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https://imi-rhapsody.eu/

html imi-rhapsody.eu collected 2026-10-04 18:58:24 UTC 104,291 bytes, 1,890 lines download raw bytes

1<!DOCTYPE html>
2<html lang="en">
3<head>
4
5	
6<!-- Matomo -->
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13    var u="https://sciprom-cloud.ch/matomo/";
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19
20<!-- End Matomo Code -->
21
22<!-- Social Media Cards -->
23
24
25<meta prefix="og: http://ogp.me/ns#" property="og:url" content="https://imi-rhapsody.eu/" />
26<meta prefix="og: http://ogp.me/ns#" property="og:type" content="website" />
27<meta prefix="og: http://ogp.me/ns#" property="og:title" content="RHAPSODY Project" />
28<meta prefix="og: http://ogp.me/ns#" property="og:description" content="For precision therapy and prevention of diabetes" />
29<meta prefix="og: http://ogp.me/ns#" property="og:image" content="https://imi-rhapsody.eu/rhapsody_social_cover.png" />
30 
31<meta name="twitter:card" content="summary_large_image">
32<meta name="twitter:site" content="https://imi-rhapsody.eu">
33<meta name="twitter:title" content="RHAPSODY Project">
34<meta name="twitter:description" content="For precision therapy and prevention of diabetes">
35<meta name="twitter:image" content="https://imi-rhapsody.eu/rhapsody_twitter_cover.png">
36<meta http-equiv="Content-Type" content="text/html; charset=utf-8" />
37		<meta name="robots" content="index, follow" />
38		<meta name="generator" content="RapidWeaver" />
39		
40	<meta name="twitter:card" content="summary">
41	<meta name="twitter:title" content="Rhapsody - For Precision Therapy and Prevention of Diabetes">
42	<meta name="twitter:url" content="https://imi-rhapsody.eu/index.php">
43	<meta property="og:type" content="website">
44	<meta property="og:site_name" content="Rhapsody Project Website">
45	<meta property="og:title" content="Rhapsody - For Precision Therapy and Prevention of Diabetes">
46	<meta property="og:url" content="https://imi-rhapsody.eu/index.php">
47	
48		<meta name="viewport" content="width=device-width, initial-scale=1.0">
49		<title>Rhapsody - For Precision Therapy and Prevention of Diabetes</title>
50			
51		<link rel="stylesheet" type="text/css" media="all" href="rw_common/themes/blueballfreestackresponsive/consolidated.css" />
52		
53		
54		
55		
56		
57		
58		
59		<!--script src="https://ajax.googleapis.com/ajax/libs/jquery/3.4.1/jquery.min.js"></script-->
60		
60<script type="text/javascript" src="rw_common/themes/blueballfreestackresponsive/scripts/jquery_v3.4.1.js"></script>
60
61		<!--script src="https://ajax.googleapis.com/ajax/libs/jquery/1.9.1/jquery.min.js"></script-->
62		<!--script type="text/javascript" src="rw_common/themes/blueballfreestackresponsive/scripts/jquery_v1.9.1.min.js"></script-->
63		
63<script src="rw_common/themes/blueballfreestackresponsive/scripts/fontawesome_a197540420.js" crossorigin="anonymous"></script>
63
64		
64<script type="text/javascript" src="rw_common/themes/blueballfreestackresponsive/javascript.js"></script>
64
65
66		
67		
67<script type="text/javascript">
68			var bg_01 = 'resources/body_bg01.jpg';
69			var bg_02 = 'resources/body_bg02.jpg';
70			var bg_03 = 'resources/body_bg03.jpg';
71			var bg_04 = 'resources/body_bg04.jpg';
72			var bg_05 = 'resources/body_bg05.jpg';
73			var bg_06 = 'resources/body_bg06.jpg';
74			var bg_07 = 'resources/body_bg07.jpg';
75			var bg_08 = 'resources/body_bg08.jpg';
76			var bg_09 = 'resources/body_bg09.jpg';
77			var bg_10 = 'resources/body_bg10.jpg';
78			var bg_11 = 'resources/body_bg11.png';
79			var bg_12 = 'resources/body_bg12.png';
80			var bg_13 = 'resources/body_bg13.png';
81			var bg_14 = 'resources/body_bg14.png';
82			var bg_15 = 'resources/body_bg15.png';
83			var bg_16 = 'resources/body_bg16.png';
84			var bg_17 = 'resources/body_bg17.png';
85			var bg_18 = 'resources/body_bg18.png';
86			var bg_19 = 'resources/body_bg19.png';
87			var bg_20 = 'resources/body_bg20.png';
88		</script>
88
89		
90		
90<script>
91			 $(document).ready(function() {
92  
93  $(window).scroll(function () {
94      //if you hard code, then use console
95      //.log to determine when you want the 
96      //nav bar to stick.  
97//console.log($(window).scrollTop())
98if ($(window).scrollTop() > 218) {
99	$('#bigmenu').addClass('big_fixed').removeClass('big_unfixed');
100	$('#nav_bar').addClass('nav_fixed').removeClass('nav_unfixed');
101	$('#logowrap').addClass('logo_fixed').removeClass('logo_unfixed');
102	$('#spacer').addClass('spacerbig');
103	}
104if ($(window).scrollTop() < 219) {
105	$('#bigmenu').addClass('big_unfixed').removeClass('big_fixed');
106	$('#nav_bar').addClass('nav_unfixed').removeClass('nav_fixed');
107	$('#logowrap').removeClass('logo_fixed').addClass('logo_unfixed');
108	$('#spacer').removeClass('spacerbig');
109    }
110  });
111});
112
113
114// DEFINITIONS
115
116$(document).ready(function () {
117	
118// Diabetes in a nutshell
119	$('a.item-diabetes-on').click(function() {
120	$('#definition-base').addClass('definition-box-on').removeClass('definition-box-off');
121	$('.item-body').slideUp('400');
122	$('.item-diabetes').slideDown('400');
123	$('.item-diabetes .item-body').slideDown('400');
124	$('#definition-overlay').fadeIn('600');
125	$("body").css("overflow", "hidden");
126		return false;
127	})
128	 
129// BIOMARKER
130	$('a.item-biomarker-on').click(function() {
131	$('#definition-base').addClass('definition-box-on').removeClass('definition-box-off');
132	$('.item-body').slideUp('400');
133	$('.item-biomarker').slideDown('400');
134	$('.item-biomarker .item-body').slideDown('400');
135	$('#definition-overlay').fadeIn('600');
136	$("body").css("overflow", "hidden");
137		return false;
138	})
139	
140// CDISC
141	$('a.item-cdisc-on').click(function() {
142	$('#definition-base').addClass('definition-box-on').removeClass('definition-box-off');
143	$('.item-body').slideUp('400');
144	$('.item-cdisc').slideDown('400');
145	$('.item-cdisc .item-body').slideDown('400');
146	$('#definition-overlay').fadeIn('600');
147	$("body").css("overflow", "hidden");
148		return false;
149	})
150	
151// CLINICAL TRIAL
152	$('a.item-clinical-trial-on').click(function() {
153	$('#definition-base').addClass('definition-box-on').removeClass('definition-box-off');
154	$('.item-body').slideUp('400');
155	$('.item-clinical-trial').slideDown('400');
156	$('.item-clinical-trial .item-body').slideDown('400');
157	$('#definition-overlay').fadeIn('600');
158	$("body").css("overflow", "hidden");
159		return false;
160	})
161	
162// COHORTS
163	$('a.item-cohorts-on').click(function() {
164	$('#definition-base').addClass('definition-box-on').removeClass('definition-box-off');
165	$('.item-body').slideUp('400');
166	$('.item-cohorts').slideDown('400');
167	$('.item-cohorts .item-body').slideDown('400');
168	$('#definition-overlay').fadeIn('600');
169	$("body").css("overflow", "hidden");
170		return false;
171	})
172	
173// COMPUTER SIMULATIONS
174	$('a.item-computer-simulation-on').click(function() {
175	$('#definition-base').addClass('definition-box-on').removeClass('definition-box-off');
176	$('.item-body').slideUp('400');
177	$('.item-computer-simulation').slideDown('400');
178	$('.item-computer-simulation .item-body').slideDown('400');
179	$('#definition-overlay').fadeIn('600');
180	$("body").css("overflow", "hidden");
181		return false;
182	})
183	
184// EPIGENETICS NODE
185	$('a.item-epigenetics-on').click(function() {
186	$('#definition-base').addClass('definition-box-on').removeClass('definition-box-off');
187	$('.item-body').slideUp('400');
188	$('.item-epigenetics').slideDown('400');
189	$('.item-epigenetics .item-body').slideDown('400');
190	$('#definition-overlay').fadeIn('600');
191	$("body").css("overflow", "hidden");
192		return false;
193	})
194
195// FEDERATED NODE
196	$('a.item-federated-node-on').click(function() {
197	$('#definition-base').addClass('definition-box-on').removeClass('definition-box-off');
198	$('.item-body').slideUp('400');
199	$('.item-federated-node').slideDown('400');
200	$('.item-federated-node .item-body').slideDown('400');
201	$('#definition-overlay').fadeIn('600');
202	$("body").css("overflow", "hidden");
203		return false;
204	})
205	
206// GASTRIC BYPASS
207	$('a.item-gastric-bypass-on').click(function() {
208	$('#definition-base').addClass('definition-box-on').removeClass('definition-box-off');
209	$('.item-body').slideUp('400');
210	$('.item-gastric-bypass').slideDown('400');
211	$('.item-gastric-bypass .item-body').slideDown('400');
212	$('#definition-overlay').fadeIn('600');
213	$("body").css("overflow", "hidden");
214		return false;
215	})
216
217// IMPAIRED GLUCOSE TOLERANCE
218	$('a.item-impaired-glucose-on').click(function() {
219	$('#definition-base').addClass('definition-box-on').removeClass('definition-box-off');
220	$('.item-body').slideUp('400');
221	$('.item-impaired-glucose').slideDown('400');
222	$('.item-impaired-glucose .item-body').slideDown('400');
223	$('#definition-overlay').fadeIn('600');
224	$("body").css("overflow", "hidden");
225		return false;
226	})
227	
228// INSULIN TARGET TISSUES
229	$('a.item-insulin-target-on').click(function() {
230	$('#definition-base').addClass('definition-box-on').removeClass('definition-box-off');
231	$('.item-body').slideUp('400');
232	$('.item-insulin-target').slideDown('400');
233	$('.item-insulin-target .item-body').slideDown('400');
234	$('#definition-overlay').fadeIn('600');
235	$("body").css("overflow", "hidden");
236		return false;
237	})
238
239// ONTOLOGY
240	$('a.item-ontology-on').click(function() {
241	$('#definition-base').addClass('definition-box-on').removeClass('definition-box-off');
242	$('.item-body').slideUp('400');
243	$('.item-ontology').slideDown('400');
244	$('.item-ontology .item-body').slideDown('400');
245	$('#definition-overlay').fadeIn('600');
246	$("body").css("overflow", "hidden");
247		return false;
248	})
249	
250// PRECISION MEDICINE
251	$('a.item-precision-medicine-on').click(function() {
252	$('#definition-base').addClass('definition-box-on').removeClass('definition-box-off');
253	$('.item-body').slideUp('400');
254	$('.item-precision-medicine').slideDown('400');
255	$('.item-precision-medicine .item-body').slideDown('400');
256	$('#definition-overlay').fadeIn('600');
257	$("body").css("overflow", "hidden");
258		return false;
259	})
260	
261// QALYs
262	$('a.item-qalys-on').click(function() {
263	$('#definition-base').addClass('definition-box-on').removeClass('definition-box-off');
264	$('.item-body').slideUp('400');
265	$('.item-qalys').slideDown('400');
266	$('.item-qalys .item-body').slideDown('400');
267	$('#definition-overlay').fadeIn('600');
268	$("body").css("overflow", "hidden");
269		return false;
270	})
271	
272// R
273	$('a.item-r-on').click(function() {
274	$('#definition-base').addClass('definition-box-on').removeClass('definition-box-off');
275	$('.item-body').slideUp('400');
276	$('.item-r').slideDown('400');
277	$('.item-r .item-body').slideDown('400');
278	$('#definition-overlay').fadeIn('600');
279	$("body").css("overflow", "hidden");
280		return false;
281	})
282	
283// R STUDIO DESKTOP
284	$('a.item-r-studio-on').click(function() {
285	$('#definition-base').addClass('definition-box-on').removeClass('definition-box-off');
286	$('.item-body').slideUp('400');
287	$('.item-r-studio').slideDown('400');
288	$('.item-r-studio .item-body').slideDown('400');
289	$('#definition-overlay').fadeIn('600');
290	$("body").css("overflow", "hidden");
291		return false;
292	})
293	
294// SENSITIVITY
295	$('a.item-sensitivity-on').click(function() {
296	$('#definition-base').addClass('definition-box-on').removeClass('definition-box-off');
297	$('.item-body').slideUp('400');
298	$('.item-sensitivity').slideDown('400');
299	$('.item-sensitivity .item-body').slideDown('400');
300	$('#definition-overlay').fadeIn('600');
301	$("body").css("overflow", "hidden");
302		return false;
303	})
304	
305// SPECIFICITY
306	$('a.item-specificity-on').click(function() {
307	$('#definition-base').addClass('definition-box-on').removeClass('definition-box-off');
308	$('.item-body').slideUp('400');
309	$('.item-specificity').slideDown('400');
310	$('.item-specificity .item-body').slideDown('400');
311	$('#definition-overlay').fadeIn('600');
312	$("body").css("overflow", "hidden");
313		return false;
314	})
315	
316// CLOSE TAB FROM THE BUTTON
317	
318	$('a.box_off').click(function() {
319	$('#definition-base').addClass('definition-box-off').removeClass('definition-box-on');
320	$('.item-body').slideDown('400');
321	$('.item-general').slideUp('400');
322	$('#definition-overlay').fadeOut('600');
323	$("body").css("overflow", "scroll");
324		return false;
325	})
326	
327// CLOSE TAB FROM THE OVERLAY AREA
328	
329	$('#definition-overlay').click(function() {
330	$('#definition-base').addClass('definition-box-off').removeClass('definition-box-on');
331	$('.item-body').slideDown('400');
332	$('.item-general').slideUp('400');
333	$('#definition-overlay').fadeOut('600');
334	$("body").css("overflow", "scroll");
335		return false;
336	})
337	
338// ALL EMENETS IN GLOSSARY ARE VISIBLE
339
340	$('a.reference-all').click(function() {
341	$('.item-general').slideDown('400', function() {
vendor: 11,852 bytes, lines 342-740
342	$('.item-body').slideUp('400');		
343	});
344		return false;
345	})
346	
347	
348});
349
350
351/**
352* jquery-match-height master by @liabru
353* http://brm.io/jquery-match-height/
354* License: MIT
355*/
356
357;(function(factory) { // eslint-disable-line no-extra-semi
358    'use strict';
359    if (typeof define === 'function' && define.amd) {
360        // AMD
361        define(['jquery'], factory);
362    } else if (typeof module !== 'undefined' && module.exports) {
363        // CommonJS
364        module.exports = factory(require('jquery'));
365    } else {
366        // Global
367        factory(jQuery);
368    }
369})(function($) {
370    /*
371    *  internal
372    */
373
374    var _previousResizeWidth = -1,
375        _updateTimeout = -1;
376
377    /*
378    *  _parse
379    *  value parse utility function
380    */
381
382    var _parse = function(value) {
383        // parse value and convert NaN to 0
384        return parseFloat(value) || 0;
385    };
386
387    /*
388    *  _rows
389    *  utility function returns array of jQuery selections representing each row
390    *  (as displayed after float wrapping applied by browser)
391    */
392
393    var _rows = function(elements) {
394        var tolerance = 1,
395            $elements = $(elements),
396            lastTop = null,
397            rows = [];
398
399        // group elements by their top position
400        $elements.each(function(){
401            var $that = $(this),
402                top = $that.offset().top - _parse($that.css('margin-top')),
403                lastRow = rows.length > 0 ? rows[rows.length - 1] : null;
404
405            if (lastRow === null) {
406                // first item on the row, so just push it
407                rows.push($that);
408            } else {
409                // if the row top is the same, add to the row group
410                if (Math.floor(Math.abs(lastTop - top)) <= tolerance) {
411                    rows[rows.length - 1] = lastRow.add($that);
412                } else {
413                    // otherwise start a new row group
414                    rows.push($that);
415                }
416            }
417
418            // keep track of the last row top
419            lastTop = top;
420        });
421
422        return rows;
423    };
424
425    /*
426    *  _parseOptions
427    *  handle plugin options
428    */
429
430    var _parseOptions = function(options) {
431        var opts = {
432            byRow: true,
433            property: 'height',
434            target: null,
435            remove: false
436        };
437
438        if (typeof options === 'object') {
439            return $.extend(opts, options);
440        }
441
442        if (typeof options === 'boolean') {
443            opts.byRow = options;
444        } else if (options === 'remove') {
445            opts.remove = true;
446        }
447
448        return opts;
449    };
450
451    /*
452    *  matchHeight
453    *  plugin definition
454    */
455
456    var matchHeight = $.fn.matchHeight = function(options) {
457        var opts = _parseOptions(options);
458
459        // handle remove
460        if (opts.remove) {
461            var that = this;
462
463            // remove fixed height from all selected elements
464            this.css(opts.property, '');
465
466            // remove selected elements from all groups
467            $.each(matchHeight._groups, function(key, group) {
468                group.elements = group.elements.not(that);
469            });
470
471            // TODO: cleanup empty groups
472
473            return this;
474        }
475
476        if (this.length <= 1 && !opts.target) {
477            return this;
478        }
479
480        // keep track of this group so we can re-apply later on load and resize events
481        matchHeight._groups.push({
482            elements: this,
483            options: opts
484        });
485
486        // match each element's height to the tallest element in the selection
487        matchHeight._apply(this, opts);
488
489        return this;
490    };
491
492    /*
493    *  plugin global options
494    */
495
496    matchHeight.version = 'master';
497    matchHeight._groups = [];
498    matchHeight._throttle = 80;
499    matchHeight._maintainScroll = false;
500    matchHeight._beforeUpdate = null;
501    matchHeight._afterUpdate = null;
502    matchHeight._rows = _rows;
503    matchHeight._parse = _parse;
504    matchHeight._parseOptions = _parseOptions;
505
506    /*
507    *  matchHeight._apply
508    *  apply matchHeight to given elements
509    */
510
511    matchHeight._apply = function(elements, options) {
512        var opts = _parseOptions(options),
513            $elements = $(elements),
514            rows = [$elements];
515
516        // take note of scroll position
517        var scrollTop = $(window).scrollTop(),
518            htmlHeight = $('html').outerHeight(true);
519
520        // get hidden parents
521        var $hiddenParents = $elements.parents().filter(':hidden');
522
523        // cache the original inline style
524        $hiddenParents.each(function() {
525            var $that = $(this);
526            $that.data('style-cache', $that.attr('style'));
527        });
528
529        // temporarily must force hidden parents visible
530        $hiddenParents.css('display', 'block');
531
532        // get rows if using byRow, otherwise assume one row
533        if (opts.byRow && !opts.target) {
534
535            // must first force an arbitrary equal height so floating elements break evenly
536            $elements.each(function() {
537                var $that = $(this),
538                    display = $that.css('display');
539
540                // temporarily force a usable display value
541                if (display !== 'inline-block' && display !== 'flex' && display !== 'inline-flex') {
542                    display = 'block';
543                }
544
545                // cache the original inline style
546                $that.data('style-cache', $that.attr('style'));
547
548                $that.css({
549                    'display': display,
550                    'padding-top': '0',
551                    'padding-bottom': '0',
552                    'margin-top': '0',
553                    'margin-bottom': '0',
554                    'border-top-width': '0',
555                    'border-bottom-width': '0',
556                    'height': '100px',
557                    'overflow': 'hidden'
558                });
559            });
560
561            // get the array of rows (based on element top position)
562            rows = _rows($elements);
563
564            // revert original inline styles
565            $elements.each(function() {
566                var $that = $(this);
567                $that.attr('style', $that.data('style-cache') || '');
568            });
569        }
570
571        $.each(rows, function(key, row) {
572            var $row = $(row),
573                targetHeight = 0;
574
575            if (!opts.target) {
576                // skip apply to rows with only one item
577                if (opts.byRow && $row.length <= 1) {
578                    $row.css(opts.property, '');
579                    return;
580                }
581
582                // iterate the row and find the max height
583                $row.each(function(){
584                    var $that = $(this),
585                        style = $that.attr('style'),
586                        display = $that.css('display');
587
588                    // temporarily force a usable display value
589                    if (display !== 'inline-block' && display !== 'flex' && display !== 'inline-flex') {
590                        display = 'block';
591                    }
592
593                    // ensure we get the correct actual height (and not a previously set height value)
594                    var css = { 'display': display };
595                    css[opts.property] = '';
596                    $that.css(css);
597
598                    // find the max height (including padding, but not margin)
599                    if ($that.outerHeight(false) > targetHeight) {
600                        targetHeight = $that.outerHeight(false);
601                    }
602
603                    // revert styles
604                    if (style) {
605                        $that.attr('style', style);
606                    } else {
607                        $that.css('display', '');
608                    }
609                });
610            } else {
611                // if target set, use the height of the target element
612                targetHeight = opts.target.outerHeight(false);
613            }
614
615            // iterate the row and apply the height to all elements
616            $row.each(function(){
617                var $that = $(this),
618                    verticalPadding = 0;
619
620                // don't apply to a target
621                if (opts.target && $that.is(opts.target)) {
622                    return;
623                }
624
625                // handle padding and border correctly (required when not using border-box)
626                if ($that.css('box-sizing') !== 'border-box') {
627                    verticalPadding += _parse($that.css('border-top-width')) + _parse($that.css('border-bottom-width'));
628                    verticalPadding += _parse($that.css('padding-top')) + _parse($that.css('padding-bottom'));
629                }
630
631                // set the height (accounting for padding and border)
632                $that.css(opts.property, (targetHeight - verticalPadding) + 'px');
633            });
634        });
635
636        // revert hidden parents
637        $hiddenParents.each(function() {
638            var $that = $(this);
639            $that.attr('style', $that.data('style-cache') || null);
640        });
641
642        // restore scroll position if enabled
643        if (matchHeight._maintainScroll) {
644            $(window).scrollTop((scrollTop / htmlHeight) * $('html').outerHeight(true));
645        }
646
647        return this;
648    };
649
650    /*
651    *  matchHeight._applyDataApi
652    *  applies matchHeight to all elements with a data-match-height attribute
653    */
654
655    matchHeight._applyDataApi = function() {
656        var groups = {};
657
658        // generate groups by their groupId set by elements using data-match-height
659        $('[data-match-height], [data-mh]').each(function() {
660            var $this = $(this),
661                groupId = $this.attr('data-mh') || $this.attr('data-match-height');
662
663            if (groupId in groups) {
664                groups[groupId] = groups[groupId].add($this);
665            } else {
666                groups[groupId] = $this;
667            }
668        });
669
670        // apply matchHeight to each group
671        $.each(groups, function() {
672            this.matchHeight(true);
673        });
674    };
675
676    /*
677    *  matchHeight._update
678    *  updates matchHeight on all current groups with their correct options
679    */
680
681    var _update = function(event) {
682        if (matchHeight._beforeUpdate) {
683            matchHeight._beforeUpdate(event, matchHeight._groups);
684        }
685
686        $.each(matchHeight._groups, function() {
687            matchHeight._apply(this.elements, this.options);
688        });
689
690        if (matchHeight._afterUpdate) {
691            matchHeight._afterUpdate(event, matchHeight._groups);
692        }
693    };
694
695    matchHeight._update = function(throttle, event) {
696        // prevent update if fired from a resize event
697        // where the viewport width hasn't actually changed
698        // fixes an event looping bug in IE8
699        if (event && event.type === 'resize') {
700            var windowWidth = $(window).width();
701            if (windowWidth === _previousResizeWidth) {
702                return;
703            }
704            _previousResizeWidth = windowWidth;
705        }
706
707        // throttle updates
708        if (!throttle) {
709            _update(event);
710        } else if (_updateTimeout === -1) {
711            _updateTimeout = setTimeout(function() {
712                _update(event);
713                _updateTimeout = -1;
714            }, matchHeight._throttle);
715        }
716    };
717
718    /*
719    *  bind events
720    */
721
722    // apply on DOM ready event
723    $(matchHeight._applyDataApi);
724
725    // update heights on load and resize events
726    $(window).bind('load', function(event) {
727        matchHeight._update(false, event);
728    });
729
730    // throttled update heights on resize events
731    $(window).bind('resize orientationchange', function(event) {
732        matchHeight._update(true, event);
733    });
734
735});
736
737	$(function() {
738		$('.boxybox').matchHeight({byRow: false});
739	}); 
740		</script>
740
741		
741<script src="rw_common/themes/blueballfreestackresponsive/scripts/bg/none.js"></script>
741
742		
743				<link rel='stylesheet' type='text/css' media='all' href='rw_common/plugins/stacks/stacks.css' />
744<link rel="stylesheet" type="text/css" media="all" href="rw_common/plugins/stacks/formsnap/assets/css/fs3.min.css" />		<link rel='stylesheet' type='text/css' media='all' href='files/stacks_page_page17.css' />
745        
745<script type='text/javascript' charset='utf-8' src='rw_common/plugins/stacks/jquery-2.2.4.min.js'></script>
745
746        
747        <link rel="stylesheet" href="rw_common/plugins/stacks/font-awesome.min.css">
748        
749		
750<!-- Last Modified: Mon, 28 Nov 2022 12:13:44 +0100 -->
751
752		
752<script type='text/javascript' charset='utf-8' src='files/stacks_page_page17.js'></script>
752
753		
754
755		<style type="text/css" media="all">/* FLYER BOX */
756
757.flyerbox {
758padding: 20px;
759background: #EC6553;
760color: white;
761font-size: 11pt;	
762border-radius: 5px;
763}
764
765.flyerbox  h1{
766	font-style: italic;
767text-decoration: none;	
768font-weight: 700;
769color: #ffffff!important;
770font-size: 11pt;
771padding: 10px 10px 20px 10px;
772display: block;
773margin: 0px 0px 20px 0px;
774border-bottom: 2px solid #f4f4f4;
775	
776}
777
778.flyerbox .outitem a {
779background: white;	
780color: #EC6553;
781margin-top: 15px;
782    text-decoration: none;
783    font-weight: 600;
784    transition: all ease 0.2s;
785    padding: 10px;
786    color: #EC6553;
787    width: 50%;
788    border-radius: 5px;}
789
790
791/* SYMPOSIUM */
792
793.summarybutton {
794text-align: center;	
795margin-bottom: 10px;
796}
797
798.summarybutton a {
799display: inline-block;
800padding: 4px 6px;
801background: #EC6553;	
802color: #005C97!important;
803border-radius: 3px;
804text-align: center;
805font-size: 10pt;
806font-weight: 800!important;
807text-transform: uppercase;
808transition: all ease-in 0.1s;
809}
810
811.summarybutton a:hover {
812background: #ffffff;	
813}
814
815.s-pres {
816margin-top: 10px;	
817}
818
819.s-speaker {
820	font-weight: 400;
821	opacity: 0.5;
822	font-size: 10pt;
823	}
824
825.s-line {
826display: flex;	
827flex-direction: row;
828justify-content: space-between;
829font-size: 11pt;
830font-weight: 600;
831	padding: 0px 10px 10px 10px;
832	line-height: 1.2;
833	margin-bottom: 10px;
834	border-bottom: 2px solid rgba(255,255,255,0.2);
835}
836
837
838.s-line:last-child {
839	border-bottom: 0px solid rgba(255,255,255,0.2);
840}
841
842.s-text {
843	font-size: 10pt;
844font-weight: 400;
845	padding: 0px 10px 10px 10px;
846	line-height: 1.3;
847	
848}
849
850.s-title {
851flex: 3;
852}
853
854.s-icons {
855	flex: 1;
856	display: flex;
857	justify-content: flex-end;
858	align-items: center;
859}
860
861.s-icons a {
862	color: #EC6553;	
863	font-size: 18px;
864	padding: 5px;
865	transition: all ease-in 0.1s;
866}
867
868.s-icons a:hover {
869	color: #ffffff;	
870
871}
872
873/* HEADLINES */
874
875.boxybox {
876}
877
878.boxybox_red {
879background: #EC6553;	
880border-radius: 5px;	
881font-size: 11pt;
882color: white;
883display: flex;}
884
885.boxybox_blue {
886border-radius: 5px;	
887font-size: 11pt;
888color: white;background: #005C97;	
889padding: 10px;
890}
891
892.boxybox_blue h3 {
893margin: 0px 0px 0px 0px;
894	font-style: italic;
895text-decoration: none;	
896font-weight: 700;
897color: #ffffff;
898font-size: 11pt;
899line-height: 1.2;
900padding: 10px 10px 20px 10px;
901display: block;
902margin-right: 20px;
903border-bottom: 0px solid #f4f4f4;
904}
905
906.armadilloBlogHeadlineEntry h2{
907margin: 10px 0px 10px 0px;
908border-bottom: 0px solid white;
909}
910
911.armadilloBlogHeadlineEntry h2 a{
912	font-style: italic;
913text-decoration: none;	
914font-weight: 700;
915color: #ffffff;
916font-size: 11pt;
917padding: 10px 10px 20px 10px;
918display: block;
919margin-right: 20px;
920border-bottom: 2px solid #f4f4f4;
921}
922
923.armadilloBlogHeadlineEntry {
924margin-bottom: 0px;	
925display: flex;
926flex-direction: column;
927justify-content: flex-start;
928}
929
930.feed_item_date {
931font-size: 9pt;
932color: #666!important;
933margin-top: 15px;
934font-weight: 700;
935}
936
937.armadilloBlogHeadlinePreview {
938margin: 10px 30px 10px 30px;
939display: flex;
940flex-direction: column; 
941justify-content: space-between;
942height: 100%;
943}
944
945.armadilloBlogHeadlinePreview {
946display: flex;
947flex-direction: column;}
948
949.armadilloBlogHeadlinePreview a{
950margin-top: 15px;
951background: #ffffff;
952text-decoration: none;
953font-weight: 600;
954transition: all ease 0.2s;
955display: flex;
956padding: 10px;
957color: #EC6553;
958border-radius: 5px;
959width: 50%
960}
961
962.armadilloBlogHeadlinePreview a:hover{
963	width: 55%;
964}
965
966
967
968/* SUBMENU OUTCOMES */
969
970.submenuoutcomes {
971display: none;	
972}
973	
974/* DEFINITION TEXT */
975
976a.definition {
977box-shadow: 0px 0px 0px 0px rgba(236,101,83,0.3) inset;	
978transition: all ease-in 0.1s;
979color: #333333!important;
980display: inline-block;
981border-radius: 5px 15px 15px 5px;
982}
983
984a.definition:after {
985content: "?";
986background: rgba(236,101,83,0.3);
987color: white;
988font-size: 10pt;
989font-weight: 800;
990padding: 2px 6px;
991margin-left: 2px;
992border-radius: 50%;
993transition: all ease-in 0.3s;
994}
995
996a.definition:hover {
997box-shadow: -200px 0px 0px 0px rgba(236,101,83,0.3) inset;
998}
999
1000a.definition:hover:after {
1001background: rgba(236,101,83,1);
1002transition: all ease-in 0.0s;
1003}
1004
1005/* DEFINIION BLOCK */
1006
1007#definition-overlay {
1008position: fixed;
1009background: rgba(255,255,255,0.6);
1010width: 100%;
1011height: 100%;	
1012z-index: 1000;
1013top: 0px;
1014left: 0px;
1015overflow: hidden;
1016box-sizing: border-box;
1017z-index: 1000000;
1018display: none;
1019}
1020
1021.definition-box {
1022position: fixed;
1023background: rgba(255,255,255,1);
1024width: 40%;
1025height: 100%;	
1026z-index: 1000;
1027top: 0px;
1028left: 0px;
1029overflow: scroll;
1030box-sizing: border-box;
1031box-shadow: 0px 0px 30px 0px rgba(0,0,0,0.1);
1032z-index: 1000001;
1033}
1034
1035@media screen and (max-width: 740px) {
1036.definition-box {
1037width: 90%;}
1038}
1039
1040.definition-box-off {
1041margin-left: -90%;	
1042transition: all ease-in 0.2s;
1043}
1044
1045.definition-box-on {
1046margin-left: 0%;
1047transition: all ease-in 0.2s;
1048
1049}
1050
1051.definition-close {
1052float: right;
1053}
1054
1055.definition-close a {
1056background: #EC6553;
1057display: inline-block;
1058padding: 5px;
1059border-radius: 5px;
1060color: white!important;	
1061text-transform: uppercase;
1062font-weight: 700;
1063}
1064
1065.definition-box-in {
1066	padding: 30px;
1067	font-size: 11pt;
1068	line-height: 1.3;
1069	box-sizing: border-box;
1070	font-weight: 500;
1071}
1072
1073.reference-topic a{
1074font-weight: 700;
1075color: #999!important;	
1076display: inline-block;
1077padding: 5px 5px 5px 0px;
1078}
1079
1080.reference-topic a:after {
1081content: "» see all";
1082margin-left: -10px;
1083opacity: 0;
1084transition: all ease-in 0.1s;
1085}
1086
1087.reference-topic a:hover:after {
1088margin-left: 5px;
1089opacity: 1;
1090transition: all ease-in 0.1s;
1091}
1092
1093
1094.item-title a{
1095font-size: 13pt;
1096font-style: italic;
1097font-weight: 600;
1098color: #005C97;
1099margin-top: 0px;
1100margin-bottom: 10px;
1101border-bottom: 2px solid #005C97;
1102padding-bottom: 5px;
1103display: block;
1104}
1105
1106.item-title a:before {
1107content: "»";
1108margin-right: 10px;
1109margin-left: 0px;
1110transition: all ease-in 0.1s;
1111}
1112
1113.item-title a:hover:before {
1114content: "»";
1115margin-right: 5px;
1116margin-left: 5px;
1117}
1118
1119.item-general {
1120display: none;	
1121}
1122
1123.item-body {
1124margin-bottom: 10px;	
1125}
1126
1127
1128/* FINAL RESULTS */
1129
1130
1131
1132
1133.final_menu {
1134background: #f4f4f4;
1135padding: 85px 10px 10px 10px;	
1136border-radius: 0px 0px 5px 5px;
1137}
1138
1139.final_menu_in {
1140display: flex;
1141flex-direction: row;
1142justify-content: flex-start;	
1143align-items: stretch;
1144}
1145
1146.general_item, .menu_item  {
1147flex: 1;
1148display: flex;
1149flex-direction: row;
1150justify-content: flex-start;	
1151align-items: stretch;
1152font-size: 10pt;
1153text-align: center;
1154}
1155
1156.general_item a{
1157color: #999!important;
1158font-weight: 600;
1159text-decoration: none;
1160display: block;
1161padding: 5px;
1162width: 100%;
1163transition: all ease-in 0.1s;
1164}
1165
1166.general_item a:hover {
1167color: #666!important;
1168}
1169
1170.menu_item a{
1171	background: #999;
1172	color: white!important;
1173	display: block;
1174font-weight: 600;
1175text-decoration: none;
1176padding: 5px;
1177border-radius: 5px;
1178width: 100%;
1179transition: all ease-in 0.1s;
1180}
1181
1182.menu_item a:hover{
1183	background: #666;
1184}
1185
1186.menu_item {
1187margin-right: 10px;	
1188}
1189
1190.menu_item:last-child {
1191	margin-right: 0px;
1192}
1193
1194.replay_gif {
1195	text-align: center;
1196	font-style: italic;
1197	animation: fadeIn ease 12s;
1198}
1199
1200@keyframes fadeIn {
12010% {opacity:0;}
120290% {opacity:0;}
1203100% {opacity:1;}
1204}
1205
1206
1207.lefthead {
1208font-size: 18pt;
1209line-height: 1.1em;
1210font-style: italic;
1211width: 50%;
1212font-weight: 800;
1213color: #005C97;	
1214margin: 50px 0px 0px 0px;
1215padding: 0px 20px;
1216border-bottom: 2px solid #f4f4f4;
1217padding-bottom: 30px;
1218}
1219
1220.feature_text {
1221font-size: 12pt;
1222font-weight: 600;
1223margin: 30px 0px 30px 0px;
1224padding: 0px 20px;
1225}
1226
1227.quote {
1228
1229	margin-top: 20px;
1230font-size: 14pt;
1231line-height: 1.1;
1232font-style: italic;
1233width: 100%;
1234font-weight: 700;
1235color: #333;	
1236margin-bottom: 70px;
1237padding: 0px 20px;	
1238text-align: left;
1239}
1240
1241/*.quote::before {
1242content: "}";
1243position: absolute;
1244top: -50px;
1245margin-left: 0px;
1246font-size: 100pt;
1247opacity: 1;
1248color: #EC6553;
1249font-weight: 400;
1250}*/
1251
1252
1253
1254/* END FINAL RESULTS */
1255
1256
1257
1258h1 {
1259color: #005C97!important;
1260}
1261
1262a {
1263    color: #005C97;
1264    text-decoration: none!important;
1265}
1266
1267p a {
1268	    color: #005C97!important;
1269}
1270
1271#nav_bar li a {
1272}
1273
1274#bigmenu {
1275background: transparent url('resources/banner_2.jpg')  50% -40px;	
1276}
1277
1278
1279#pagecontainer {
1280}
1281
1282.strike {
1283text-decoration: line-through;	
1284}
1285
1286
1287/* QUOTES */
1288
1289.quoteFG {
1290	font-weight: 700;
1291font-style: italic;
1292font-size: 10pt;
1293background: #B81D3C;
1294color: #fff;	
1295padding: 20px 20px 10px 20px;
1296border-radius: 5px 5px 0px 0px;
1297}
1298
1299.quoteFG1 {
1300	font-weight: 700;
1301text-align: right;
1302font-size: 10pt;
1303background: #B81D3C;
1304color: #fff;	
1305padding: 10px 20px 20px 20px;
1306border-radius: 0px 0px 5px 5px;
1307}
1308
1309</style>
1310	</head>
1311	
1312	<!-- This page was created using the Blueball FreeStack Responsive theme v2.3 -->
1313	
1314	<body>
1315	
1316	<div id="pagecontainer">
1317		<div id="pagewrapper" class="basic">
1318			<div id="spacer"></div>
1319			<div id="bigmenu" class="big_unfixed">
1320				<div id="menuButton"><i class="fa fa-bars" aria-hidden="true"></i></div>
1321				<div id="members"><a href="https://imi-rhapsody.eu/members/">
1322					<div id="memberino">Members section</div>
1323					<i class="fa fa-key" aria-hidden="true"></i>
1324					</a>
1325				</div>
1326								<div id="searchbutton"><a href="https://imi-rhapsody.eu/search/"><i class="fas fa-search"></i></a></div>
1327
1328				<!--<div id="jobs"><a href="#" onclick="$('#jobber').slideToggle('slow');return false;">Jobs</a></div>-->
1329				<div id="logowrap" class="logo_unfixed"></div><div id="cercami"></div>
1330				<div id="nav_bar" class="nav_unfixed">
1331				<ul><li><a href="./" rel="" id="current">Home</a></li><li><a href="outcomes/" rel="">Outcomes</a></li><li><a href="publications/" rel="">Publications</a></li><li><a href="consortium/" rel="">Consortium</a></li><li><a href="news/" rel="">News</a></li><li><a href="final-symposium/" rel="">Final symposium</a></li></ul>
1332				</div>
1333			</div>	
1334							<div class="submenuoutcomes">
1335							<div class="submenuoutcomes-in">
1336							<div class="item-outcomes"><a href="https://imi-rhapsody.eu/outcomes/federated-database"><div class="item-outcomes-subelement"><div class="item-outcomes-subelement-in mini-icon"><img src="resources/icona_database_blue.svg" /></div><div class="item-outcomes-subelement-in">Federated Database</div></div></a></div>
1337							
1338							<div class="item-outcomes"><a href="https://imi-rhapsody.eu/outcomes/clustering-biomarkers"><div class="item-outcomes-subelement"><div class="item-outcomes-subelement-in mini-icon"><img src="resources/icona_biomarker_blue.svg" /></div><div class="item-outcomes-subelement-in">Clustering & biomarkers</div></div></a></div>
1339
1340							<div class="item-outcomes"><a href="https://imi-rhapsody.eu/outcomes/organ-dysfunction"><div class="item-outcomes-subelement"><div class="item-outcomes-subelement-in mini-icon"><img src="resources/icona_dysfunction_blue.svg" /></div><div class="item-outcomes-subelement-in">Organ dysfunction</div></div></a></div>
1341
1342							<div class="item-outcomes"><a href="https://imi-rhapsody.eu/outcomes/regulatory-economics"><div class="item-outcomes-subelement"><div class="item-outcomes-subelement-in mini-icon"><img src="resources/icona_regulatory_blue.svg" /></div><div class="item-outcomes-subelement-in">Regulatory & economics</div></div></a></div>
1343
1344							</div>
1345							</div>
1346
1347	
1348<div id='stacks_out_1' class='stacks_top'><div id='stacks_in_1' class=''><div   class="lefthead" style=""> <div id='stacks_out_6914' class='stacks_out'><div id='stacks_in_6914' class='stacks_in text_stack'>For precision therapy and prevention of diabetes</div></div></div>
1349
1350<div id='stacks_out_6906' class='stacks_out'><div id='stacks_in_6906' class='stacks_in html_stack'><img id="gif-1" src="resources/project-animation1.gif" alt="animated gif" width="100%" height="auto"/>
1351<div class="replay_gif">
1352    <a href="#" 
1353      onclick="document.getElementById('gif-1').src='resources/project-animation1.gif'">
1354     Click to replay</a>
1355  </div></div></div><div   class="feature_text" style=""> <div id='stacks_out_6918' class='stacks_out'><div id='stacks_in_6918' class='stacks_in text_stack'><p><a class="definition item-diabetes-on" href="#">Type 2 diabetes</a> currently impacts the lives of some 400 million people worldwide. It is already <a href="https://www.researchgate.net/publication/262042041_Type_2_Diabetes_Mellitus_Pandemic_in_21st_Century" target="_blank">considered as a global epidemic</a> due to the constant increase in the number of patients and the challenges faced by families, partners and caregivers. </p>Unfortunately, the effectiveness of current therapies varies considerably between individuals. Using <a class="definition item-precision-medicine-on" href="#">precision medicine</a> approaches that take into account the patient's biological characteristics can optimise disease prevention and treatment, thereby improving overall prognosis and reducing costs and side effects.</p><p><a href="https://www.who.int/news-room/fact-sheets/detail/diabetes" target="_blank">As supported by the World Health Organisation</a>, &ldquo;effective measures for the surveillance, prevention and control of diabetes and its complications&rdquo; need be developed. This is where RHAPSODY came in.</p></div></div></div>
1356
1357<div id='stacks_out_7029' class='stacks_out'><div id='stacks_in_7029' class='stacks_in stack_stack'><div id='stacks_out_7019' class='stacks_out'><div id='stacks_in_7019' class='stacks_in com_yourhead_stacks_three_columns_stack'><div class='s3_row'>
1358	<div class='s3_column s3_column_left'><div id='stacks_out_7023' class='stacks_out'><div id='stacks_in_7023' class='stacks_in com_nimblehost_stack_armadilloBlogHeadlines_stack in boxybox_red boxybox'>
1359<div class="armadilloBlogHeadlines_2 armadilloBlogHeadlines armadilloContent">
1360<div class="armadilloBlogHeadlineEntry"><h2><a href="https://imi-rhapsody.eu/news/?post_id=44&title=rhapsody-final-consortium-meeting">RHAPSODY Final Consortium meeting</a></h2><div class="armadilloBlogHeadlinePreview" style="padding-bottom: 15px;font-size: 1.0em;">Today starts&nbsp;our final consortium meeting, a two days hybrid meeting&nbsp;concluding 5 incredible years with amazing results. To learn <a href="https://imi-rhapsody.eu/news/?post_id=44&title=rhapsody-final-consortium-meeting">» Read more</a></div></div></div>
1361
1362
1363</div></div></div>
1364	<div class='s3_column s3_column_center'><div id='stacks_out_7145' class='stacks_out'><div id='stacks_in_7145' class='stacks_in stack_stack in boxybox_blue boxybox'><div id='stacks_out_7146' class='stacks_out'><div id='stacks_in_7146' class='stacks_in com_yourhead_stack_header_stack'><h3>Watch Mark Ibberson talking about our innovative Federated Database and its development</h3></div></div><div id='stacks_out_7175' class='stacks_out'><div id='stacks_in_7175' class='stacks_in site_image_stack'>
1365
1366<a href="#" class="expose_video-v1"><img class='imageStyle stacksImage' src='resources/mark_play.png' alt='Stacks Image 7177' /></a>
1367
1368</div></div></div></div></div>
1369	<div class='s3_column s3_column_right'><div id='stacks_out_7075' class='stacks_out'><div id='stacks_in_7075' class='stacks_in stack_stack in boxybox_blue boxybox'><div id='stacks_out_7081' class='stacks_out'><div id='stacks_in_7081' class='stacks_in com_yourhead_stack_header_stack'><h3>Watch our video "A unique and multidisciplinary public-private collaboration"</h3></div></div><div id='stacks_out_7178' class='stacks_out'><div id='stacks_in_7178' class='stacks_in site_image_stack'>
1370
1371<a href="#" class="expose_video-v2"><img class='imageStyle stacksImage' src='resources/imi_play.png' alt='Stacks Image 7180' /></a>
1372
1373</div></div></div></div></div>
1374</div></div></div></div></div><div   class="lefthead" style=""> <div id='stacks_out_6921' class='stacks_out'><div id='stacks_in_6921' class='stacks_in text_stack'>Biomarkers as a tool to assess the individual risk and progression of type 2 diabetes</div></div></div>
1375
1376<div   class="feature_text" style=""> <div id='stacks_out_6925' class='stacks_out'><div id='stacks_in_6925' class='stacks_in text_stack'><p>Currently, risk and diagnosis of type 2 diabetes are confirmed by testing blood sugar levels. Hence, blood glucose acts as a <a class="definition item-biomarker-on" href="#">&lsquo;biomarker&rsquo;</a> for the risk and presence of diabetes. In RHAPSODY, it is our aim to identify novel biomarkers, other than blood glucose, that can be used to identify individuals most at risk of developing type 2 diabetes, and predict its individual clinical course (disease progression) and its complications.</p></div></div><div id='stacks_out_6982' class='stacks_out'><div id='stacks_in_6982' class='stacks_in html_stack'><img src="resources/project-animation2.gif"  width="100%" height="auto"/></div></div></div>
1377
1378<div id='stacks_out_7083' class='stacks_out'><div id='stacks_in_7083' class='stacks_in com_yourhead_stacks_two_columns_stack'><div class='s3_row'>
1379	<div class='s3_column s3_column_left'><div id='stacks_out_7001' class='stacks_out'><div id='stacks_in_7001' class='stacks_in text_stack'><p>Importantly, type 2 diabetes is a highly heterogeneous disease, leading to various degrees of deficient insulin production, and/or insulin resistance and finally hyperglycemia. The heterogeneous nature of type 2 diabetes in patients makes it difficult to determine the most efficient treatment for a given patient, as patients often respond differently to the same treatment. </p><p>In this context, the characterization of groups of individual patients whose diabetes behaves similarly (so-called &ldquo;patient clustering&rdquo;) and the identification of novel biomarkers specific to these groups are of great importance for tailored diagnosis and disease monitoring for the individual patients. This is the first step towards precision medicine in type 2 diabetes: by enabling this step 
1379so, RHAPSODY aims at improving overall prognosis.</p></div></div><div   class="lefthead" style=""> <div id='stacks_out_6928' class='stacks_out'><div id='stacks_in_6928' class='stacks_in text_stack'>Our approach to identify novel biomarkers for Precision Therapy and Prevention of Diabetes</div></div></div>
1380
1381<div   class="feature_text" style=""> <div id='stacks_out_6969' class='stacks_out'><div id='stacks_in_6969' class='stacks_in text_stack'><p>In RHAPSODY, we had access to data from large groups of patients from across Europe (<a class="definition item-cohorts-on" href="#">study cohorts</a>, learn more about <a href="outcomes/federated-database/" title="Federated Database">RHAPSODY cohorts here</a>), including individual clinical, biochemical, genetic and multi-omics data (discover more about <a href="outcomes/clustering-biomarkers/" title="Clustering and biomarkers">the omics here</a>). We combine powerful bioinformatics analysis and various experimental approaches, using blood samples and key diabetes-relevant tissues and organs from humans and mouse preclinical models (<a href="outcomes/organ-dysfunction/" title="Deciphering organ dysfunction">learn more here</a>) to identify novel biomarkers for type 2 diabetes susceptibility and progression for individual patients, as well as to clarify their link with the alterations of pancreatic insulin secretion and of insulin action on liver, fat and muscle. </p><p>In order to validate the novel biomarkers identified in RHAPSODY for clinical use and pharmacological applications, experts in regulatory approval supported scientists in ensuring that biomarker characterization and development are in line and further developed with the requirements by the European Medicines Agency (EMA). Health economists performed cost-benefit assessments, ensuring that the discovery process of RHAPSODY minimizes the time between biomarker identification and their potential clinical and commercial use (more information <a href="outcomes/regulatory-economics/" title="Regulatory and economics">available here</a>).</p></div></div></div>
1382
1383</div>
1384	<div class='s3_column s3_column_right'><div id='stacks_out_7090' class='stacks_out'><div id='stacks_in_7090' class='stacks_in stack_stack in boxybox_blue '><div id='stacks_out_7091' class='stacks_out'><div id='stacks_in_7091' class='stacks_in com_yourhead_stack_header_stack'><h3>RHAPSODY Final Symposium — Biomarkers for precision therapy and prevention of type 2 diabetes</h3></div></div><div id='stacks_out_7151' class='stacks_out'><div id='stacks_in_7151' class='stacks_in text_stack in s-text'>On 17 September 2021, the RHAPSODY team shared its achievements with patient and healthcare communities at a half-day symposium.</div></div><div id='stacks_out_7098' class='stacks_out'><div id='stacks_in_7098' class='stacks_in html_stack'><div class="s-pres"> 
1385 
1386	<div class="s-line">
1387		<div class="s-title">
1388		Welcome
1389		<div class="s-speaker">Bernard Thorens</div>
1390		</div>
1391		<div class="s-icons">
1392		<div class="s-video">
1393		<a href="#" class="expose_video-p1"><i class="fas fa-play-circle"></i></a>
1394		</div>
1395		</div>
1396	</div>
1397
1398<div class="s-line">
1399		<div class="s-title">
1400		Diabetes care: a clinician`s point of view
1401		<div class="s-speaker">Andreas Festa</div>
1402		</div>
1403		<div class="s-icons">
1404		<div class="s-slides">
1405		<a href="resources/finalsymposium/RHAPSODY_Final-Symposium_Festa-forWebsite_v1.0.pdf" target="_blank"><i class="fas fa-file-alt"></i></a>
1406		</div>
1407		<div class="s-video">
1408		<a href="#" class="expose_video-p2"><i class="fas fa-play-circle"></i></a>
1409		</div>
1410		</div>
1411	</div>
1412
1413
1414<div class="s-line">
1415		<div class="s-title">
1416		Diabetes care: a patient's perspective
1417		<div class="s-speaker">Elizabeth Robertson</div>
1418		</div>
1419		<div class="s-icons">
1420		<div class="s-slides">
1421		<a href="resources/finalsymposium/RHAPSODY_Final-Symposium_Robertson_v1.0.pdf" target="_blank"><i class="fas fa-file-alt"></i></a>
1422		</div>
1423		<div class="s-video">
1424		<a href="#" class="expose_video-p3"><i class="fas fa-play-circle"></i></a>
1425		</div>
1426		</div>
1427	</div>
1428
1429
1430<div class="s-line">
1431		<div class="s-title">
1432		What does the Innovative Medicines Initiative do to help patients with diabetes?
1433		<div class="s-speaker">Claire Varin</div>
1434		</div>
1435		<div class="s-icons">
1436		<div class="s-slides">
1437		<a href="resources/finalsymposium/RHAPSODY_Final-Symposium_Varin_forWebsite.pdf" target="_blank"><i class="fas fa-file-alt"></i></a>
1438		</div>
1439		<div class="s-video">
1440		<a href="#" class="expose_video-p4"><i class="fas fa-play-circle"></i></a>
1441		</div>
1442		</div>
1443	</div>
1444
1445
1446<div class="s-line">
1447		<div class="s-title">
1448		The RHAPSODY project: Biomarkers in type 2 diabetes 
1449		<div class="s-speaker">Bernard Thorens</div>
1450		</div>
1451		<div class="s-icons">
1452		<div class="s-slides">
1453		<a href="resources/finalsymposium/RHAPSODY_Final-Symposium_Thorens_v1.0.pdf" target="_blank"><i class="fas fa-file-alt"></i></a>
1454		</div>
1455		<div class="s-video">
1456		<a href="#" class="expose_video-p5"><i class="fas fa-play-circle"></i></a>
1457		</div>
1458		</div>
1459	</div>
1460
1461
1462<div class="s-line">
1463		<div class="s-title">
1464		A new diabetes patient sub-classification: what's next?
1465		<div class="s-speaker">Emma Ahlqvist</div>
1466		</div>
1467		<div class="s-icons">
1468		<div class="s-slides">
1469		<a href="resources/finalsymposium/RHAPSODY_Final-Symposium_Ahlqvist_v1.0.pdf" target="_blank"><i class="fas fa-file-alt"></i></a>
1470		</div>
1471		<div class="s-video">
1472		<a href="#" class="expose_video-p6"><i class="fas fa-play-circle"></i></a>
1473		</div>
1474		</div>
1475	</div>
1476
1477
1478<div class="s-line">
1479		<div class="s-title">
1480		A new diabetes patient sub-classification: its application in RHAPSODY
1481		<div class="s-speaker">Roderick Slieker</div>
1482		</div>
1483		<div class="s-icons">
1484		<div class="s-slides">
1485		<a href="resources/finalsymposium/RHAPSODY_Final-Symposium_Slieker_v1.0.pdf" target="_blank"><i class="fas fa-file-alt"></i></a>
1486		</div>
1487		<div class="s-video">
1488		<a href="#" class="expose_video-p7"><i class="fas fa-play-circle"></i></a>
1489		</div>
1490		</div>
1491	</div>
1492
1493
1494<div class="s-line">
1495		<div class="s-title">
1496		Panel discussion "Why does it matter?"
1497		<div class="s-speaker">Moderator: Andreas Festa
1498		</div>
1499		</div>
1500		<div class="s-icons">
1501		<div class="s-video">
1502		<a href="#" class="expose_video-p8"><i class="fas fa-play-circle"></i></a>
1503		</div>
1504		</div>
1505	</div>
1506
1507
1508<div class="s-line">
1509		<div class="s-title">
1510		Wrap-up and conclusions
1511		<div class="s-speaker">Claire Varin, Bernard Thorens</div>
1512		</div>
1513		<div class="s-icons">
1514		<div class="s-video">
1515		<a href="#" class="expose_video-p9"><i class="fas fa-play-circle"></i></a>
1516		</div>
1517		</div>
1518	</div>
1519
1520
1521</div>
1522</div></div><div   class="summarybutton" style=""> <a href="resources/RHAPSODY_FinalSymposium_Summary_v1.1.pdf" target="_blank" class="block-link"> <div id='stacks_out_7162' class='stacks_out'><div id='stacks_in_7162' class='stacks_in text_stack'>Download the summary</div></div> </a> 
1523</div>
1524
1525</div></div></div>
1526</div></div></div><div id='stacks_out_6999' class='stacks_out'><div id='stacks_in_6999' class='stacks_in html_stack'><img src="resources/project-animation3.gif"  width="100%" height="auto"/></div></div><div id='stacks_out_6997' class='stacks_out'><div id='stacks_in_6997' class='stacks_in '><div  id="definition-overlay"  class="" style=""> <div class='slice empty out'><div class='slice empty in'></div></div></div>
1527
1528<div  id="definition-base"  class="definition-box definition-box-off" style=""> <div   class="definition-box-in" style=""> <div   class="definition-close" style=""> <a href="#" class="box_off block-link"> <div id='stacks_out_6997_10' class='stacks_out'><div id='stacks_in_6997_10' class='stacks_in text_stack'>Close <i class="far fa-times-circle"></i></div></div> </a> 
1529</div>
1530
1531<div id='stacks_out_6997_12' class='stacks_out'><div id='stacks_in_6997_12' class='stacks_in html_stack'><div class="reference-topic">
1532<a href="#" class="reference-all">RHAPSODY Reference</a>
1533</div></div></div><div id='stacks_out_6997_46' class='stacks_out'><div id='stacks_in_6997_46' class='stacks_in stack_stack in item-biomarker item-general'><div id='stacks_out_6997_47' class='stacks_out'>
1533<div id='stacks_in_6997_47' class='stacks_in html_stack in item-title'><a href="#" class="item-biomarker-on">Biomarker</a></div></div><div id='stacks_out_6997_50' class='stacks_out'><div id='stacks_in_6997_50' class='stacks_in text_stack in item-body'><p>A biomarker can be any naturally occurring molecule (protein, lipids, DNA, RNA etc.) found in human tissues or blood stream, which is a measurable characteristic that indicates a normal biologic process, a pathogenic process, and/or a response to therapeutic interventions (Source: <a href="https://www.ema.europa.eu/en/documents/scientific-guideline/ich-e-15-establish-definitions-genomic-biomarkers-pharmacogenomics-pharmacogenetics-genomic-data_en.pdf" target="_blank">ICH</a>)</p></div></div></div></div><div id='stacks_out_6997_58' class='stacks_out'><div id='stacks_in_6997_58' class='stacks_in stack_stack in item-cdisc item-general'><div id='stacks_out_6997_59' class='stacks_out'><div id='stacks_in_6997_59' class='stacks_in html_stack in item-title'><a href="#" class="item-cdisc-on">CDISC</a></div></div><div id='stacks_out_6997_62' class='stacks_out'><div id='stacks_in_6997_62' class='stacks_in text_stack in item-body'><p><a href="https://cdisc.org/" target="_blank">Clinical Data Interchange Standards Consortium</a>. A set of widely used standards for clinical data.</p></div></div></div></div><div id='stacks_out_6997_76' class='stacks_out'><div id='stacks_in_6997_76' class='stacks_in stack_stack in item-clinical-trial item-general'><div id='stacks_out_6997_77' class='stacks_out'><div id='stacks_in_6997_77' class='stacks_in html_stack in item-title'><a href="#" class="item-clinical-trial-on">Clinical trial</a></div></div><div id='stacks_out_6997_80' class='stacks_out'><div id='stacks_in_6997_80' class='stacks_in text_stack in item-body'><p>A research study in which one or more human subjects are prospectively assigned to one or more interventions (which may include placebo or other control) to evaluate the effects of those interventions on health-related biomedical or behavioral outcomes (source: <a href="https://grants.nih.gov/" target="_blank">https://grants.nih.gov/</a>).</p></div></div></div></div><div id='stacks_out_6997_40' class='stacks_out'><div id='stacks_in_6997_40' class='stacks_in stack_stack in item-cohorts item-general'><div id='stacks_out_6997_41' class='stacks_out'><div id='stacks_in_6997_41' class='stacks_in html_stack in item-title'><a href="#" class="item-cohorts-on">Cohorts</a></div></div><div id='stacks_out_6997_44' class='stacks_out'><div id='stacks_in_6997_44' class='stacks_in text_stack in item-body'><p>Patient cohort: A group of individuals affected by common diseases, environmental or temporal influences, treatments, or other traits whose progress is assessed in a research study (source: <a href="https://medical-dictionary.thefreedictionary.com/" target="_blank">https://medical-dictionary.thefreedictionary.com/</a>) </p></div></div></div></div><div id='stacks_out_6997_125' class='stacks_out'><div id='stacks_in_6997_125' class='stacks_in stack_stack in item-computer-simulation item-general'><div id='stacks_out_6997_126' class='stacks_out'><div id='stacks_in_6997_126' class='stacks_in html_stack in item-title'><a href="#" class="item-computer-simulation-on">Computer simulation models	</a></div></div><div id='stacks_out_6997_129' class='stacks_out'><div id='stacks_in_6997_129' class='stacks_in text_stack in item-body'><p>Computer simulation models are a common tool to predict how different treatments may affect disease progression and outcomes. They are used to extrapolate the findings of clinical trials into lifetime costs and health benefits. </p></div></div></div></div><div id='stacks_out_6997_34' class='stacks_out'><div id='stacks_in_6997_34' class='stacks_in stack_stack in item-diabetes item-general'><div id='stacks_out_6997_35' class='stacks_out'><div id='stacks_in_6997_35' class='stacks_in html_stack in item-title'><a href="#" class="item-diabetes-on">Diabetes in a nutshell</a></div></div><div id='stacks_out_6997_38' class='stacks_out'>
1533<div id='stacks_in_6997_38' class='stacks_in text_stack in item-body'><p>Diabetes is a chronic disease characterised by chronically elevated levels of blood sugar (hyperglycemia), due to alterations in the production or the use of insulin by the body. Insulin action is vital to ensure that glucose (sugar, basic source of energy) from our food is properly utilised by cells of the human body. </p><p>Insulin is a hormone produced by the pancreas (more precisely by pancreatic beta cells), which is crucial to control blood glucose (glycemia). Once secreted into the blood stream, insulin orchestrates a coordinated response to lower blood glucose by acting on several tissues (namely <a href="#" class="item-insulin-target-on">insulin-target tissues</a>). Notably, insulin stimulates glucose uptake by muscle and fat (adipose tissue) and prevents glucose production by the liver. </p><p>For a long time, diabetes has been labelled either &lsquo;type 1&rsquo; or &lsquo;type 2&rsquo; diabetes. Type 2 diabetes is the result of failures across several complex biological systems. Compared to those with type 1 diabetes, patients with type 2 diabetes can still produce insulin, at least during the first stages of the disease (prediabetes and early type 2 diabetes). However, their insulin-target tissues stop responding to the normal amounts of insulin produced after eating: this so-called &ldquo;insulin resistance&rdquo; process prevents glucose uptake by cells, resulting in rise of blood glucose. Chronic hyperglycemia tricks the pancreas into over-producing insulin. If untreated, this vicious circle of events can spiral out of control leading to an exhaustion of the pancreas (&ldquo;pancreatic beta cell failure&rdquo;) to produce insulin (insulin deficiency).</p><p>Diabetes is a major public health problem since over time, it can damage heart and blood vessels (heart attacks and strokes), nerves (neuropathy resulting in foot ulcers and possibly limb amputation), eyes (retinopathy leading to blindness) and kidneys (nephropathy). </p><br /></div></div></div></div><div id='stacks_out_6997_14' class='stacks_out'><div id='stacks_in_6997_14' class='stacks_in stack_stack in item-epigenetics item-general'><div id='stacks_out_6997_16' class='stacks_out'><div id='stacks_in_6997_16' class='stacks_in html_stack in item-title'><a href="#" class="item-epigenetics-on">Epigenetics</a></div></div><div id='stacks_out_6997_18' class='stacks_out'><div id='stacks_in_6997_18' class='stacks_in text_stack in item-body'><p>Epigenetics is the study of how behaviors and environment can cause changes that affect the way genes work. Unlike genetic changes, epigenetic changes are reversible and do not change DNA sequence, but they can change how the body reads a DNA sequence (source: <a href="https://www.cdc.gov/genomics/disease/epigenetics.htm" target="_blank">https://www.cdc.gov/genomics/disease/epigenetics.htm</a>).</p></div></div></div></div><div id='stacks_out_6997_143' class='stacks_out'><div id='stacks_in_6997_143' class='stacks_in stack_stack in item-Elovl2 item-general'><div id='stacks_out_6997_144' class='stacks_out'><div id='stacks_in_6997_144' class='stacks_in html_stack in item-title'><a href="#" class="item-Elovl2-on">Elovl2</a></div></div><div id='stacks_out_6997_147' class='stacks_out'><div id='stacks_in_6997_147' class='stacks_in text_stack in item-body'><p>Elovl2: this gene encodes for the protein called "Elongation of very long chain fatty acids protein 2" which catalyzes the first and rate-limiting reaction of the four reactions that constitute the long-chain fatty acids elongation cycle. This endoplasmic reticulum-bound enzymatic process allows the addition of 2 carbons to the chain of long- and very long-chain fatty acids (VLCFAs) per cycle (source: <a href="https://www.uniprot.org/uniprot/Q9JLJ4" target="_blank">https://www.uniprot.org/uniprot/Q9JLJ4</a>)</p></div></div></div></div><div id='stacks_out_6997_100' class='stacks_out'><div id='stacks_in_6997_100' class='stacks_in stack_stack in item-federated-node item-general'><div id='stacks_out_6997_101' class='stacks_out'>
1533<div id='stacks_in_6997_101' class='stacks_in html_stack in item-title'><a href="#" class="item-federated-node-on">Federated node</a></div></div><div id='stacks_out_6997_104' class='stacks_out'><div id='stacks_in_6997_104' class='stacks_in text_stack in item-body'><p>A server containing a clinical database which can be connected to from a central computer using web services (HTTPS)</p></div></div></div></div><div id='stacks_out_6997_70' class='stacks_out'><div id='stacks_in_6997_70' class='stacks_in stack_stack in item-gastric-bypass item-general'><div id='stacks_out_6997_71' class='stacks_out'><div id='stacks_in_6997_71' class='stacks_in html_stack in item-title'><a href="#" class="item-gastric-bypass-on">Gastric bypass</a></div></div><div id='stacks_out_6997_74' class='stacks_out'><div id='stacks_in_6997_74' class='stacks_in text_stack in item-body'><p>A surgical bypass operation that typically involves reducing the size of the stomach and reconnecting the smaller stomach to bypass the first portion of the small intestine so as to restrict food intake and reduce caloric absorption in cases of severe obesity (source: <a href="https://merriam-webster.com/" target="_blank">https://merriam-webster.com/</a>).</p></div></div></div></div><div id='stacks_out_6997_64' class='stacks_out'><div id='stacks_in_6997_64' class='stacks_in stack_stack in item-insulin-target item-general'><div id='stacks_out_6997_65' class='stacks_out'><div id='stacks_in_6997_65' class='stacks_in html_stack in item-title'><a href="#" class="item-insulin-target-on">Insulin target tissues</a></div></div><div id='stacks_out_6997_68' class='stacks_out'><div id='stacks_in_6997_68' class='stacks_in text_stack in item-body'><p>Organs where insulin exerts its blood glucose lowering action. Liver: insulin decreases glucose production; muscles and adipose tissue: insulin stimulates glucose uptake.</p></div></div></div></div><div id='stacks_out_6997_106' class='stacks_out'><div id='stacks_in_6997_106' class='stacks_in stack_stack in item-multi-omics item-general'><div id='stacks_out_6997_107' class='stacks_out'><div id='stacks_in_6997_107' class='stacks_in html_stack in item-title'><a href="#" class="item-multi-omics-on">Multi-omics</a></div></div><div id='stacks_out_6997_110' class='stacks_out'><div id='stacks_in_6997_110' class='stacks_in text_stack in item-body'><p>Multi-omics refer to biological information in the form of any molecules in our bodies which are part of our everyday functioning and can change during diseases.</p><p><b>Genomics: </b>study of the full genetics components of an organism (the genome) which includes the entire DNA sequence. It also considers the inter-relationships between the genes and their interaction with environmental factors.</p><p><br /><b>Transcriptomics: </b>transcriptomics is used to identify the qualitative and quantitative RNA levels in the whole genome. It can tell us which transcripts are present together with the levels of their expression. Almost 80% of the genome is transcribed to RNA.</p><p><br /><b>Proteomics: </b>study of the structure, function and physiological role of the entire proteins in a cell or tissue of an organism.</p><p><br /><b>Metabolomics:</b>study of the metabolites present in a cell or tissue/fluids of an organism. This includes small molecules, carbohydrates, peptides, lipids, nucleosides and metabolism products.</p><br /></div></div></div></div><div id='stacks_out_6997_137' class='stacks_out'><div id='stacks_in_6997_137' class='stacks_in stack_stack in item-ontology item-general'><div id='stacks_out_6997_138' class='stacks_out'><div id='stacks_in_6997_138' class='stacks_in html_stack in item-title'><a href="#" class="item-ontology-on">Ontology</a></div></div><div id='stacks_out_6997_141' class='stacks_out'><div id='stacks_in_6997_141' class='stacks_in text_stack in item-body'><p>A set of concepts and categories in a subject area or domain that shows their properties and the relations between them.</p></div></div></div></div><div id='stacks_out_6997_155' class='stacks_out'><div id='stacks_in_6997_155' class='stacks_in stack_stack in item-phenotypic-trait item-general'><div id='stacks_out_6997_156' class='stacks_out'>
1533<div id='stacks_in_6997_156' class='stacks_in html_stack in item-title'><a href="#" class="item-phenotypic-trait-on">Phenotypic trait</a></div></div><div id='stacks_out_6997_159' class='stacks_out'><div id='stacks_in_6997_159' class='stacks_in text_stack in item-body'><p>A phenotypic trait is an obvious, observable, and measurable trait; it is the expression of genes in an observable way. An example of a phenotypic trait is a specific hair color. Underlying genes, which make up the genotype, determine the hair color, but the hair color observed is the phenotype. The phenotype is dependent on the genetic make-up of the organism, and also influenced by the environmental conditions (source: <a href="https://en.wikipedia.org/wiki/Phenotypic_trait" target="_blank">https://en.wikipedia.org/wiki/Phenotypic_trait</a>)</p></div></div></div></div><div id='stacks_out_6997_149' class='stacks_out'><div id='stacks_in_6997_149' class='stacks_in stack_stack in item-PNLIPRP1 item-general'><div id='stacks_out_6997_150' class='stacks_out'><div id='stacks_in_6997_150' class='stacks_in html_stack in item-title'><a href="#" class="item-PNLIPRP1-on">PNLIPRP1</a></div></div><div id='stacks_out_6997_153' class='stacks_out'><div id='stacks_in_6997_153' class='stacks_in text_stack in item-body'><p>PNLIPRP1: this gene encodes for the protein called "pancreatic lipase-related protein 1" which may function as inhibitor of dietary triglyceride digestion (source: <a href="https://www.uniprot.org/uniprot/P54315" target="_blank">https://www.uniprot.org/uniprot/P54315</a>)</p></div></div></div></div><div id='stacks_out_6997_94' class='stacks_out'><div id='stacks_in_6997_94' class='stacks_in stack_stack in item-precision-medicine item-general'><div id='stacks_out_6997_95' class='stacks_out'><div id='stacks_in_6997_95' class='stacks_in html_stack in item-title'><a href="#" class="item-precision-medicine-on">Precision medicine</a></div></div><div id='stacks_out_6997_98' class='stacks_out'><div id='stacks_in_6997_98' class='stacks_in text_stack in item-body'><p>Precision medicine refers to the tailoring of medical treatment to the individual characteristics of each patient, [&hellip;] the ability to classify individuals into subpopulations that differ in their susceptibility to a particular disease, in the biology or prognosis of those diseases they may develop, or in their response to a specific treatment (definition from the US National Research Council, <a href=" https://en.wikipedia.org/wiki/Precision_medicine" target="_blank">https://en.wikipedia.org/wiki/Precision_medicine</a>).</p></div></div></div></div><div id='stacks_out_6997_52' class='stacks_out'><div id='stacks_in_6997_52' class='stacks_in stack_stack in item-impaired-glucose item-general'><div id='stacks_out_6997_53' class='stacks_out'><div id='stacks_in_6997_53' class='stacks_in html_stack in item-title'><a href="#" class="item-impaired-glucose-on">Prediabetes / Impaired glucose tolerance</a></div></div><div id='stacks_out_6997_56' class='stacks_out'><div id='stacks_in_6997_56' class='stacks_in text_stack in item-body'><p>When fasting blood glucose is raised beyond normal levels, but is not high enough to warrant a diabetes diagnosis (source:<a href="https://diabetes.co.uk/" target="_blank"> https://diabetes.co.uk/</a>)</p></div></div></div></div><div id='stacks_out_6997_82' class='stacks_out'><div id='stacks_in_6997_82' class='stacks_in stack_stack in item-qalys item-general'><div id='stacks_out_6997_83' class='stacks_out'><div id='stacks_in_6997_83' class='stacks_in html_stack in item-title'><a href="#" class="item-qalys-on">QALYs</a></div></div><div id='stacks_out_6997_86' class='stacks_out'><div id='stacks_in_6997_86' class='stacks_in text_stack in item-body'><p>Health benefits are often expressed as quality-adjusted life years (QALYs). QALYs combine longevity and quality of life in a single metric and allow comparisons across different treatments and diseases. As a result, the impact on QALYs are required by several European agencies to make decisions about whether to adopt and reimburse medicines at a national level. </p></div></div></div></div><div id='stacks_out_6997_131' class='stacks_out'><div id='stacks_in_6997_131' class='stacks_in stack_stack in item-r item-general'><div id='stacks_out_6997_132' class='stacks_out'>
1533<div id='stacks_in_6997_132' class='stacks_in html_stack in item-title'><a href="#" class="item-r-on">R</a></div></div><div id='stacks_out_6997_135' class='stacks_out'><div id='stacks_in_6997_135' class='stacks_in text_stack in item-body'><p>A programming language and free software environment for statistical computing and graphics supported by the R Foundation for Statistical Computing. The R language is widely used among statisticians and data miners for developing statistical software and data analysis (source: <a href="https://en.wikipedia.org/wiki/R_(programming_language)" target="_blank">https://en.wikipedia.org/wiki/R_(programming_language)</a>). </p></div></div></div></div><div id='stacks_out_6997_88' class='stacks_out'><div id='stacks_in_6997_88' class='stacks_in stack_stack in item-r-studio item-general'><div id='stacks_out_6997_89' class='stacks_out'><div id='stacks_in_6997_89' class='stacks_in html_stack in item-title'><a href="#" class="item-r-studio-on">RStudio Desktop</a></div></div><div id='stacks_out_6997_92' class='stacks_out'><div id='stacks_in_6997_92' class='stacks_in text_stack in item-body'><p>An integrated development environment for R that runs on Windows, Mac or Linux operating systems.</p></div></div></div></div><div id='stacks_out_6997_112' class='stacks_out'><div id='stacks_in_6997_112' class='stacks_in stack_stack in item-sensitivity item-general'><div id='stacks_out_6997_113' class='stacks_out'><div id='stacks_in_6997_113' class='stacks_in html_stack in item-title'><a href="#" class="item-sensitivity-on">Sensitivity</a></div></div><div id='stacks_out_6997_116' class='stacks_out'><div id='stacks_in_6997_116' class='stacks_in text_stack in item-body'><p>Sensitivity is the proportion of true-positives which actually test positive, and how well a test is able to detect positive individuals in a population (source: <a href="https://www.fws.gov/aah/PDF/SandS.pdf" target="_blank">https://www.fws.gov/aah/PDF/SandS.pdf</a>).</p></div></div></div></div><div id='stacks_out_6997_118' class='stacks_out'><div id='stacks_in_6997_118' class='stacks_in stack_stack in item-specificity item-general'><div id='stacks_out_6997_119' class='stacks_out'><div id='stacks_in_6997_119' class='stacks_in html_stack in item-title'><a href="#" class="item-specificity-on">Specificity</a></div></div><div id='stacks_out_6997_122' class='stacks_out'><div id='stacks_in_6997_122' class='stacks_in text_stack in item-body'><p>Specificity is the proportion of true-negatives which actually test negative, and reflects how well an assay performs in a group of disease negative individuals (source: <a href="https://www.fws.gov/aah/PDF/SandS.pdf" target="_blank">https://www.fws.gov/aah/PDF/SandS.pdf</a>).</p></div></div></div></div></div>
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1542</div></div><div id='stacks_out_7103' class='stacks_out'><div id='stacks_in_7103' class='stacks_in com_joeworkman_stacks_expose_stack'><div class="expose_launcher expose_video-p4"> <div class='slice empty out'><div class='slice empty in'></div></div>  </div> <div id="expose_video-p4" class="expose_lightbox"> <a class="close"></a> <div id='stacks_out_7121' class='stacks_out'><div id='stacks_in_7121' class='stacks_in html_stack'><div style="padding:56.25% 0 0 0;position:relative;"><iframe src="https://player.vimeo.com/video/610736073?h=a93e945542&amp;badge=0&amp;autopause=0&amp;player_id=0&amp;app_id=58479" frameborder="0" allow="autoplay; fullscreen; picture-in-picture" allowfullscreen style="position:absolute;top:0;left:0;width:100%;height:100%;" title="(4/9) RHAPSODY Final Symposium &amp;mdash; What does the Innovative Medicines Initiative do to help patients with diabetes? Claire Varin"></iframe></div>
1542<script src="https://player.vimeo.com/api/player.js"></script>
1542</div></div>  </div>  
1543</div></div><div id='stacks_out_7104' class='stacks_out'><div id='stacks_in_7104' class='stacks_in com_joeworkman_stacks_expose_stack'><div class="expose_launcher expose_video-p5"> <div class='slice empty out'><div class='slice empty in'></div></div>  </div> <div id="expose_video-p5" class="expose_lightbox"> <a class="close"></a> <div id='stacks_out_7125' class='stacks_out'><div id='stacks_in_7125' class='stacks_in html_stack'><div style="padding:56.25% 0 0 0;position:relative;"><iframe src="https://player.vimeo.com/video/610737189?h=60fb942df4&amp;badge=0&amp;autopause=0&amp;player_id=0&amp;app_id=58479" frameborder="0" allow="autoplay; fullscreen; picture-in-picture" allowfullscreen style="position:absolute;top:0;left:0;width:100%;height:100%;" title="(5/9) RHAPSODY Final Symposium &amp;mdash; Diabetes care: a clinician`s point of view, Andreas Festa"></iframe></div>
1543<script src="https://player.vimeo.com/api/player.js"></script>
1543</div></div>  </div>  
1544</div></div><div id='stacks_out_7105' class='stacks_out'><div id='stacks_in_7105' class='stacks_in com_joeworkman_stacks_expose_stack'><div class="expose_launcher expose_video-p6"> <div class='slice empty out'><div class='slice empty in'></div></div>  </div> <div id="expose_video-p6" class="expose_lightbox"> <a class="close"></a> <div id='stacks_out_7129' class='stacks_out'><div id='stacks_in_7129' class='stacks_in html_stack'><div style="padding:56.25% 0 0 0;position:relative;"><iframe src="https://player.vimeo.com/video/610738258?h=2961871d3a&amp;badge=0&amp;autopause=0&amp;player_id=0&amp;app_id=58479" frameborder="0" allow="autoplay; fullscreen; picture-in-picture" allowfullscreen style="position:absolute;top:0;left:0;width:100%;height:100%;" title="(6/9) RHAPSODY Final Symposium &amp;mdash; Diabetes care: a clinician`s point of view, Andreas Festa"></iframe></div>
1544<script src="https://player.vimeo.com/api/player.js"></script>
1544</div></div>  </div>  
1545</div></div><div id='stacks_out_7106' class='stacks_out'><div id='stacks_in_7106' class='stacks_in com_joeworkman_stacks_expose_stack'><div class="expose_launcher expose_video-p7"> <div class='slice empty out'><div class='slice empty in'></div></div>  </div> <div id="expose_video-p7" class="expose_lightbox"> <a class="close"></a> <div id='stacks_out_7133' class='stacks_out'><div id='stacks_in_7133' class='stacks_in html_stack'><div style="padding:56.25% 0 0 0;position:relative;"><iframe src="https://player.vimeo.com/video/610739919?h=e889760d00&amp;badge=0&amp;autopause=0&amp;player_id=0&amp;app_id=58479" frameborder="0" allow="autoplay; fullscreen; picture-in-picture" allowfullscreen style="position:absolute;top:0;left:0;width:100%;height:100%;" title="(7/9) RHAPSODY Final Symposium &amp;mdash; A new diabetes patient sub-classification: its application in RHAPSODY, Roderick Slieker"></iframe></div>
1545<script src="https://player.vimeo.com/api/player.js"></script>
1545</div></div>  </div>  
1546</div></div><div id='stacks_out_7107' class='stacks_out'><div id='stacks_in_7107' class='stacks_in com_joeworkman_stacks_expose_stack'><div class="expose_launcher expose_video-p8"> <div class='slice empty out'><div class='slice empty in'></div></div>  </div> <div id="expose_video-p8" class="expose_lightbox"> <a class="close"></a> <div id='stacks_out_7137' class='stacks_out'><div id='stacks_in_7137' class='stacks_in html_stack'><div style="padding:56.25% 0 0 0;position:relative;"><iframe src="https://player.vimeo.com/video/610742715?h=5e1ec29cc4&amp;badge=0&amp;autopause=0&amp;player_id=0&amp;app_id=58479" frameborder="0" allow="autoplay; fullscreen; picture-in-picture" allowfullscreen style="position:absolute;top:0;left:0;width:100%;height:100%;" title="(8/9) RHAPSODY Final Symposium &amp;mdash; Diabetes care: a clinician`s point of view, Andreas Festa"></iframe></div>
1546<script src="https://player.vimeo.com/api/player.js"></script>
1546</div></div>  </div>  
1547</div></div><div id='stacks_out_7108' class='stacks_out'><div id='stacks_in_7108' class='stacks_in com_joeworkman_stacks_expose_stack'><div class="expose_launcher expose_video-p9"> <div class='slice empty out'><div class='slice empty in'></div></div>  </div> <div id="expose_video-p9" class="expose_lightbox"> <a class="close"></a> <div id='stacks_out_7141' class='stacks_out'><div id='stacks_in_7141' class='stacks_in html_stack'><div style="padding:56.25% 0 0 0;position:relative;"><iframe src="https://player.vimeo.com/video/610743677?h=a2884aa4a5&amp;badge=0&amp;autopause=0&amp;player_id=0&amp;app_id=58479" frameborder="0" allow="autoplay; fullscreen; picture-in-picture" allowfullscreen style="position:absolute;top:0;left:0;width:100%;height:100%;" title="(9/9) RHAPSODY Final Symposium &amp;mdash; Wrap-up and conclusions, Claire Varin &amp;amp; Bernard Thorens"></iframe></div>
1547<script src="https://player.vimeo.com/api/player.js"></script>
1547</div></div>  </div>  
1548</div></div><div id='stacks_out_6845' class='stacks_out'><div id='stacks_in_6845' class='stacks_in '><div id='stacks_out_6845_218' class='stacks_out'><div id='stacks_in_6845_218' class='stacks_in com_yourhead_stacks_two_columns_stack'><div class='s3_row'>
1549	<div class='s3_column s3_column_left'><div id='stacks_out_6845_58' class='stacks_out'><div id='stacks_in_6845_58' class='stacks_in com_elstacko_stack_exposer_pro_stack'>
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1557<div id='stacks_out_6845_224' class='stacks_out'><div id='stacks_in_6845_224' class='stacks_in com_yourhead_stacks_two_columns_stack'><div class='s3_row'>
1558	<div class='s3_column s3_column_left'><div id='stacks_out_6845_2' class='stacks_out'><div id='stacks_in_6845_2' class='stacks_in com_yourhead_stacks_two_columns_stack'><div class='s3_row'>
1559	<div class='s3_column s3_column_left'><div   class="boxec" style=""> <div id='stacks_out_6845_46' class='stacks_out'><div id='stacks_in_6845_46' class='stacks_in image_stack'>
1560<div class='centered_image' >
1561    <img class='imageStyle' src='files/stacks-image-38c02b0.png' alt='Stacks Image 47' />
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1568<div class='centered_image' >
1569    <img class='imageStyle' src='files/stacks-image-c805eb8.png' alt='Stacks Image 398' />
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1574<div   class="boxefpia" style=""> <div id='stacks_out_6845_50' class='stacks_out'><div id='stacks_in_6845_50' class='stacks_in image_stack'>
1575<div class='centered_image' >
1576    <img class='imageStyle' src='files/stacks-image-0ac8b36.png' alt='Stacks Image 51' />
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1579</div></div></div>
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1581<div   class="boxseri" style=""> <div id='stacks_out_6845_348' class='stacks_out'><div id='stacks_in_6845_348' class='stacks_in image_stack'>
1582<div class='centered_image' >
1583    <img class='imageStyle' src='files/stacks-image-1364b57.png' alt='Stacks Image 349' />
1584</div>
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1586</div></div></div>
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1588</div>
1589</div></div></div></div>
1590	<div class='s3_column s3_column_right'><div   class="imgtext_1" style=""> <div id='stacks_out_6845_19' class='stacks_out'><div id='stacks_in_6845_19' class='stacks_in text_stack'>This project has received funding from the Innovative Medicines Initiative 2 Joint Undertaking (<a href="https://www.imi.europa.eu" target="_blank">www.imi.europa.eu</a>) under grant agreement No 115881. This Joint Undertaking has received support from the European Union&rsquo;s Horizon 2020 research and innovation programme and EFPIA. <br /><br />This work has been supported by the Swiss State Secretariat for Education&sbquo; Research and Innovation (SERI) under&nbsp;contract&nbsp;number 16.0097-2.<br /><br />The opinions expressed and arguments employed herein do not necessarily reflect the official views of these funding bodies.</div></div></div>
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1592</div>
1593</div></div></div>
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1596</div>
1597<div style="clear: both;"></div></div></div><div id='stacks_out_6845_56' class='stacks_out'><div id='stacks_in_6845_56' class='stacks_in com_elstacko_stack_exposer_pro_stack'>
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1602<div class="shell" >
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1604<div id="fot1" style="display:none;">
1605<div   class="imgtext_2" style=""> <div id='stacks_out_6845_275' class='stacks_out'><div id='stacks_in_6845_275' class='stacks_in com_yourhead_stack_float_stack'><div id='stacks_in_6845_275_float'><div id='stacks_out_6845_236' class='stacks_out'><div id='stacks_in_6845_236' class='stacks_in image_stack'>
1606<div class='centered_image' >
1607    <img class='imageStyle' src='files/stacks-image-8b2cdf3.png' alt='Stacks Image 237' />
1608</div>
1609
1610</div></div></div><a href="#" onclick="$('#fot_base').slideToggle('slow');$('#fot1,#fot2,#fot3,#fot4,#fot5').hide('slow'); return false;"><i class="fa fa-times fa-2x fa-fw pull-right" aria-hidden="true"></i></a>Horizon 2020 is the biggest EU Research and Innovation programme ever with nearly &euro;80 billion of funding available over 7 years (2014 to 2020). In addition to the private investment that this money will attract. It promises more breakthroughs, discoveries and world-firsts by taking great ideas from the lab to the market.<br />Rhapsody is funded under the "Health" priority, which is an investment in our health and, on a larger scale, an investment in a healthy workforce, a healthy economy and lower public health bills.</div></div><div id='stacks_out_6845_280' class='stacks_out'><div id='stacks_in_6845_280' class='stacks_in text_stack'><a href="https://ec.europa.eu/programmes/horizon2020/en/area/health" rel="external"><i class="fa fa-external-link-square fa-lg fa-fw" aria-hidden="true"></i> Learn more</a></div></div><div id='stacks_out_6845_282' class='stacks_out'><div id='stacks_in_6845_282' class='stacks_in text_stack'><a href="#" onclick="$('#fot_base').slideToggle('slow');$('#fot1,#fot2,#fot3,#fot4,#fot5').hide('slow'); return false;"><i class="fa fa-times fa-lg fa-fw" aria-hidden="true"></i> Close this window </a></div></div></div>
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1614</div>
1615</div>
1616<div style="clear: both;"></div></div></div><div id='stacks_out_6845_54' class='stacks_out'><div id='stacks_in_6845_54' class='stacks_in com_elstacko_stack_exposer_pro_stack'>
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1621<div class="shell" >
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1623<div id="fot2" style="display:none;">
1624<div   class="imgtext_2" style=""> <div id='stacks_out_6845_264' class='stacks_out'><div id='stacks_in_6845_264' class='stacks_in com_yourhead_stack_float_stack'><div id='stacks_in_6845_264_float'><div id='stacks_out_6845_331' class='stacks_out'><div id='stacks_in_6845_331' class='stacks_in image_stack'>
1625<div class='centered_image' >
1626    <img class='imageStyle' src='files/stacks-image-7fe0d52.png' alt='Stacks Image 332' />
1627</div>
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1629</div></div></div><a href="#" onclick="$('#fot_base').slideToggle('slow');$('#fot1,#fot2,#fot3,#fot4,#fot5').hide('slow'); return false;"><i class="fa fa-times fa-2x fa-fw pull-right" aria-hidden="true"></i></a>
1629The Innovative Medicines Initiative (IMI) is Europe's largest public-private initiative aiming to speed up the development of better and safer medicines for patients.<br />IMI supports collaborative research projects and builds networks of industrial and academic experts in order to boost pharmaceutical innovation in Europe.<br />IMI is a joint undertaking between the European Union and the pharmaceutical industry association EFPIA.</div></div><div id='stacks_out_6845_269' class='stacks_out'><div id='stacks_in_6845_269' class='stacks_in text_stack'><a href="https://www.imi.europa.eu/" rel="external"><i class="fa fa-external-link-square fa-lg fa-fw" aria-hidden="true"></i> Learn more</a></div></div><div id='stacks_out_6845_271' class='stacks_out'><div id='stacks_in_6845_271' class='stacks_in text_stack'><a href="#" onclick="$('#fot_base').slideToggle('slow');$('#fot1,#fot2,#fot3,#fot4,#fot5').hide('slow'); return false;"><i class="fa fa-times fa-lg fa-fw" aria-hidden="true"></i> Close this window </a></div></div></div>
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1633</div>
1634</div>
1635<div style="clear: both;"></div></div></div><div id='stacks_out_6845_52' class='stacks_out'><div id='stacks_in_6845_52' class='stacks_in com_elstacko_stack_exposer_pro_stack'>
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1640<div class="shell" >
1641
1642<div id="fot3" style="display:none;">
1643<div   class="imgtext_2" style=""> <div id='stacks_out_6845_394' class='stacks_out'><div id='stacks_in_6845_394' class='stacks_in com_yourhead_stacks_two_columns_stack'><div class='s3_row'>
1644	<div class='s3_column s3_column_left'><div class='slice empty out'><div class='slice empty in'></div></div></div>
1645	<div class='s3_column s3_column_right'><div class='slice empty out'><div class='slice empty in'></div></div></div>
1646</div></div></div><div id='stacks_out_6845_253' class='stacks_out'><div id='stacks_in_6845_253' class='stacks_in com_yourhead_stack_float_stack'><div id='stacks_in_6845_253_float'><div id='stacks_out_6845_255' class='stacks_out'><div id='stacks_in_6845_255' class='stacks_in image_stack'>
1647<div class='centered_image' >
1648    <img class='imageStyle' src='files/stacks-image-a15ff7d.png' alt='Stacks Image 256' />
1649</div>
1650
1651</div></div></div><a href="#" onclick="$('#fot_base').slideToggle('slow');$('#fot1,#fot2,#fot3,#fot4,#fot5').hide('slow'); return false;"><i class="fa fa-times fa-2x fa-fw pull-right" aria-hidden="true"></i></a>EFPIA brings together 33 European national pharmaceutical industry associations as well as 42 leading companies undertaking research, development and the manufacture in Europe of medicinal products for human use. <br />The EFPIA Manager Research Partnerships plays a critical role in enabling participation of EFPIA members in collaborative research and development in the framework of private-private and public-private partnerships, such as but not limited to the Innovative Medicines Initiative or EU framework programmes. </div></div><div id='stacks_out_6845_259' class='stacks_out'><div id='stacks_in_6845_259' class='stacks_in text_stack'><a href="http://www.efpia.eu/" rel="external"><i class="fa fa-external-link-square fa-lg fa-fw" aria-hidden="true"></i> Learn more</a></div></div><div id='stacks_out_6845_261' class='stacks_out'><div id='stacks_in_6845_261' class='stacks_in text_stack'><a href="#" onclick="$('#fot_base').slideToggle('slow');$('#fot1,#fot2,#fot3,#fot4,#fot5').hide('slow'); return false;"><i class="fa fa-times fa-lg fa-fw" aria-hidden="true"></i> Close this window </a></div></div></div>
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1655</div>
1656</div>
1657<div style="clear: both;"></div></div></div><div id='stacks_out_6845_381' class='stacks_out'><div id='stacks_in_6845_381' class='stacks_in com_elstacko_stack_exposer_pro_stack'>
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1661
1662<div class="shell" >
1663
1664<div id="fot5" style="display:none;">
1665<div   class="imgtext_2" style=""> <div id='stacks_out_6845_383' class='stacks_out'><div id='stacks_in_6845_383' class='stacks_in com_yourhead_stack_float_stack'><div id='stacks_in_6845_383_float'><div id='stacks_out_6845_385' class='stacks_out'><div id='stacks_in_6845_385' class='stacks_in image_stack'>
1666<div class='centered_image' >
1667    <img class='imageStyle' src='files/stacks-image-b904092.png' alt='Stacks Image 386' />
1668</div>
1669
1670</div></div></div><a href="#" onclick="$('#fot_base').slideToggle('slow');$('#fot1,#fot2,#fot3,#fot4,#fot5').hide('slow'); return false;"><i class="fa fa-times fa-2x fa-fw pull-right" aria-hidden="true"></i></a>The State Secretariat for Education, Research and Innovation SERI within the Federal Department of Economic Affairs, Education and Research EAER is the Swiss federal government's specialised agency for national and international matters concerning education, research and innovation policy.</div></div><div id='stacks_out_6845_388' class='stacks_out'><div id='stacks_in_6845_388' class='stacks_in text_stack'><a href="https://www.sbfi.admin.ch/sbfi/en/home.html" rel="external"><i class="fa fa-external-link-square fa-lg fa-fw" aria-hidden="true"></i> Learn more</a></div></div><div id='stacks_out_6845_390' class='stacks_out'><div id='stacks_in_6845_390' class='stacks_in text_stack'><a href="#" onclick="$('#fot_base').slideToggle('slow');$('#fot1,#fot2,#fot3,#fot4,#fot5').hide('slow'); return false;"><i class="fa fa-times fa-lg fa-fw" aria-hidden="true"></i> Close this window </a></div></div></div>
1671
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1674</div>
1675</div>
1676<div style="clear: both;"></div></div></div><div id='stacks_out_6845_302' class='stacks_out'><div id='stacks_in_6845_302' class='stacks_in com_elstacko_stack_exposer_pro_stack'>
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1681<div class="shell" >
1682
1683<div id="fot4" style="display:none;">
1684<div   class="imgtext_2" style=""> <div id='stacks_out_6845_321' class='stacks_out'><div id='stacks_in_6845_321' class='stacks_in text_stack'><a href="#" onclick="$('#fot_base').slideToggle('slow');$('#fot1,#fot2,#fot3,#fot4,#fot5').hide('slow'); return false;"><i class="fa fa-times fa-2x fa-fw pull-right" aria-hidden="true"></i></a>Please fill the contact form below to send a message to RHAPSODY. You can address our project coordinator as well as our project manager.</div></div><div id='stacks_out_6845_285' class='stacks_out'><div id='stacks_in_6845_285' class='stacks_in com_yabdab_stacks_formsnapBase_stack'>
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1694<form action="files/stacks_in_6845_285_formsnap.php" method="post" class="no-steps no-fouc" enctype="multipart/form-data" data-parsley-validate="" role="form" id="yd-form-stacks_in_6845_285" autocomplete="off" >
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1696<input type="hidden" name="yd_csrf_token" value="3baf31dab77d9f0ce845712f1ad100ec">
1697<input type="hidden" name="yd_logo" id="yd-logo-stacks_in_6845_285" value="">
1698<input type="hidden" name="yd_url" value="https://imi-rhapsody.eu/index.php">
1699<input type="hidden" name="email_template" value="This message has been sent by &lt;b&gt;#name#&lt;/b&gt; via the Rhapsody Website contact form.&lt;br /&gt;&lt;br /&gt;This is the request:&lt;br /&gt;&lt;b&gt;#message#&lt;/b&gt;"><input type="hidden" name="receipt_template" value="">
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1714<input autocomplete="off" type="text" class="yd-input " data-parsley-required data-parsley-required-message="This field is Required." name="form[name]" id="name" placeholder="Your name..." value="" tabindex="1" />
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1722<label for="mail" title="Your e-mail"><i class=" yd-icon"></i> Your e-mail <span class="yd-required"><i class="fa fa-asterisk"></i></label>
1723
1724<input autocomplete="off" type="email" data-parsley-type="email" data-parsley-type-message="Please enter a valid email address." class="yd-input yd-email " data-parsley-required data-parsley-required-message="This field is Required." name="form[mail]" id="mail" placeholder="Please enter a valid address..." value="" tabindex="2" />
1725<input type="hidden" name="fs_items[mail]" value="{&quot;id&quot;:&quot;stacks_in_6845_290&quot;,&quot;l&quot;:&quot;Your e-mail&quot;,&quot;m&quot;:&quot;False&quot;,&quot;g&quot;:&quot;False&quot;,&quot;c&quot;:&quot;&quot;,&quot;n&quot;:&quot;mail&quot;,&quot;t&quot;:&quot;
1725string&quot;,&quot;fsa&quot;:&quot;&quot;}" />
1726</div></div>
1727
1728<div id='stacks_out_6845_327' class='stacks_out'><div id='stacks_in_6845_327' class='stacks_in com_yourhead_stacks_two_columns_stack'><div class='s3_row'>
1729	<div class='s3_column s3_column_left'>
1730
1731<!-- FormSnap v.3.0.8 Submit Button -->
1732
1733<div class="control-group yd-btn-group incase" id="fs-item-stacks_in_6845_292">
1734  <div><p>
1735<button type="submit" id="fs-item-stacks_in_6845_292" class="yd-btn yd-primary btn-default   " tabindex="4">Send</button>
1736</p></div>
1737</div>
1738
1739
1740
1741
1742</div>
1743	<div class='s3_column s3_column_right'>
1744
1745
1746<!-- FormSnap  v.3.0.8 Reset Button -->
1747
1748<div class="control-group yd-btn-group incase" id="fs-item-stacks_in_6845_330">
1749  <div><p>
1750<button type="reset" class="yd-btn btn-default   formsnap-reset " tabindex="5">Reset</button>
1751</p></div>
1752</div>
1753
1754
1755
1756</div>
1757</div></div></div></div>
1758	<div class='s3_column s3_column_right'>
1759
1760<!-- FormSnap v.3.0.8 Textarea -->
1761<div class="control-group yd-textarea incase" id="fs-item-stacks_in_6845_298"><div>
1762
1763
1764<label for="message" title="Your message"><i class=" yd-icon"></i> Your message 
1765 <span class="yd-required"><i class="fa fa-asterisk"></i></span>
1766
1767</label>
1768
1769
1770<textarea autocomplete="off" class=""
1771style="height:173px; resize:none;"
1772 required data-parsley-required data-parsley-required-message="This field is Required."
1773
1774
1775name="form[message]" 
1776id="message" 
1777placeholder="Enter text here..." 
1778tabindex="3"></textarea>
1779</div>
1780
1781</div>
1782
1783<input type="hidden" name="fs_items[message]" value="{&quot;id&quot;:&quot;stacks_in_6845_298&quot;,&quot;l&quot;:&quot;Your message&quot;,&quot;m&quot;:&quot;False&quot;,&quot;g&quot;:&quot;False&quot;,&quot;c&quot;:&quot;&quot;,&quot;n&quot;:&quot;message&quot;,&quot;t&quot;:&quot;string&quot;,&quot;fsa&quot;:&quot;&quot;}" />
1784
1785
1786
1787
1788<!-- FormSnap v.3.0.8 Input Field -->
1789
1790<input autocomplete="off" type="hidden" class="yd-input yd-hidden " name="form[subject]" id="subject" placeholder="Please fill out..." value="You have a new message from the Rhapsody website!" tabindex="5" />
1791<input type="hidden" name="fs_items[subject]" value="{&quot;id&quot;:&quot;stacks_in_6845_299&quot;,&quot;l&quot;:&quot;Input Label&quot;,&quot;m&quot;:&quot;False&quot;,&quot;g&quot;:&quot;False&quot;,&quot;c&quot;:&quot;&quot;,&quot;n&quot;:&quot;subject&quot;,&quot;t&quot;:&quot;string&quot;,&quot;fsa&quot;:&quot;&quot;}" />
1792
1793
1794</div>
1795</div></div></div> 
1796 <div class='slice empty out'><div class='slice empty in'></div></div>
1797 
1798</div><!-- fs-grid-container -->
1799</section><!-- yd-step -->
1800
1801<div class="form-navigation bottom" style="display:none;">
1802  <div class="fs-col fs-col-4">
1803    <button type="button" class="yd-btn previous pull-left"><i class="fa fa-chevron-left"></i> Previous</button>
1804  </div>
1805  <div class="fs-col fs-col-4">
1806    <div class="yd-step-dots">
1807      <ul>
1808      </ul>
1809    </div>
1810  </div>
1811  <div class="fs-col fs-col-4">
1812    <button type="button" class="yd-btn next pull-right">Next <i class="fa fa-chevron-right"></i></button>
1813    <button type="submit" class="yd-btn yd-primary pull-right"><span><i class="fa fa-paper-plane"></i></span> Submit</button>
1814  </div>
1815</div>
1816
1817<input type="hidden" name="ydfs_stacks_id" value="stacks_in_6845_285" />
1818<input type="text" name="rellikmaps" class="rellikmaps" value="" />
1819</form>
1820<div id="yd-form-results"></div>
1821
1822
1823
1824
1825
1826</div><!-- .yd-reset -->
1827<div id="stacks_in_6845_285-yd-modal" class="yd-modal yd-effect-1">
1828  <div class="yd-content">
1829    <div class="yd-modal-close" style="font-size:18px; position:absolute; top:10px; left:20px; cursor:pointer;"><i class="fa fa-times"></i></div>
1830    <h3>Processing...</h3>
1831    <div class="yd-body">
1832      <p class="msg"></p>
1833    </div>
1834  </div>
1835</div>
1836<div class="yd-overlay"></div>
1837
1838
1839
1840
1841
1842
1843
1844</div></div><div id='stacks_out_6845_311' class='stacks_out'><div id='stacks_in_6845_311' class='stacks_in text_stack'><a href="#" onclick="$('#fot_base').slideToggle('slow');$('#fot1,#fot2,#fot3,#fot4,#fot5').hide('slow'); return false;"><i class="fa fa-times fa-lg fa-fw" aria-hidden="true"></i> Close this window </a></div></div></div>
1845
1846
1847
1848</div>
1849</div>
1850<div style="clear: both;"></div></div></div></div>
1851	<div class='s3_column s3_column_right'><div id='stacks_out_6845_221' class='stacks_out'><div id='stacks_in_6845_221' class='stacks_in com_yourhead_stacks_two_columns_stack'><div class='s3_row'>
1852	<div class='s3_column s3_column_left'><div id='stacks_out_6845_66' class='stacks_out'><div id='stacks_in_6845_66' class='stacks_in stack_stack'><div   class="bottommenu" style=""> <div id='stacks_out_6845_316' class='stacks_out'><div id='stacks_in_6845_316' class='stacks_in com_joeworkman_stacks_link_stack'><a href="#h2020" onclick="$('#fot1').show('slow');$('#fot_base,#fot2,#fot3,#fot4,#fot5').hide('slow'); return false;"> <div id='stacks_out_6845_317' class='stacks_out'><div id='stacks_in_6845_317' class='stacks_in text_stack'><i class="fa fa-arrow-circle-o-right" aria-hidden="true"></i> About Horizon 2020</div></div> </a> 
1853</div></div></div>
1854
1855<div   class="bottommenu" style=""> <div id='stacks_out_6845_30' class='stacks_out'><div id='stacks_in_6845_30' class='stacks_in com_joeworkman_stacks_link_stack'><a href="#imi" onclick="$('#fot2').show('slow');$('#fot_base,#fot1,#fot3,#fot4,#fot5').hide('slow'); return false;"> <div id='stacks_out_6845_31' class='stacks_out'><div id='stacks_in_6845_31' class='stacks_in text_stack'><i class="fa fa-arrow-circle-o-right" aria-hidden="true"></i> About IMI</div></div> </a> 
1856</div></div></div>
1857
1858<div   class="bottommenu" style=""> <div id='stacks_out_6845_36' class='stacks_out'><div id='stacks_in_6845_36' class='stacks_in com_joeworkman_stacks_link_stack'><a href="#efpia" onclick="$('#fot3').show('slow');$('#fot_base,#fot2,#fot1,#fot4,#fot5').hide('slow'); return false;"> <div id='stacks_out_6845_37' class='stacks_out'><div id='stacks_in_6845_37' class='stacks_in text_stack'><i class="fa fa-arrow-circle-o-right" aria-hidden="true"></i> About EFPIA</div></div> </a> 
1859</div></div></div>
1860
1861<div   class="bottommenu" style=""> <div id='stacks_out_6845_340' class='stacks_out'><div id='stacks_in_6845_340' class='stacks_in com_joeworkman_stacks_link_stack'><a href="#efpia" onclick="$('#fot5').show('slow');$('#fot_base,#fot2,#fot1,#fot4,#fot3').hide('slow'); return false;"> <div id='stacks_out_6845_341' class='stacks_out'><div id='stacks_in_6845_341' class='stacks_in text_stack'><i class="fa fa-arrow-circle-o-right" aria-hidden="true"></i> About SERI</div></div> </a> 
1862</div></div></div>
1863
1864<div   class="bottommenu" style=""> <div id='stacks_out_6845_24' class='stacks_out'><div id='stacks_in_6845_24' class='stacks_in com_joeworkman_stacks_link_stack'><a href="#contact" onclick="$('#fot4').show('slow');$('#fot_base,#fot2,#fot3,#fot1,#fot5').hide('slow'); return false;"> <div id='stacks_out_6845_25' class='stacks_out'><div id='stacks_in_6845_25' class='stacks_in text_stack'><i class="fa fa-envelope" aria-hidden="true"></i> Contact Us</div></div> </a> 
1865</div></div></div>
1866
1867<div   class="bottommenu" style=""> <div id='stacks_out_6845_400' class='stacks_out'><div id='stacks_in_6845_400' class='stacks_in com_joeworkman_stacks_link_stack'><a href="../privacy-policy"> <div id='stacks_out_6845_401' class='stacks_out'><div id='stacks_in_6845_401' class='stacks_in text_stack'><i class="fa fa-eye" aria-hidden="true"></i> Privacy Policy</div></div> </a> 
1868</div></div></div>
1869
1870</div></div></div>
1871	<div class='s3_column s3_column_right'><div id='stacks_out_6845_42' class='stacks_out'><div id='stacks_in_6845_42' class='stacks_in image_stack'>
1872<div class='centered_image' >
1873    <a href="" onclick="$('#fot_base').slideToggle('slow');$('#fot1,#fot2,#fot3,#fot4').hide('slow'); return false;"><img class='imageStyle' src='files/stacks-image-a2b40c9.png' alt='Stacks Image 43' /></a>
1874</div>
1875
1876</div></div><div id='stacks_out_6845_410' class='stacks_out'><div id='stacks_in_6845_410' class='stacks_in html_stack'><div class="copyright_in">
1877		© 2019 RHAPSODY Project<br>Created by <a href="https://www.sciprom.ch" target="blank_">SCIPROM</a><br><span class="creative"><a rel="license" href="http://creativecommons.org/licenses/by-nc-nd/4.0/" target="_blank"><i class="fab fa-creative-commons "></i><i class="fab fa-creative-commons-by "></i><i class="fab fa-creative-commons-nc-eu "></i><i class="fab fa-creative-commons-nd "></i></a></span><br>
1878
1879	</div></div></div></div>
1880</div></div></div></div>
1881</div></div></div></div></div></div></div>
1882
1883		</div>
1884		
1885	</div>
1886
1887	
1887<script src="rw_common/assets/global.js"></script>
1887
1888</body>
1889
1890</html>

Line numbers count LF bytes from the start of the resource, as the search results do. Vendor segments are library code the classifier recognised; they are stored but not indexed. Bytes are shown as Latin1 characters, one per byte.