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84                    <h3 id="hatzakis--lab">Hatzakis Lab</h3>
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133                    <h3>Hatzakis Lab</h3>
134                    <h2>Single Molecule | Cell Biophysics</h2>
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146                <h2>Our Vision</h2>
147                <p>Our vision is to understand biology one molecule at a time. We strive to provide a dynamic and
148                    quantitative understanding in structural and cell biology and to utilize this information to control
149                    aberrant biological function. We approach this formidable challenge with an eclectic mix of
150                    quantitative single particle microscopy techniques and machine learning analysis.</p>
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158                <h2>Who we are</h2>
159                <p>The main objective of my group is to augment our understanding on the molecular mechanisms that
160                    underlie and control vital cellular functions. We approach this challenge by deciphering the dynamic
161                    interplay between the function and spatiotemporal localization of biomolecules (virus, dug
162                    nanocarrier, oligonucleotides or protein assemblies) and how this correlate to cellular and
163                    organismal response. We utilize an eclectic mix of single particle te
163chniques that promises to shed
164                    light on the interplays between the behaviour (dynamics, function and localisation) of biomolecules
165                    and high throughput single particle screening methodologies to decipher oligonucleotide interactions
166                    with membranes.
167                    <br>
168                    Recognizing that 4D imaging generates terabytes of data sets, that are hard to be quantitatively
169                    evaluated by current semi-manual analysis, we have developed toolboxes based on machine learning to
170                    rapidly and reliably, analyze the wealth of novel microscopy data we, and others, produce. Our
171                    all-inclusive softwares for windows and macs, offer accelerate by 5 orders of magnitude transition
172                    from raw data to quantitative analysis. These combined methodologies bridge 4D imaging with
173                    sophisticate image analysis required for delving into the era of 4D cell and tissue imaging.</p>
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216                <h3>Hatzakis Lab</h3>
217                <p>Thorvaldsensvej 40</p>
218                <p>Frederiksberg 1871</p>
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