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362<div class="dialog-off-canvas-main-canvas" data-off-canvas-main-canvas> 363 364 365 366 367<div class="layout-container"> 368 369 370 371 372 373<div id="block-block-otsuka-ds3-abilifyasimhcc-messages" id="block-otsuka-ds3-abilifyasimhcc-messages" class="system"> 374 375 376 <div class="container"> 377 <div data-drupal-messages-fallback class="hidden"></div> 378 </div> 379 </div> 380 381 382 383 384 385 386<header id="block-homenavigation" class="header d-flex flex-column justify-content-center segmentation block-content-home-navigation block-content-paragraphs"> 387 388 <div class="header-top text-center"> 389 390 391 392 393 394 395 396 397<ul class="site-switcher site-switcher-- list-unstyled"> 398 399 400 401 402<li class="site-switcher__item site-switcher__item--with-sub site-switcher__item--dropdown nav-item dropdown" > 403 404 405 406 407 408 409 <button target="_self" class="site-switcher-link dropdown-toggle nav-link" data-bs-toggle="dropdown" data-item-title="Bipolar I Disorder" type="button"> <span>Bipolar I Disorder</span> 410 </button> 411 412 413 414 415<ul class="site-switcher site-switcher--sub site-switcher--sub-1 dropdown-menu list-unstyled"> 416 417 418 419 420<li class="site-switcher__item site-switcher__item--sub site-switcher__item--sub-1 nav-item dropdown" > 421 422 423 424 425 426 427 <a href="/bipolar-I" target="_self" class="site-switcher-link dropdown-item" data-item-title="Bipolar I Disorder" data-drupal-link-system-path="node/166"> <span>Bipolar I Disorder</span> 428 </a> 429 </li> 430 431 432 433<li class="site-switcher__item site-switcher__item--sub site-switcher__item--sub-1 nav-item dropdown" > 434 435 436 437 438 439 440 <a href="/schizophrenia" target="_self" class="site-switcher-link dropdown-item" data-item-title="Schizophrenia" data-drupal-link-system-path="node/226"> <span>Schizophrenia</span> 441 </a> 442 </li> 443 </ul> 444 445 </li> 446 </ul> 447 448 449 450 451 452 453 454 455 456 457<ul class="top-menu top-menu-- d-inline-flex list-unstyled"> 458 459 460 461 462<li class="top-menu__item top-menu__item--with-sub top-menu__item--dropdown nav-item dropdown" > 463 464 465 466 467 468 469 <button target="_self" class="first-button top-menu-link dropdown-toggle nav-link" data-bs-toggle="dropdown" data-item-title="U.S. Prescribing Information, including BOXED WARNING" type="button"> <span>U.S. Prescribing Information, including BOXED WARNING</span> 470 </button> 471 472 473 474 475<ul class="top-menu top-menu--sub top-menu--sub-1 dropdown-menu list-unstyled"> 476 477 478 479 480<li class="top-menu__item top-menu__item--sub top-menu__item--sub-1 nav-item dropdown" > 481 482 483 484 485 486 487 <a href="https://otsuka-us.com/media/static/Abilify-Asimtufii-PI.pdf" target="_blank" class="external-link-popup-disabled top-menu-link dropdown-item" data-item-title="ABILIFY ASIMTUFII<sup>®</sup> (aripiprazole)" aria-label="ABILIFY ASIMTUFII<sup>®</sup> (aripiprazole) (opens in a new window)"> <span>ABILIFY ASIMTUFII<sup>®</sup> (aripiprazole)</span> 488 </a> 489 </li> 490 491 492 493<li class="top-menu__item top-menu__item--sub top-menu__item--sub-1 nav-item dropdown" > 494 495 496 497 498 499 500 <a href="https://www.otsuka-us.com/media/static/Abilify-M-PI.pdf" target="_blank" class="external-link-popup-disabled top-menu-link dropdown-item" data-item-title="ABILIFY MAINTENA<sup>®</sup> (aripiprazole)" aria-label="ABILIFY MAINTENA<sup>®</sup> (aripiprazole) (opens in a new window)">
500 <span>ABILIFY MAINTENA<sup>®</sup> (aripiprazole)</span> 501 </a> 502 </li> 503 504 505 506<li class="top-menu__item top-menu__item--sub top-menu__item--sub-1 nav-item dropdown" > 507 508 509 510 511 512 513 <a href="https://www.otsuka-us.com/media/static/Abilify-PI.pdf" target="_blank" class="external-link-popup-disabled top-menu-link dropdown-item" data-item-title="ABILIFY<sup>®</sup> (aripiprazole)" aria-label="ABILIFY<sup>®</sup> (aripiprazole) (opens in a new window)"> <span>ABILIFY<sup>®</sup> (aripiprazole)</span> 514 </a> 515 </li> 516 </ul> 517 518 </li> 519 520 521 522<li class="top-menu__item top-menu__item--with-sub top-menu__item--dropdown nav-item dropdown" > 523 524 525 526 527 528 529 <button target="_self" class="second-button top-menu-link dropdown-toggle nav-link" data-bs-toggle="dropdown" data-item-title="Medication Guide" type="button"> <span>Medication Guide</span> 530 </button> 531 532 533 534 535<ul class="top-menu top-menu--sub top-menu--sub-1 dropdown-menu list-unstyled"> 536 537 538 539 540<li class="top-menu__item top-menu__item--sub top-menu__item--sub-1 nav-item dropdown" > 541 542 543 544 545 546 547 <a href="https://otsuka-us.com/media/static/Abilify-Asimtufii-MedGuide.pdf" target="_blank" rel="noreferrer noopener" class="external-link-popup-disabled top-menu-link dropdown-item" data-item-title="ABILIFY ASIMTUFII<sup>®</sup> (aripiprazole)" aria-label="ABILIFY ASIMTUFII<sup>®</sup> (aripiprazole) (opens in a new window)"> <span>ABILIFY ASIMTUFII<sup>®</sup> (aripiprazole)</span> 548 </a> 549 </li> 550 551 552 553<li class="top-menu__item top-menu__item--sub top-menu__item--sub-1 nav-item dropdown" > 554 555 556 557 558 559 560 <a href="https://www.otsuka-us.com/media/static/Abilify-M-Medguide.pdf" target="_blank" class="external-link-popup-disabled top-menu-link dropdown-item" data-item-title="ABILIFY MAINTENA<sup>®</sup> (aripiprazole)" aria-label="ABILIFY MAINTENA<sup>®</sup> (aripiprazole) (opens in a new window)"> <span>ABILIFY MAINTENA<sup>®</sup> (aripiprazole)</span> 561 </a> 562 </li> 563 564 565 566<li class="top-menu__item top-menu__item--sub top-menu__item--sub-1 nav-item dropdown" > 567 568 569 570 571 572 573 <a href="https://www.otsuka-us.com/media/static/Abilify-MedGuide.pdf" target="_blank" class="external-link-popup-disabled top-menu-link dropdown-item" data-item-title="ABILIFY<sup>®</sup> (aripiprazole)" aria-label="ABILIFY<sup>®</sup> (aripiprazole) (opens in a new window)"> <span>ABILIFY<sup>®</sup> (aripiprazole)</span> 574 </a> 575 </li> 576 </ul> 577 578 </li> 579 580 581 582<li class="top-menu__item nav-item" > 583 584 585 586 587 588 589 <a href="https://abilifyasimtufiihcp.com/" target="_blank" class="desktop-only top-menu-link nav-link" data-item-title="U.S. Healthcare Providers Website" aria-label="U.S. Healthcare Providers Website (opens in a new window)"> <span>U.S. Healthcare Providers Website</span> 590 </a> 591 </li> 592 </ul> 593 594 595 </div> 596 597 <div class="header-main-menu"> 598 599 600 601<nav class="navbar navbar-dark navbar-expand-md" aria-label="primary" id="primary"> 602 <div class="navbar__container container"> 603 <div class="navbar__logo"> 604 605 606<a 607 class="logo__link" 608 data-analytics-name="AbilifyAsimtufii Logo" 609 href="/" 610> 611 612 613 614<img 615 class="logo__image" 616 src="/sites/g/files/qhldwo13476/themes/site/themes/custom/otsuka_ds3_abilifyasimhcc/images/logos.svg" 617 alt="ABILIFY ASIMTUFII logo and ABILIFY MAINTENA logo" 618 /> 619 </a> 620 </div> 621 622 623 <div class="navbar bp-menu"> 624 625 626 627 628 629 630 631 632<ul class="main-menu-bs main-menu-bs-- navbar-nav ms-auto list-unstyled"> 633 634 635 636 637<li class="main-menu-bs__item nav-item" > 638 639 640 641 642 643 644 <a href="/bipolar-I" target="_self" class="d-none main-menu-bs-link nav-link" data-item-title="Homepage" data-drupal-link-system-path="node/166">
644 <span>Homepage</span> 645 </a> 646 </li> 647 648 649 650<li class="main-menu-bs__item nav-item" > 651 652 653 654 655 656 657 <a href="/bipolar-I/long-acting-injectables" target="_self" class="main-menu-bs-link nav-link" data-item-title="About LAIs" data-drupal-link-system-path="node/171"> <span>About LAIs</span> 658 </a> 659 </li> 660 661 662 663<li class="main-menu-bs__item nav-item" > 664 665 666 667 668 669 670 <a href="/bipolar-I/study-results" target="_self" class="main-menu-bs-link nav-link" data-item-title="Study Results" data-drupal-link-system-path="node/351"> <span>Study Results</span> 671 </a> 672 </li> 673 674 675 676<li class="main-menu-bs__item nav-item" > 677 678 679 680 681 682 683 <a href="/bipolar-I/side-effects" target="_self" class="main-menu-bs-link nav-link" data-item-title="Side Effects" data-drupal-link-system-path="node/181"> <span>Side Effects</span> 684 </a> 685 </li> 686 687 688 689<li class="main-menu-bs__item main-menu-bs__item--with-sub main-menu-bs__item--dropdown nav-item dropdown" > 690 691 692 693 694 695 696 <button target="_self" class="main-menu-bs-link dropdown-toggle nav-link" data-bs-toggle="dropdown" data-item-title="Getting Started" type="button"> <span>Getting Started</span> 697 </button> 698 699 700 701 702<ul class="main-menu-bs main-menu-bs--sub main-menu-bs--sub-1 dropdown-menu list-unstyled"> 703 704 705 706 707<li class="main-menu-bs__item main-menu-bs__item--sub main-menu-bs__item--sub-1 nav-item dropdown" > 708 709 710 711 712 713 714 <a href="/bipolar-I/talking-to-your-doctor" target="_self" class="main-menu-bs-link dropdown-item" data-item-title="Talking to your doctor" data-drupal-link-system-path="node/186"> <span>Talking to your doctor</span> 715 </a> 716 </li> 717 718 719 720<li class="main-menu-bs__item main-menu-bs__item--sub main-menu-bs__item--sub-1 nav-item dropdown" > 721 722 723 724 725 726 727 <a href="/bipolar-I/what-to-expect" target="_self" class="main-menu-bs-link dropdown-item" data-item-title="What to expect with these injections" data-drupal-link-system-path="node/191"> <span>What to expect with these injections</span> 728 </a> 729 </li> 730 731 732 733<li class="main-menu-bs__item main-menu-bs__item--sub main-menu-bs__item--sub-1 nav-item dropdown" > 734 735 736 737 738 739 740 <a href="/bipolar-I/long-acting-injectables-transition" target="_self" class="main-menu-bs-link dropdown-item" data-item-title="Transitioning to these&nbsp;LAIs" data-drupal-link-system-path="node/316"> <span>Transitioning to these LAIs</span> 741 </a> 742 </li> 743 744 745 746<li class="main-menu-bs__item main-menu-bs__item--sub main-menu-bs__item--sub-1 nav-item dropdown" > 747 748 749 750 751 752 753 <a href="/bipolar-I/staying-on-track-with-treatment" target="_self" class="main-menu-bs-link dropdown-item" data-item-title="Staying on track" data-drupal-link-system-path="node/321"> <span>Staying on track</span> 754 </a> 755 </li> 756 </ul> 757 758 </li> 759 760 761 762<li class="main-menu-bs__item nav-item" > 763 764 765 766 767 768 769 <a href="/bipolar-I/cost-savings" target="_self" class="main-menu-bs-link nav-link" data-item-title="Cost & Savings" data-drupal-link-system-path="node/196"> <span>Cost & Savings</span> 770 </a> 771 </li> 772 773 774 775<li class="main-menu-bs__item main-menu-bs__item--with-sub main-menu-bs__item--dropdown nav-item dropdown" > 776 777 778 779 780 781 782 <button target="_self" class="main-menu-bs-link dropdown-toggle nav-link" data-bs-toggle="dropdown" data-item-title="FAQs & Resources" type="button">
782 <span>FAQs & Resources</span> 783 </button> 784 785 786 787 788<ul class="main-menu-bs main-menu-bs--sub main-menu-bs--sub-1 dropdown-menu list-unstyled"> 789 790 791 792 793<li class="main-menu-bs__item main-menu-bs__item--sub main-menu-bs__item--sub-1 nav-item dropdown" > 794 795 796 797 798 799 800 <a href="/bipolar-I/common-questions" target="_self" class="main-menu-bs-link dropdown-item" data-item-title="FAQs" data-drupal-link-system-path="node/221"> <span>FAQs</span> 801 </a> 802 </li> 803 804 805 806<li class="main-menu-bs__item main-menu-bs__item--sub main-menu-bs__item--sub-1 nav-item dropdown" > 807 808 809 810 811 812 813 <a href="/bipolar-I/tools-resources" target="_self" class="main-menu-bs-link dropdown-item" data-item-title="Resources" data-drupal-link-system-path="node/206"> <span>Resources</span> 814 </a> 815 </li> 816 817 818 819<li class="main-menu-bs__item main-menu-bs__item--sub main-menu-bs__item--sub-1 nav-item dropdown" > 820 821 822 823 824 825 826 <a href="/bipolar-I/community-support" target="_self" class="main-menu-bs-link dropdown-item" data-item-title="Community support" data-drupal-link-system-path="node/201"> <span>Community support</span> 827 </a> 828 </li> 829 </ul> 830 831 </li> 832 </ul> 833 834 835 </div> 836 <div class="navbar sz-menu d-none"> 837 838 839 840 841 842 843 844 845<ul class="main-menu-bs main-menu-bs-- navbar-nav ms-auto list-unstyled"> 846 847 848 849 850<li class="main-menu-bs__item nav-item" > 851 852 853 854 855 856 857 <a href="/schizophrenia" target="_self" class="d-none main-menu-bs-link nav-link" data-item-title="Homepage" data-drupal-link-system-path="node/226"> <span>Homepage</span> 858 </a> 859 </li> 860 861 862 863<li class="main-menu-bs__item nav-item" > 864 865 866 867 868 869 870 <a href="/schizophrenia/long-acting-injectables" target="_self" class="main-menu-bs-link nav-link" data-item-title="About LAIs" data-drupal-link-system-path="node/231"> <span>About LAIs</span> 871 </a> 872 </li> 873 874 875 876<li class="main-menu-bs__item nav-item" > 877 878 879 880 881 882 883 <a href="/schizophrenia/study-results" target="_self" class="main-menu-bs-link nav-link" data-item-title="Study Results" data-drupal-link-system-path="node/346"> <span>Study Results</span> 884 </a> 885 </li> 886 887 888 889<li class="main-menu-bs__item nav-item" > 890 891 892 893 894 895 896 <a href="/schizophrenia/side-effects" target="_self" class="main-menu-bs-link nav-link" data-item-title="Side Effects" data-drupal-link-system-path="node/241"> <span>Side Effects</span> 897 </a> 898 </li> 899 900 901 902<li class="main-menu-bs__item main-menu-bs__item--with-sub main-menu-bs__item--dropdown nav-item dropdown" > 903 904 905 906 907 908 909 <button target="_self" class="dropdown-1 main-menu-bs-link dropdown-toggle nav-link" data-bs-toggle="dropdown" data-item-title="Getting Started" type="button"> <span>Getting Started</span> 910 </button> 911 912 913 914 915<ul class="main-menu-bs main-menu-bs--sub main-menu-bs--sub-1 dropdown-menu list-unstyled"> 916 917 918 919 920<li class="main-menu-bs__item main-menu-bs__item--sub main-menu-bs__item--sub-1 nav-item dropdown" > 921 922 923 924 925 926 927 <a href="/schizophrenia/talking-to-your-doctor" target="_self" class="main-menu-bs-link dropdown-item" data-item-title="Talking to your doctor" data-drupal-link-system-path="node/246">
927 <span>Talking to your doctor</span> 928 </a> 929 </li> 930 931 932 933<li class="main-menu-bs__item main-menu-bs__item--sub main-menu-bs__item--sub-1 nav-item dropdown" > 934 935 936 937 938 939 940 <a href="/schizophrenia/what-to-expect" target="_self" class="main-menu-bs-link dropdown-item" data-item-title="What to expect with these injections" data-drupal-link-system-path="node/251"> <span>What to expect with these injections</span> 941 </a> 942 </li> 943 944 945 946<li class="main-menu-bs__item main-menu-bs__item--sub main-menu-bs__item--sub-1 nav-item dropdown" > 947 948 949 950 951 952 953 <a href="/schizophrenia/long-acting-injectables-transition" target="_self" class="main-menu-bs-link dropdown-item" data-item-title="Transitioning to these&nbsp;LAIs" data-drupal-link-system-path="node/326"> <span>Transitioning to these LAIs</span> 954 </a> 955 </li> 956 957 958 959<li class="main-menu-bs__item main-menu-bs__item--sub main-menu-bs__item--sub-1 nav-item dropdown" > 960 961 962 963 964 965 966 <a href="/schizophrenia/staying-on-track-with-treatment" target="_self" class="main-menu-bs-link dropdown-item" data-item-title="Staying on track" data-drupal-link-system-path="node/331"> <span>Staying on track</span> 967 </a> 968 </li> 969 </ul> 970 971 </li> 972 973 974 975<li class="main-menu-bs__item nav-item" > 976 977 978 979 980 981 982 <a href="/schizophrenia/cost-savings" target="_self" class="main-menu-bs-link nav-link" data-item-title="Cost & Savings" data-drupal-link-system-path="node/256"> <span>Cost & Savings</span> 983 </a> 984 </li> 985 986 987 988<li class="main-menu-bs__item main-menu-bs__item--with-sub main-menu-bs__item--dropdown nav-item dropdown" > 989 990 991 992 993 994 995 <button target="_self" class="dropdown-2 main-menu-bs-link dropdown-toggle nav-link" data-bs-toggle="dropdown" data-item-title="FAQs & Resources" type="button"> <span>FAQs & Resources</span> 996 </button> 997 998 999 1000 1001<ul class="main-menu-bs main-menu-bs--sub main-menu-bs--sub-1 dropdown-menu list-unstyled"> 1002 1003 1004 1005 1006<li class="main-menu-bs__item main-menu-bs__item--sub main-menu-bs__item--sub-1 nav-item dropdown" > 1007 1008 1009 1010 1011 1012 1013 <a href="/schizophrenia/common-questions" target="_self" class="main-menu-bs-link dropdown-item" data-item-title="FAQs" data-drupal-link-system-path="node/281"> <span>FAQs</span> 1014 </a> 1015 </li> 1016 1017 1018 1019<li class="main-menu-bs__item main-menu-bs__item--sub main-menu-bs__item--sub-1 nav-item dropdown" > 1020 1021 1022 1023 1024 1025 1026 <a href="/schizophrenia/tools-resources" target="_self" class="main-menu-bs-link dropdown-item" data-item-title="Resources" data-drupal-link-system-path="node/271"> <span>Resources</span> 1027 </a> 1028 </li> 1029 1030 1031 1032<li class="main-menu-bs__item main-menu-bs__item--sub main-menu-bs__item--sub-1 nav-item dropdown" > 1033 1034 1035 1036 1037 1038 1039 <a href="/schizophrenia/caregiver-support" target="_self" class="main-menu-bs-link dropdown-item" data-item-title="Support for caregivers" data-drupal-link-system-path="node/261"> <span>Support for caregivers</span> 1040 </a> 1041 </li> 1042 1043 1044 1045<li class="main-menu-bs__item main-menu-bs__item--sub main-menu-bs__item--sub-1 nav-item dropdown" > 1046 1047 1048 1049 1050 1051 1052 <a href="/schizophrenia/community-support" target="_self" class="main-menu-bs-link dropdown-item" data-item-title="Community support" data-drupal-link-system-path="node/266">
1052 <span>Community support</span> 1053 </a> 1054 </li> 1055 </ul> 1056 1057 </li> 1058 </ul> 1059 1060 1061 </div> 1062 1063 1064 </div> 1065</nav> 1066 1067 </div> 1068 1069 1070 1071 1072 1073 1074 1075 1076<button class="btn btn-primary btn-md navbar-toggler" type="button" data-bs-toggle="collapse" data-bs-target="#navbar_collapse-primary" aria-expanded="false" aria-label="Toggle navigation" aria-controls="navbar_collapse-primary" data-analytics-name="Toggle mobile navigation" data-test="mobile-menu-toggle" > 1077 <span class="navbar-toggler-icon"></span> 1078 1079 </button> 1080 1081 <div class="header-main-mobile__collapse collapse navbar-collapse" 1082 id="navbar_collapse-primary"> 1083 1084 1085 1086<nav class="navbar navbar-dark navbar-expand-md" aria-label="primary" id="primary"> 1087 <div class="navbar__container container"> 1088 1089 1090 1091 1092 1093 1094 1095 1096 1097<ul class="site-switcher site-switcher-- list-unstyled"> 1098 1099 1100 1101 1102<li class="site-switcher__item site-switcher__item--with-sub site-switcher__item--dropdown nav-item dropdown" > 1103 1104 1105 1106 1107 1108 1109 <button target="_self" class="site-switcher-link dropdown-toggle nav-link" data-bs-toggle="dropdown" data-item-title="Bipolar I Disorder" type="button"> <span>Bipolar I Disorder</span> 1110 </button> 1111 1112 1113 1114 1115<ul class="site-switcher site-switcher--sub site-switcher--sub-1 dropdown-menu list-unstyled"> 1116 1117 1118 1119 1120<li class="site-switcher__item site-switcher__item--sub site-switcher__item--sub-1 nav-item dropdown" > 1121 1122 1123 1124 1125 1126 1127 <a href="/bipolar-I" target="_self" class="site-switcher-link dropdown-item" data-item-title="Bipolar I Disorder" data-drupal-link-system-path="node/166"> <span>Bipolar I Disorder</span> 1128 </a> 1129 </li> 1130 1131 1132 1133<li class="site-switcher__item site-switcher__item--sub site-switcher__item--sub-1 nav-item dropdown" > 1134 1135 1136 1137 1138 1139 1140 <a href="/schizophrenia" target="_self" class="site-switcher-link dropdown-item" data-item-title="Schizophrenia" data-drupal-link-system-path="node/226"> <span>Schizophrenia</span> 1141 </a> 1142 </li> 1143 </ul> 1144 1145 </li> 1146 </ul> 1147 1148 1149 1150 <div class="navbar bp-menu"> 1151 1152 1153 1154 1155 1156 1157 1158 1159<ul class="main-menu-bs main-menu-bs-- navbar-nav ms-auto list-unstyled"> 1160 1161 1162 1163 1164<li class="main-menu-bs__item nav-item" > 1165 1166 1167 1168 1169 1170 1171 <a href="/bipolar-I" target="_self" class="d-none main-menu-bs-link nav-link" data-item-title="Homepage" data-drupal-link-system-path="node/166"> <span>Homepage</span> 1172 </a> 1173 </li> 1174 1175 1176 1177<li class="main-menu-bs__item nav-item" > 1178 1179 1180 1181 1182 1183 1184 <a href="/bipolar-I/long-acting-injectables" target="_self" class="main-menu-bs-link nav-link" data-item-title="About LAIs" data-drupal-link-system-path="node/171"> <span>About LAIs</span> 1185 </a> 1186 </li> 1187 1188 1189 1190<li class="main-menu-bs__item nav-item" > 1191 1192 1193 1194 1195 1196 1197 <a href="/bipolar-I/study-results" target="_self" class="main-menu-bs-link nav-link" data-item-title="Study Results" data-drupal-link-system-path="node/351"> <span>Study Results</span> 1198 </a> 1199 </li> 1200 1201 1202 1203<li class="main-menu-bs__item nav-item" > 1204 1205 1206 1207 1208 1209 1210 <a href="/bipolar-I/side-effects" target="_self" class="main-menu-bs-link nav-link" data-item-title="Side Effects" data-drupal-link-system-path="node/181"> <span>Side Effects</span> 1211 </a> 1212 </li> 1213 1214 1215 1216<li class="main-menu-bs__item main-menu-bs__item--with-sub main-menu-bs__item--dropdown nav-item dropdown" > 1217 1218 1219 1220 1221 1222 1223 <button target="_self" class="main-menu-bs-link dropdown-toggle nav-link" data-bs-toggle="dropdown" data-item-title="Getting Started" type="button">
1223 <span>Getting Started</span> 1224 </button> 1225 1226 1227 1228 1229<ul class="main-menu-bs main-menu-bs--sub main-menu-bs--sub-1 dropdown-menu list-unstyled"> 1230 1231 1232 1233 1234<li class="main-menu-bs__item main-menu-bs__item--sub main-menu-bs__item--sub-1 nav-item dropdown" > 1235 1236 1237 1238 1239 1240 1241 <a href="/bipolar-I/talking-to-your-doctor" target="_self" class="main-menu-bs-link dropdown-item" data-item-title="Talking to your doctor" data-drupal-link-system-path="node/186"> <span>Talking to your doctor</span> 1242 </a> 1243 </li> 1244 1245 1246 1247<li class="main-menu-bs__item main-menu-bs__item--sub main-menu-bs__item--sub-1 nav-item dropdown" > 1248 1249 1250 1251 1252 1253 1254 <a href="/bipolar-I/what-to-expect" target="_self" class="main-menu-bs-link dropdown-item" data-item-title="What to expect with these injections" data-drupal-link-system-path="node/191"> <span>What to expect with these injections</span> 1255 </a> 1256 </li> 1257 1258 1259 1260<li class="main-menu-bs__item main-menu-bs__item--sub main-menu-bs__item--sub-1 nav-item dropdown" > 1261 1262 1263 1264 1265 1266 1267 <a href="/bipolar-I/long-acting-injectables-transition" target="_self" class="main-menu-bs-link dropdown-item" data-item-title="Transitioning to these&nbsp;LAIs" data-drupal-link-system-path="node/316"> <span>Transitioning to these LAIs</span> 1268 </a> 1269 </li> 1270 1271 1272 1273<li class="main-menu-bs__item main-menu-bs__item--sub main-menu-bs__item--sub-1 nav-item dropdown" > 1274 1275 1276 1277 1278 1279 1280 <a href="/bipolar-I/staying-on-track-with-treatment" target="_self" class="main-menu-bs-link dropdown-item" data-item-title="Staying on track" data-drupal-link-system-path="node/321"> <span>Staying on track</span> 1281 </a> 1282 </li> 1283 </ul> 1284 1285 </li> 1286 1287 1288 1289<li class="main-menu-bs__item nav-item" > 1290 1291 1292 1293 1294 1295 1296 <a href="/bipolar-I/cost-savings" target="_self" class="main-menu-bs-link nav-link" data-item-title="Cost & Savings" data-drupal-link-system-path="node/196"> <span>Cost & Savings</span> 1297 </a> 1298 </li> 1299 1300 1301 1302<li class="main-menu-bs__item main-menu-bs__item--with-sub main-menu-bs__item--dropdown nav-item dropdown" > 1303 1304 1305 1306 1307 1308 1309 <button target="_self" class="main-menu-bs-link dropdown-toggle nav-link" data-bs-toggle="dropdown" data-item-title="FAQs & Resources" type="button"> <span>FAQs & Resources</span> 1310 </button> 1311 1312 1313 1314 1315<ul class="main-menu-bs main-menu-bs--sub main-menu-bs--sub-1 dropdown-menu list-unstyled"> 1316 1317 1318 1319 1320<li class="main-menu-bs__item main-menu-bs__item--sub main-menu-bs__item--sub-1 nav-item dropdown" > 1321 1322 1323 1324 1325 1326 1327 <a href="/bipolar-I/common-questions" target="_self" class="main-menu-bs-link dropdown-item" data-item-title="FAQs" data-drupal-link-system-path="node/221"> <span>FAQs</span> 1328 </a> 1329 </li> 1330 1331 1332 1333<li class="main-menu-bs__item main-menu-bs__item--sub main-menu-bs__item--sub-1 nav-item dropdown" > 1334 1335 1336 1337 1338 1339 1340 <a href="/bipolar-I/tools-resources" target="_self" class="main-menu-bs-link dropdown-item" data-item-title="Resources" data-drupal-link-system-path="node/206"> <span>Resources</span> 1341 </a> 1342 </li> 1343 1344 1345 1346<li class="main-menu-bs__item main-menu-bs__item--sub main-menu-bs__item--sub-1 nav-item dropdown" > 1347 1348 1349 1350 1351 1352 1353 <a href="/bipolar-I/community-support" target="_self" class="main-menu-bs-link dropdown-item" data-item-title="Community support" data-drupal-link-system-path="node/201">
1353 <span>Community support</span> 1354 </a> 1355 </li> 1356 </ul> 1357 1358 </li> 1359 </ul> 1360 1361 1362 </div> 1363 <div class="navbar sz-menu d-none"> 1364 1365 1366 1367 1368 1369 1370 1371 1372<ul class="main-menu-bs main-menu-bs-- navbar-nav ms-auto list-unstyled"> 1373 1374 1375 1376 1377<li class="main-menu-bs__item nav-item" > 1378 1379 1380 1381 1382 1383 1384 <a href="/schizophrenia" target="_self" class="d-none main-menu-bs-link nav-link" data-item-title="Homepage" data-drupal-link-system-path="node/226"> <span>Homepage</span> 1385 </a> 1386 </li> 1387 1388 1389 1390<li class="main-menu-bs__item nav-item" > 1391 1392 1393 1394 1395 1396 1397 <a href="/schizophrenia/long-acting-injectables" target="_self" class="main-menu-bs-link nav-link" data-item-title="About LAIs" data-drupal-link-system-path="node/231"> <span>About LAIs</span> 1398 </a> 1399 </li> 1400 1401 1402 1403<li class="main-menu-bs__item nav-item" > 1404 1405 1406 1407 1408 1409 1410 <a href="/schizophrenia/study-results" target="_self" class="main-menu-bs-link nav-link" data-item-title="Study Results" data-drupal-link-system-path="node/346"> <span>Study Results</span> 1411 </a> 1412 </li> 1413 1414 1415 1416<li class="main-menu-bs__item nav-item" > 1417 1418 1419 1420 1421 1422 1423 <a href="/schizophrenia/side-effects" target="_self" class="main-menu-bs-link nav-link" data-item-title="Side Effects" data-drupal-link-system-path="node/241"> <span>Side Effects</span> 1424 </a> 1425 </li> 1426 1427 1428 1429<li class="main-menu-bs__item main-menu-bs__item--with-sub main-menu-bs__item--dropdown nav-item dropdown" > 1430 1431 1432 1433 1434 1435 1436 <button target="_self" class="dropdown-1 main-menu-bs-link dropdown-toggle nav-link" data-bs-toggle="dropdown" data-item-title="Getting Started" type="button"> <span>Getting Started</span> 1437 </button> 1438 1439 1440 1441 1442<ul class="main-menu-bs main-menu-bs--sub main-menu-bs--sub-1 dropdown-menu list-unstyled"> 1443 1444 1445 1446 1447<li class="main-menu-bs__item main-menu-bs__item--sub main-menu-bs__item--sub-1 nav-item dropdown" > 1448 1449 1450 1451 1452 1453 1454 <a href="/schizophrenia/talking-to-your-doctor" target="_self" class="main-menu-bs-link dropdown-item" data-item-title="Talking to your doctor" data-drupal-link-system-path="node/246"> <span>Talking to your doctor</span> 1455 </a> 1456 </li> 1457 1458 1459 1460<li class="main-menu-bs__item main-menu-bs__item--sub main-menu-bs__item--sub-1 nav-item dropdown" > 1461 1462 1463 1464 1465 1466 1467 <a href="/schizophrenia/what-to-expect" target="_self" class="main-menu-bs-link dropdown-item" data-item-title="What to expect with these injections" data-drupal-link-system-path="node/251"> <span>What to expect with these injections</span> 1468 </a> 1469 </li> 1470 1471 1472 1473<li class="main-menu-bs__item main-menu-bs__item--sub main-menu-bs__item--sub-1 nav-item dropdown" > 1474 1475 1476 1477 1478 1479 1480 <a href="/schizophrenia/long-acting-injectables-transition" target="_self" class="main-menu-bs-link dropdown-item" data-item-title="Transitioning to these&nbsp;LAIs" data-drupal-link-system-path="node/326"> <span>Transitioning to these LAIs</span> 1481 </a> 1482 </li> 1483 1484 1485 1486<li class="main-menu-bs__item main-menu-bs__item--sub main-menu-bs__item--sub-1 nav-item dropdown" > 1487 1488 1489 1490 1491 1492 1493 <a href="/schizophrenia/staying-on-track-with-treatment" target="_self" class="main-menu-bs-link dropdown-item" data-item-title="Staying on track" data-drupal-link-system-path="node/331">
1493 <span>Staying on track</span> 1494 </a> 1495 </li> 1496 </ul> 1497 1498 </li> 1499 1500 1501 1502<li class="main-menu-bs__item nav-item" > 1503 1504 1505 1506 1507 1508 1509 <a href="/schizophrenia/cost-savings" target="_self" class="main-menu-bs-link nav-link" data-item-title="Cost & Savings" data-drupal-link-system-path="node/256"> <span>Cost & Savings</span> 1510 </a> 1511 </li> 1512 1513 1514 1515<li class="main-menu-bs__item main-menu-bs__item--with-sub main-menu-bs__item--dropdown nav-item dropdown" > 1516 1517 1518 1519 1520 1521 1522 <button target="_self" class="dropdown-2 main-menu-bs-link dropdown-toggle nav-link" data-bs-toggle="dropdown" data-item-title="FAQs & Resources" type="button"> <span>FAQs & Resources</span> 1523 </button> 1524 1525 1526 1527 1528<ul class="main-menu-bs main-menu-bs--sub main-menu-bs--sub-1 dropdown-menu list-unstyled"> 1529 1530 1531 1532 1533<li class="main-menu-bs__item main-menu-bs__item--sub main-menu-bs__item--sub-1 nav-item dropdown" > 1534 1535 1536 1537 1538 1539 1540 <a href="/schizophrenia/common-questions" target="_self" class="main-menu-bs-link dropdown-item" data-item-title="FAQs" data-drupal-link-system-path="node/281"> <span>FAQs</span> 1541 </a> 1542 </li> 1543 1544 1545 1546<li class="main-menu-bs__item main-menu-bs__item--sub main-menu-bs__item--sub-1 nav-item dropdown" > 1547 1548 1549 1550 1551 1552 1553 <a href="/schizophrenia/tools-resources" target="_self" class="main-menu-bs-link dropdown-item" data-item-title="Resources" data-drupal-link-system-path="node/271"> <span>Resources</span> 1554 </a> 1555 </li> 1556 1557 1558 1559<li class="main-menu-bs__item main-menu-bs__item--sub main-menu-bs__item--sub-1 nav-item dropdown" > 1560 1561 1562 1563 1564 1565 1566 <a href="/schizophrenia/caregiver-support" target="_self" class="main-menu-bs-link dropdown-item" data-item-title="Support for caregivers" data-drupal-link-system-path="node/261"> <span>Support for caregivers</span> 1567 </a> 1568 </li> 1569 1570 1571 1572<li class="main-menu-bs__item main-menu-bs__item--sub main-menu-bs__item--sub-1 nav-item dropdown" > 1573 1574 1575 1576 1577 1578 1579 <a href="/schizophrenia/community-support" target="_self" class="main-menu-bs-link dropdown-item" data-item-title="Community support" data-drupal-link-system-path="node/266"> <span>Community support</span> 1580 </a> 1581 </li> 1582 </ul> 1583 1584 </li> 1585 </ul> 1586 1587 1588 </div> 1589 1590 1591 1592 1593<a 1594 class="navbar__cta btn" 1595 href="/important-safety-information" 1596 > 1597 <span class="text">Important Safety Information</span> 1598 </a> 1599 1600 1601 1602 1603 1604 1605 1606 1607 1608<ul class="top-menu top-menu-- d-inline-flex list-unstyled"> 1609 1610 1611 1612 1613<li class="top-menu__item nav-item" > 1614 1615 1616 1617 1618 1619 1620 <a href="https://abilifyasimtufiihcp.com/" target="_blank" class="desktop-only top-menu-link nav-link" data-item-title="U.S. Healthcare Providers Website" aria-label="U.S. Healthcare Providers Website (opens in a new window)"> <span>U.S. Healthcare Providers Website</span> 1621 </a> 1622 </li> 1623 </ul> 1624 1625 1626 </div> 1627</nav> 1628 1629 </div> 1630 1631</header> 1632 1633 1634 1635 1636 1637 1638 1639 1640 1641 <div class="main"> 1642 <div id="main-content"></div> <main role="main" class="main-content"> 1643 1644 1645 1646 1647 1648<div id="block-block-otsuka-ds3-abilifyasimhcc-content" id="block-otsuka-ds3-abilifyasimhcc-content" class="system"> 1649 1650 1651 1652<article class="node"> 1653 1654 1655 1656 1657 1658 <div> 1659 1660 1661 1662 1663 1664 1665 1666 1667 1668 1669 1670 1671 1672 1673 1674<div class="monthly-option overflow-hidden" id="paragraph-9081" data-test='paragraph' > 1675 <div class="monthly-option__wrapper container-xl"> 1676 1677 1678 1679 1680 1681<div class="text-block" > 1682 <div> 1683 1684 1685 1686<h1 class="text-block text-block--title"> 1687 Could a long-acting treatment be your next step? 1688 </h1> 1689 1690 </div> 1691 1692 <span class="accent-bar"></span> 1693 1694 </div> 1695 <div class="monthly-option__cards_wrapper"> 1696 1697 1698 1699<h3 class="heading text-center"> 1700 Choose a condition to explore treatment information. 1701 </h3> 1702 <div class="monthly-option__cards"> 1703 1704 1705<div class="card-s__wrapper section--bipolar-i" data-test='card'> 1706 <div class="card-s__background d-block d-sm-none"> 1707 1708 1709 1710<img 1711 class="card-s__image" 1712 src="/sites/g/files/qhldwo13476/files/2025-11/BP-Emma_Reading_mob.jpg" 1713 alt="ABILIFY ASIMTUFII for bipolar disorder patient Emma reading a book." 1714 /> 1715 </div> 1716 <div class="card-s__background d-none d-sm-block"> 1717 1718 1719 1720<img 1721 class="card-s__image" 1722 src="/sites/g/files/qhldwo13476/files/2025-11/BP-Emma_Reading.jpg" 1723 alt="ABILIFY ASIMTUFII for bipolar disorder patient Emma reading a book." 1724 /> 1725 </div> 1726 <div class="card-s__link"> 1727 1728 1729<a 1730 class="link__cta link__cta--primary btn" 1731 target="_self" 1732 class="" 1733 href="/bipolar-I" 1734 >
1735 <span class="text">Bipolar I Disorder</span> 1736 </a> 1737 </div> 1738 </div> 1739 1740 1741<div class="card-s__wrapper section--schizophrenia" data-test='card'> 1742 <div class="card-s__background d-block d-sm-none"> 1743 1744 1745 1746<img 1747 class="card-s__image" 1748 src="/sites/g/files/qhldwo13476/files/2025-11/SZ-Luke_Guitar_mob.jpg" 1749 alt="SZ: Luke Guitar" 1750 /> 1751 </div> 1752 <div class="card-s__background d-none d-sm-block"> 1753 1754 1755 1756<img 1757 class="card-s__image" 1758 src="/sites/g/files/qhldwo13476/files/2025-11/SZ-Luke_Guitar.jpg" 1759 alt="ABILIFY ASIMTUFII for schizophrenia patient Luke playing the guitar." 1760 /> 1761 </div> 1762 <div class="card-s__link"> 1763 1764 1765<a 1766 class="link__cta link__cta--primary btn" 1767 target="_self" 1768 class="" 1769 href="/schizophrenia" 1770 > 1771 <span class="text">Schizophrenia</span> 1772 </a> 1773 </div> 1774 </div> 1775 </div> 1776 </div> 1777 <div class="monthly-option__headlines"> 1778 <div class="monthly-option__headline"> 1779 <div class="monthly-option__headline_title"> 1780 1781 1782 1783<h3 class="heading mb-0"> 1784 ABILIFY ASIMTUFII<sup class="rball">®</sup> (aripiprazole) 1785 </h3> 1786 </div> 1787 <div class="monthly-option__headline_text"> 1788 <p>Once every-2-months* maintenance treatment for bipolar I disorder and treatment for schizophrenia in adults.</p> 1789 </div> 1790 </div> 1791 <div class="monthly-option__headline"> 1792 <div class="monthly-option__headline_title"> 1793 1794 1795 1796<h3 class="heading mb-0"> 1797 ABILIFY MAINTENA<sup class="rball">®</sup> (aripiprazole) 1798 </h3> 1799 </div> 1800 <div class="monthly-option__headline_text"> 1801 <p>Once-monthly* maintenance treatment for bipolar I disorder and treatment for schizophrenia in adults.</p> 1802 </div> 1803 </div> 1804 </div> 1805 1806<div 1807 class="monthly-option__footnote footnote mb-0" 1808 > 1809 <p class="ms-7 mb-0"><span class="external">*</span>Work with your healthcare provider to make sure you can tolerate aripiprazole prior to starting treatment.</p> 1810 </div> 1811 </div> 1812 </div> 1813 1814 1815 1816 1817 1818 </div> 1819 1820</article> 1821 1822 </div> 1823 1824 1825 1826<a id="isi-top" name="isi-top" data-analytics-link='{"name":"isi_top","position":"footer","group":"isi","href":"n/a"}'></a> 1827<section aria-labelledby="isi-block-title" id="inline-isi-wrapper" class="section isi-section" data-analytics-group="ISI" data-test='isi'> 1828 1829 <div class="isi isi-block"> 1830 <div class="isi-inline-title-wrap"><h3 id="isi-block-title" class="isi-block-title"> IMPORTANT SAFETY INFORMATION and INDICATIONS 1831</h3></div> 1832 1833 <div class="isi-inline-inner-wrap"> <div class="tabs tabs--general" data-test="tabs"> 1834 <div class="container-lg"> 1835 <div class="row"> 1836 <div class="col-60 col-tabs d-block"> 1837 <ul class="nav nav nav-tabs" id="ISITabsDesktop" role="tablist" data-test="tabs-titles"> 1838 <li class="nav__item nav-item"> 1839 <button class="nav__btn nav__btn--active btn-none btn-md nav-link active" id="ISITabsDesktop_0-tab" data-bs-toggle="tab" data-bs-target="#ISITabsDesktop_0" type="button" role="tab" aria-controls="ISITabsDesktop_0" aria-selected="false" data-test="tabs-item"> 1840 ABILIFY ASIMTUFII<sup class="rball">®</sup> (aripiprazole) and ABILIFY MAINTENA<sup class="rball">®</sup> (aripiprazole) 1841 </button> 1842 </li> 1843 <li class="nav__item nav-item"> 1844 <button class="nav__btn btn-none btn-md nav-link" id="ISITabsDesktop_1-tab" data-bs-toggle="tab" data-bs-target="#ISITabsDesktop_1" type="button" role="tab" aria-controls="ISITabsDesktop_1" aria-selected="false" data-test="tabs-item"> 1845 ABILIFY<sup class="rball">®</sup> (aripiprazole) 1846 </button> 1847 </li> 1848 </ul> 1849 <div class="tab-content" id="ISITabsDesktop_Content"> 1850 <div class="tab-pane fade show active" id="ISITabsDesktop_0" data-test="tabs-content" role="tabpanel" aria-labelledby="ISITabsDesktop_0"> 1851 <div class="tab-pane__text"> 1852 <div class="isi-content-section"> 1853 <p class="isi-content-section-title d-block">IMPORTANT SAFETY INFORMATION:</p> 1854 1855 <p class="text-close"><strong>Increased risk of death in elderly people with dementia-related psychosis. </strong><strong>ABILIFY ASIMTUFII</strong><strong> and </strong><strong>ABILIFY MAINTENA</strong><strong> increase the risk of death in elderly people who have lost touch with reality (psychosis) due to confusion and memory loss (dementia). </strong><strong>ABILIFY ASIMTUFII</strong><strong> and </strong><strong>ABILIFY MAINTENA</strong><strong> are not for the treatment of people with dementia-related psychosis.</strong></p> 1856 1857 <p class="text-close"><strong>Do not receive ABILIFY ASIMTUFII or ABILIFY MAINTENA if you </strong>are allergic to aripiprazole or any of the ingredients in ABILIFY ASIMTUFII or ABILIFY MAINTENA.</p> 1858 1859 <p><strong>ABILIFY ASIMTUFII or ABILIFY MAINTENA may cause serious side effects, including:</strong></p> 1860 1861 <ul> 1862 <li><strong>Increased risk of stroke</strong> and ministroke has been reported in clinical studies with oral aripiprazole of elderly people with dementia-related psychosis and can lead to death.</li> 1863 <li><strong>Neuroleptic malignant syndrome (NMS), a serious condition that can lead to death.</strong> Call your healthcare provider or go to the nearest emergency room right away if you have some or all of the following signs and symptoms of NMS: high fever, confusion, changes in pulse, heart rate, and blood pressure, stiff muscles, and increased sweating.</li> 1864 <li><strong>Uncontrolled body movements (tardive dyskinesia).</strong> ABILIFY ASIMTUFII and ABILIFY MAINTENA may cause movements that you cannot control in your face, tongue, or other body parts. Tardive dyskinesia may not go away, even if you stop receiving ABILIFY ASIMTUFII or ABILIFY MAINTENA. Tardive dyskinesia may also start after you stop receiving ABILIFY ASIMTUFII or ABILIFY MAINTENA.</li> 1865 <li><strong>Problems with your metabolism such as:</strong> 1866 <ul> 1867 <li> 1868 <p><strong>High blood sugar (hyperglycemia) and diabetes:</strong> Increases in blood sugar can happen in some people who are treated with ABILIFY ASIMTUFII or ABILIFY MAINTENA. Extremely high blood sugar can lead to coma or death. If you have diabetes or risk factors for diabetes such as being overweight or a family history of diabetes, your healthcare provider should check your blood sugar before you start treatment with ABILIFY ASIMTUFII or ABILIFY MAINTENA, and during treatment.</p> 1869 </li> 1870 </ul> 1871 1872 <p class="left-indent"><strong>Call your healthcare provider if you have any of these symptoms of high blood sugar during treatment with ABILIFY ASIMTUFII or ABILIFY MAINTENA:</strong></p> 1873 </li> 1874 </ul> 1875 1876 <ul class="left-indent"> 1877 <li> 1878 <p>feel very thirsty</p> 1879 </li> 1880 <li> 1881 <p>need to urinate more than usual</p> 1882 </li> 1883 <li> 1884 <p>feel very hungry</p> 1885 </li> 1886 <li> 1887 <p>feel weak or tired</p> 1888 </li> 1889 <li> 1890 <p>feel sick to your stomach</p> 1891 </li> 1892 <li> 1893 <p>feel confused, or your breath smells fruity</p> 1894 </li> 1895 </ul> 1896 1897 <ul class="arrow-indent"> 1898 <li><strong>Increased fat levels (cholesterol and triglycerides) in your blood.</strong></li> 1899 <li><strong>Weight gain.</strong> You and your healthcare provider should check your weight regularly during treatment.</li> 1900 </ul> 1901 1902 <ul class="symptoms-extended"> 1903 <li><strong>Unusual and uncontrollable (compulsive) urges.</strong> Some people receiving ABILIFY ASIMTUFII or ABILIFY MAINTENA have had unusual strong urges to gamble and gambling that cannot be controlled (compulsive gambling). Other
1903compulsive urges include sexual urges, shopping, and eating or binge eating. If you or your family members notice that you are having unusual urges or behaviors, talk to your healthcare provider.</li> 1904 <li><strong>Decreased blood pressure (orthostatic hypotension).</strong> You may feel lightheaded or faint when you rise too quickly from a sitting or lying position.</li> 1905 <li><strong>Falls.</strong> ABILIFY ASIMTUFII and ABILIFY MAINTENA may make you sleepy or dizzy, may cause a decrease in your blood pressure when changing position (orthostatic hypotension), and can slow your thinking and motor skills, which may lead to falls that can cause fractures or other injuries.</li> 1906 <li><strong>Low white blood cell count.</strong> Your healthcare provider may do blood tests during the first few months of treatment.</li> 1907 <li><strong>Seizures (convulsions)</strong></li> 1908 <li><strong>Sleepiness, drowsiness, feeling tired, difficulty thinking and doing normal activities. Do not</strong> drive a car, operate machinery, or do other dangerous activities until you know how ABILIFY ASIMTUFII or ABILIFY MAINTENA affects you. ABILIFY ASIMTUFII or ABILIFY MAINTENA may make you feel drowsy and affect your judgement, thinking, or motor skills.</li> 1909 <li><strong>Problems controlling your body temperature so that you feel too warm. Do not</strong> become too hot or dehydrated during treatment with ABILIFY ASIMTUFII or ABILIFY MAINTENA. <strong>Do not</strong> exercise too much. In hot weather, stay inside in a cool place if possible. Stay out of the sun. <strong>Do not</strong> wear too much clothing or heavy clothing. Drink plenty of water.</li> 1910 <li><strong>Difficulty swallowing</strong> that can cause food or liquid to get into your lungs.</li> 1911 </ul> 1912 1913 <p class="text-high"><strong>Do not</strong> drink alcohol during treatment with ABILIFY ASIMTUFII or ABILIFY MAINTENA.</p> 1914 1915 <p class="text-high"><strong>Before receiving ABILIFY ASIMTUFII or ABILIFY MAINTENA, tell your healthcare provider about all your medical conditions, including if you:</strong></p> 1916 1917 <ul class="medical-conditions"> 1918 <li> 1919 <p>have never taken aripiprazole before</p> 1920 </li> 1921 <li> 1922 <p>have or had diabetes or high blood sugar or a family history of diabetes or high blood sugar</p> 1923 </li> 1924 <li> 1925 <p>have or had high levels of total cholesterol, LDL cholesterol, or triglycerides, or low levels of HDL cholesterol</p> 1926 </li> 1927 <li> 1928 <p>have or had low or high blood pressure</p> 1929 </li> 1930 <li> 1931 <p>have or had heart problems or a stroke</p> 1932 </li> 1933 <li> 1934 <p>have or had a low white blood cell count</p> 1935 </li> 1936 <li> 1937 <p>have or had seizures (convulsions)</p> 1938 </li> 1939 <li> 1940 <p>have problems that may affect you receiving an injection in your buttocks (ABILIFY ASIMTUFII and ABILIFY MAINTENA) or arm (ABILIFY MAINTENA)</p> 1941 </li> 1942 <li> 1943 <p>are pregnant or plan to become pregnant. ABILIFY ASIMTUFII or ABILIFY MAINTENA may harm your unborn baby. If you become pregnant during treatment with ABILIFY ASIMTUFII or ABILIFY MAINTENA, talk to your healthcare provider about the risk to your unborn baby and about registering with the National Pregnancy Registry for Atypical Antipsychotics. You can register by calling <a tabindex="-1" href="tel:18669612388">1-866-961-2388</a> or visit <a class="link" href="http://womensmentalhealth.org/clinical-and-research-programs/pregnancyregistry/" target="_blank">http://womensmentalhealth.org/clinical-and-research-programs/pregnancyregistry/</a></p> 1944 </li> 1945 <li> 1946 <p>are breastfeeding or plan to breastfeed. ABILIFY ASIMTUFII or ABILIFY MAINTENA can pass into your milk and may harm your baby. Talk to your healthcare provider about the best way to feed your baby if you receive ABILIFY ASIMTUFII or ABILIFY MAINTENA.</p> 1947 </li> 1948 </ul> 1949 1950 <p><strong>Tell your healthcare provider about all the medicines you take,</strong> including prescription medicines and over-the-counter medicines, vitamins, and herbal supplements.</p> 1951 1952 <p>ABILIFY ASIMTUFII or ABILIFY MAINTENA and other medicines may affect each other, causing possible serious side effects. Do not start or stop any medicines during treatment with ABILIFY ASIMTUFII or ABILIFY MAINTENA without talking to your healthcare provider first.</p> 1953 1954 <p><strong>The most common side effects of ABILIFY ASIMTUFII or ABILIFY MAINTENA include:</strong> weight gain, restlessness or feeling like you need to move (akathisia), injection site pain, or sleepiness (sedation).</p> 1955 1956 <p>It is important to contact your healthcare provider if you experience prolonged, abnormal muscle spasms or contractions, which may be signs of a condition called dystonia.</p> 1957 1958 <p>These are not all the possible side effects of ABILIFY ASIMTUFII or ABILIFY MAINTENA.</p> 1959 1960 <p><strong>If you have any questions about your health or medicines, talk to your healthcare provider.</strong></p> 1961 1962 <p>You are encouraged to report side effects of ABILIFY ASIMTUFII and ABILIFY MAINTENA. Please contact Otsuka America Pharmaceutical, Inc. at <a tabindex="-1" href="tel:1-800-438-9927">1-800-438-9927</a> or FDA at <a tabindex="-1" href="tel:1-800-FDA-1088">1-800-FDA-1088</a> (<a class="link" href="https://www.fda.gov/medwatch" target="_blank">www.fda.gov/medwatch</a>).</p> 1963 </div> 1964 1965 <div class="isi-content-section"> 1966 <p class="isi-content-section-title">INDICATIONS:</p> 1967 <p>ABILIFY ASIMTUFII is a prescription medicine given by injection by a healthcare professional:</p> 1968 1969 <ul class="no-left-ident"> 1970 <li>for the treatment of schizophrenia in adults</li> 1971 <li>alone as maintenance treatment of bipolar I disorder in adults</li> 1972 </ul> 1973 1974 <p>ABILIFY MAINTENA is a prescription medicine given by injection by a healthcare professional:</p> 1975 1976 <ul class="mt-2"> 1977 <li>for the treatment of schizophrenia in adults</li> 1978 <li>alone as maintenance treatment of bipolar I disorder in adults</li> 1979 </ul> 1980 1981 <p>It is not known if ABILIFY ASIMTUFII or ABILIFY MAINTENA is safe and effective in children under 18 years of age.</p> 1982 <p>Please see FULL PRESCRIBING INFORMATION, including <strong>BOXED WARNING</strong>, for <a class="link external-link-popup-disabled" href="https://www.otsuka-u
1982s.com/media/static/Abilify-Asimtufii-PI.pdf" target="_blank">ABILIFY ASIMTUFII</a> and <a class="link external-link-popup-disabled" href="https://www.otsuka-us.com/media/static/Abilify-M-PI.pdf" target="_blank">ABILIFY MAINTENA</a>, and MEDICATION GUIDE for <a class="link external-link-popup-disabled" href="https://www.otsuka-us.com/media/static/Abilify-Asimtufii-MedGuide.pdf" target="_blank">ABILIFY ASIMTUFII</a> and <a class="link external-link-popup-disabled" href="https://www.otsuka-us.com/media/static/Abilify-M-Medguide.pdf" target="_blank">ABILIFY MAINTENA</a>.</p> 1983 </div> 1984 </div> 1985 </div> 1986 <div class="tab-pane fade " data-test="tabs-content" id="ISITabsDesktop_1" role="tabpanel" aria-labelledby="ISITabsDesktop_1"> 1987 <div class="tab-pane__text"> 1988 <div class="isi-content-section"> 1989 <p class="isi-content-section-title d-block">IMPORTANT SAFETY INFORMATION:</p> 1990 1991 <p class="text-close"><strong>Elderly people with psychosis related to dementia treated with antipsychotic medicines including ABILIFY, are at an increased risk of death compared to placebo. ABILIFY is not approved for the treatment of people with dementia-related psychosis.</strong></p> 1992 1993 <p class="text-close"><strong>Antidepressant medicines may increase suicidal thoughts or behaviors in some children, teenagers, and young adults, especially within the first few months of treatment or when the dose is changed.</strong></p> 1994<p class="text-close"><strong>Depression and other serious mental illnesses are themselves associated with an increase in the risk of suicide. Patients on antidepressants and their families or caregivers should watch for new or worsening depression symptoms, unusual changes in behavior, or thoughts of suicide. Such symptoms should be reported to the patient's healthcare provider right away, especially if they are severe or occur suddenly. ABILIFY is not approved for use in pediatric patients with depression.</strong></p> 1995 1996 <p class="text-close"><strong>Do not take ABILIFY if you </strong>are allergic to aripiprazole or any of the ingredients in ABILIFY. Allergic reactions have ranged from rash, hives, and itching to anaphylaxis, which may include difficulty breathing, tightness in the chest, and swelling of the mouth, face, lips, or tongue.</p> 1997 1998 <p><strong>ABILIFY may cause serious side effects, including:</strong></p> 1999 2000 <ul> 2001 <li><strong>Stroke in elderly people (cerebrovascular problems) that can lead to death</strong></li> 2002 <li><strong>Neuroleptic malignant syndrome (NMS).</strong> Tell your healthcare provider right away if you have some or all of the following symptoms: high fever, stiff muscles, confusion, sweating, changes in pulse, heart rate, and blood pressure. These may be symptoms of a rare and serious condition that can lead to death. Call your healthcare provider right away if you have any of these symptoms.</li> 2003 <li><strong>Uncontrolled body movements (tardive dyskinesia).</strong> ABILIFY may cause movements that you cannot control in your face, tongue, or other body parts. Tardive dyskinesia may not go away, even if you stop receiving ABILIFY. Tardive dyskinesia may also start after you stop receiving ABILIFY.</li> 2004 <li><strong>Problems with your metabolism such as:</strong> 2005 <ul> 2006 <li> 2007 <p><strong>High blood sugar (hyperglycemia) and diabetes.</strong> Increases in blood sugar can happen in some people who take ABILIFY. Extremely high blood sugar can lead to coma or death. If you have diabetes or risk factors for diabetes (such as being overweight or a family history of diabetes), your healthcare provider should check your blood sugar before you start ABILIFY and during your treatment.</p> 2008 </li> 2009 </ul> 2010 2011 <p class="left-indent"><strong>Call your healthcare provider if you have any of these symptoms of high blood sugar while receiving ABILIFY:</strong></p> 2012 </li> 2013 </ul> 2014 2015 <ul class="left-indent"> 2016 <li> 2017 <p>feel very thirsty</p> 2018 </li> 2019 <li> 2020 <p>need to urinate more than usual</p> 2021 </li> 2022 <li> 2023 <p>feel very hungry</p> 2024 </li> 2025 <li> 2026 <p>feel weak or tired</p> 2027 </li> 2028 <li> 2029 <p>feel sick to your stomach</p> 2030 </li> 2031 <li> 2032 <p>feel confused, or your breath smells fruity</p> 2033 </li> 2034 </ul> 2035 2036 <ul class="arrow-indent"> 2037 <li><strong>Increased fat levels (cholesterol and triglycerides) in your blood.</strong></li> 2038 <li><strong>Weight gain.</strong> You and your healthcare provider should check your weight regularly.</li> 2039 </ul> 2040 2041 <ul class="symptoms-extended"> 2042 <li><strong>Unusual urges.</strong> Some people taking ABILIFY have had unusual urges, such as gambling, binge eating or eating that you cannot control (compulsive), compulsive shopping and sexual urges. If you or your family members notice that you are having unusual urges or behaviors, talk to your healthcare provider.</li> 2043 <li><strong>Orthostatic hypotension (decreased blood pressure).</strong> Lightheadedness or fainting may happen when rising too quickly from a sitting or lying position.</li> 2044 <li><strong>Falls.</strong>
2044 Taking ABILIFY may make you sleepy or dizzy, cause a decrease in your blood pressure when changing position, or slow your thinking and motor skills which may lead to falls that can cause fractures or other injuries.</li> 2045 <li><strong>Low white blood cell count</strong></li> 2046 <li><strong>Seizures (convulsions)</strong></li> 2047 <li><strong>Problems with control of your body temperature especially when you exercise a lot or are in an area that is very hot. It is important for you to drink water to avoid dehydration.</strong> Avoid getting over-heated or dehydrated. Do not over-exercise. In hot weather, stay inside in a cool place if possible. Stay out of the sun. Do not wear too much or heavy clothing. Drink plenty of water.</li> 2048 <li><strong>Difficulty swallowing that can cause food or liquid to get into your lungs.</strong></li> 2049 </ul> 2050 2051 <p class="text-high">Do not drive, operate heavy machinery, or do other dangerous activities until you know how ABILIFY affects you. ABILIFY may make you drowsy.</p> 2052 <p class="text-high"><strong>Before taking ABILIFY, tell your healthcare provider about all your medical conditions, including if you have or had:</strong></p> 2053 2054 <ul class="medical-conditions"> 2055 <li> 2056 <p>diabetes or high blood sugar in you or your family; your healthcare provider should check your blood sugar before you start ABILIFY and also during therapy.</p> 2057 </li> 2058 <li> 2059 <p>seizures (convulsions).</p> 2060 </li> 2061 <li> 2062 <p>low or high blood pressure.</p> 2063 </li> 2064 <li> 2065 <p>heart problems or stroke.</p> 2066 </li> 2067 <li> 2068 <p>pregnancy or plans to become pregnant. It is not known if ABILIFY will harm your unborn baby. If you become pregnant while taking ABILIFY, talk to your healthcare provider about registering with the National Pregnancy Registry for Atypical Antipsychotics. You can register by calling <a tabindex="-1" href="tel:18669612388">1-866-961-2388</a> or go to <a class="link" href="http://womensmentalhealth.org/clinical-and-research-programs/pregnancyregistry/" target="_blank">http://womensmentalhealth.org/clinical-and-research-programs/pregnancyregistry/</a></p> 2069 </li> 2070 <li> 2071 <p>breast-feeding or plans to breast-feed. ABILIFY can pass into your breast milk and may harm your baby. Talk to your healthcare provider about the best way to feed your baby if you receive ABILIFY.</p> 2072 </li> 2073 <li> 2074 <p>low white blood cell count.</p> 2075 </li> 2076 </ul> 2077 2078 <p><strong>Tell your healthcare provider about all the medicines that you take,</strong> including prescription and over-the-counter medicines, vitamins, and herbal supplements.</p> 2079 2080 <p>ABILIFY and other medicines may affect each other causing possible serious side effects. ABILIFY may affect the way other medicines work, and other medicines may affect how ABILIFY works. Do not start or stop any medicines while taking ABILIFY without talking to your healthcare provider first.</p> 2081 2082 <p><strong>The most common side effects of ABILIFY in adults include:</strong> nausea, vomiting, constipation, headache, blurred vision, upper respiratory illness, dizziness, anxiety, insomnia, restlessness, and inner sense of restlessness or need to move (akathisia).</p> 2083 2084 <p><strong>The most common side effects of ABILIFY in children include:</strong> feeling sleepy, headache, vomiting, fatigue, increased or decreased appetite, increased saliva or drooling, insomnia, nausea, stuffy nose, weight gain, uncontrolled movement such as restlessness or tremor, and muscle stiffness.</p> 2085 2086 <p>It is important to contact your healthcare provider if you experience prolonged, abnormal muscle spasms or contractions, which may be signs of a condition called dystonia.</p> 2087 2088 <p>These are not all the possible side effects of ABILIFY.</p> 2089 2090 <p>Call your doctor for medical advice about side effects.</p> 2091 2092 <p><strong>If you have any questions about your health or medicines, talk to your healthcare provider.</strong></p> 2093 2094 <p>You are encouraged to report side effects of ABILIFY. Please contact Otsuka America Pharmaceutical, Inc. at <a tabindex="-1" href="tel:1-800-438-9927">1-800-438-9927</a> or FDA at <a tabindex="-1" href="tel:1-800-FDA-1088">1-800-FDA-1088</a> or <a class="link" href="https://www.fda.gov/medwatch" target="_blank">www.fda.gov/medwatch</a>.</p> 2095 </div> 2096 2097 <div class="isi-content-section"> 2098 <p class="isi-content-section-title">INDICATIONS:</p> 2099 <p>ABILIFY is indicated for:</p> 2100 2101 <ul> 2102 <li>Treatment of Schizophrenia in adults and in adolescents 13 to 17 years of age</li> 2103 <li>Treatment of manic or mixed episodes associated with Bipolar I Disorder in adults and in pediatric patients 10 to 17 years of age</li> 2104 <li>Use as an add-on treatment to an antidepressant for adults with Major Depressive Disorder who have had an inadequate response to antidepressant therapy</li> 2105 <li>Treatment of irritability associated with Autistic Disorder in pediatric patients 6 to 17 years of age</li> 2106 <li>Treatment of Tourette's Disorder in pediatric patients 6 to 18 years of age</li> 2107 </ul> 2108 2109 <p>Special Considerations for Pediatric Uses:</p> 2110 2111 <ul class="mt-2"> 2112 <li>Discuss the risks and benefits of treatment with your child's healthcare provider. Treatment should be started only after a thorough diagnostic evaluation and as part of a total treatment program</li> 2113 </ul> 2114 2115 <p>Please see <a class="link external-link-popup-disabled" href="https://www.otsuka-u
2115s.com/media/static/Abilify-PI.pdf" target="_blank">FULL PRESCRIBING INFORMATION</a>, including <strong>BOXED WARNING</strong>, and <a class="link external-link-popup-disabled" href="https://www.otsuka-us.com/media/static/Abilify-MedGuide.pdf" target="_blank">MEDICATION GUIDE</a>.</p> 2116 </div> 2117 </div> 2118 </div> 2119 </div> 2120 </div> 2121 </div> 2122 </div> 2123 </div> 2124 </div> 2125 </div> 2126 2127</section> 2128 2129 2130 2131 2132 2133 2134 2135 2136<div class="asimtufii-sound-block asimtufii-sound-block--sound d-none block-content-asimtufii-sound block-content-paragraphs" id="block-asimtufiisound" > 2137 <div class="audio"> 2138 2139 2140<audio controls="1" id="asimtufii-sound" tabindex="-1"> 2141 <source src="/sites/g/files/qhldwo13476/files/2024-01/AAA_clean_01.mp3" type="audio/mpeg"> 2142 Your browser does not support the audio tag. 2143</audio> 2144 </div> 2145 </div> 2146 2147 2148 2149 2150 </main> 2151 </div> 2152 2153 2154 2155<footer class="footer"> 2156 <div class="container-xl"> 2157 <div class="row"> 2158 2159 <div class="region_logo col-60 col-lg-25 d-flex justify-content-center justify-content-lg-start"> 2160 2161 2162 2163 2164 2165 2166 2167 2168<div class="branding branding--footer block-content-footer-branding block-content-paragraphs" id="block-footerbranding" > 2169 2170 2171 2172 2173<a 2174 class="link link--otsuka" 2175 target="_blank" 2176 data-analytics-name="Otsuka logo" 2177 aria-label=" 2178 2179 2180 2181 (opens in a new window)" 2182 href="https://www.otsuka-us.com/who-we-are" 2183> 2184 2185 2186 2187<img 2188 class="logo__image" 2189 src="/sites/g/files/qhldwo13476/files/2025-08/otsuka_logos.png" 2190 alt="Otsuka Logo" 2191 /> 2192 2193 </a> 2194 2195 2196 2197<a 2198 class="link link--lundbeck" 2199 target="_blank" 2200 data-analytics-name="Lundbeck logo" 2201 aria-label=" 2202 2203 2204 2205 (opens in a new window)" 2206 href="https://www.lundbeck.com/global" 2207> 2208 2209 2210 2211<img 2212 class="logo__image" 2213 src="/sites/g/files/qhldwo13476/files/2025-08/lundbeck_logos.png" 2214 alt="Lundbeck Logo" 2215 /> 2216 2217 </a> 2218 </div> 2219 2220 2221 2222 2223 2224 </div> 2225 2226 <div class="region_menu col-60 col-lg-35 text-center text-lg-start d-flex justify-content-center justify-content-lg-end"> 2227 2228 2229 2230 2231 2232<div id="block-block-otsuka-ds3-abilifyasimhcc-footer" id="block-otsuka-ds3-abilifyasimhcc-footer" class="system"> 2233 2234 2235 <nav role="navigation" aria-label="Footer Menu"> 2236 2237 2238 2239 2240 2241 2242 2243 2244<ul class="column-menu column-menu--footer navbar-nav list-unstyled"> 2245 2246 2247 2248 2249<li class="column-menu__item nav-item" > 2250 2251 2252 2253 2254 2255 2256 <a href="https://otsuka-us.com/media/static/Abilify-Asimtufii-PI.pdf" target="_blank" class="footer-pi link-pi external-link-popup-disabled column-menu-link nav-link" data-item-title="ABILIFY ASIMTUFII " aria-label="ABILIFY ASIMTUFII (opens in a new window)"> <span>ABILIFY ASIMTUFII </span> 2257 </a> 2258 </li> 2259 2260 2261 2262<li class="column-menu__item nav-item" > 2263 2264 2265 2266 2267 2268 2269 <a href="https://www.otsuka-us.com/media/static/Abilify-M-PI.pdf" target="_blank" class="link-pi external-link-popup-disabled column-menu-link nav-link" data-item-title="ABILIFY MAINTENA" aria-label="ABILIFY MAINTENA (opens in a new window)"> <span>ABILIFY MAINTENA</span> 2270 </a> 2271 </li> 2272 2273 2274 2275<li class="column-menu__item nav-item" > 2276 2277 2278 2279 2280 2281 2282 <a href="https://www.otsuka-us.com/media/static/Abilify-PI.pdf" target="_blank" class="external-link-popup-disabled column-menu-link nav-link" data-item-title="ABILIFY" aria-label="ABILIFY (opens in a new window)"> <span>ABILIFY</span> 2283 </a> 2284 </li> 2285 2286 2287 2288<li class="column-menu__item nav-item" > 2289 2290 2291 2292 2293 2294 2295 <a href="https://otsuka-us.com/media/static/Abilify-Asimtufii-MedGuide.pdf" target="_blank" class="footer-mg link-mg external-link-popup-disabled column-menu-link nav-link" data-item-title="ABILIFY ASIMTUFII" aria-label="ABILIFY ASIMTUFII (opens in a new window)">
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2479 <span class="text">Cancel</span> 2480 </button> 2481 </div> 2482 2483 2484 2485<button 2486 class="link__cta-none btn button btn-primary btn-ok" 2487 role="button" 2488 data-bs-dismiss="modal" 2489 id="externalLinkPopupModalContinueButton" 2490 data-test="modal-accept" 2491 > 2492 <span class="text">OK</span> 2493 </button> 2494 </div> 2495 </div> 2496 </div> 2497 </div> 2498 </div> 2499 2500 2501 2502 2503 2504 2505 2506 2507 2508 2509 2510 2511 <section aria-labelledby="drawer-title" role="complementary" id="drawer-isi" 2512 class="isi-tray jsIsiContainer isi-drawer-collapsed hide-tray not-displayed" 2513 data-analytics-group="ISI" data-test='isi-drawer'> 2514 2515 <!--<div id="isi-drawer-wrapper" class="isi-drawer-collapsed">--> 2516 2517 <div class="isi-header"> 2518 <div class="isi-header-wrap"> 2519 <div id="drawer-title" class="drawer-title"> <div class="general">IMPORTANT SAFETY INFORMATION and INDICATIONS</div><div class="saving-card-asim">INDICATIONS and IMPORTANT SAFETY INFORMATION for ABILIFY ASIMTUFII<sup class="rball">®</sup> (aripiprazole)</div><div class="saving-card-abim">INDICATIONS and IMPORTANT SAFETY INFORMATION for ABILIFY MAINTENA<sup class="rball">®</sup> (aripiprazole)</div> 2520 </div> 2521 <button title="ISI Minimize" 2522 class="isi-btn jsIsiMinimize" 2523 data-oapigtmcategory="Button Clicks" data-oapigtmaction="ISI" 2524 data-oapigtmlabel="" tabindex="-1" 2525 data-analytics-name="Collapse/Expand ISI"> 2526 <span 2527 class="jsSwapText jsSwapTextExpand"></span> 2528 <span 2529 class="jsSwapText jsSwapTextCollapse hide"></span> 2530 <span class="isi-btn-icon"></span></button> 2531 </div> 2532 </div> 2533 2534 <div class="isi isi-block isi-drawer-content isi-content-wrap"> 2535 <div class="jcf-scrollable jcf-container mCustomScrollbar"> 2536 <div class="tabs tabs--general" data-test="tabs"> 2537 <div class="container-lg"> 2538 <div class="row"> 2539 <div class="col-60 col-tabs d-block"> 2540 <ul class="nav nav nav-tabs" id="ISITrayTabsDesktop" role="tablist" data-test="tabs-titles"> 2541 <li class="nav__item nav-item"> 2542 <button class="nav__btn nav__btn--active btn-none btn-md nav-link active" id="ISITrayTabsDesktop_0-tab" data-bs-toggle="tab" data-bs-target="#ISITrayTabsDesktop_0" type="button" role="tab" aria-controls="ISITrayTabsDesktop_0" aria-selected="false" data-test="tabs-item"> 2543 ABILIFY ASIMTUFII<sup class="rball">®</sup> (aripiprazole) and ABILIFY MAINTENA<sup class="rball">®</sup> (aripiprazole) 2544 </button> 2545 </li> 2546 <li class="nav__item nav-item"> 2547 <button class="nav__btn btn-none btn-md nav-link" id="ISITrayTabsDesktop_1-tab" data-bs-toggle="tab" data-bs-target="#ISITrayTabsDesktop_1" type="button" role="tab" aria-controls="ISITrayTabsDesktop_1" aria-selected="false" data-test="tabs-item"> 2548 ABILIFY<sup class="rball">®</sup> (aripiprazole) 2549 </button> 2550 </li> 2551 </ul> 2552 <div class="tab-content" id="ISITrayTabsDesktop_Content"> 2553 <div class="tab-pane fade show active" data-test="tabs-content" id="ISITrayTabsDesktop_0" role="tabpanel" aria-labelledby="ISITrayTabsDesktop_0"> 2554 <div class="tab-pane__text"> 2555 <div class="isi-content-section"> 2556 <p class="isi-content-section-title d-block">IMPORTANT SAFETY INFORMATION:</p> 2557 2558 <p class="text-close"><strong>Increased risk of death in elderly people with dementia-related psychosis. </strong><strong>ABILIFY ASIMTUFII</strong><strong> and </strong><strong>ABILIFY MAINTENA</strong><strong> increase the risk of death in elderly people who have lost touch with reality (psychosis) due to confusion and memory loss (dementia). </strong><strong>ABILIFY ASIMTUFII</strong><strong> and </strong><strong>ABILIFY MAINTENA</strong><strong> are not for the treatment of people with dementia-related psychosis.</strong></p> 2559 2560 <p class="text-close"><strong>Do not receive ABILIFY ASIMTUFII or ABILIFY MAINTENA if you </strong>are allergic to aripiprazole or any of the ingredients in ABILIFY ASIMTUFII or ABILIFY MAINTENA.</p> 2561 2562 <p><strong>ABILIFY ASIMTUFII or ABILIFY MAINTENA may cause serious side effects, including:</strong></p> 2563 2564 <ul> 2565 <li><strong>Increased risk of stroke</strong> and ministroke has been reported in clinical studies with oral aripiprazole of elderly people with dementia-related psychosis and can lead to death.</li> 2566 <li><strong>Neuroleptic malignant syndrome (NMS), a serious condition that can lead to death.</strong> Call your healthcare provider or go to the nearest emergency room right away if you have some or all of the following signs and symptoms of NMS: high fever, confusion, changes in pulse, heart rate, and blood pressure, stiff muscles, and increased sweating.</li> 2567 <li><strong>Uncontrolled body movements (tardive dyskinesia).</strong> ABILIFY ASIMTUFII and ABILIFY MAINTENA may cause movements that you cannot control in your face, tongue, or other body parts. Tardive dyskinesia may not go away, even if you stop receiving ABILIFY ASIMTUFII or ABILIFY MAINTENA. Tardive dyskinesia may also start after you stop receiving ABILIFY ASIMTUFII or ABILIFY MAINTENA.</li> 2568 <li><strong>Problems with your metabolism such as:</strong> 2569 <ul> 2570 <li> 2571 <p><strong>High blood sugar (hyperglycemia) and diabetes:</strong> Increases in blood sugar can happen in some people who are treated with ABILIFY ASIMTUFII or ABILIFY MAINTENA. Extremely high blood sugar can lead to coma or death. If you have diabetes or risk factors for diabetes such as being overweight or a family history of diabetes, your healthcare provider should check your blood sugar before you start treatment with ABILIFY ASIMTUFII or ABILIFY MAINTENA, and during treatment.</p> 2572 </li> 2573 </ul> 2574 2575 <p class="left-indent"><strong>Call your healthcare provider if you have any of these symptoms of high blood sugar during treatment with ABILIFY ASIMTUFII or ABILIFY MAINTENA:</strong></p> 2576 </li> 2577 </ul> 2578 2579 <ul class="left-indent"> 2580 <li> 2581 <p>feel very thirsty</p> 2582 </li> 2583 <li> 2584 <p>need to urinate more than usual</p> 2585 </li> 2586 <li> 2587 <p>feel very hungry</p> 2588 </li> 2589 <li> 2590 <p>feel weak or tired</p> 2591 </li> 2592 <li> 2593 <p>feel sick to your stomach</p> 2594 </li> 2595 <li> 2596 <p>feel confused, or your breath smells fruity</p> 2597 </li> 2598 </ul> 2599 2600 <ul class="arrow-indent"> 2601 <li><strong>Increased fat levels (cholesterol and triglycerides) in your blood.</strong></li> 2602 <li><strong>Weight gain.</strong> You and your healthcare provider should check your weight regularly during treatment.</li> 2603 </ul> 2604 2605 <ul class="symptoms-extended"> 2606 <li><strong>Unusual and uncontrollable (compulsive) urges.</strong> Some people receiving ABILIFY ASIMTUFII or ABILIFY MAINTENA have had unusual strong urges to gamble and gambling that cannot be controlled (compulsive gambling). Other
2606compulsive urges include sexual urges, shopping, and eating or binge eating. If you or your family members notice that you are having unusual urges or behaviors, talk to your healthcare provider.</li> 2607 <li><strong>Decreased blood pressure (orthostatic hypotension).</strong> You may feel lightheaded or faint when you rise too quickly from a sitting or lying position.</li> 2608 <li><strong>Falls.</strong> ABILIFY ASIMTUFII and ABILIFY MAINTENA may make you sleepy or dizzy, may cause a decrease in your blood pressure when changing position (orthostatic hypotension), and can slow your thinking and motor skills, which may lead to falls that can cause fractures or other injuries.</li> 2609 <li><strong>Low white blood cell count.</strong> Your healthcare provider may do blood tests during the first few months of treatment.</li> 2610 <li><strong>Seizures (convulsions)</strong></li> 2611 <li><strong>Sleepiness, drowsiness, feeling tired, difficulty thinking and doing normal activities. Do not</strong> drive a car, operate machinery, or do other dangerous activities until you know how ABILIFY ASIMTUFII or ABILIFY MAINTENA affects you. ABILIFY ASIMTUFII or ABILIFY MAINTENA may make you feel drowsy and affect your judgement, thinking, or motor skills.</li> 2612 <li><strong>Problems controlling your body temperature so that you feel too warm. Do not</strong> become too hot or dehydrated during treatment with ABILIFY ASIMTUFII or ABILIFY MAINTENA. <strong>Do not</strong> exercise too much. In hot weather, stay inside in a cool place if possible. Stay out of the sun. <strong>Do not</strong> wear too much clothing or heavy clothing. Drink plenty of water.</li> 2613 <li><strong>Difficulty swallowing</strong> that can cause food or liquid to get into your lungs.</li> 2614 </ul> 2615 2616 <p class="text-high"><strong>Do not</strong> drink alcohol during treatment with ABILIFY ASIMTUFII or ABILIFY MAINTENA.</p> 2617 2618 <p class="text-high"><strong>Before receiving ABILIFY ASIMTUFII or ABILIFY MAINTENA, tell your healthcare provider about all your medical conditions, including if you:</strong></p> 2619 2620 <ul class="medical-conditions"> 2621 <li> 2622 <p>have never taken aripiprazole before</p> 2623 </li> 2624 <li> 2625 <p>have or had diabetes or high blood sugar or a family history of diabetes or high blood sugar</p> 2626 </li> 2627 <li> 2628 <p>have or had high levels of total cholesterol, LDL cholesterol, or triglycerides, or low levels of HDL cholesterol</p> 2629 </li> 2630 <li> 2631 <p>have or had low or high blood pressure</p> 2632 </li> 2633 <li> 2634 <p>have or had heart problems or a stroke</p> 2635 </li> 2636 <li> 2637 <p>have or had a low white blood cell count</p> 2638 </li> 2639 <li> 2640 <p>have or had seizures (convulsions)</p> 2641 </li> 2642 <li> 2643 <p>have problems that may affect you receiving an injection in your buttocks (ABILIFY ASIMTUFII and ABILIFY MAINTENA) or arm (ABILIFY MAINTENA)</p> 2644 </li> 2645 <li> 2646 <p>are pregnant or plan to become pregnant. ABILIFY ASIMTUFII or ABILIFY MAINTENA may harm your unborn baby. If you become pregnant during treatment with ABILIFY ASIMTUFII or ABILIFY MAINTENA, talk to your healthcare provider about the risk to your unborn baby and about registering with the National Pregnancy Registry for Atypical Antipsychotics. You can register by calling <a tabindex="-1" href="tel:18669612388">1-866-961-2388</a> or visit <a class="link" href="http://womensmentalhealth.org/clinical-and-research-programs/pregnancyregistry/" target="_blank">http://womensmentalhealth.org/clinical-and-research-programs/pregnancyregistry/</a></p> 2647 </li> 2648 <li> 2649 <p>are breastfeeding or plan to breastfeed. ABILIFY ASIMTUFII or ABILIFY MAINTENA can pass into your milk and may harm your baby. Talk to your healthcare provider about the best way to feed your baby if you receive ABILIFY ASIMTUFII or ABILIFY MAINTENA.</p> 2650 </li> 2651 </ul> 2652 2653 <p><strong>Tell your healthcare provider about all the medicines you take,</strong> including prescription medicines and over-the-counter medicines, vitamins, and herbal supplements.</p> 2654 2655 <p>ABILIFY ASIMTUFII or ABILIFY MAINTENA and other medicines may affect each other, causing possible serious side effects. Do not start or stop any medicines during treatment with ABILIFY ASIMTUFII or ABILIFY MAINTENA without talking to your healthcare provider first.</p> 2656 2657 <p><strong>The most common side effects of ABILIFY ASIMTUFII or ABILIFY MAINTENA include:</strong> weight gain, restlessness or feeling like you need to move (akathisia), injection site pain, or sleepiness (sedation).</p> 2658 2659 <p>It is important to contact your healthcare provider if you experience prolonged, abnormal muscle spasms or contractions, which may be signs of a condition called dystonia.</p> 2660 2661 <p>These are not all the possible side effects of ABILIFY ASIMTUFII or ABILIFY MAINTENA.</p> 2662 2663 <p><strong>If you have any questions about your health or medicines, talk to your healthcare provider.</strong></p> 2664 2665 <p>You are encouraged to report side effects of ABILIFY ASIMTUFII and ABILIFY MAINTENA. Please contact Otsuka America Pharmaceutical, Inc. at <a tabindex="-1" href="tel:1-800-438-9927">1-800-438-9927</a> or FDA at <a tabindex="-1" href="tel:1-800-FDA-1088">1-800-FDA-1088</a> (<a class="link" href="https://www.fda.gov/medwatch" target="_blank">www.fda.gov/medwatch</a>).</p> 2666 </div> 2667 2668 <div class="isi-content-section"> 2669 <p class="isi-content-section-title">INDICATIONS:</p> 2670 <p>ABILIFY ASIMTUFII is a prescription medicine given by injection by a healthcare professional:</p> 2671 2672 <ul class="no-left-ident"> 2673 <li>for the treatment of schizophrenia in adults</li> 2674 <li>alone as maintenance treatment of bipolar I disorder in adults</li> 2675 </ul> 2676 2677 <p>ABILIFY MAINTENA is a prescription medicine given by injection by a healthcare professional:</p> 2678 2679 <ul class="mt-2"> 2680 <li>for the treatment of schizophrenia in adults</li> 2681 <li>alone as maintenance treatment of bipolar I disorder in adults</li> 2682 </ul> 2683 2684 <p>It is not known if ABILIFY ASIMTUFII or ABILIFY MAINTENA is safe and effective in children under 18 years of age.</p> 2685 <p>Please see FULL PRESCRIBING INFORMATION, including <strong>BOXED WARNING</strong>, for <a class="link external-link-popup-disabled" href="https://www.otsuka-u
2685s.com/media/static/Abilify-Asimtufii-PI.pdf" target="_blank">ABILIFY ASIMTUFII</a> and <a class="link external-link-popup-disabled" href="https://www.otsuka-us.com/media/static/Abilify-M-PI.pdf" target="_blank">ABILIFY MAINTENA</a>, and MEDICATION GUIDE for <a class="link external-link-popup-disabled" href="https://www.otsuka-us.com/media/static/Abilify-Asimtufii-MedGuide.pdf" target="_blank">ABILIFY ASIMTUFII</a> and <a class="link external-link-popup-disabled" href="https://www.otsuka-us.com/media/static/Abilify-M-Medguide.pdf" target="_blank">ABILIFY MAINTENA</a>.</p> 2686 </div> 2687 </div> 2688 </div> 2689 <div class="tab-pane fade " data-test="tabs-content" id="ISITrayTabsDesktop_1" role="tabpanel" aria-labelledby="ISITrayTabsDesktop_1"> 2690 <div class="tab-pane__text"> 2691 <div class="isi-content-section"> 2692 <p class="isi-content-section-title d-block">IMPORTANT SAFETY INFORMATION:</p> 2693 2694 <p class="text-close"><strong>Elderly people with psychosis related to dementia treated with antipsychotic medicines including ABILIFY, are at an increased risk of death compared to placebo. ABILIFY is not approved for the treatment of people with dementia-related psychosis.</strong></p> 2695 2696 <p class="text-close"><strong>Antidepressant medicines may increase suicidal thoughts or behaviors in some children, teenagers, and young adults, especially within the first few months of treatment or when the dose is changed.</strong></p> 2697<p class="text-close"><strong>Depression and other serious mental illnesses are themselves associated with an increase in the risk of suicide. Patients on antidepressants and their families or caregivers should watch for new or worsening depression symptoms, unusual changes in behavior, or thoughts of suicide. Such symptoms should be reported to the patient's healthcare provider right away, especially if they are severe or occur suddenly. ABILIFY is not approved for use in pediatric patients with depression.</strong></p> 2698 2699 <p class="text-close"><strong>Do not take ABILIFY if you </strong>are allergic to aripiprazole or any of the ingredients in ABILIFY. Allergic reactions have ranged from rash, hives, and itching to anaphylaxis, which may include difficulty breathing, tightness in the chest, and swelling of the mouth, face, lips, or tongue.</p> 2700 2701 <p><strong>ABILIFY may cause serious side effects, including:</strong></p> 2702 2703 <ul> 2704 <li><strong>Stroke in elderly people (cerebrovascular problems) that can lead to death</strong></li> 2705 <li><strong>Neuroleptic malignant syndrome (NMS).</strong> Tell your healthcare provider right away if you have some or all of the following symptoms: high fever, stiff muscles, confusion, sweating, changes in pulse, heart rate, and blood pressure. These may be symptoms of a rare and serious condition that can lead to death. Call your healthcare provider right away if you have any of these symptoms.</li> 2706 <li><strong>Uncontrolled body movements (tardive dyskinesia).</strong> ABILIFY may cause movements that you cannot control in your face, tongue, or other body parts. Tardive dyskinesia may not go away, even if you stop receiving ABILIFY. Tardive dyskinesia may also start after you stop receiving ABILIFY.</li> 2707 <li><strong>Problems with your metabolism such as:</strong> 2708 <ul> 2709 <li> 2710 <p><strong>High blood sugar (hyperglycemia) and diabetes.</strong> Increases in blood sugar can happen in some people who take ABILIFY. Extremely high blood sugar can lead to coma or death. If you have diabetes or risk factors for diabetes (such as being overweight or a family history of diabetes), your healthcare provider should check your blood sugar before you start ABILIFY and during your treatment.</p> 2711 </li> 2712 </ul> 2713 2714 <p class="left-indent"><strong>Call your healthcare provider if you have any of these symptoms of high blood sugar while receiving ABILIFY:</strong></p> 2715 </li> 2716 </ul> 2717 2718 <ul class="left-indent"> 2719 <li> 2720 <p>feel very thirsty</p> 2721 </li> 2722 <li> 2723 <p>need to urinate more than usual</p> 2724 </li> 2725 <li> 2726 <p>feel very hungry</p> 2727 </li> 2728 <li> 2729 <p>feel weak or tired</p> 2730 </li> 2731 <li> 2732 <p>feel sick to your stomach</p> 2733 </li> 2734 <li> 2735 <p>feel confused, or your breath smells fruity</p> 2736 </li> 2737 </ul> 2738 2739 <ul class="arrow-indent"> 2740 <li><strong>Increased fat levels (cholesterol and triglycerides) in your blood.</strong></li> 2741 <li><strong>Weight gain.</strong> You and your healthcare provider should check your weight regularly.</li> 2742 </ul> 2743 2744 <ul class="symptoms-extended"> 2745 <li><strong>Unusual urges.</strong> Some people taking ABILIFY have had unusual urges, such as gambling, binge eating or eating that you cannot control (compulsive), compulsive shopping and sexual urges. If you or your family members notice that you are having unusual urges or behaviors, talk to your healthcare provider.</li> 2746 <li><strong>Orthostatic hypotension (decreased blood pressure).</strong> Lightheadedness or fainting may happen when rising too quickly from a sitting or lying position.</li> 2747 <li><strong>Falls.</strong>
2747 Taking ABILIFY may make you sleepy or dizzy, cause a decrease in your blood pressure when changing position, or slow your thinking and motor skills which may lead to falls that can cause fractures or other injuries.</li> 2748 <li><strong>Low white blood cell count</strong></li> 2749 <li><strong>Seizures (convulsions)</strong></li> 2750 <li><strong>Problems with control of your body temperature especially when you exercise a lot or are in an area that is very hot. It is important for you to drink water to avoid dehydration.</strong> Avoid getting over-heated or dehydrated. Do not over-exercise. In hot weather, stay inside in a cool place if possible. Stay out of the sun. Do not wear too much or heavy clothing. Drink plenty of water.</li> 2751 <li><strong>Difficulty swallowing that can cause food or liquid to get into your lungs.</strong></li> 2752 </ul> 2753 2754 <p class="text-high">Do not drive, operate heavy machinery, or do other dangerous activities until you know how ABILIFY affects you. ABILIFY may make you drowsy.</p> 2755 <p class="text-high"><strong>Before taking ABILIFY, tell your healthcare provider about all your medical conditions, including if you have or had:</strong></p> 2756 2757 <ul class="medical-conditions"> 2758 <li> 2759 <p>diabetes or high blood sugar in you or your family; your healthcare provider should check your blood sugar before you start ABILIFY and also during therapy.</p> 2760 </li> 2761 <li> 2762 <p>seizures (convulsions).</p> 2763 </li> 2764 <li> 2765 <p>low or high blood pressure.</p> 2766 </li> 2767 <li> 2768 <p>heart problems or stroke.</p> 2769 </li> 2770 <li> 2771 <p>pregnancy or plans to become pregnant. It is not known if ABILIFY will harm your unborn baby. If you become pregnant while taking ABILIFY, talk to your healthcare provider about registering with the National Pregnancy Registry for Atypical Antipsychotics. You can register by calling <a tabindex="-1" href="tel:18669612388">1-866-961-2388</a> or go to <a class="link" href="http://womensmentalhealth.org/clinical-and-research-programs/pregnancyregistry/" target="_blank">http://womensmentalhealth.org/clinical-and-research-programs/pregnancyregistry/</a></p> 2772 </li> 2773 <li> 2774 <p>breast-feeding or plans to breast-feed. ABILIFY can pass into your breast milk and may harm your baby. Talk to your healthcare provider about the best way to feed your baby if you receive ABILIFY.</p> 2775 </li> 2776 <li> 2777 <p>low white blood cell count.</p> 2778 </li> 2779 </ul> 2780 2781 <p><strong>Tell your healthcare provider about all the medicines that you take,</strong> including prescription and over-the-counter medicines, vitamins, and herbal supplements.</p> 2782 2783 <p>ABILIFY and other medicines may affect each other causing possible serious side effects. ABILIFY may affect the way other medicines work, and other medicines may affect how ABILIFY works. Do not start or stop any medicines while taking ABILIFY without talking to your healthcare provider first.</p> 2784 2785 <p><strong>The most common side effects of ABILIFY in adults include:</strong> nausea, vomiting, constipation, headache, blurred vision, upper respiratory illness, dizziness, anxiety, insomnia, restlessness, and inner sense of restlessness or need to move (akathisia).</p> 2786 2787 <p><strong>The most common side effects of ABILIFY in children include:</strong> feeling sleepy, headache, vomiting, fatigue, increased or decreased appetite, increased saliva or drooling, insomnia, nausea, stuffy nose, weight gain, uncontrolled movement such as restlessness or tremor, and muscle stiffness.</p> 2788 2789 <p>It is important to contact your healthcare provider if you experience prolonged, abnormal muscle spasms or contractions, which may be signs of a condition called dystonia.</p> 2790 2791 <p>These are not all the possible side effects of ABILIFY.</p> 2792 2793 <p>Call your doctor for medical advice about side effects.</p> 2794 2795 <p><strong>If you have any questions about your health or medicines, talk to your healthcare provider.</strong></p> 2796 2797 <p>You are encouraged to report side effects of ABILIFY. Please contact Otsuka America Pharmaceutical, Inc. at <a tabindex="-1" href="tel:1-800-438-9927">1-800-438-9927</a> or FDA at <a tabindex="-1" href="tel:1-800-FDA-1088">1-800-FDA-1088</a> or <a class="link" href="https://www.fda.gov/medwatch" target="_blank">www.fda.gov/medwatch</a>.</p> 2798 </div> 2799 2800 <div class="isi-content-section"> 2801 <p class="isi-content-section-title">INDICATIONS:</p> 2802 <p>ABILIFY is indicated for:</p> 2803 2804 <ul> 2805 <li>Treatment of Schizophrenia in adults and in adolescents 13 to 17 years of age</li> 2806 <li>Treatment of manic or mixed episodes associated with Bipolar I Disorder in adults and in pediatric patients 10 to 17 years of age</li> 2807 <li>Use as an add-on treatment to an antidepressant for adults with Major Depressive Disorder who have had an inadequate response to antidepressant therapy</li> 2808 <li>Treatment of irritability associated with Autistic Disorder in pediatric patients 6 to 17 years of age</li> 2809 <li>Treatment of Tourette's Disorder in pediatric patients 6 to 18 years of age</li> 2810 </ul> 2811 2812 <p>Special Considerations for Pediatric Uses:</p> 2813 2814 <ul class="mt-2"> 2815 <li>Discuss the risks and benefits of treatment with your child's healthcare provider. Treatment should be started only after a thorough diagnostic evaluation and as part of a total treatment program</li> 2816 </ul> 2817 2818 <p>Please see <a class="link external-link-popup-disabled" href="https://www.otsuka-u
2818s.com/media/static/Abilify-PI.pdf" target="_blank">FULL PRESCRIBING INFORMATION</a>, including <strong>BOXED WARNING</strong>, and <a class="link external-link-popup-disabled" href="https://www.otsuka-us.com/media/static/Abilify-MedGuide.pdf" target="_blank">MEDICATION GUIDE</a>.</p> 2819 </div> 2820 </div> 2821 </div> 2822 </div> 2823 </div> 2824 </div> 2825 </div> 2826 </div> 2827<div class="saving-card-asim"> 2828 <div class="isi-content-section"> 2829 <p class="isi-content-section-title">INDICATIONS:</p> 2830 <p>ABILIFY ASIMTUFII is a prescription medicine given by injection by a healthcare professional:</p> 2831 2832 <ul class="no-left-ident"> 2833 <li>for the treatment of schizophrenia in adults</li> 2834 <li>alone as maintenance treatment of bipolar I disorder in adults</li> 2835 </ul> 2836 2837 <p>It is not known if ABILIFY ASIMTUFII is safe and effective in children under 18 years of age.</p> 2838 </div> 2839 <div class="isi-content-section"> 2840 <p class="isi-content-section-title d-block">IMPORTANT SAFETY INFORMATION:</p> 2841 2842 <p class="text-close"><strong>Increased risk of death in elderly people with dementia-related psychosis. ABILIFY ASIMTUFII increase the risk of death in elderly people who have lost touch with reality (psychosis) due to confusion and memory loss (dementia). ABILIFY ASIMTUFII are not for the treatment of people with dementia-related psychosis.</strong></p> 2843 2844 <p class="text-close"><strong>Do not receive ABILIFY ASIMTUFII if you </strong>are allergic to aripiprazole or any of the ingredients in ABILIFY ASIMTUFII.</p> 2845 2846 <p><strong>ABILIFY ASIMTUFII may cause serious side effects, including:</strong></p> 2847 2848 <ul> 2849 <li><strong>Increased risk of stroke</strong> and ministroke has been reported in clinical studies with oral aripiprazole of elderly people with dementia-related psychosis and can lead to death.</li> 2850 <li><strong>Neuroleptic malignant syndrome (NMS), a serious condition that can lead to death.</strong> Call your healthcare provider or go to the nearest emergency room right away if you have some or all of the following signs and symptoms of NMS: high fever, confusion, changes in pulse, heart rate, and blood pressure, stiff muscles, and increased sweating.</li> 2851 <li><strong>Uncontrolled body movements (tardive dyskinesia).</strong> ABILIFY ASIMTUFII may cause movements that you cannot control in your face, tongue, or other body parts. Tardive dyskinesia may not go away, even if you stop receiving ABILIFY ASIMTUFII. Tardive dyskinesia may also start after you stop receiving ABILIFY ASIMTUFII.</li> 2852 <li><strong>Problems with your metabolism such as:</strong> 2853 <ul> 2854 <li> 2855 <p><strong>High blood sugar (hyperglycemia) and diabetes:</strong> Increases in blood sugar can happen in some people who are treated with ABILIFY ASIMTUFII. Extremely high blood sugar can lead to coma or death. If you have diabetes or risk factors for diabetes such as being overweight or a family history of diabetes, your healthcare provider should check your blood sugar before you start treatment with ABILIFY ASIMTUFII, and during treatment.</p> 2856 </li> 2857 </ul> 2858 2859 <p class="left-indent"><strong>Call your healthcare provider if you have any of these symptoms of high blood sugar during treatment with ABILIFY ASIMTUFII:</strong></p> 2860 </li> 2861 </ul> 2862 2863 <ul class="left-indent"> 2864 <li> 2865 <p>feel very thirsty</p> 2866 </li> 2867 <li> 2868 <p>need to urinate more than usual</p> 2869 </li> 2870 <li> 2871 <p>feel very hungry</p> 2872 </li> 2873 <li> 2874 <p>feel weak or tired</p> 2875 </li> 2876 <li> 2877 <p>feel sick to your stomach</p> 2878 </li> 2879 <li> 2880 <p>feel confused, or your breath smells fruity</p> 2881 </li> 2882 </ul> 2883 2884 <ul class="arrow-indent"> 2885 <li><strong>Increased fat levels (cholesterol and triglycerides) in your blood.</strong></li> 2886 <li><strong>Weight gain.</strong> You and your healthcare provider should check your weight regularly during treatment.</li> 2887 </ul> 2888 2889 <ul class="symptoms-extended"> 2890 <li><strong>Unusual and uncontrollable (compulsive) urges.</strong> Some people receiving ABILIFY ASIMTUFII have had unusual strong urges to gamble and gambling that cannot be controlled (compulsive gambling). Other
2890compulsive urges include sexual urges, shopping, and eating or binge eating. If you or your family members notice that you are having unusual urges or behaviors, talk to your healthcare provider.</li> 2891 <li><strong>Decreased blood pressure (orthostatic hypotension).</strong> You may feel lightheaded or faint when you rise too quickly from a sitting or lying position.</li> 2892 <li><strong>Falls.</strong> ABILIFY ASIMTUFII may make you sleepy or dizzy, may cause a decrease in your blood pressure when changing position (orthostatic hypotension), and can slow your thinking and motor skills, which may lead to falls that can cause fractures or other injuries.</li> 2893 <li><strong>Low white blood cell count.</strong> Your healthcare provider may do blood tests during the first few months of treatment.</li> 2894 <li><strong>Seizures (convulsions)</strong></li> 2895 <li><strong>Sleepiness, drowsiness, feeling tired, difficulty thinking and doing normal activities. Do not</strong> drive a car, operate machinery, or do other dangerous activities until you know how ABILIFY ASIMTUFII affects you. ABILIFY ASIMTUFII may make you feel drowsy and affect your judgement, thinking, or motor skills.</li> 2896 <li><strong>Problems controlling your body temperature so that you feel too warm. Do not</strong> become too hot or dehydrated during treatment with ABILIFY ASIMTUFII. <strong>Do not</strong> exercise too much. In hot weather, stay inside in a cool place if possible. Stay out of the sun. <strong>Do not</strong> wear too much clothing or heavy clothing. Drink plenty of water.</li> 2897 <li><strong>Difficulty swallowing</strong> that can cause food or liquid to get into your lungs.</li> 2898 </ul> 2899 2900 <p class="text-high"><strong>Do not</strong> drink alcohol during treatment with ABILIFY ASIMTUFII.</p> 2901 2902 <p class="text-high"><strong>Before receiving ABILIFY ASIMTUFII, tell your healthcare provider about all your medical conditions, including if you:</strong></p> 2903 2904 <ul class="medical-conditions"> 2905 <li> 2906 <p>have never taken aripiprazole before</p> 2907 </li> 2908 <li> 2909 <p>have or had diabetes or high blood sugar or a family history of diabetes or high blood sugar</p> 2910 </li> 2911 <li> 2912 <p>have or had high levels of total cholesterol, LDL cholesterol, or triglycerides, or low levels of HDL cholesterol</p> 2913 </li> 2914 <li> 2915 <p>have or had low or high blood pressure</p> 2916 </li> 2917 <li> 2918 <p>have or had heart problems or a stroke</p> 2919 </li> 2920 <li> 2921 <p>have or had a low white blood cell count</p> 2922 </li> 2923 <li> 2924 <p>have or had seizures (convulsions)</p> 2925 </li> 2926 <li> 2927 <p>have problems that may affect you receiving an injection in your buttocks</p> 2928 </li> 2929 <li> 2930 <p>are pregnant or plan to become pregnant. ABILIFY ASIMTUFII may harm your unborn baby. If you become pregnant during treatment with ABILIFY ASIMTUFII, talk to your healthcare provider about the risk to your unborn baby and about registering with the National Pregnancy Registry for Atypical Antipsychotics. You can register by calling <a tabindex="-1" href="tel:18669612388">1-866-961-2388</a> or visit <a class="link" href="http://womensmentalhealth.org/clinical-and-research-programs/pregnancyregistry/" target="_blank">http://womensmentalhealth.org/clinical-and-research-programs/pregnancyregistry/</a></p> 2931 </li> 2932 <li> 2933 <p>are breastfeeding or plan to breastfeed. ABILIFY ASIMTUFII can pass into your milk and may harm your baby. Talk to your healthcare provider about the best way to feed your baby if you receive ABILIFY ASIMTUFII.</p> 2934 </li> 2935 </ul> 2936 2937 <p><strong>Tell your healthcare provider about all the medicines you take,</strong> including prescription medicines and over-the-counter medicines, vitamins, and herbal supplements.</p> 2938 2939 <p>ABILIFY ASIMTUFII and other medicines may affect each other, causing possible serious side effects. Do not start or stop any medicines during treatment with ABILIFY ASIMTUFII without talking to your healthcare provider first.</p> 2940 2941 <p><strong>The most common side effects of ABILIFY ASIMTUFII include:</strong> weight gain, restlessness or feeling like you need to move (akathisia), injection site pain, or sleepiness (sedation).</p> 2942 2943 <p>It is important to contact your healthcare provider if you experience prolonged, abnormal muscle spasms or contractions, which may be signs of a condition called dystonia.</p> 2944 2945 <p>These are not all the possible side effects of ABILIFY ASIMTUFII.</p> 2946 2947 <p><strong>If you have any questions about your health or medicines, talk to your healthcare provider.</strong></p> 2948 2949 <p>You are encouraged to report side effects of ABILIFY ASIMTUFII. Please contact Otsuka America Pharmaceutical, Inc. at <a tabindex="-1" href="tel:1-800-438-9927">1-800-438-9927</a> or FDA at <a tabindex="-1" href="tel:1-800-FDA-1088">1-800-FDA-1088</a> (<a class="link" href="https://www.fda.gov/medwatch" target="_blank">www.fda.gov/medwatch</a>).</p> 2950 </div> 2951 2952 <div class="isi-content-section"> 2953 <p>Please see <a class="link external-link-popup-disabled" href="https://otsuka-us.com/media/static/Abilify-Asimtufii-PI.pdf" target="_blank">FULL PRESCRIBING INFORMATION</a>, including <strong>BOXED WARNING</strong>, and <a class="link external-link-popup-disabled" href="https://otsuka-us.com/media/static/Abilify-Asimtufii-MedGuide.pdf" target="_blank">MEDICATION GUIDE</a>.</p> 2954 </div> 2955</div> 2956<div class="saving-card-abim"> 2957 <div class="isi-content-section"> 2958 <p class="isi-content-section-title">INDICATIONS:</p> 2959 2960 <p>ABILIFY MAINTENA is a prescription medicine given by injection by a healthcare professional:</p> 2961 2962 <ul class="mt-2"> 2963 <li>for the treatment of schizophrenia in adults</li> 2964 <li>alone as maintenance treatment of bipolar I disorder in adults</li> 2965 </ul> 2966 2967 <p>It is not known if ABILIFY MAINTENA is safe and effective in children under 18 years of age.</p> 2968 </div> 2969 2970 <div class="isi-content-section"> 2971 <p class="isi-content-section-title d-block">IMPORTANT SAFETY INFORMATION:</p> 2972 2973 <p class="text-close"><strong>Increased risk of death in elderly people with dementia-related psychosis. ABILIFY MAINTENA increase the risk of death in elderly people who have lost touch with reality (psychosis) due to confusion and memory loss (dementia). ABILIFY MAINTENA are not for the treatment of people with dementia-related psychosis.</strong></p> 2974 2975 <p class="text-close"><strong>Do not receive ABILIFY MAINTENA if you </strong>are allergic to aripiprazole or any of the ingredients in ABILIFY MAINTENA.</p> 2976 2977 <p><strong>ABILIFY MAINTENA may cause serious side effects, including:</strong></p> 2978 2979 <ul> 2980 <li><strong>Increased risk of stroke</strong> and ministroke has been reported in clinical studies with oral aripiprazole of elderly people with dementia-related psychosis and can lead to death.</li> 2981 <li><strong>Neuroleptic malignant syndrome (NMS), a serious condition that can lead to death.</strong> Call your healthcare provider or go to the nearest emergency room right away if you have some or all of the following signs and symptoms of NMS: high fever, confusion, changes in pulse, heart rate, and blood pressure, stiff muscles, and increased sweating.</li> 2982 <li><strong>Uncontrolled body movements (tardive dyskinesia).</strong> ABILIFY MAINTENA may cause movements that you cannot control in your face, tongue, or other body parts. Tardive dyskinesia may not go away, even if you stop receiving ABILIFY MAINTENA. Tardive dyskinesia may also start after you stop receiving ABILIFY MAINTENA.</li> 2983 <li><strong>Problems with your metabolism such as:</strong> 2984 <ul> 2985 <li> 2986 <p><strong>High blood sugar (hyperglycemia) and diabetes:</strong> Increases in blood sugar can happen in some people who are treated with ABILIFY MAINTENA. Extremely high blood sugar can lead to coma or death. If you have diabetes or risk factors for diabetes such as being overweight or a family history of diabetes, your healthcare provider should check your blood sugar before you start treatment with ABILIFY MAINTENA, and during treatment.</p> 2987 </li> 2988 </ul> 2989 2990 <p class="left-indent"><strong>Call your healthcare provider if you have any of these symptoms of high blood sugar during treatment with ABILIFY MAINTENA:</strong></p> 2991 </li> 2992 </ul> 2993 2994 <ul class="left-indent"> 2995 <li> 2996 <p>feel very thirsty</p> 2997 </li> 2998 <li> 2999 <p>need to urinate more than usual</p> 3000 </li> 3001 <li> 3002 <p>feel very hungry</p> 3003 </li> 3004 <li> 3005 <p>feel weak or tired</p> 3006 </li> 3007 <li> 3008 <p>feel sick to your stomach</p> 3009 </li> 3010 <li> 3011 <p>feel confused, or your breath smells fruity</p> 3012 </li> 3013 </ul> 3014 3015 <ul class="arrow-indent"> 3016 <li><strong>Increased fat levels (cholesterol and triglycerides) in your blood.</strong></li> 3017 <li><strong>Weight gain.</strong> You and your healthcare provider should check your weight regularly during treatment.</li> 3018 </ul> 3019 3020 <ul class="symptoms-extended"> 3021 <li><strong>Unusual and uncontrollable (compulsive) urges.</strong> Some people receiving ABILIFY MAINTENA have had unusual strong urges to gamble and gambling that cannot be controlled (compulsive gambling). Other
3021compulsive urges include sexual urges, shopping, and eating or binge eating. If you or your family members notice that you are having unusual urges or behaviors, talk to your healthcare provider.</li> 3022 <li><strong>Decreased blood pressure (orthostatic hypotension).</strong> You may feel lightheaded or faint when you rise too quickly from a sitting or lying position.</li> 3023 <li><strong>Falls.</strong> ABILIFY MAINTENA may make you sleepy or dizzy, may cause a decrease in your blood pressure when changing position (orthostatic hypotension), and can slow your thinking and motor skills, which may lead to falls that can cause fractures or other injuries.</li> 3024 <li><strong>Low white blood cell count.</strong> Your healthcare provider may do blood tests during the first few months of treatment.</li> 3025 <li><strong>Seizures (convulsions)</strong></li> 3026 <li><strong>Sleepiness, drowsiness, feeling tired, difficulty thinking and doing normal activities. Do not</strong> drive a car, operate machinery, or do other dangerous activities until you know how ABILIFY MAINTENA affects you. ABILIFY MAINTENA may make you feel drowsy and affect your judgement, thinking, or motor skills.</li> 3027 <li><strong>Problems controlling your body temperature so that you feel too warm. Do not</strong> become too hot or dehydrated during treatment with ABILIFY MAINTENA. <strong>Do not</strong> exercise too much. In hot weather, stay inside in a cool place if possible. Stay out of the sun. <strong>Do not</strong> wear too much clothing or heavy clothing. Drink plenty of water.</li> 3028 <li><strong>Difficulty swallowing</strong> that can cause food or liquid to get into your lungs.</li> 3029 </ul> 3030 3031 <p class="text-high"><strong>Do not</strong> drink alcohol during treatment with ABILIFY MAINTENA.</p> 3032 3033 <p class="text-high"><strong>Before receiving ABILIFY MAINTENA, tell your healthcare provider about all your medical conditions, including if you:</strong></p> 3034 3035 <ul class="medical-conditions"> 3036 <li> 3037 <p>have never taken aripiprazole before</p> 3038 </li> 3039 <li> 3040 <p>have or had diabetes or high blood sugar or a family history of diabetes or high blood sugar</p> 3041 </li> 3042 <li> 3043 <p>have or had high levels of total cholesterol, LDL cholesterol, or triglycerides, or low levels of HDL cholesterol</p> 3044 </li> 3045 <li> 3046 <p>have or had low or high blood pressure</p> 3047 </li> 3048 <li> 3049 <p>have or had heart problems or a stroke</p> 3050 </li> 3051 <li> 3052 <p>have or had a low white blood cell count</p> 3053 </li> 3054 <li> 3055 <p>have or had seizures (convulsions)</p> 3056 </li> 3057 <li> 3058 <p>have problems that may affect you receiving an injection in your buttocks</p> 3059 </li> 3060 <li> 3061 <p>are pregnant or plan to become pregnant. ABILIFY MAINTENA may harm your unborn baby. If you become pregnant during treatment with ABILIFY MAINTENA, talk to your healthcare provider about the risk to your unborn baby and about registering with the National Pregnancy Registry for Atypical Antipsychotics. You can register by calling <a tabindex="-1" href="tel:18669612388">1-866-961-2388</a> or visit <a class="link" href="http://womensmentalhealth.org/clinical-and-research-programs/pregnancyregistry/" target="_blank">http://womensmentalhealth.org/clinical-and-research-programs/pregnancyregistry/</a></p> 3062 </li> 3063 <li> 3064 <p>are breastfeeding or plan to breastfeed. ABILIFY MAINTENA can pass into your milk and may harm your baby. Talk to your healthcare provider about the best way to feed your baby if you receive ABILIFY MAINTENA.</p> 3065 </li> 3066 </ul> 3067 3068 <p><strong>Tell your healthcare provider about all the medicines you take,</strong> including prescription medicines and over-the-counter medicines, vitamins, and herbal supplements.</p> 3069 3070 <p>ABILIFY MAINTENA and other medicines may affect each other, causing possible serious side effects. Do not start or stop any medicines during treatment with ABILIFY MAINTENA without talking to your healthcare provider first.</p> 3071 3072 <p><strong>The most common side effects of ABILIFY MAINTENA include:</strong> weight gain, restlessness or feeling like you need to move (akathisia), injection site pain, or sleepiness (sedation).</p> 3073 3074 <p>It is important to contact your healthcare provider if you experience prolonged, abnormal muscle spasms or contractions, which may be signs of a condition called dystonia.</p> 3075 3076 <p>These are not all the possible side effects of ABILIFY MAINTENA.</p> 3077 3078 <p><strong>If you have any questions about your health or medicines, talk to your healthcare provider.</strong></p> 3079 3080 <p>You are encouraged to report side effects of ABILIFY MAINTENA. Please contact Otsuka America Pharmaceutical, Inc. at <a tabindex="-1" href="tel:1-800-438-9927">1-800-438-9927</a> or FDA at <a tabindex="-1" href="tel:1-800-FDA-1088">1-800-FDA-1088</a> (<a class="link" href="https://www.fda.gov/medwatch" target="_blank">www.fda.gov/medwatch</a>).</p> 3081 </div> 3082 3083 <div class="isi-content-section"> 3084 <p>Please see <a class="link external-link-popup-disabled" href="https://www.otsuka-u
3084s.com/media/static/Abilify-M-PI.pdf" target="_blank">FULL PRESCRIBING INFORMATION</a>, including <strong>BOXED WARNING</strong>, and <a class="link external-link-popup-disabled" href="https://www.otsuka-us.com/media/static/Abilify-M-Medguide.pdf" target="_blank">MEDICATION GUIDE</a>.</p> 3085 </div> 3086</div> 3087 3088 </div> 3089 </div> 3090 3091 <!--</div>--><!--/#isi-drawer-wrapper--> 3092 3093 </section> 3094 3095 3096
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