in Cancer Immunotherapeutics

Volume 1

Journal: Cancer Research and Therapy Connect
open-access Research Article

Published: 26 Jun 2025

Dynamic Information Security Systems through Adaptive Architecture

Volume 2

The manufacturing industry is at the forefront of a digital transformation that promises significant enhancements in product and service quality. However, this technological shift also raises concerns about data security and information protection. In response to these challenges, a research study was conducted to investigate cybersecurity incidents in the manufacturers and assess the effectiveness of the Zero-Trust Architecture (ZTA) as a solution. The primary objectives of this research were to..

Journal: Communications & Networks Connect
open-access Review Article

Published: 23 Jun 2025

Quantum-Safe Networks for 6G: An Integrated Survey on PQC, QKD, and Satellite QKD with Future Perspectives

Volume 2

Quantum computing poses significant challenges to the current cryptographic landscape, particularly with the upcoming deployment of 6G networks. Traditional cryptographic algorithms, such as Rivest-Shamir-Adleman (RSA) and Elliptic Curve Cryptography (ECC), are vulnerable to quantum-based attacks. This vulnerability has led to the development of Post-Quantum Cryptography (PQC), Quantum Key Distribution (QKD), and Satellite-based QKD solutions. This paper provides a comprehensive review of these quantum-safe technologies, discussing their integration within the context..

Journal: Computing&AI Connect
open-access Research Article

Published: 25 Jun 2025

Political Instability and the Treadmill of Production: Sustainable Urban Processes in Kabul City

Volume 1

Political instability and weak institutional governance have exacerbated environmental degradation in Kabul City, where the relentless treadmill of production continues to strain natural resources. This study examines how weak institutional governance, conflict, corruption, and economic pressures contribute to unsustainable environmental practices, intensifying pollution, deforestation, and resource depletion. As political instability weakens institutional capacities, regulatory enforcement diminishes, allowing industrial and urban expansion to proceed unchecked. The treadmill of production, driven by..

Journal: Sustainable Processes Connect
open-access Research Article

Published: 09 Jun 2025

Sustainable Processes and Planned Obsolescence in the Textile and Clothing Sector in Portugal

Volume 1

Journal: Sustainable Processes Connect
open-access Mini-Review

Published: 23 May 2025

Fatty Allies: How Short-Chain Fatty Acids Turn the Tumor Microenvironment Against Cancer

Volume 1

Journal: Cancer Research and Therapy Connect
open-access Research Article

Published: 27 Jun 2025

Characterizing the Reducing Properties of Biofuels in Activating Metal Catalysts of Refinery Processes

Volume 1

Journal: Sustainable Processes Connect
open-access Review Article

Published: 26 May 2025

A Review on the Cell-Penetrating Peptides

Volume 1

The therapeutic potential of biomacromolecules in treating various diseases is undeniable; however, their application is significantly limited by the inherent barrier function of the cell membrane. Cell-penetrating peptides (CPPs), a class of small peptides comprising fewer than 30 amino acids, have garnered considerable attention due to their exceptional ability to traverse cell membranes. These peptides ease the intracellular delivery of various macromolecules, such as proteins, polypeptides, and nucleic acids, thereby..

Journal: Cell Therapy & Engineering Connect
open-access Review Article

Published: 12 May 2025

Artificial Intelligence at the Crossroads of Engineering and Innovation

Volume 2

The field of Artificial Intelligence (AI) is progressively transforming various advanced engineering disciplines, including mechanical, civil, electrical, aerospace, environmental, and biomedical engineering, through improved design, manufacturing, maintenance, and optimization methodologies. Yet, the disjointed and specialized state of the art too frequently prevents the cross-disciplinary application of AI solutions due to disparate performance measures, which result in reduced knowledge transfer and exaggerated performance in segregated domains. This study overcomes these issues..

Journal: Computing&AI Connect
open-access Research Article

Published: 07 May 2025

Exploring Artesunate and Dihydroartemisinin for Mechanism on MMP-3 and MMP-13 via Molecular Docking and Molecular Dynamics

Volume 2

The application of natural products has drawn increasing attention in recent times. Artesunate (ART) and Dihydroartemisinin (DHA), being natural products with anti-inflammatory and cartilage protective capabilities, have shown potential in osteoarthritis (OA) treatment. OA is a highly prevalent degenerative joint disease globally, leading to a diminished quality of life and is a major cause of disability. Matrix metalloproteinase 3 (MMP-3) and MMP-13 play crucial roles in OA progression. Although ART..

Journal: Molecular Modeling Connect
open-access Review Article

Published: 15 May 2025

Current Standing and Future Potential of 3D Bioprinting and Biomaterials

Volume 2

Journal: Biomaterials Connect
open-access Review Article

Published: 28 Apr 2025

Synergistic Modulation of ER Stress and Insulin Potentiation Therapy for Enhanced Cancer Treatment

Volume 1

Cancer cells sustain rapid growth by reprogramming their metabolism to depend heavily on glycolysis, enhanced insulin signaling, and adaptive changes in the unfolded protein response (UPR). Insulin Potentiation Therapy (IPT) enhances the efficacy of chemotherapy by increasing insulin receptor expression, thereby improving the uptake of chemotherapeutic agents. Meanwhile, targeting endoplasmic reticulum (ER) stress disrupts the protein-folding machinery within cancer cells, steering them toward apoptosis. However, IPT faces several limitations, including..

Journal: Cell Therapy & Engineering Connect
open-access Research Article

Published: 30 Jun 2025

Effect of Acyl Chain Variation and Cholesterol on Structural and Dynamic Properties of Lipid Bilayer Probed by Simulation

Volume 2

Lipid ordering plays a crucial role in maintaining the mechanical strength of the lipid bilayer, which is influential in controlling biological functions. This is associated with the well-known phenomena of “phase state behavior” of the bilayer. The significant factors that influence phase state behavior are stimuli such as cholesterol, physiological conditions like temperature and pH, and the structure of the lipid molecule itself, which can differ either in the head..

Journal: Molecular Modeling Connect
open-access Research Article

Published: 06 May 2025

Comprehensive Classification of Web Tracking Systems: Technological Insights and Analysis

Volume 2

Web tracking (WT) systems are advanced technologies that are used to monitor and analyze online user behavior. Initially focused on HTML and static webpages, these systems have evolved with the proliferation of IoT, edge computing, and Big Data, encompassing a broad array of interconnected devices with APIs, interfaces, and computing nodes for interaction. WT systems are pivotal in technological innovation and business development, although trends like GDPR complicate data extraction..

Journal: Computing&AI Connect
open-access Research Article

Published: 07 May 2025

A Novel Transformer Reinforcement Learning-Based NFV Service Placement in MEC Networks

Volume 2

The advent of 5G networks has facilitated various Industry 4.0 applications requiring stringent Quality-of-Service (QoS) demands, notably Ultra-Reliable Low-Latency Communication (URLLC). Multi-Access Edge Computing (MEC) has emerged as a key technology to support these URLLC applications by bringing computational resources closer to the user, thus reducing latency. Meanwhile, Network Function Virtualization (NFV) supports 5G networks by offering flexibility and scalability in service provisioning across various applications. Despite their benefits, MEC..

Journal: Computing&AI Connect
open-access Research Article

Published: 15 May 2025

Preparation and Characterization of Biocompatible Hydrogels Based on a Chitosan-Polyacrylamide Copolymer

Volume 2

Journal: Biomaterials Connect
open-access Research Article

Published: 15 Apr 2025

Association of Expression of Immune Checkpoints in Tumor-Infiltrating CD4+ T Lymphocytes with Disease-Free Survival in Colorectal Cancer Patients

Volume 1

Journal: Cancer Research and Therapy Connect
open-access Research Article

Published: 21 Apr 2025

Identification of Hub Genes and Molecular Mechanisms of Association of PCOS, Breast, and Ovarian Cancers Using an Integrated Bioinformatics Analysis

Volume 2

Background: Oxidative stress plays a crucial role in various aspects of cancer and other diseases. While reactive oxygen species (ROS) serve as key signal molecules in physiological processes for the normal functioning of the female reproductive system, they have also been implicated in pathological processes such as polycystic ovary syndrome (PCOS). Some studies have reported a significantly higher risk of endometrial cancer in women with PCOS. However, the association of..

Journal: GenoMed Connect
open-access Research Article

Published: 20 Mar 2025

Food and Medicine Homology Substance in Cancer Treatment: Mechanism of Astragalus against Pancreatic Cancer

Volume 2

Journal: Molecular Modeling Connect
open-access Research Article

Published: 21 Mar 2025

Characteristics of Tumor Infiltrating Lymphocytes in Patients with Benign and Malignant Sinonasal Neoplasms

Volume 1

Introduction. Tumor infiltrating lymphocytes are a major component of sinonasal neoplasms, actively populating tumor tissue, yet their role remains poorly understood. The aim is to characterize subsets and functional profiles of tumor infiltrating lymphocytes in patients with benign and malignant sinonasal tumors. Materials and methods. Tumor infiltrating lymphocytes were isolated from the biopsy material of 58 patients: 18 with sinonasal malignancies, 23 with inverted papilloma and 17 with polypous rhinosinusitis..

Journal: Cancer Research and Therapy Connect
open-access Review Article

Published: 25 Jun 2025

Advanced Subtractive Manufacturing, Micromilling, and Laser Micromachining in Dentistry: Current Applications, Limitations, and Future Perspectives

Volume 2

Journal: Biomaterials Connect
open-access Editorial

Published: 07 Mar 2025

Clinical Pharmacy at the Crossroads: Advancing Care, Improving Outcomes

Volume 1

Clinical pharmacy has evolved from a field that focuses on the dispensing and distribution of medications to a modern, colossal field that is imperative to the patient-driven care [1,2]. Clinical pharmacists play a multifaceted and crucial role in patient care via integrating knowledge and skills into clinical practice, thereby contributing to improved health outcomes. Specifically, they design tailored pharmacotherapy that matches patients’ needs, with a focus on ensuring medication safety..

Journal: Clinical Pharmacy Connect
open-access Review Article

Published: 17 Mar 2025

Security and Privacy in the IIoT: Threats, Possible Security Countermeasures, and Future Challenges

Volume 2

Journal: Computing&AI Connect
open-access Review Article

Published: 21 Mar 2025

Upcycled Mesenchymal Stem Cells: Repurposing Biological Waste Towards Sustainable Regenerative Therapies

Volume 1

Journal: Cell Therapy & Engineering Connect
open-access Research Article

Published: 20 Mar 2025

Unusual Arrangement of Catalytic Loops of the Alcohol Dehydrogenase Enzyme During the Adsorption Process on a Graphitic Carbon Surface

Volume 2

Molecular dynamics simulations (MDs) were conducted to investigate the alcohol dehydrogenase (ADH) enzyme and its cofactor, nicotinamide adenine dinucleotide (NAD), solvated in an aqueous system on a graphite-carbon surface. The study focuses on key structural aspects of ADH, particularly its conformational changes, including the rotation of the catalytic domain, the coenzyme binding domain, and the rearrangement of the active center required for catalytic activation. MDs were performed for 100 ns..

Journal: Molecular Modeling Connect
open-access Review Article

Published: 19 Mar 2025

Soluble Biomarkers as Predictors of Response to Immunotherapy in Non-Small Cell Lung Cancer (NSCLC)-Insights from the Tumor Microenvironment Perspective

Volume 1

Lung cancer is the major cause of mortality worldwide with non-small cell lung cancer (NSCLC) contributing to 85% of the cases. FDA-approved immune checkpoint inhibitors (ICI), anti-PD-1, and anti-PD-L1 are widely used as a standard treatment. However, the response rate is limited and is observed in only 20–40% of the patients. Therefore, predictive and prognostic biomarkers are needed to help differentiate responders from non-responders, enabling a better understanding of disease..

Journal: Cancer Research and Therapy Connect
open-access Research Article

Published: 20 Mar 2025

Prediction of Cognitive Impairment Using a Deep Learning Autoencoder Algorithm from a Singapore Study

Volume 2

Dementia is a decline in cognitive function, typically diagnosed when the acquired impairment becomes severe enough to impact social or occupational functioning. Between no cognitive impairment (NCI) and dementia, there are many intermediate states. Predictive cognitive impairment can be useful for initiating treatment to prevent further brain damage. Several deep learning-based approaches have been proposed for the classification of Magnetic Resonance Imaging (MRI) to diagnose Alzheimer’s disease (AD) or dementia...

Journal: Computing&AI Connect
open-access Systematic Review

Published: 21 Mar 2025

Epidemiological Investigation and Assessment of HEVs in Shellfish Based on Meta-Analysis

Volume 1

Hepatitis E virus (HEV) is an acute zoonotic infectious disease that can cause hepatitis E and may even lead to death in severe cases. Porcine organisms are regarded as the natural hosts carrying hepatitis E virus, and it is also commonly found in other products. Meanwhile, shellfish are also one of the main hosts. The aim of this study was to estimate the global prevalence of hepatitis E virus in..

Journal: Sustainable Food Connect
open-access Mini-Review

Published: 11 Feb 2025

CRISPR-Cas9 is Revolutionizing AML Treatment as a Novel Therapy

Volume 1

This review explores the progression of CRISPR-Cas9 genome editing technology in gene therapy for acute myeloid leukemia. Acute Myeloid Leukemia, a serious blood cancer, presents formidable treatment obstacles and a dismal prognosis. Effective treatments for acute myeloid leukemia rely on a clear understanding of its intricate genetic mechanisms, and CRISPR-Cas9 technology offers precision and adaptability for targeting the disease’s oncogenic drivers. The dual intron-targeting method of CRISPR-Cas9 is showcased in..

Journal: Cancer Research and Therapy Connect
open-access Mini-Review

Published: 07 Mar 2025

Azilsartan Kamedoxomil: Solubility Enhancement Techniques

Volume 2

Journal: Biomaterials Connect
open-access Mini-Review

Published: 28 Feb 2025

A Mini Review on Used Medical Yarns in the Braiding Production Methods for Biomaterial Applications

Volume 2

Biomaterials are advanced materials that can be implanted within the body, depending on the required design criteria, usually as a result of the production of polymeric-based, and medical yarns by the braiding method. Braiding method is widely used in the production of biomaterials due to its advantages, including a high elastic modulus, high tensile strength, and high dimensional stability properties. The high biological and mechanical properties required in biomaterials depend..

Journal: Biomaterials Connect
open-access Review Article

Published: 21 Mar 2025

Traditional Strategies and Cutting-Edge Technologies Used for Animal Breeding: A Comprehensive Review

Volume 1

Food security continues to remain a critical challenge confronting humanity. Worldwide, the demand for food products is extensively increasing. Today, the research of generating transgenic organisms is one of the fastest-developing biotechnology fields, as it promises sustainability of agriculture and aquaculture. Many of the animals observed today, including top-quality agricultural breeds such as Holstein cows and Landrace swine, have undergone significant changes and are entirely distinct from their wild ancestors...

Journal: Sustainable Food Connect
open-access Research Article

Published: 10 Mar 2025

A Novel Approach towards Establishing Free Space Optical Inter Satellite Links beyond the Kármán Line

Volume 1

The rapid surge in the technological advancement of humanity calls for development of faster, reliable & effective communication methods between satellites orbiting in outer space. The infamous inter-satellite link technology, coupled with free space optical communication is a robust solution for the same. While establishing this for low earth orbit satellites, it is critical to ensure that the links established across the two satellites avoid the atmosphere, i.e., the links..

Journal: Communications & Networks Connect
open-access Perspective

Published: 28 Feb 2025

Precision Medicine for Autoimmunity: From CAAR-T Cells to AI-Driven CRISPR-Based Therapies, Challenges and Perspectives

Volume 2

This manuscript examines advancements in antigen-specific immunosuppression, as well as the potential and challenges of applying gene-editing technologies to autoimmune diseases driven by autoantibodies (AAbs). Current approved treatments fail to reach long-lived plasma cells (LLPCs), which may continue secreting pathogenic AAbs after immunobiological courses in some autoimmune illnesses. New approaches, some tested in vitro and some already undergoing clinical trials, such as the chimeric autoantibody receptor (CAAR)-T cells, BiTEs, affinity..

Journal: GenoMed Connect
open-access Review Article

Published: 28 Feb 2025

Advances in Microfluidic Bioprinting for Multi-Material Multi-Cellular Tissue Constructs

Volume 1

Journal: Cell Therapy & Engineering Connect
open-access Research Article

Published: 21 Jan 2025

Preparation and Characterization of Thermoplastic Grafted Chitosan Compositions with L-Lactide as Potential Material for 3D Printing

Volume 2

Journal: Biomaterials Connect
open-access Research Article

Published: 18 Mar 2025

Physical Layer Security in Lossy Untrusted Relay Networks with Finite Blocklength

Volume 1

In this paper, we examine the physical layer security (PLS) in lossy untrusted relay networks, focusing on finite blocklength transmissions. In such networks, ensuring secure communication is particularly challenging due to the presence of untrusted relay nodes and the inherent limitations of short-packet transmissions. We propose the reliable-and-secure probability (RSP) as a performance metric to evaluate the likelihood that the destination node successfully recovers the transmitted message while untrusted relays..

Journal: Communications & Networks Connect
open-access Editorial

Published: 15 Jan 2025

The Potential of Artificial Intelligence and Machine Learning in Pharmacovigilance: An Update

Volume 2

The integration of artificial intelligence (AI) and machine learning (ML) into pharmacovigilance (PV) marks a transformative step towards enhancing drug safety and patient outcomes. With their unparalleled ability to analyze vast and complex datasets, AI/ML technologies offer unprecedented opportunities to revolutionize adverse drug event (ADE) monitoring, signal detection, and causality assessment. This editorial explores the state-of-the-art applications, key challenges, and actionable strategies to unlock the full potential of AI in..

Journal: GenoMed Connect
open-access Editorial

Published: 31 Dec 2024

Preface

Volume 1

Welcome to the inaugural volume of the Computing & AI Connect (CAIC) Journal, a peer-reviewed, open-access journal committed to fostering advancements and innovation in computing sciences and technologies, and artificial intelligence. CAIC is a platform that is dedicated to exploring the profound and transformative impacts of computing and artificial intelligence on the different aspects of life. In recent years, AI has become the focus of researchers from different fields, working to..

Journal: Computing&AI Connect
open-access Review Article

Published: 08 Jan 2025

Chronic Myelomonocytic Leukemia Relapse After Transplant

Volume 1

Relapse of Chronic Myelomonocytic Leukemia after allogeneic hematopoietic stem cell transplantation remains a significant challenge, with relapse rates reaching up to 50%, contributing to poor survival outcomes. This paper explores the factors influencing relapse, including disease biology and persistence of residual disease. Current, post- transplant strategies, such as maintenance therapies and immunomodulatory treatments, are discussed for their potential to reduce the likelihood of relapse. It also highlights emerging therapies, such..

Journal: Cancer Research and Therapy Connect
open-access Review Article

Published: 01 Jan 2025

Nanotechnology Based Drug Delivery Systems of Herbal Medicine

Volume 2

Journal: Biomaterials Connect
open-access Research Article

Published: 04 Apr 2025

Smart Gas Sensing by (Al/C/Si)-Doped Boron Nitride Nanomaterial Towards Grabbing Nitric Oxide: A Novel Applied Technique for Air Pollution Reduction by DFT Analysis

Volume 2

The electronic, magnetic, and thermodynamic properties of adsorption of toxic gases, including Nitric oxide (NO) by using Y (Y = Al, C, Si)-doped boron nitride nanocage (BN) have been investigated using density functional theory (DFT). The results denote that NO→Y–BN are stable compounds, with the most stable adsorption site being the center of the cage ring. Furthermore, the reported results of nuclear magnetic resonance (NMR) spectroscopy have exhibited the strength..

Journal: Molecular Modeling Connect
open-access Research Article

Published: 26 Dec 2024

Study of the 3-(3,3-Dimethylbutanoyl)-4-hydroxy-6-neopentyl-2H-pyran-2-one by IR, Raman spectroscopy, and DFT

Volume 1

The heterocyclic structure of pyrones has a variety of biological activities and plays an important role in the creation of new drugs. Therefore, the study of the structure and spectra of pyrones is of considerable interest. In this work, the IR and Raman spectra of 3-(3,3-Dimethylbutanoyl)-4-hydroxy-6-neopentyl-2H-pyran-2-one (1) in its crystalline state was studied. The tautomerization of 1 was followed by a quantum-chemical method at the DFT/B3LYP/6-311G** level. The calculation for..

Journal: Molecular Modeling Connect
open-access Review Article

Published: 31 Dec 2024

Distributed Reinforcement Learning for IoT Security in Heterogeneous and Distributed Networks

Volume 1

Journal: Computing&AI Connect
open-access Editorial

Published: 28 Nov 2024

Preface

Volume 1

It is both an honor and a privilege to introduce this inaugural issue of Biomaterials Connect. Biomaterials Connect is a newly established journal that intends to be an inclusive forum for all researchers, scientists, engineers, and professionals working within the various fields of biomaterials science. The purpose is to encourage the contribution to multi-disciplinary interaction, the diffusion of new ideas, and contributing to biomaterials research and applications, but in particular..

Journal: Biomaterials Connect
open-access Systematic Review

Published: 07 Feb 2025

A Systematic Review on Integrating Artificial Intelligence for Enhanced Fault Detection in Power Transmission Systems: A Smart Grid Approach

Volume 2

Modern electrical systems rely on sensors and relays for fault detection in three-phase transmission lines and distribution transformers, but these devices often face time complexity issues and false alarms. In this study, the fault detection accuracy is compared in models studied in 2023 and 2024 following PRISMA guidelines. The objectives were to identify fault types, utilize machine learning models to assess their predictive efficacy, and establish accuracy levels. To explore..

Journal: Computing&AI Connect
open-access Case Report

Published: 29 Nov 2024

Epidermolytic Hyperkeratosis Type 1 with a New Heterozygous Mutation in KRT1 Gene: A Case Report

Volume 1

Background: Epidermolytic hyperkeratosis (EHK) formerly known as bullous ichthyosiform erythroderma, is a rare autosomal dominant inheritance condition with a prevalence ranging from 1:200,000 to 1:300,000. The underlying etiology of which is a mutation in the genes responsible for keratin proteins synthesis, primarily in KRT1 and KRT10 genes, cataloged under OMIM number 113800. The clinicopathological presentations include blistering during the neonatal period, followed by ichthyotic hyperkeratosis in childhood and adolescence. This..

Journal: GenoMed Connect
open-access Research Article

Published: 12 Dec 2024

Social Media and Artificial Intelligence for Sustainable Cities and Societies: A Water Quality Analysis Use-Case

Volume 1

Crowd-sourcing has been widely explored for monitoring and feedback on infrastructure and services, such as air and water quality analysis. However, the traditional methods of crowd-sourcing for feedback and analysis of water quality, namely offline and online surveys, have several limitations, such as the limited number of participants and low frequency due to the labor involved in conducting such surveys. Social media analytics could overcome these challenges by providing a..

Journal: Computing&AI Connect
open-access Research Article

Published: 20 Nov 2024

Impact of Surface Modification of Hemp Fibers Using a Coupling Agent in Solvent on the Properties of Polyethylene Composites

Volume 1

This study investigates the grafting of a coupling agent, maleic anhydride-grafted polyethylene (MAPE), onto hemp fibers in a 1,2,4-trichlorobenzene (TCB) solution, followed by an evaluation of the morphological, rheological, and mechanical properties of the resulting polyethylene composites containing 30% hemp. SEM analysis revealed the formation of a thin layer of MAPE on the surface of the modified fibers. This was further confirmed by the appearance of a MAPE degradation peak..

Journal: Biomaterials Connect
open-access Letter

Published: 05 Nov 2024

Arsenic, Mercury, Lead and Iron Induced Lipid Peroxidation in Phospholipids Liposomes and Protective Effect of Fumaric Acid

Volume 1

Journal: Sustainable Food Connect
open-access Review Article

Published: 25 Oct 2024

Review on Next-Gen Healthcare: The Role of MEMS and Nanomaterials in Enhancing Diagnostic and Therapeutic Outcomes

Volume 1

The convergence of microelectromechanical systems (MEMS) and nanomaterials is transforming healthcare by enabling diagnostics, drug delivery, and biosensing breakthroughs. This synergistic integration offers unprecedented precision, miniaturization, and biocompatibility, overcoming critical challenges in detecting disease markers and delivering therapies. When combined with nanomaterials, MEMS-based devices achieve heightened sensitivity and specificity, allowing for early diagnosis and targeted treatments across various medical applications. This fusion holds immense potential in advancing personalized medicine, from..

Journal: Biomaterials Connect
open-access Research Article

Published: 13 Dec 2024

Refining the Scrum Paradigm: A Comprehensive Research of Software Development Practices (2020–2023)

Volume 1

This article presents a complex vision on software production practices aimed at enhancing the Scrum methodology within software project management. The recommended best practices are closely aligned with contemporary trends in the IT sector, including the total digitalization and virtualization of production processes, the transition to fully remote software development models, the incorporation of artificial intelligence technologies, and the implementation of cost-effective models in team organization. The modifications to software..

Journal: Computing&AI Connect
open-access Review Article

Published: 18 Nov 2024

Biofunctional Applications of Chitosan in Dentistry - An Overview

Volume 1

Chitosan, with its unique properties, has garnered the interest of materials scientists worldwide, leading to exploration in bio-dental applications. In dentistry, chitosan has shown a wide range of applications. The creation of effective biomaterials for the prevention and treatment of dental disorders is a challenge for researchers in the present scenario. The natural semi-synthetic polysaccharide-based biomaterial Chitosan is derived from chitin, which is sourced from marine organisms. Due to its..

Journal: Biomaterials Connect
open-access Research Article

Published: 05 Nov 2024

Evaluation of IL 12 Gene Expression and Serum Levels of OxPL / apoB in Patients with Coronary Artery Disease

Volume 1

Background Atherosclerotic lesions are formed as a result of low-density lipoprotein (LDL) accumulation, which is produced by oxidizing enzymes and oxidized phospholipids (OxPL). Phospholipid oxide causes inflammation-inducing activation genes and hyper-inflammation in addition to the initiation of inflammation and expression of Th1 cytokines. Interleukin 12 (IL-12) is one of the most significant stimulants of inflammation and immune responses, among the Th1cytokines. Therefore, it may play a significant role in contributing..

Journal: GenoMed Connect
open-access Research Article

Published: 24 Oct 2024

Preparation and Characterization of Acetate Cellulose Laurate Ester in Sodium Acetate/Zinc Chloride Systems

Volume 1

The objective of this study was to explore the preparation and characterization of acetate cellulose laurate ester in sodium acetate/zinc chloride systems. The cellulose used in the study was obtained from oil palm empty fruit bunch and oil palm frond. The characterization of both the isolated cellulose and the acetate cellulose laurate ester was carried out using Fourier transform infrared spectroscopy (FTIR), X-ray diffraction (XRD), Differential thermogravimetric (DTG), and Thermogravimetric..

Journal: Biomaterials Connect
open-access Review Article

Published: 21 Oct 2024

Neoantigen-Based Cancer Vaccines: Current Innovations, Challenges and Future Directions in Personalized Immunotherapy

Volume 1

Journal: Cancer Research and Therapy Connect
open-access Editorial

Published: 11 Oct 2024

Exploring a New Era in Cell Engineering

Volume 1

As the Editor-in-Chief of Cell Engineering Connect, it is both an honor and a privilege to introduce this inaugural issue. Our journal is dedicated to exploring the latest advancements in the rapidly evolving field of cell engineering, an interdisciplinary domain that holds the key to transformative innovations in healthcare, biotechnology, and synthetic biology. The convergence of cell biology, bioengineering, and data science is enabling researchers to manipulate cellular systems in..

Journal: Cell Therapy & Engineering Connect
open-access Research Article

Published: 28 Sep 2024

Towards Low Complexity VLC Systems: A Multi-Task Learning Approach

Volume 1

In the rapidly evolving landscape of wireless communication, visible light communication (VLC) stands out for its potential to redefine high-speed data exchange. Recently, VLC has utilized waveforms that combine multiple bitstreams in a unified physical layer, allowing for high-speed data exchange, precise localization, and robust control simultaneously. Particularly, the demodulation tasks of beacon position modulation (BPM) and beacon phase shift keying (BePSK) are central to decoding of such waveforms and..

Journal: Communications & Networks Connect
open-access Research Article

Published: 17 Oct 2024

In Silico Investigation of the Constituents of Aroeira Honey (Astronium urundeuva) and the Binding Affinity with Important Proteins of M. leprae and M. tuberculosis

Volume 1

Journal: Molecular Modeling Connect
open-access Research Article

Published: 17 Oct 2024

Investigation of TLR4, TLR6, TLR7, and CD36 Expression on T lymphocytes in Coronary Artery Disease

Volume 1

Background: Coronary artery disease (CAD) is among the significant causes of death globally, caused by fatty deposits in blood vessel walls. Increasing evidence indicates that toll-like receptors (TLRs) are pivotal to atherosclerosis progression. The function of CD36 as a glycoprotein in atherosclerosis was also suggested. This study aimed to investigate the levels of TLR4, TLR6, and TLR7, as well as CD36 cell surface markers in CAD. Methods: This study included..

Journal: GenoMed Connect
open-access Research Article

Published: 14 Nov 2024

Metal Ions Released During Canine Retraction Using Fixed Orthodontic Appliance: Prospective Clinical Study

Volume 1

Background: Metal ions released from dental alloys pose a significant concern due to their potential local and systemic effects. One of these effects is hypersensitivity, particularly associated with nickel-containing dental alloys. Aim: to measure metal ion concentration in saliva during orthodontic space closure on a 0.019X0.025 working archwire. Material and Methods: Trial design: Controlled clinical trial. Setting: Orthodontic treatment was provided at the Postgraduate Orthodontic Teaching Clinics and saliva testing..

Journal: Biomaterials Connect
open-access Research Article

Published: 10 Sep 2024

Diversity of HLA Class I and II Genes in the North Indian Population

Volume 1

Introduction: Numerous studies have concentrated on specific populations to explore the extensive polymorphism of class I and II HLA genes. This genetic diversity is crucial for various applications, such as advancing transplantation immunology, understanding genetic population patterns, and uncovering the pathways of different diseases. Objective: The objective of the present study was to determine and analyse the frequencies of class I (HLA-A, HLA-B and, HLA-C), and class II (HLA-DRB1, and..

Journal: GenoMed Connect
open-access Review Article

Published: 29 Aug 2024

Ethical Approaches in Secondary Findings Report from Exome Sequencing Analysis

Volume 1

In Whole Exome Sequencing (WES) and Whole Genome Sequencing (WGS) approaches, incidental findings (IFs) or more precisely secondary findings (SFs) have indicated controversial reports. To address SFs issues, well-known guidelines have been released such as the versions of the American College of Medical Genetics and Genomics (ACMG); however, when, to whom, why, and how these SFs should be reported are the key questions that need to be addressed ethically. The..

Journal: GenoMed Connect
open-access Review Article

Published: 23 Aug 2024

The Secret Life of Microbes: The Expanding Role of Microbes in Shaping Endocrine Health—The Role of Microbes in Endocrinology Health

Volume 1

This review was intended to attempt to establish the complex association between the endocrine system of the host and the gut microbiota. Microbial endocrinology is a relatively new field of study, which examines how microbes regulate hormonal; and affect metabolisms, immune system, and behavior responses. This is because the gut microbiome can be viewed as a virtual endocrine organ as it is involved in the synthesis of neuroactive substances as..

Journal: GenoMed Connect
open-access Review Article

Published: 28 Aug 2024

An Overview of Secure Network Segmentation in Connected IIoT Environments

Volume 1

Journal: Computing&AI Connect
open-access Research Article

Published: 23 Aug 2024

Challenging Conventions Towards Reliable Robot Navigation Using Deep Reinforcement Learning

Volume 1

Effective indoor navigation in the presence of dynamic obstacles is crucial for mobile robots. Previous research on deep reinforcement learning (DRL) for robot navigation has primarily focused on expanding neural network (NN) architectures and optimizing hardware setups. However, the impact of other critical factors, such as backward motion enablement, frame stacking buffer size, and the design of the behavioral reward function, on DRL-based navigation remains relatively unexplored. To address this..

Journal: Computing&AI Connect
open-access Research Article

Published: 29 Jul 2024

Mirror, Mirror on the Wall: Automating Dental Smile Analysis with AI in Smart Mirrors

Volume 1

Journal: Computing&AI Connect
open-access Research Article

Published: 29 Jul 2024

Translucency and Polymerization Ability of Contemporary Resin Composites

Volume 1

Objective: The present study aimed to characterize the translucency and polymerization ability of commercially available contemporary resin composites. Methods: The resin composites considered in this study were Forma (Enamel, Body, and Dentin; Ultradent), Empress Direct (Enamel and Dentin; Ivoclar/Vivadent), Sirius-Z (Enamel and Dentin; DFL), and Orion (Enamel and Dentin; DFL). All photoactivation procedures were performed using the same light source (Valo Cordless, 30 s). The translucency parameter (TP) was determined..

Journal: Biomaterials Connect
open-access Review Article

Published: 13 Jun 2024

Hierarchical Autoencoder-Based Lossy Compression for Large-Scale High-Resolution Scientific Data

Volume 1

Lossy compression has become an essential technique to reduce data size in many domains. This type of compression is especially valuable for large-scale scientific data, whose size ranges up to several petabytes. Although Autoencoder-based models have been successfully leveraged to compress images and videos, such neural networks have not widely gained attention in the scientific data domain. Our work presents a neural network that not only significantly compresses large-scale scientific..

Journal: Computing&AI Connect
open-access Editorial

Published: 12 Aug 2026

Editorial

Volume 1

It is my pleasure to present the inaugural issue of Ecological and Sustainable Materials Connect. This new journal aims to provide a platform for researchers, scientists, engineers, and practitioners across various fields who are committed to developing sustainable solutions and improving design options to create better sustainable societies and produce efficient, eco-friendly bio-products in the future. We aim to foster multidisciplinary cooperation, facilitate the exchange of innovative ideas, and promote..

Journal: Ecological & Sustainable Materials Connect
open-access Editorial

Published: 31 Dec 2025

Shaping the Next Chapter of Biomaterials Innovation

Volume 2

Welcome to the 2nd volume of Biomaterials Connect. The published articles provide valuable examples and highlight the seamless integration of digital design and fabrication, the convergence of nanotechnology and biological systems, and the translation of fundamental scientific discoveries into clinically relevant solutions. Collectively, they offer a clear vision of the future of biomaterials science. A common theme across these contributions is the continued development of intelligent, high-performance biomaterials. Nanotechnology remains..

Journal: Biomaterials Connect
open-access Editorial

Published: 31 Dec 2025

Preface

Volume 1

The completion of Volume 1 represents a significant milestone in the establishment and development of our journal. This inaugural volume reflects our firm commitment to advancing high-quality, peer-reviewed process within the interconnected fields of food systems, agricultural innovation, environmental health, and sustainability. The contributions published in this volume demonstrate both scientific rigor and thematic breadth. They address critical and contemporary issues, including sustainability-driven neuromarketing in the food and agribusiness sector,..

Journal: Sustainable Food Connect
open-access Editorial

Published: 31 Dec 2025

Advancing Sustainable Food Systems Through Science, Innovation and Collaboration

Volume 1

As the Editor-in-Chief, I am delighted to welcome readers, researchers, and practitioners to Sustainable Food Connect, a journal proudly published by Scifiniti. It is an open-access, peer-reviewed journal dedicated to shaping the future of food systems by addressing global food challenges through sustainable and environmentally responsible approaches across the entire value chain, including sustainable production, processing, and consumption practices, the development of commercially viable food products, and the advancement of..

Journal: Sustainable Food Connect
open-access Editorial

Published: 30 Dec 2025

Preface

Volume 1

It is my honor as Editor-in-Chief to present the first volume of Cancer Immunology Connect, a new peer-reviewed journal focused on the rapidly advancing fields of cancer immunology and immunotherapy. The aim of this first volume and of subsequent publications is to deepen our understanding of the molecular and cellular drivers of cancer and to highlight strategies that selectively target these molecules or pathways to improve therapeutic efficacy and patient..

Journal: Cancer Research and Therapy Connect
open-access Editorial

Published: 29 Dec 2025

Preface

Volume 1

Greetings from the Editor-in-Chief of the Journal of Sustainable Processes Connect. I am privileged to take this opportunity to express my sincere gratitude to our readers, innovative authors, enthusiastic expert reviewers, and our distinguished and diverse editorial board for being an integral part of the Journal. Distinctly, the year 2025 could be identified as the promising beginning of the Journal and a year of continuous sustainable growth and discovery. I..

Journal: Sustainable Processes Connect
open-access Editorial

Published: 25 Dec 2025

Preface

Volume 1

Welcome to the inaugural volume of the Clinical Pharmacy Connect Journal, a peer-reviewed journal that aims to publish original, high-quality research, reviews, and communications on the latest developments in all areas of pharmacy practice. The rapid advancements in clinical pharmacy have necessitated a dedicated platform for scholarly exchange, rigorous peer review, and the dissemination of innovative research. We have assembled a diverse editorial board, and we are committed to a..

Journal: Clinical Pharmacy Connect
open-access Editorial

Published: 08 Dec 2025

Emerging Nanotechnologies in Pharmaceutical Sciences: Opportunities and Challenges

Volume 1

It is my honor to serve as the Editor-in-Chief of Pharmaceuticals and Nanotech Connect, a newly established journal by Scifiniti, and to introduce its inaugural issue. Our journal provides a dynamic platform that bridges recent advancements in nanotechnology and conventional pharmaceutical sciences, fostering innovation and translational research while promoting the global integration of education, research, and practice in pharmacy and nanotechnology. The focus of this journal is to disseminate creative..

Journal: Pharmaceuticals and Nanotech Connect
open-access Editorial

Published: 21 Jul 2025

Preface

Volume 1

As Editor-in-Chief of Cell Therapy & Engineering (CTE) Connect, it is my great pleasure to welcome you to the volume of CTE Connect - a peer-reviewed, open-access journal envisioned as a global stage for breakthroughs that merge fundamental cell engineering with transformative clinical and industrial applications. CTE Connect will follow a continuous publication model in print and online, ensuring that high-quality science is freely accessible to practitioners, scholars, and innovators..

Journal: Cell Therapy & Engineering Connect
open-access Editorial

Published: 28 Mar 2025

Preface

Volume 1

Welcome to the inaugural volume of Comm&Optics Connect, a multidisciplinary journal dedicated to advancing communication and networks across the entire electromagnetic spectrum. This first volume embodies our vision to provide a platform where groundbreaking research in radio, mmWave, THz, and optical technologies converges. The future of communication networks lies in the seamless integration of technologies across the electromagnetic spectrum to support ultra-high speed, ultra-low latency, and massive connectivity. However, realizing..

Journal: Communications & Networks Connect
open-access Research Article

Published: 09 Jan 2025

How Caffeine Affects Alpha-Amylase: An In Vivo Study

Volume 2

Background: Caffeine is a widely consumed psychostimulant with various effects, including weight and metabolic parameters. Caffeine consumption has been associated with increased blood glucose levels and reduced insulin sensitivity. Since xanthine derivatives like caffeine can activate alpha-amylase, an enzyme essential for carbohydrate-to-glucose conversion, this study investigates whether this translates to increased amylase activity in living organisms and explores potential gene expression changes. Methods: Male NMRI mice were divided to 5..

Journal: GenoMed Connect
open-access Research Article

Published: 12 Dec 2024

The Placement of Auer Rods as a Single Diagnostic Criterion for the Highest-Risk Category of Myelodysplastic Syndromes: A Single-Institution Study and Critical Analysis

Volume 2

Accurate determination of prognostic risk is critical for patients and treating clinicians. The French-American-British classification of myelodysplastic syndromes (MDS) described refractory anemia with excess blasts (RAEB) in transformation (RAEB-T), including two subsets with <20% bone marrow (BM) blasts, which were reclassified as RAEB-2, the highest-risk MDS category in the 2001 World Health Organization classification. Those diagnostic criteria have been retained until now with nomenclature changes from RAEB-2 to “MDS with..

Journal: GenoMed Connect
open-access Editorial

Published: 30 Nov 2024

Preface

Volume 1

As Editor-in-Chief of GenoMed Connect, it is my great pleasure to introduce the inaugural issue of this journal, dedicated to bridging the fields of genomics and medicine. Our vision for GenoMed Connect is to serve as a platform for the latest research that informs precision medicine and promotes integrative healthcare approaches. This inaugural issue features a diverse collection of seven articles, showcasing the journal's commitment to interdisciplinary research and its..

Journal: GenoMed Connect
open-access Research Article

Published: 19 Nov 2024

Technological Trends in Open Fronthauls for Beyond 5G and 6G Networks

Volume 1

Ultra-massive interconnection composed of extremely small to minuscule networks that are significantly overloaded is required for the fifth generation (5G) and the next sixth generation (6G) networks. In order to meet the demands for network flexibility, complete coverage, and huge access, the conventional radio access network (RAN) will be completely revamped. This study focuses on the technological trends in the requirements-fulfilling Open RAN (ORAN) architecture and essential technologies in this..

Journal: Communications & Networks Connect
open-access Research Article

Published: 23 Sep 2024

Identification of Prognostic Biomarkers and Tumor Immune Microenvironment about Uveal Melanoma

Volume 1

Uveal melanoma (UM) is a malignant eye cancer that has a high mortality rate and is notoriously difficult to diagnose clinically. Identifying prognostic biomarkers and evaluating the tumor immune microenvironment for UM in order to improve diagnosis, treatment decisions and even overall survival for patients. The study involved a comprehensive analysis of transcriptome profiling from the TCGA-UVM project, with the aim of identifying biomarkers and exploring the relationship between the..

Journal: GenoMed Connect
open-access Editorial

Published: 10 Sep 2024

3D Printing of Biomaterials: Is It Disruptive or Destructive?

Volume 1

3D printing represents a new era in the field of digital manufacturing, finding its applications in many industries, such as healthcare, automotive, and aerospace. In particular, 3D printing has the potential to completely revolutionize the manufacturing process for implants, medical equipment, and even human tissues within the healthcare industry. The rapid rise of 3D printing raises fundamental questions i.e., Is this technology truly revolutionary, or does it perhaps take us..

Journal: Biomaterials Connect
open-access Research Article

Published: 10 Sep 2024

A Cloud Based IoT Electricity Consumption Monitoring Platform for a Residential Household

Volume 1

Energy costs are a concern, given the rate of increase in energy costs. The unprecedented switch to electricity as a source of energy is reflected in the growth of the electric vehicle, solar panel and heat pump markets as consumers compete with reducing fossil energy consumption. This paper evaluates electricity usage in two households, namely Household A and Household B using energy kilowatt hour, power wattage and the outside weather..

Journal: Communications & Networks Connect
open-access Research Article

Available Online: 01 Jan 1970

Prediction of natural fiber composite mechanical properties with a multilayer artificial neural network

Volume 1

For environmental and cost reasons that have gained acceptance across the globe, natural fiber–reinforced composites have been adopted in all sorts of applications currently. However, these composites are a production challenges, such as poor adhesion between reinforcement and matrix. Consequently, a comprehensive Artificial Neural Network (ANN) framework to predict the mechanical properties of green composites, especially for Ultimate Tensile Strength (UTS) and Young's Modulus, is adopted, to reduce the experimental..

Journal: Ecological & Sustainable Materials Connect
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