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66="outside" aria-expanded="false">EVENTS</a><div class="dropdown-menu show" aria-labelledby="dropdown-392" data-bs-popper="none"><a class="text-primary dropdown-item display-4" href="events.html">Training retreats</a><a class="text-primary show dropdown-item display-4" href="hologen_symposium.html">Hologen Symposium</a><a class="text-primary dropdown-item display-4" href="https://www.hologen-network.eu/training/" target="_blank">Training materials</a></div> 67 </li> 68 <li class="nav-item"> 69 <a class="nav-link link text-primary display-4" href="contact.html"> 70 CONTACT</a> 71 </li></ul> 72 73 74 75 </div> 76 77 </div> 78 </nav> 79</section> 80 81<section data-bs-version="5.1" class="header3 factm5 cid-ulGl6reG8g" id="aheader3-12"> 82 83 84 85 86 87 88 <div class="container"> 89 <div class="content-container"> 90 <div class="item-left"> 91 <h1 class="mbr-section-title mbr-fonts-style mb-0 display-1"> 92 Concept</h1> 93 94 </div> 95 96 </div> 97 </div> 98</section> 99 100<section data-bs-version="5.1" class="article01 divem5 cid-ulD5i35J8X" id="article01-a"> 101 102 103 104 105 106 <div class="container-fluid"> 107 <div class="row"> 108 <div class="col-12 col-lg-6 card"> 109 <div class="image-wrapper"> 110 <img src="assets/images/mbr-1876x1407.jpg" alt="Mobirise"> 111 <img src="assets/images/mbr-1876x1251.jpg" alt="Mobirise"> 112 </div> 113 </div> 114 <div class="col-12 col-lg-6 card"> 115 <div class="title-wrapper"> 116 <h2 class="mbr-section-title mbr-fonts-style display-2"> 117 <strong>HOLOGENOMICS</strong></h2> 118 <p class="mbr-text mbr-fonts-style display-5"> 119 relies on the generation and analysis of host genomic and microbial metagenomic data to detect the interactions between them and identify the biological impact of such interactions on both hosts and associated microorganism communities. 120 </p> 121 122 </div> 123 </div> 124 </div> 125 </div> 126</section> 127 128<section data-bs-version="5.1" class="features03 merchm5 cid-ulGntcmVoY" id="features03-15"> 129 130 131 132 133 134 <div class="container"> 135 <div class="row"> 136 <div class="col-12"> 137 138 </div> 139 <div class="col-12"> 140 <div class="items-wrapper"> 141 <div class="item features-without-image item-mb"> 142 <div class="item-wrapper"> 143 <div class="card-box"> 144 <h4 class="item-title mbr-fonts-style display-5"> 145 Host-microbe interactions</h4> 146 <p class="item-text mbr-fonts-style display-7"> 147 The core of <strong>HoloGen</strong> revolves around the idea that a macroscopic organism, be it fungi, animal (including humans) or plant, can be viewed as an emergent property of interactions between that organism - i.e. host - and the microbes living on and inside it. Many biological processes in animals and their associated microorganisms are affected or modulated through such a symbiotic relationship. </p> 148 </div> 149 </div> 150 </div> 151 <div class="item features-without-image item-mb"> 152 <div class="item-wrapper"> 153 <div class="card-box"> 154 <h4 class="item-title mbr-fonts-style display-5"> 155 Analytical technologies<br></h4> 156 <p class="item-text mbr-fonts-style display-7"> 157 The recent development of high throughput biomolecular data generation platforms and <br>
157 the improvement of data processing infrastructures, it is now possible to screen virtually the entire biochemical landscape where hosts and microorganisms interact. This necessitates a truly multidisciplinary approach consisting of the analysis of genomes, transcriptomes, proteomes and metabolomes of both animals and their associated microorganisms.</p> 158 </div> 159 </div> 160 </div> 161 <div class="item features-without-image item-mb"> 162 <div class="item-wrapper"> 163 <div class="card-box"> 164 <h4 class="item-title mbr-fonts-style display-5"> 165 A one-health approach</h4> 166 <p class="item-text mbr-fonts-style display-7"><strong> 167 HoloGen</strong> targets significant, ground-breaking scientific advancement in our knowledge about functional interconnections between hosts and microbiomes through its use of cutting-edge omics-based measurements of molecular states coupled with novel computational approaches, to address scientific questions regarding human and animal health, agricultural production, microbial ecology, and more.</p> 168 </div> 169 </div> 170 </div> 171 </div> 172 </div> 173 </div> 174 </div> 175</section> 176 177<section data-bs-version="5.1" class="features02 divem5 cid-ulGl04L1cC" id="features02-11"> 178 179 180 181 182 183 <div class="container"> 184 <div class="row"> 185 <div class="col-12 col-lg-4"> 186 <div class="title-wrapper"> 187 <h2 class="mbr-section-title mbr-fonts-style display-5"> 188 <strong>Research Objectives</strong></h2> 189 </div> 190 </div> 191 <div class="col-12 col-lg-8"> 192 <div class="items"> 193 <div class="item features-without-image item-mb"> 194 <div class="item-wrapper"> 195 <div class="card-box"> 196 <div class="icon-wrapper"> 197 <span class="mbr-iconfont mobi-mbri-sites mobi-mbri"></span> 198 </div> 199 <h4 class="item-title mbr-fonts-style display-7"><strong>Develop novel computational approaches</strong></h4> 200 <p class="mbr-text mbr-fonts-style display-4">to model the biochemical, genetic, temporal and spatial levels of host-microbiota interactions in hologenomic research.<br></p> 201 </div> 202 </div> 203 </div> 204 <div class="item features-without-image item-mb"> 205 <div class="item-wrapper"> 206 <div class="card-box"> 207 <div class="icon-wrapper"> 208 <span class="mbr-iconfont mobi-mbri-update mobi-mbri"></span> 209 </div> 210 <h4 class="item-title mbr-fonts-style display-7"><strong>Understand fundamental principles of biochemical and ecological interplay</strong></h4> 211 <p class="mbr-text mbr-fonts-style display-4">between animal hosts and their associated microorganisms through applying a hologenomic perspective.<br></p> 212 </div> 213 </div> 214 </div> 215 <div class="item features-without-image item-mb"> 216 <div class="item-wrapper"> 217 <div class="card-box"> 218 <div class="icon-wrapper"> 219 <span class="mbr-iconfont mobi-mbri-smile-face mobi-mbri"></span> 220 </div> 221 <h4 class="item-title mbr-fonts-style display-7"><strong>Apply the hologenomic framework</strong></h4> 222 <p class="mbr-text mbr-fonts-style display-4">and research approaches towards enhancing human health and animal production systems.<br></p> 223 </div> 224 </div> 225 </div> 226 227 </div> 228 </div> 229 </div> 230 </div> 231</section> 232 233<section data-bs-version="5.1" class="features02 divem5 cid-ulGlK85B0e" id="features02-13"> 234 235 236 237 238 239 <div class="container"> 240 <div class="row flex-row-reverse"> 241 <div class="col-12 col-lg-4"> 242 <div class="title-wrapper"> 243 <h2 class="mbr-section-title mbr-fonts-style display-5"> 244 <strong>Training objectives</strong></h2> 245 </div> 246 </div> 247 <div class="col-12 col-lg-8"> 248 <div class="items"> 249 <div class="item features-without-image item-mb"> 250 <div class="item-wrapper"> 251 <div class="card-box"> 252 <div class="icon-wrapper">
253 <span class="mbr-iconfont mobi-mbri-left-right mobi-mbri"></span> 254 </div> 255 <h4 class="item-title mbr-fonts-style display-7"><strong>Understand the relevance of host-microbiota interactions</strong></h4> 256 <p class="mbr-text mbr-fonts-style display-4">and master the approaches to implement hologenomics to answer diverse research questions.<br></p> 257 </div> 258 </div> 259 </div> 260 <div class="item features-without-image item-mb"> 261 <div class="item-wrapper"> 262 <div class="card-box"> 263 <div class="icon-wrapper"> 264 <span class="mbr-iconfont mobi-mbri-growing-chart mobi-mbri"></span> 265 </div> 266 <h4 class="item-title mbr-fonts-style display-7"><strong>Develop skills in quantitative analysis and management of big data</strong></h4> 267 <p class="mbr-text mbr-fonts-style display-4"> 268 to be able to tackle the 21st-century research challenges beyond genomics, metagenomics and hologenomics. 269 </p> 270 </div> 271 </div> 272 </div> 273 <div class="item features-without-image item-mb"> 274 <div class="item-wrapper"> 275 <div class="card-box"> 276 <div class="icon-wrapper"> 277 <span class="mbr-iconfont mobi-mbri-users mobi-mbri"></span> 278 </div> 279 <h4 class="item-title mbr-fonts-style display-7"><strong>Acquire the necessary transferable skills to ensure successful progress in academia and industry</strong></h4> 280 <p class="mbr-text mbr-fonts-style display-4">and effective interaction with other stakeholders, such as private companies, policy makers and the general public.<br></p> 281 </div> 282 </div> 283 </div> 284 285 </div> 286 </div> 287 </div> 288 </div> 289</section> 290 291<section data-bs-version="5.1" class="features02 divem5 cid-ulGmksNGvW" id="features02-14"> 292 293 294 295 296 297 <div class="container"> 298 <div class="row"> 299 <div class="col-12 col-lg-4"> 300 <div class="title-wrapper"> 301 <h2 class="mbr-section-title mbr-fonts-style display-5"> 302 <strong>Strategic objectives</strong></h2> 303 </div> 304 </div> 305 <div class="col-12 col-lg-8"> 306 <div class="items"> 307 <div class="item features-without-image item-mb"> 308 <div class="item-wrapper"> 309 <div class="card-box"> 310 <div class="icon-wrapper"> 311 <span class="mbr-iconfont mobi-mbri-rocket mobi-mbri"></span> 312 </div> 313 <h4 class="item-title mbr-fonts-style display-7"><strong>Train the next generation of multidisciplinary scientists</strong></h4> 314 <p class="mbr-text mbr-fonts-style display-4">that will be equipped with the skills to exploit the latest biomolecular technologies with which to grapple with the current and future societal challenges.<br></p> 315 </div> 316 </div> 317 </div> 318 <div class="item features-without-image item-mb"> 319 <div class="item-wrapper"> 320 <div class="card-box"> 321 <div class="icon-wrapper"> 322 <span class="mbr-iconfont mobi-mbri-l
322ike mobi-mbri"></span> 323 </div> 324 <h4 class="item-title mbr-fonts-style display-7"><strong>Strengthen both European industry and academia</strong></h4> 325 <p class="mbr-text mbr-fonts-style display-4">with a cohort of talented, closely-knit researchers with the attributes to become international leaders in their chosen fields.<br></p> 326 </div> 327 </div> 328 </div> 329 <div class="item features-without-image item-mb"> 330 <div class="item-wrapper"> 331 <div class="card-box"> 332 <div class="icon-wrapper"> 333 <span class="mbr-iconfont mobi-mbri-contact-form mobi-mbri"></span> 334 </div> 335 <h4 class="item-title mbr-fonts-style display-7"><strong>Produce a large number of high-profile publications</strong></h4> 336 <p class="mbr-text mbr-fonts-style display-4"> 337 and stimulate future research to create future world-leading scholars and advance the field of hologenomics beyond the current scope of the project. 338 </p> 339 </div> 340 </div> 341 </div> 342 <div class="item features-without-image item-mb"> 343 <div class="item-wrapper"> 344 <div class="card-box"> 345 <div class="icon-wrapper"> 346 <span class="mbr-iconfont mobi-mbri-share mobi-mbri"></span> 347 </div> 348 <h4 class="item-title mbr-fonts-style display-7"><strong>Enable long-term transfer of technological gains</strong></h4> 349 <p class="mbr-text mbr-fonts-style display-4">to and from industry partners, leading to development of new products and services.<br></p> 350 </div> 351 </div> 352 </div> 353 </div> 354 </div> 355 </div> 356 </div> 357</section> 358 359<section data-bs-version="5.1" class="footer01 divem5 cid-ulCUPQgLkT" once="footers" id="footer01-8"> 360 361 362 363 364 365 <div class="container-fluid"> 366 <div class="row"> 367 368 369 <div class="col-12"> 370 <div class="copy-wrapper"> 371 <a class="logo-wrapper" href="#"> 372 <img src="assets/images/eu-flag-120x80.jpg" alt="Mobirise"> 373 <p class="mbr-brand mbr-fonts-style display-7"> 374 <strong>Funded by the European Union under Grant Agreement </strong>101169005</p> 375 </a> 376 <p class="mbr-copy mbr-fonts-style display-4"> 377 HoloGen Consortium 2026</p> 378 </div> 379 </div> 380 </div> 381 </div> 382</section> 383 384
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