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91                <h1 class="mbr-section-title mbr-fonts-style mb-0 display-1">
92                    Concept</h1>
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94            </div>
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98</section>
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100<section data-bs-version="5.1" class="article01 divem5 cid-ulD5i35J8X" id="article01-a">
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116                    <h2 class="mbr-section-title mbr-fonts-style display-2">
117                        <strong>HOLOGENOMICS</strong></h2>
118                    <p class="mbr-text mbr-fonts-style display-5">
119                        relies on the generation and analysis of host genomic and microbial metagenomic data to detect the interactions between them and identify the biological impact of such interactions on both hosts and associated microorganism communities.
120                    </p>
121                    
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123            </div>
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126</section>
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128<section data-bs-version="5.1" class="features03 merchm5 cid-ulGntcmVoY" id="features03-15">
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134    <div class="container">
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141                    <div class="item features-without-image item-mb">
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144                                <h4 class="item-title mbr-fonts-style display-5">
145                                    Host-microbe interactions</h4>
146                                <p class="item-text mbr-fonts-style display-7">
147                                    The core of <strong>HoloGen</strong> revolves around the idea that a macroscopic organism, be it fungi, animal (including humans) or plant, can be viewed as an emergent property of interactions between that organism - i.e. host - and the microbes living on and inside it.&nbsp;Many biological processes in animals and their associated microorganisms are affected or modulated through such a symbiotic relationship. </p>
148                            </div>
149                        </div>
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154                                <h4 class="item-title mbr-fonts-style display-5">
155                                    Analytical technologies<br></h4>
156                                <p class="item-text mbr-fonts-style display-7">
157                                    The recent development of high throughput biomolecular data generation platforms and <br>
157 the improvement of data processing infrastructures, it is now possible to screen virtually the entire biochemical landscape where hosts and microorganisms interact. This necessitates a truly multidisciplinary approach consisting of the analysis of genomes, transcriptomes, proteomes and metabolomes of both animals and their associated microorganisms.</p>
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159                        </div>
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165                                    A one-health approach</h4>
166                                <p class="item-text mbr-fonts-style display-7"><strong>
167                                    HoloGen</strong> targets significant, ground-breaking scientific advancement in our knowledge about functional interconnections between hosts and microbiomes through its use of cutting-edge omics-based measurements of molecular states coupled with novel computational approaches, to address scientific questions regarding human and animal health, agricultural production, microbial ecology,&nbsp; and more.</p>
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175</section>
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177<section data-bs-version="5.1" class="features02 divem5 cid-ulGl04L1cC" id="features02-11">
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183    <div class="container">
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185            <div class="col-12 col-lg-4">
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187                    <h2 class="mbr-section-title mbr-fonts-style display-5">
188                        <strong>Research Objectives</strong></h2>
189                </div>
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191            <div class="col-12 col-lg-8">
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199                                <h4 class="item-title mbr-fonts-style display-7"><strong>Develop novel computational approaches</strong></h4>
200                                <p class="mbr-text mbr-fonts-style display-4">to model the biochemical, genetic, temporal and spatial levels of host-microbiota interactions in hologenomic research.<br></p>
201                            </div>
202                        </div>
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204                    <div class="item features-without-image item-mb">
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208                                    <span class="mbr-iconfont mobi-mbri-update mobi-mbri"></span>
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210                                <h4 class="item-title mbr-fonts-style display-7"><strong>Understand fundamental principles of biochemical and ecological interplay</strong></h4>
211                                <p class="mbr-text mbr-fonts-style display-4">between animal hosts and their associated microorganisms through applying a hologenomic perspective.<br></p>
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213                        </div>
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221                                <h4 class="item-title mbr-fonts-style display-7"><strong>Apply the hologenomic framework</strong></h4>
222                                <p class="mbr-text mbr-fonts-style display-4">and research approaches towards enhancing human health and animal production systems.<br></p>
223                            </div>
224                        </div>
225                    </div>
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233<section data-bs-version="5.1" class="features02 divem5 cid-ulGlK85B0e" id="features02-13">
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243                    <h2 class="mbr-section-title mbr-fonts-style display-5">
244                        <strong>Training objectives</strong></h2>
245                </div>
246            </div>
247            <div class="col-12 col-lg-8">
248                <div class="items">
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253                                    <span class="mbr-iconfont mobi-mbri-left-right mobi-mbri"></span>
254                                </div>
255                                <h4 class="item-title mbr-fonts-style display-7"><strong>Understand the relevance of host-microbiota interactions</strong></h4>
256                                <p class="mbr-text mbr-fonts-style display-4">and master the approaches to implement hologenomics to answer diverse research questions.<br></p>
257                            </div>
258                        </div>
259                    </div>
260                    <div class="item features-without-image item-mb">
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263                                <div class="icon-wrapper">
264                                    <span class="mbr-iconfont mobi-mbri-growing-chart mobi-mbri"></span>
265                                </div>
266                                <h4 class="item-title mbr-fonts-style display-7"><strong>Develop skills in quantitative analysis and management of big data</strong></h4>
267                                <p class="mbr-text mbr-fonts-style display-4">
268                                    to be able to tackle the 21st-century research challenges beyond genomics, metagenomics and hologenomics.
269                                </p>
270                            </div>
271                        </div>
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279                                <h4 class="item-title mbr-fonts-style display-7"><strong>Acquire the necessary transferable skills to ensure successful progress in academia and industry</strong></h4>
280                                <p class="mbr-text mbr-fonts-style display-4">and effective interaction with other stakeholders, such as private companies, policy makers and the general public.<br></p>
281                            </div>
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291<section data-bs-version="5.1" class="features02 divem5 cid-ulGmksNGvW" id="features02-14">
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299            <div class="col-12 col-lg-4">
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301                    <h2 class="mbr-section-title mbr-fonts-style display-5">
302                        <strong>Strategic objectives</strong></h2>
303                </div>
304            </div>
305            <div class="col-12 col-lg-8">
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311                                    <span class="mbr-iconfont mobi-mbri-rocket mobi-mbri"></span>
312                                </div>
313                                <h4 class="item-title mbr-fonts-style display-7"><strong>Train the next generation of multidisciplinary scientists</strong></h4>
314                                <p class="mbr-text mbr-fonts-style display-4">that will be equipped with the skills to exploit the latest biomolecular technologies with which to grapple with the current and future societal challenges.<br></p>
315                            </div>
316                        </div>
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324                                <h4 class="item-title mbr-fonts-style display-7"><strong>Strengthen both European industry and academia</strong></h4>
325                                <p class="mbr-text mbr-fonts-style display-4">with a cohort of talented, closely-knit researchers with the attributes to become international leaders in their chosen fields.<br></p>
326                            </div>
327                        </div>
328                    </div>
329                    <div class="item features-without-image item-mb">
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333                                    <span class="mbr-iconfont mobi-mbri-contact-form mobi-mbri"></span>
334                                </div>
335                                <h4 class="item-title mbr-fonts-style display-7"><strong>Produce a large number of high-profile publications</strong></h4>
336                                <p class="mbr-text mbr-fonts-style display-4">
337                                    and stimulate future research to create future world-leading scholars and advance the field of hologenomics beyond the current scope of the project.
338                                </p>
339                            </div>
340                        </div>
341                    </div>
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348                                <h4 class="item-title mbr-fonts-style display-7"><strong>Enable long-term transfer of technological gains</strong></h4>
349                                <p class="mbr-text mbr-fonts-style display-4">to and from industry partners, leading to development of new products and services.<br></p>
350                            </div>
351                        </div>
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353                </div>
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