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131<script type="application/ld+json">{"@context": "https://schema.org", 132"@type": "MedicalWebPage", 133"audience": "Patient", 134"specialty": "Renal", 135"url": "https://www.jynarque.com/why-jynarque", 136"headline": ["Why JYNARQUE® (tolvaptan)?","Push back the progression of your ADPKD","With JYNARQUE, help slow the progression of your diseaseâacross CKD stages","Patients taking JYNARQUE experienced less kidney pain"], 137"abstract": "For adults who are at risk for rapidly progressing ADPKD, JYNARQUE® (tolvaptan) is the only FDA-approved treatment that works to slow the decline of kidney function. 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446-item"> 447 <a href="#"><span>About JYNARQUE</span></a> 448 <ul class="menu nav"> 449 <li class="menu-item menu-item-1 nav-item"> 450 <a href="understanding-adpkd-progression.html" data-drupal-link-system-path="node/37481">Understanding ADPKD & Progression</a> 451 </li> 452 <li class="menu-item menu-item-2 menu-item--active-trail nav-item"> 453 <a href="why-jynarque.html" data-drupal-link-system-path="node/6" class="is-active" aria-current="page">Why JYNARQUE?</a> 454 </li> 455 <li class="menu-item menu-item-3 nav-item"> 456 <a href="how-jynarque-works.html" data-drupal-link-system-path="node/26">How JYNARQUE Works</a> 457 </li> 458 <li class="menu-item menu-item-4 nav-item"> 459 <a href="side-effects-rems.html" data-drupal-link-system-path="node/25741">JYNARQUE Side Effects and REMS</a> 460 </li> 461 <li class="menu-item menu-item-5 nav-item"> 462 <a href="is-jynarque-for-you.html" data-drupal-link-system-path="node/25746">See if JYNARQUE is Right for You</a> 463 </li> 464 </ul> 465 466 </li> 467 <li class="menu-item menu-item-2 menu-item--expanded nav-item"> 468 <a href="#"><span>Getting Started</span></a> 469 <ul class="menu nav"> 470 <li class="menu-item menu-item-1 nav-item"> 471 <a href="how-to-get-started.html" data-drupal-link-system-path="node/36">How to Get Started</a> 472 </li> 473 <li class="menu-item menu-item-2 nav-item"> 474 <a href="risks-and-rems.html" data-drupal-link-system-path="node/25736">REMS: Lab Work and Monitoring</a> 475 </li> 476 <li class="menu-item menu-item-3 nav-item"> 477 <a href="specialty-pharmacy.html" data-drupal-link-system-path="node/15816">Working With a Specialty Pharmacy</a> 478 </li> 479 <li class="menu-item menu-item-4 nav-item"> 480 <a href="how-to-take-jynarque.html" data-drupal-link-system-path="node/25726">How to Take JYNARQUE</a> 481 </li> 482 </ul> 483 484 </li> 485 <li class="menu-item menu-item-3 nav-item"> 486 <a href="tips-while-on-treatment.html" data-drupal-link-system-path="node/31">Tips While on Treatment</a> 487 </li> 488 <li class="menu-item menu-item-4 menu-item--expanded nav-item"> 489 <a href="#"><span>Resources</span></a> 490 <ul class="menu nav"> 491 <li class="menu-item menu-item-1 nav-item"> 492 <a href="online-resources.html" data-drupal-link-system-path="node/25831">Online Resources</a> 493 </li> 494 <li class="menu-item menu-item-2 nav-item"> 495 <a href="downloadable-resources.html" data-drupal-link-system-path="node/25721">Downloadable Resources</a> 496 </li> 497 </ul> 498 499 </li> 500 </ul> 501 502 503 504 </nav> 505 506 <a href="#" class="mobile-menu-open-btn" data-test='mobile-menu-toggle'> 507 <span>Mobile menu</span> 508 </a> 509 <a href="#" class="mobile-menu-close-btn"> 510 <span>Mobile menu</span> 511 </a> 512 </div> 513 514 </div> 515 </div> 516 </header> 517 518 <div id="mobile-menu" class="region--mobile-menu" data-analytics-position="header"> 519 <div class="container"> 520 <div class="region region-mobile-menu clearfix"> 521 <nav role="navigation" aria-labelledby="block-mainnavigation-menu" id="block-mainnavigation"> 522 523 <h2 class="visually-hidden" id="block-mainnavigation-menu">Main navigation</h2> 524 525 526 527 <ul data-block="block-mainnavigation" data-test="main-menu" class="menu menu-main nav"> 528 <li class="menu-item menu-item-1 menu-item--expanded menu-item--active-trail nav
528-item"> 529 <a href="#"><span>About JYNARQUE</span></a> 530 <ul class="menu nav"> 531 <li class="menu-item menu-item-1 nav-item"> 532 <a href="understanding-adpkd-progression.html" data-drupal-link-system-path="node/37481">Understanding ADPKD & Progression</a> 533 </li> 534 <li class="menu-item menu-item-2 menu-item--active-trail nav-item"> 535 <a href="why-jynarque.html" data-drupal-link-system-path="node/6" class="is-active" aria-current="page">Why JYNARQUE?</a> 536 </li> 537 <li class="menu-item menu-item-3 nav-item"> 538 <a href="how-jynarque-works.html" data-drupal-link-system-path="node/26">How JYNARQUE Works</a> 539 </li> 540 <li class="menu-item menu-item-4 nav-item"> 541 <a href="side-effects-rems.html" data-drupal-link-system-path="node/25741">JYNARQUE Side Effects and REMS</a> 542 </li> 543 <li class="menu-item menu-item-5 nav-item"> 544 <a href="is-jynarque-for-you.html" data-drupal-link-system-path="node/25746">See if JYNARQUE is Right for You</a> 545 </li> 546 </ul> 547 548 </li> 549 <li class="menu-item menu-item-2 menu-item--expanded nav-item"> 550 <a href="#"><span>Getting Started</span></a> 551 <ul class="menu nav"> 552 <li class="menu-item menu-item-1 nav-item"> 553 <a href="how-to-get-started.html" data-drupal-link-system-path="node/36">How to Get Started</a> 554 </li> 555 <li class="menu-item menu-item-2 nav-item"> 556 <a href="risks-and-rems.html" data-drupal-link-system-path="node/25736">REMS: Lab Work and Monitoring</a> 557 </li> 558 <li class="menu-item menu-item-3 nav-item"> 559 <a href="specialty-pharmacy.html" data-drupal-link-system-path="node/15816">Working With a Specialty Pharmacy</a> 560 </li> 561 <li class="menu-item menu-item-4 nav-item"> 562 <a href="how-to-take-jynarque.html" data-drupal-link-system-path="node/25726">How to Take JYNARQUE</a> 563 </li> 564 </ul> 565 566 </li> 567 <li class="menu-item menu-item-3 nav-item"> 568 <a href="tips-while-on-treatment.html" data-drupal-link-system-path="node/31">Tips While on Treatment</a> 569 </li> 570 <li class="menu-item menu-item-4 menu-item--expanded nav-item"> 571 <a href="#"><span>Resources</span></a> 572 <ul class="menu nav"> 573 <li class="menu-item menu-item-1 nav-item"> 574 <a href="online-resources.html" data-drupal-link-system-path="node/25831">Online Resources</a> 575 </li> 576 <li class="menu-item menu-item-2 nav-item"> 577 <a href="downloadable-resources.html" data-drupal-link-system-path="node/25721">Downloadable Resources</a> 578 </li> 579 </ul> 580 581 </li> 582 </ul> 583 584 585 586 </nav> 587 588 </div> 589 590 </div> 591 </div> 592 <section aria-label="Header Information"> 593 <div id="header-info" class="region--header-info"> 594 <div class="container"> 595 <div class="region region-header-info clearfix"> 596 <div id="block-jynarque-hcc-2021-headertextdescription" class="block-content-header-text-description block-content-basic block block-block-content block-block-content855941ea-329b-4a19-bc10-2bd1df83da5c block-header-text-description"> 597 598 599 <div class="content"> 600 601 602 603 604 605 606 <div class="field field--name-body field--type-text-with-summary field--label-hidden"> 607 <div class="field--item"><p>Proven to slow kidney function decline in adults who are at risk for rapidly progressing ADPKD</p></div> 608 </div> 609 610 611 </div> 612 </div> 613 614 </div> 615 616 </div> 617 </div> 618 </section> 619 620 621 <main role="main" class="main-content" id="main-content"> 622 <div class="container"> 623 <div class="region region-highlighted clearfix"> 624 <div data-drupal-messages-fallback class="hidden"></div> 625 626 </div> 627 628 </div> 629 <div class="no-sidebar"> 630 <div class="region region-content clearfix">
631 <div id="block-jynarque-hcc-2021-content" class="block block-system block-system-main-block"> 632 633 634 <div class="content"> 635 636 637<article data-history-node-id="6" about="/why-jynarque" class="node node-type-landing-page node-view-mode-full"> 638 639 640 641 642 643 <div class="hero-section"> 644 645 646 </div> 647 648 <div class="node-content"> 649 650 651 652 653<div class="field field--name-field-formatted-title field--type-text-long field--label-hidden container" data-test='paragraph'> 654 <div class="field--item"> 655 <h1 class="title-inline-line"><span>Why</span> <span><strong>JYNARQUE<sup>®</sup> (tolvaptan)?</strong></span></h1> 656 657 </div> 658 </div> 659 660 661 662 663 664 665 <div class="field field--name-field-paragraphs field--type-entity-reference-revisions field--label-hidden"> 666 <div class="field--item"> <div class="container clearfix paragraph paragraph--type--wrapper paragraph--view-mode--default why-jynarque-subtitle-block" id="paragraph-2646" data-test='paragraph'> 667 668 669 670 671 672 <h2><strong>Push back the progression of your ADPKD with JYNARQUE</strong></h2> 673 674 675 676 677 678 679 680 681 <div class="field field--name-field-paragraphs field--type-entity-reference-revisions field--label-hidden"> 682 <div class="field--item"> <div class="clearfix paragraph paragraph--type--text paragraph--view-mode--default" id="paragraph-2641" > 683 684 685 686 687 688 689 <div class="field field--name-field-text field--type-text-long field--label-hidden"> 690 <div class="field--item"><p>Tolvaptan is a <span class="blue-text font-weight-bold">recommended treatment</span> by the KDIGO Clinical Practice Guideline for the Evaluation, Management, and Treatment of ADPKD. The guidelines offer clear, research-based recommendations to help patients and doctors make informed decisions.</p></div> 691 </div> 692 693 694 </div> 695</div> 696 </div> 697 698 699 </div> 700</div> 701 <div class="field--item"> <div class="clearfix paragraph paragraph--type--from-library paragraph--view-mode--default" id="paragraph-2281" data-test='paragraph'> 702 703 704 705 706 707 708 <div class="field field--name-paragraphs field--type-entity-reference-revisions field--label-hidden"> 709 <div class="field--item"> <div class="clearfix paragraph paragraph--type--wrapper paragraph--view-mode--default h-100 bigger-container" id="paragraph-2276" > 710 <div class="container"> 711 <div class="row"> 712 713 714 715 716 717 718 <div class="col-12 clearfix paragraph paragraph--type--wrapper paragraph--view-mode--default" id="paragraph-2271" > 719 720 721 722 723 724 <h2 class="font-weight-normal">JYNARQUE slowed the decline of kidney function by</h2> 725 726 727 728 729 730 731 <div class="clearfix paragraph paragraph--type--persentage-text-top paragraph--view-mode--default" id="paragraph-2266" > 732 <div class="percentage_text_top"> 733 <div class="percentage_text_top__top_section"> 734 735 736 737 738 739 740 <div class="field field--name-field-left-percentage field--type-text field--label-hidden"> 741 <div class="field--item">35<sup>%</sup></div> 742 </div> 743 744 745 <div class="percentage_text_top__top_section--content"> 746 747 748 749 750 751 752 <div class="field field--name-field-left-text field--type-text-long field--label-hidden"> 753 <div class="field--item"><p>as seen in REPRISE, a 1-year clinical study of patients with<br class="desktop-only"> 754CKD stages 2 to 4, vs placebo*</p> 755</div> 756 </div> 757 758 759 760 <div class="d-none d-md-block"> 761 762 763 764 765 766 767 <div class="field field--name-field-left-footnote field--type-text-long field--label-hidden"> 768 <div class="field--item"><p class="footnote mt-lg-2 mb-0">Treatment effect: 1.3 mL/min/1.73 m<sup>2</sup>â/âyear (95% Cl: 0.86-1.68, <em>P</em><.0001).<br class="desktop-only"> 769-2.3 mL/min/1.73 m<sup>2</sup>ââ/year with JYNARQUE vs -3.6 mL/min/1.73 m<sup>2</sup>ââ/âyear with placebo.</p> 770</div> 771 </div> 772 773 774 </div> 775 </div> 776 <div class="d-md-none"> 777 778 779 780 781 782 783 <div class="field field--name-field-left-footnote field--type-text-long field--label-hidden"> 784 <div class="field--item"><p class="footnote mt-lg-2 mb-0">Treatment effect: 1.3 mL/min/1.73 m<sup>2</sup>â/âyear (95% Cl: 0.86-1.68, <em>P</em><.0001).<br class="desktop-only"> 785-2.3 mL/min/1.73 m<sup>2</sup>ââ/year with JYNARQUE vs -3.6 mL/min/1.73 m<sup>2</sup>ââ/âyear with placebo.</p> 786</div> 787 </div> 788 789 790 </div> 791 </div> 792 <div class="percentage_text_top__bottom_section"> 793 794 795 796 797 798 799 <div class="field field--name-field-right-percentage field--type-text field--label-hidden"> 800 <div class="field--item">26<sup>%</sup></div> 801 </div> 802 803 804 <div class="percentage_text_top__bottom_section--content"> 805 806 807 808 809 810 811 <div class="field field--name-field-right-text field--type-text-long field--label-hidden"> 812 <div class="field--item"><p>as seen in TEMPO 3:4, a 3-year clinical study of patients<br class="desktop-only"> 813with CKD stages 1 to 3, vs placebo*</p> 814</div> 815 </div> 816 817 818 819 <div class="d-none d-md-block"> 820 821 822 823 824 825 826 <div class="field field--name-field-right-footnote field--type-text-long field--label-hidden"> 827 <div class="field--item"><p class="footnote mt-lg-2">Treatment effect: 1.0 mL/min/1.73 m<sup>2</sup>â/âyear (95% CI: 0.6-1.4, <em>P</em><.001).<br class="desktop-only"> 828-2.7 mL/min/1.73 m<sup>2</sup>ââ/year with JYNARQUE vs -3.7 mL/min/1.73 m<sup>2</sup>ââ/âyear with placebo.</p> 829</div> 830 </div> 831 832 833 </div> 834 </div> 835 <div class="d-md-none"> 836 837 838 839 840 841 842 <div class="field field--name-field-right-footnote field--type-text-long field--label-hidden"> 843 <div class="field--item"><p class="footnote mt-lg-2">Treatment effect: 1.0 mL/min/1.73 m<sup>2</sup>â/âyear (95% CI: 0.6-1.4, <em>P</em><.001).<br class="desktop-only"> 844-2.7 mL/min/1.73 m<sup>2</sup>ââ/year with JYNARQUE vs -3.7 mL/min/1.73 m<sup>2</sup>ââ/âyear with placebo.</p> 845</div> 846 </div> 847 848 849 </div> 850 </div> 851 <div class="percentage_text_top__central-line"></div> 852 <div class="percentage_text_top__horizontal-line"></div> 853 </div> 854 </div> 855 856 857 </div> 858 859 860 </div> 861 </div> 862 </div> 863</div> 864 </div> 865 866 867 </div> 868</div> 869 <div class="field--item"> <div class="container clearfix paragraph paragraph--type--wrapper paragraph--view-mode--default" id="paragraph-2636" data-test='paragraph'> 870 871 872 873 874 875 <h2 class="pt-2 pt-lg-0 mt-4 mt-lg-5">With JYNARQUE, help slow the progression of your diseaseâacross CKD stages</h2> 876 877 878 879 880 881 882 883 884 <div class="field field--name-field-paragraphs field--type-entity-reference-revisions field--label-hidden"> 885 <div class="field--item"> <div class="border-blue-block ckd-stages clearfix paragraph paragraph--type--wrapper paragraph--view-mode--default" style="background-color:#FFFBEF" id="paragraph-2181" > 886 887 888 889 890 891 892 893 894 <div class="field field--name-field-paragraphs field--type-entity-reference-revisions field--label-hidden"> 895 <div class="field--item"> <div class="clearfix paragraph paragraph--type--text paragraph--view-mode--default" id="paragraph-2171" > 896 897 898 899 900 901 902 <div class="field field--name-field-text field--type-text-long field--label-hidden"> 903 <div class="field--item"><p>JYNARQUE is appropriate for adults who are at risk for rapidly progressing ADPKD, throughout CKD stages 1 to 4</p></div> 904 </div> 905 906 907 </div> 908</div> 909 <div class="field--item"> <div class="classy-desktop-only clearfix paragraph paragraph--type--inline-svg-image paragraph--view-mode--default" id="paragraph-2176" > 910 911 912 913 914 915 <h3 class="text-center">STAGES OF CKD</h3> 916 917 918 919 920 921 <div> 922 923 924 925 926 927 928 <svg xmlns="http://www.w3.org/2000/svg" width="501" height="90" viewBox="0 0 501 90" fill="none" aria-label="Stages of CKD"> 929 <path d="M372.684 25.1133H254.776V65.7711H372.684V25.1133Z" fill="#003A70"></path> 930 <path d="M373.665 66.7535H253.935V24.1328H373.665V66.7535ZM255.758 64.9309H371.843V26.0956H255.758V64.9309Z" fill="#FCC531"></path> 931 <path d="M499.284 25.1133H381.376V65.7711H499.284V25.1133Z" fill="#003A70"></path> 932 <path d="M500.266 66.7535H380.535V24.1328H500.266V66.7535ZM382.358 64.9309H498.443V26.0956H382.358V64.9309Z" fill="#FCC531"></path> 933 <path d="M246.224 25.1133H128.316V65.7711H246.224V25.1133Z" fill="#003A70"></path> 934 <path d="M314.781 17.8242H312.959V8.85147H60.4596V17.8242H58.637V6.88867H314.781V17.8242Z" fill="#003A70"></path> 935 <path d="M239.074 0.298828H134.064V13.8982H239.074V0.298828Z" fill="#FFFCEF"></path> 936 <path d="M441.943 83.5781H185.798V72.6426H187.621V81.7555H440.12V72.6426H441.943
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class="classy-mobile-only clearfix paragraph paragraph--type--inline-svg-image paragraph--view-mode--default" id="paragraph-3411" > 968 969 970 971 972 973 <h3 class="text-center">STAGES OF CKD</h3> 974 975 976 977 978 979 <div> 980 981 982 983 984 985 986 <svg xmlns="http://www.w3.org/2000/svg" width="304" height="88" viewBox="0 0 304 88" fill="none" aria-label="Stages of CKD"> 987 <path d="M35 21.498V11.5273H60.7322" stroke="#103B71" stroke-width="2"></path> 988 <path d="M70.0727 17.2514V9.1198H67.5491V5.47461H77.2228V9.1198H74.6992V17.2514H70.0727Z" fill="#003A70"></path> 989 <path d="M78.3445 5.33594C81.4289 5.33594 84.6535 5.33594 87.7379 5.33594V8.84093H82.8309V9.68212H87.4574V12.9067H82.8309V13.7479H87.7379V17.2529C84.6535 17.2529 81.4289 17.2529 78.3445 17.2529V5.33594Z" fill="#003A70"></path> 990 <path d="M94.0467 14.5876V17.2514H89.5603V5.47461C90.9623 5.47461 92.5045 5.47461 94.0467 5.47461L96.4301 8.8394L98.8135 5.47461C100.215 5.47461 101.758 5.47461 103.3 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999 <path d="M34.1589 50.4468V46.5212L34.2991 43.8574L33.3177 44.8388L30.7941 41.8946L35.0001 37.4082H39.206V50.587H34.1589V50.4468Z" fill="white"></path> 1000 <rect x="78.5" y="26.998" width="69" height="34" fill="#103B71"></rect> 1001 <rect x="78.5" y="26.998" width="69" height="34" stroke="#FFC52E"></rect> 1002 <path d="M112.369 42.1755H107.602V42.0353C107.602 38.6706 110.266 37.2686 113.07 37.2686C115.874 37.2686 118.398 38.6705 118.398 41.6147C118.398 43.9981 116.996 45.4001 115.453 46.8021H118.398V50.7277H107.602V47.3629C108.443 46.6619 113.21 42.5961 113.491 42.0353C113.631 41.6147 113.491 41.3343 113.21 41.3343C112.93 41.1941 112.509 41.4745 112.509 42.0353V42.1755H112.369Z" fill="white"></path> 1003 <rect x="156.5" y="26.998" width="69" height="34" fill="#103B71"></rect> 1004 <rect x="156.5" y="26.998" width="69" height="34" stroke="#FFC52E"></rect> 1005 <path d="M189.878 46.1007C189.878 47.2223 191.421 47.2223 191.421 46.2409C191.421 45.8203 191.14 45.3997 190.72 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paragraph--view-mode--default" style="background-color:#FFFBEF" id="paragraph-2581" data-test='paragraph'> 1036 <div class="container"> 1037 <div class="row"> 1038 1039 1040 1041 1042 1043
1044 <div class="col-xl-3 col-lg-5 clearfix paragraph paragraph--type--wrapper paragraph--view-mode--default image-edge-left" id="paragraph-3426" > 1045 1046 1047 1048 1049 1050 1051 1052 1053 <div class="field field--name-field-paragraphs field--type-entity-reference-revisions field--label-hidden"> 1054 <div class="field--item"> <div class="classy-desktop-only clearfix paragraph paragraph--type--image paragraph--view-mode--default" id="paragraph-2751" > 1055 1056 1057 1058 1059 1060 <div> 1061 1062 1063 1064 1065 1066 1067 <picture> 1068 <source srcset="sites/g/files/qhldwo12166/files/styles/max_2600x2600/public/2025-10/less-kidney-pain-desktop.png" type="image/webp" sizes="100vw" width="790" height="642"/> 1069 <source srcset="sites/g/files/qhldwo12166/files/styles/max_2600x2600/public/2025-10/less-kidney-pain-desktop.png" type="image/png" sizes="100vw" width="790" height="642"/> 1070 <img loading="eager" srcset="sites/g/files/qhldwo12166/files/styles/max_2600x2600/public/2025-10/less-kidney-pain-desktop.png" sizes="100vw" width="790" height="642" src="sites/g/files/qhldwo12166/files/styles/max_1440x1440/public/2025-10/less-kidney-pain-desktop.png" alt="" typeof="foaf:Image" class="img-fluid" /> 1071 1072 </picture> 1073 1074 1075 1076</div> 1077 1078 1079 </div> 1080</div> 1081 <div class="field--item"> <div class="classy-mobile-only clearfix paragraph paragraph--type--image paragraph--view-mode--default" id="paragraph-5776" > 1082 1083 1084 1085 1086 1087 <div> 1088 1089 1090 1091 1092 1093 1094 <picture> 1095 <source srcset="sites/g/files/qhldwo12166/files/styles/max_2600x2600/public/2025-10/less-kidney-pain-mobile.png" type="image/webp" sizes="100vw" width="720" height="642"/> 1096 <source srcset="sites/g/files/qhldwo12166/files/styles/max_2600x2600/public/2025-10/less-kidney-pain-mobile.png" type="image/png" sizes="100vw" width="720" height="642"/> 1097 <img loading="eager" srcset="sites/g/files/qhldwo12166/files/styles/max_2600x2600/public/2025-10/less-kidney-pain-mobile.png" sizes="100vw" width="720" height="642" src="sites/g/files/qhldwo12166/files/styles/max_1440x1440/public/2025-10/less-kidney-pain-mobile.png" alt="" typeof="foaf:Image" class="img-fluid" /> 1098 1099 </picture> 1100 1101 1102 1103</div> 1104 1105 1106 </div> 1107</div> 1108 </div> 1109 1110 1111 </div> 1112 1113 <div class="col-xl-9 col-lg-7 clearfix paragraph paragraph--type--wrapper paragraph--view-mode--default align-content-center" id="paragraph-2596" > 1114 1115 1116 1117 1118 1119 1120 1121 1122 <div class="field field--name-field-paragraphs field--type-entity-reference-revisions field--label-hidden"> 1123 <div class="field--item"> <div class="clearfix paragraph paragraph--type--text paragraph--view-mode--default" id="paragraph-2586" > 1124 1125 1126 1127 1128 1129 1130 <div class="field field--name-field-text field--type-text-long field--label-hidden"> 1131 <div class="field--item"><h2 class="pt-1 pt-lg-0 mt-4 mt-lg-2 mb-lg-1 mb-xl-3 font-weight-normal">Patients taking JYNARQUE experienced less kidney pain</h2><p>In a clinical trial of patients with ADPKD, at CKD stages 1 to 3, those taking JYNARQUE were likely to experience</p></div> 1132 </div> 1133 1134 1135 </div> 1136</div> 1137 <div class="field--item"> <div class="percentage clearfix paragraph paragraph--type--text paragraph--view-mode--default" id="paragraph-2571" > 1138 1139 1140 1141 1142 1143 1144 <div class="field field--name-field-text field--type-text-long field--label-hidden"> 1145 <div class="field--item"><div class="percentage-primary">36<sup>%</sup></div><div class="percentage-text align-self-center"><h3><span class="blue-text font-weight-normal">fewer pain events</span></h3><p>9.9% of patients taking JYNARQUE had a pain event vs 16.2% of those taking placebo</p></div></div> 1146 </div> 1147 1148 1149 </div> 1150</div> 1151 <div class="field--item"> <div class="footnote clearfix paragraph paragraph--type--text paragraph--view-mode--default" id="paragraph-2656" > 1152 1153 1154 1155 1156 1157 1158 <div class="field field--name-field-text field--type-text-long field--label-hidden"> 1159 <div class="field--item"><p><span style="white-space:pre-wrap;">Patient image is AI-generated.</span></p></div> 1160 </div> 1161 1162 1163 </div> 1164</div> 1165 <div class="field--item"> <div class="clearfix paragraph paragraph--type--text paragraph--view-mode--default" id="paragraph-2591" > 1166 1167 1168 1169 1170 1171 1172 <div class="field field--name-field-text field--type-text-long field--label-hidden"> 1173 <div class="field--item"><h3 class="mt-3 pt-1 mt-lg-3 pt-lg-3 mb-3 mb-lg-0 text-center text-lg-left px-3 px-lg-0 font-weight-normal">Talk to your nephrologist to see how you can slow the progression of your ADPKD today</h3></div> 1174 </div> 1175 1176 1177 </div> 1178</div> 1179 </div> 1180 1181 1182 </div> 1183 1184 1185 </div> 1186 </div> 1187 </div> 1188</div> 1189 <div class="field--item"> <div class="container clearfix paragraph paragraph--type--wrapper paragraph--view-mode--default" id="paragraph-2556" data-test='paragraph'> 1190 1191 1192 1193 1194 1195 1196 1197 1198 <div class="field field--name-field-paragraphs field--type-entity-reference-revisions field--label-hidden"> 1199 <div class="field--item"> <div class="clearfix paragraph paragraph--type--text paragraph--view-mode--default" id="paragraph-2551" > 1200 1201 1202 1203 1204 1205 1206 <div class="field field--name-field-text field--type-text-long field--label-hidden"> 1207 <div class="field--item"><p class="mb-0 pb-1 mb-lg-3 footnote">CKD=chronic kidney disease; FDA=Food and Drug Administration; KDGIO=Kidney Disease Improving Global Outcomes.</p><p class="mb-2 footnote"><span class="hang">*</span>Kidney function was measured by the change in the average eGFR over time.</p></div> 1208 </div> 1209 1210 1211 </div> 1212</div> 1213 </div> 1214 1215 1216 </div> 1217</div> 1218 <div class="field--item"> <div class="link-paragraph button clearfix paragraph paragraph--type--wrapper paragraph--view-mode--default" id="paragraph-2341" data-test='paragraph'> 1219 1220 1221 1222 1223 1224 1225 1226 1227 <div class="field field--name-field-paragraphs field--type-entity-reference-revisions field--label-hidden"> 1228 <div class="field--item"> <div class="clearfix paragraph paragraph--type--link paragraph--view-mode--default" id="paragraph-2336" > 1229 1230 1231 1232 1233 1234 1235 <div class="field field--name-field-link field--type-link field--label-hidden"> 1236 <div class="field--item"><a href="side-effects-rems.html">Learn about JYNARQUE side effects</a></div> 1237 </div> 1238 1239 1240 </div> 1241</div> 1242 </div> 1243 1244 1245 </div> 1246</div> 1247 <div class="field--item"> <div class="link-paragraph line clearfix paragraph paragraph--type--wrapper paragraph--view-mode--default" id="paragraph-2561" data-test='paragraph'> 1248 <div class="container"> 1249 1250 1251 1252 1253 1254 1255 1256 1257 <div class="field field--name-field-paragraphs field--type-entity-reference-revisions field--label-hidden"> 1258 <div class="field--item"> <div class="clearfix paragraph paragraph--type--link paragraph--view-mode--default" id="paragraph-2196" > 1259 1260 1261 1262 1263 1264 1265 <div class="field field--name-field-link field--type-link field--label-hidden"> 1266 <div class="field--item"><a href="how-jynarque-works.html">See how JYNARQUE works</a></div> 1267 </div> 1268 1269 1270 </div> 1271</div> 1272 </div> 1273 1274 1275 </div> 1276 </div> 1277</div> 1278 </div> 1279 1280 1281 </div> 1282 1283</article> 1284 1285 </div> 1286 </div> 1287 1288 </div> 1289 1290 </div> 1291 <div class="isi-page-wrapper"> 1292 <div class="container"> 1293 <div class="region region-isi clearfix"> 1294 1295 1296 1297 <a id="isi-top" name="isi-top"></a> 1298 <section id="inline-isi-wrapper" class="section isi-section" data-test="isi"> 1299 1300 <div class="isi isi-block"> 1301 <div class="isi-inline-title-wrap"><span class="isi-block-title">ISI Block Title 1302</span></div> 1303 1304 <div class="isi-inline-inner-wrap"><div class="isi-content-block"><h3>IMPORTANT SAFETY INFORMATION and INDICATION for JYNARQUE<sup>®</sup> (tolvaptan)</h3><ul class="list-style-dash"><li><strong>Serious liver problems.</strong> JYNARQUE can cause serious liver problems that can lead to the need for a liver transplant or can lead to death. Stop taking JYNARQUE and call your healthcare provider right away if you get any of the following symptoms:<ul><li>feeling tired</li><li>loss of appetite</li><li>nausea</li><li>right upper stomach (abdomen) pain or tenderness</li><li>vomiting</li><li>fever</li><li>rash</li><li>itching</li><li>yellowing of the skin and white part of the eye (jaundice)</li><li>dark urine</li></ul></li></ul><p><strong>It is important that you have a blood test before you start JYNARQUE to help reduce your risk of liver problems. Your healthcare provider will do a blood test to check your liver:</strong></p><ul><li><strong>before you start taking JYNARQUE</strong></li><li><strong>at 2 weeks and 4 weeks after you start treatment with JYNARQUE</strong></li><li><strong>then monthly for 18 months during treatment with JYNARQUE</strong></li><li><strong>and every 3 months from then on</strong></li></ul><p><strong>Because of the risk of serious liver problems, JYNARQUE is only available through a restricted distribution program called the Tolvaptan for ADPKD Shared System Risk Evaluation and Mitigation Strategy (REMS).</strong></p><p><strong>Do not take JYNARQUE if you:</strong></p><ul><li>have a history of liver problems or have signs or symptoms of liver problems, excluding polycystic liver disease</li><li>cannot feel if you are thirsty or cannot replace fluids by drinking</li><li>have been told that the amount of sodium (salt) in your blood is too high or too low</li><li>are dehydrated</li><li>are allergic to tolvaptan or any of the ingredients in JYNARQUE</li><li>are unable to urinate</li></ul><p><strong>Tell your healthcare provider about all your medical conditions, including if you:</strong></p><ul><li>have a history of sodium (salt) levels that are too low</li><li>are pregnant or plan to become pregnant. It is not known if tolvaptan will harm your unborn baby. Tell your healthcare provider if you become pregnant or think that you may be pregnant</li><li>are breastfeeding or plan to breastfeed. It is not known if tolvaptan passes into your breast milk. Do not breastfeed during your treatment with JYNARQUE. Talk to your healthcare provider about the best way to feed your baby during this time</li></ul><p><strong>Tell your healthcare provider about all the medicines you take,</strong> including prescription medicines, over-the-counter medicines, vitamins, and herbal supplements.</p><ul><li>Taking JYNARQUE with certain medicines could cause you to have too much tolvaptan in your blood. JYNARQUE should not be taken with certain medications. Your healthcare provider can tell you if it is safe to take JYNARQUE with other medicines</li><li>Do not start taking a new medicine without talking to your healthcare provider</li></ul><p><strong>JYNARQUE may cause serious side effects, including:</strong></p><ul><li><strong>Too much sodium in your blood (hypernatremia) and loss of too much body fluid (dehydration).</strong> In some cases, dehydration can lead to extreme loss of body fluid called hypovolemia. You should drink
1304water when you are thirsty and throughout the day and night. Stop taking JYNARQUE and call your healthcare provider if you cannot drink enough water for any reason, such as not having access to water, or vomiting or diarrhea. Tell your healthcare provider if you get any of the following symptoms:<ul><li>dizziness</li><li>fainting</li><li>weight loss</li><li>a change in the way your heart beats</li><li>feeling confused or weak</li></ul></li></ul><p><strong>What should you avoid while taking JYNARQUE?</strong></p><p>Do not drink grapefruit juice during treatment with JYNARQUE. This could cause you to have too much tolvaptan in your blood.</p><p>The <strong>most common side effects</strong> of JYNARQUE are:</p><ul><li>thirst and increased fluid intake</li><li>making large amounts of urine, urinating often, and urinating at night</li></ul><p>These are not all the possible side effects of JYNARQUE. Talk to your healthcare provider about any side effect that bothers you or that does not go away. For more information, ask your healthcare provider or pharmacist.</p><p><strong>If you have any questions about your health or medicines, talk to your healthcare professional.</strong></p><p>To report SUSPECTED ADVERSE REACTIONS, contact Otsuka America Pharmaceutical, Inc. at 1â800â438-9927 or FDA at 1-800-FDA-1088 (<a href="https://www.fda.gov/safety/medwatch-fda-safety-information-and-adverse-event-reporting-program">www.fda.gov/medwatch</a>).</p></div><div class="isi-content-block"><h3>INDICATION:</h3><p><strong>What is JYNARQUE?</strong></p><p>JYNARQUE is a prescription medicine used to slow kidney function decline in adults who are at risk for rapidly progressing autosomal dominant polycystic kidney disease (ADPKD). It is not known if JYNARQUE is safe and effective in children.</p></div><p>Please read <a class="external-link-popup-disabled" href="https://www.otsuka-us.com/media/static/JYNARQUE-PI.pdf" aria-label="FULL PRESCRIBING INFORMATION, Download PDF">FULL PRESCRIBING INFORMATION</a>, including <strong>BOXED WARNING</strong>, and <a class="external-link-popup-disabled" href="https://www.otsuka-us.com/media/static/JYNARQUE-Medguide.pdf" aria-label="MEDICATION GUIDE, Download PDF">MEDICATION GUIDE</a>.</p> 1305</div> 1306 </div> 1307 1308 </section> 1309 1310 </div> 1311 1312 </div> 1313 </div> 1314 </main> 1315 1316 </div> 1317 1318 1319<footer id="section-footer" role="contentinfo"> 1320 <div id="footer"> 1321 <div class="container"> 1322 <div class="row"> 1323 <div class="col-12 col-lg-7 col-xl-8"> 1324 <div class="logo-footer"> 1325 <a href="https://www.otsuka-us.com/" target="_blank" data-test='navbar-branding' data-analytics-name="Otsuka Logo"> 1326 <img src="sites/g/files/qhldwo12166/themes/site/themes/custom/jynarque_hcc_2021/assets/build/img/otsuka-logo.png" alt="Otsuka, Logo"> 1327 </a> 1328 </div> 1329 <div class="footer-inline-items"> <div class="region region-footer-1 clearfix"> 1330 <div id="block-otsukacopyright" class="block block-otsuka-prc-code block-otsuka-copyright"> 1331 1332 1333 <div class="content" data-test='copyright'> 1334 © 2026 Otsuka America Pharmaceutical, Inc. 1335 </div> 1336 </div> 1337<div id="block-footerinlinetext" class="block-content-footer-inline-text block-content-basic block block-block-content block-block-content7f8acdb7-b4f7-4e3a-b947-0371f92fc130 block-footer-inline-text"> 1338 1339 1340 <div class="content"> 1341 1342 1343 1344 1345 1346 1347 <div class="field field--name-body field--type-text-with-summary field--label-hidden"> 1348 <div class="field--item"><p>All rights reserved.</p></div> 1349 </div> 1350 1351 1352 </div> 1353 </div> 1354<div id="block-jynarque-hcc-2021-prcdate" class="block block-otsuka-prc-code block-prc-code-date"> 1355 1356 1357 <div class="content" data-test='prc-date'> 1358 May 2026 1359 </div> 1360 </div> 1361<div id="block-jynarque-hcc-2021-prccode" class="block block-otsuka-prc-code block-prc-code"> 1362 1363 1364 <div class="content" data-test='prc-code'> 1365 10US26EBC0002 1366 </div> 1367 </div> 1368 1369 </div> 1370</div> 1371 </div> 1372 <div class="col-12 col-lg-5 col-xl-4"> 1373 <div class="region region-footer-2 clearfix"> 1374 <nav role="navigation" aria-labelledby="block-jynarque-hcc-2021-footer-menu" id="block-jynarque-hcc-2021-footer"> 1375 1376 <h2 class="visually-hidden" id="block-jynarque-hcc-2021-footer-menu">Footer menu</h2> 1377 1378 1379 1380 <ul data-block="block-jynarque-hcc-2021-footer" data-test="footer-menu" class="menu menu-footer nav"> 1381 <li class="menu-item menu-item-1 nav-item">
1382 <a href="https://www.otsuka-us.com/oapi-privacy-policy" target="_blank">Privacy Policy</a> 1383 </li> 1384 <li class="menu-item menu-item-2 nav-item"> 1385 <a href="https://www.otsuka-us.com/terms-and-conditions" target="_blank">Terms of Use</a> 1386 </li> 1387 <li class="menu-item menu-item-3 nav-item"> 1388 <a href="site-map.html" data-drupal-link-system-path="sitemap">Site Map</a> 1389 </li> 1390 </ul> 1391 1392 1393 1394 </nav> 1395<nav role="navigation" aria-labelledby="block-jynarque-hcc-2021-footerlogos-menu" id="block-jynarque-hcc-2021-footerlogos"> 1396 1397 <h2 class="visually-hidden" id="block-jynarque-hcc-2021-footerlogos-menu">footer logos</h2> 1398 1399 1400 1401 <ul data-block="block-jynarque-hcc-2021-footerlogos" data-test="social-menu" class="menu menu-footer-logos nav"> 1402 <li class="menu-item menu-item-1 nav-item"> 1403 <a href="https://www.facebook.com/JYNARQUE" target="_blank" class="facebook">Facebook</a> 1404 </li> 1405 <li class="menu-item menu-item-2 nav-item"> 1406 <a href="https://www.instagram.com/jynarque_tolvaptan/" target="_blank" class="instagram">Instagram</a> 1407 </li> 1408 <li class="menu-item menu-item-3 nav-item"> 1409 <a href="https://x.com/JYNARQUE" class="twitter" target="_blank">X</a> 1410 </li> 1411 </ul> 1412 1413 1414 1415 </nav> 1416 1417 </div> 1418 1419 </div> 1420 </div> 1421 </div> 1422 </div> 1423 </footer> 1424 1425 1426 <div class="region region-visually-hidden clearfix"> 1427 <div id="block-covidpopupblock" class="block-content-covid-popup-block block-content-basic block block-block-content block-block-content70c8b744-13e7-4ccb-b65f-37b04443e87e block-covid-popup-block"> 1428 1429 1430 <div class="content"> 1431 1432 1433 1434 1435 1436 1437 <div class="field field--name-body field--type-text-with-summary field--label-hidden"> 1438 <div class="field--item"><h2>COVID-19 UPDATE</h2> 1439 1440<p>With the COVID-19 situation constantly developing, your health is our top priority. We hope that you and your families are staying safe and healthy during this unprecedented time.</p> 1441 1442<p>If you are currently taking JYNARQUE<sup>®</sup> (tolvaptan), we encourage you to stay in close contact with your healthcare professional team regarding regular appointments and treatment management plans.</p> 1443 1444<p>At this time, there is no expected impact on medication supply.</p> 1445 1446<p>During the current COVID-19 <span class="text-nowrap">pandemic, the JYNARQUE<sup>®</sup> (tolvaptan)</span> REMS Program requirements remain in effect, as the health of patients who use this product is our top priority. Ongoing blood monitoring required by the REMS Program is extremely important due to the potential risk of serious liver injury from treatment with JYNARQUE. For these lab requirements during COVID-19 pandemic, we are able to temporarily offer our Mobile Phlebotomy Collection Service at no-cost for all patients taking JYNARQUE who prefer to have the REMS required blood work collected at home.</p> 1447 1448<p>In helping patients who have lost a job or health insurance coverage due to the COVID-19 pandemic and to get through these challenging times, we have extended our Patient Support Program to provide âno-costâ access for patients in the U.S. who are taking JYNARQUE. Please call Otsuka Patient Support at <a class="cta_phone" href="tel:1-855-242-7787">1-855-242-7787</a> for more information on both programs.</p> 1449 1450<p>For help accessing JYNARQUE, go to <a class="cta_exit" href="https://www.otsukapatientsupport.com/jynarque" target="_blank">www.otsukapatientsupport.com/jynarque</a> or call Otsuka Patient Support at <a class="cta_phone" href="tel:1-855-242-7787">1-855-242-7787</a>. The nurses at Otsuka Patient Support can answer questions related to Product Accessibility, Reimbursement and connecting patients to local treatment sites in their community.</p> 1451 1452<p>Please read <a class="dummy external-link-popup-disabled" href="https://www.otsuka-u
1452s.com/media/static/JYNARQUE-PI.pdf" target="_blank">FULL PRESCRIBING INFORMATION</a>, including <strong>BOXED WARNING</strong>, and <a class="dummy external-link-popup-disabled" href="https://www.otsuka-us.com/media/static/JYNARQUE-Medguide.pdf" target="_blank">MEDICATION GUIDE</a>.</p> 1453 1454<p class="covid-footnote"><span class="covid-prc-1">September 2020</span><span class="covid-prc-2">10US20EBC0103</span></p> 1455</div> 1456 </div> 1457 1458 1459 </div> 1460 </div> 1461 1462 </div> 1463 1464 1465 </div> 1466 1467 1468 1469 1470 1471 1472 1473 1474 1475<section id="drawer-isi" class="isi-tray jsIsiContainer isi-drawer-collapsed" aria-label="ISI"> 1476 1477 <!--<div id="isi-drawer-wrapper" class="isi-drawer-collapsed">--> 1478 1479 <div class="isi-header"> 1480 <div class="isi-header-wrap"> 1481 <div class="drawer-title">IMPORTANT SAFETY INFORMATION and INDICATION for JYNARQUE<sup>®</sup> (tolvaptan) 1482</div> 1483 <button class="isi-btn jsIsiMinimize" data-oapigtmcategory="Button Clicks" data-oapigtmaction="ISI" data-oapigtmlabel="More +"><span class="jsSwapText jsSwapTextExpand">More +</span><span class="jsSwapText jsSwapTextCollapse hide">Less -</span><span class="isi-btn-icon"></span></button> 1484 </div> 1485 </div> 1486 1487 <div class="isi isi-block isi-drawer-content isi-content-wrap"> 1488 <div class="jcf-scrollable jcf-container mCustomScrollbar"> 1489 <div class="isi-drawer-content-heading">ISI Block Title 1490</div> 1491 <div class="isi-content-block"><h3>IMPORTANT SAFETY INFORMATION and INDICATION for JYNARQUE<sup>®</sup> (tolvaptan)</h3><ul class="list-style-dash"><li><strong>Serious liver problems.</strong> JYNARQUE can cause serious liver problems that can lead to the need for a liver transplant or can lead to death. Stop taking JYNARQUE and call your healthcare provider right away if you get any of the following symptoms:<ul><li>feeling tired</li><li>loss of appetite</li><li>nausea</li><li>right upper stomach (abdomen) pain or tenderness</li><li>vomiting</li><li>fever</li><li>rash</li><li>itching</li><li>yellowing of the skin and white part of the eye (jaundice)</li><li>dark urine</li></ul></li></ul><p><strong>It is important that you have a blood test before you start JYNARQUE to help reduce your risk of liver problems. Your healthcare provider will do a blood test to check your liver:</strong></p><ul><li><strong>before you start taking JYNARQUE</strong></li><li><strong>at 2 weeks and 4 weeks after you start treatment with JYNARQUE</strong></li><li><strong>then monthly for 18 months during treatment with JYNARQUE</strong></li><li><strong>and every 3 months from then on</strong></li></ul><p><strong>Because of the risk of serious liver problems, JYNARQUE is only available through a restricted distribution program called the Tolvaptan for ADPKD Shared System Risk Evaluation and Mitigation Strategy (REMS).</strong></p><p><strong>Do not take JYNARQUE if you:</strong></p><ul><li>have a history of liver problems or have signs or symptoms of liver problems, excluding polycystic liver disease</li><li>cannot feel if you are thirsty or cannot replace fluids by drinking</li><li>have been told that the amount of sodium (salt) in your blood is too high or too low</li><li>are dehydrated</li><li>are allergic to tolvaptan or any of the ingredients in JYNARQUE</li><li>are unable to urinate</li></ul><p><strong>Tell your healthcare provider about all your medical conditions, including if you:</strong></p><ul><li>have a history of sodium (salt) levels that are too low</li><li>are pregnant or plan to become pregnant. It is not known if tolvaptan will harm your unborn baby. Tell your healthcare provider if you become pregnant or think that you may be pregnant</li><li>are breastfeeding or plan to breastfeed. It is not known if tolvaptan passes into your breast milk. Do not breastfeed during your treatment with JYNARQUE. Talk to your healthcare provider about the best way to feed your baby during this time</li></ul><p><strong>Tell your healthcare provider about all the medicines you take,</strong> including prescription medicines, over-the-counter medicines, vitamins, and herbal supplements.</p><ul><li>Taking JYNARQUE with certain medicines could cause you to have too much tolvaptan in your blood. JYNARQUE should not be taken with certain medications. Your healthcare provider can tell you if it is safe to take JYNARQUE with other medicines</li><li>Do not start taking a new medicine without talking to your healthcare provider</li></ul><p><strong>JYNARQUE may cause serious side effects, including:</strong></p><ul><li><strong>Too much sodium in your blood (hypernatremia) and loss of too much body fluid (dehydration).</strong> In some cases, dehydration can lead to extreme loss of body fluid called hypovolemia. You should drink
1491water when you are thirsty and throughout the day and night. Stop taking JYNARQUE and call your healthcare provider if you cannot drink enough water for any reason, such as not having access to water, or vomiting or diarrhea. Tell your healthcare provider if you get any of the following symptoms:<ul><li>dizziness</li><li>fainting</li><li>weight loss</li><li>a change in the way your heart beats</li><li>feeling confused or weak</li></ul></li></ul><p><strong>What should you avoid while taking JYNARQUE?</strong></p><p>Do not drink grapefruit juice during treatment with JYNARQUE. This could cause you to have too much tolvaptan in your blood.</p><p>The <strong>most common side effects</strong> of JYNARQUE are:</p><ul><li>thirst and increased fluid intake</li><li>making large amounts of urine, urinating often, and urinating at night</li></ul><p>These are not all the possible side effects of JYNARQUE. Talk to your healthcare provider about any side effect that bothers you or that does not go away. For more information, ask your healthcare provider or pharmacist.</p><p><strong>If you have any questions about your health or medicines, talk to your healthcare professional.</strong></p><p>To report SUSPECTED ADVERSE REACTIONS, contact Otsuka America Pharmaceutical, Inc. at 1â800â438-9927 or FDA at 1-800-FDA-1088 (<a href="https://www.fda.gov/safety/medwatch-fda-safety-information-and-adverse-event-reporting-program">www.fda.gov/medwatch</a>).</p></div><div class="isi-content-block"><h3>INDICATION:</h3><p><strong>What is JYNARQUE?</strong></p><p>JYNARQUE is a prescription medicine used to slow kidney function decline in adults who are at risk for rapidly progressing autosomal dominant polycystic kidney disease (ADPKD). It is not known if JYNARQUE is safe and effective in children.</p></div><p>Please read <a class="external-link-popup-disabled" href="https://www.otsuka-us.com/media/static/JYNARQUE-PI.pdf" aria-label="FULL PRESCRIBING INFORMATION, Download PDF">FULL PRESCRIBING INFORMATION</a>, including <strong>BOXED WARNING</strong>, and <a class="external-link-popup-disabled" href="https://www.otsuka-us.com/media/static/JYNARQUE-Medguide.pdf" aria-label="MEDICATION GUIDE, Download PDF">MEDICATION GUIDE</a>.</p> 1492 1493 </div> 1494 </div> 1495 1496 <!--</div>--><!--/#isi-drawer-wrapper--> 1497 1498</section> 1499<style> 1500 1501 .isi-tray { 1502 left: 0%; 1503 width: 100%; 1504 } 1505 .isi-drawer-expanded { 1506 height: 100px; 1507 } 1508 .isi-drawer-collapsed { 1509 height: 40px; 1510 } 1511 1512 .isi-tray.isi-drawer-expanded .isi-content-wrap, 1513 .isi-tray.isi-drawer-expanded .isi-content-wrap>div { 1514 height: calc(50vh - 220px); 1515 } 1516 @media all and (min-width: 768px) { 1517 .isi-tray.isi-drawer-expanded .isi-content-wrap, 1518 .isi-tray.isi-drawer-expanded .isi-content-wrap>div { 1519 height: calc(50vh - 60px); 1520 } 1521 } 1522</style> 1523 1524 1525
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