https://lazarjov.com/_next/static/chunks/pages/publications/brain-…-electrical-stimulation-2b8393f417fdfcb0.js

1(self.webpackChunk_N_E=self.webpackChunk_N_E||[]).push([[469],{3411:(e,n,i)=>{(window.__NEXT_P=window.__NEXT_P||[]).push(["/publications/brain-computer-interface-triggered-functional-electrical-stimulation",function(){return i(9018)}])},9018:(e,n,i)=>{"use strict";i.r(n),i.d(n,{default:()=>c,meta:()=>r});var t=i(4848),s=i(8453),a=i(3399);let r={title:"Brain-computer interface-triggered functional electrical stimulation therapy rehabilitation of reaching and grasping after spinal cord injury: A feasibility study",authors:["Lazar I. Jovanovic","Naaz Kapadia","Zivanovic Vera","Hope Jervis Rademeyer","Mohammad Alavinia","Colleen McGillivray","Sukhvinder Kalsi-Ryan","Milos R. Popovic","Cesar Marquez-Chin"],journal:"Spinal Cord Series and Cases",volume:"",issue:"",pages:"",datePublished:"2021-03-19",doi:"10.1038/s41394-020-00380-4"},l=e=>(0,t.jsx)(a.X,Object.assign({meta:r},e));function o(e){let n=Object.assign({h1:"h1",strong:"strong",p:"p"},(0,s.RP)(),e.components);return(0,t.jsxs)(t.Fragment,{children:[(0,t.jsx)(n.h1,{children:(0,t.jsx)(n.strong,{children:"Study design"})}),"\n",(0,t.jsx)(n.p,{children:"Feasibility and preliminary clinical efficacy analysis in a single-arm interventional study."}),"\n",(0,t.jsx)(n.h1,{children:(0,t.jsx)(n.strong,{children:"Objectives"})}),"\n",(0,t.jsx)(n.p,{children:"We developed a brain–computer interface-triggered functional electrical stimulation therapy (BCI-FEST) system for clinical application and conducted an interventional study to (1) assess its feasibility and (2) understand its potential\nclinical efficacy for the rehabilitation of reaching and grasping in individuals with sub-acute spinal cord injury (SCI)."}),"\n",(0,t.jsx)(n.h1,{children:(0,t.jsx)(n.strong,{children:"Setting"})}),"\n",(0,t.jsx)(n.p,{children:"Spinal cord injury rehabilitation hospital—Toronto Rehabilitation Institute—Lyndhurst Centre."}),"\n",(0,t.jsx)(n.h1,{children:(0,t.jsx)(n.strong,{children:"Methods"})}),"\n",(0,t.jsx)(n.p,{children:"Five participants with sub-acute SCI completed between 12 and 40 1-hour sessions using BCI-FEST, with up to 5 sessions a week. We assessed feasibility by measuring participants’ compliance with treatment, the occurrence of adverse events, BCI sensitivity, and BCI setup duration. Clinical efficacy was assessed using Functional Independence Measure (FIM) and Spinal Cord Independence Measure (SCIM), as primary outcomes. In addition, we used two upper-limb function tests as secondary outcomes."}),"\n",(0,t.jsx)(n.h1,{children:(0,t.jsx)(n.strong,{children:"Results"})}),"\n",(0,t.jsx)(n.p,{children:"On average, participants completed 29.8 sessions with no adverse events. Only one of the 149 sessions was affected by technical challenges. The BCI sensitivity ranged between 69.5 and 80.2%, and the mean BCI setup duration was ~11 min. In the primary outcomes, three out of five participants showed changes greater than the minimal clinically important differences (MCIDs). Additionally, the mean change in secondary outcome measures met the threshold for detecting MCID as well; four out of five participants achieved MCID."}),"\n",(0,t.jsx)(n.h1,{children:(0,t.jsx)(n.strong,{children:"Conclusions"})}),"\n",(0,t.jsx)(n.p,{children:"The new BCI-FEST intervention is safe, feasible, and promising for the rehabilitation of reaching and grasping after SCI."})]})}let c=function(e={}){return(0,t.jsx)(l,Object.assign({},e,{children:(0,t.jsx)(o,e)}))}},1298:(e,n,i)=>{"use strict";i.d(n,{s:()=>a});var t=i(4848),s=i(53);function a({children:e,className:n}){return(0,t.jsx)("div",{className:(0,s.A)(n,"prose dark:prose-invert"),children:e})}},3399:(e,n,i)=>{"use strict";i.d(n,{X:()=>u});var t=i(4848),s=i(3368),a=i.n(s),r=i(6715),l=i(2210),o=i(7753),c=i(1298),d=i(3175);function h(e){return(0,t.jsx)("svg",{viewBox:"0 0 16 16",fill:"none","aria-hidden":"true",...e,children:(0,t.jsx)("path",{d:"M7.25 11.25 3.75 8m0 0 3.5-3.25M3.75 8h8.5",strokeWidth:"1.5",strokeLinecap:"round",strokeLinejoin:"round"})})}function u({children:e,meta:n,isRssFeed:i=!1,previousPathname:s}){let u=(0,r.useRouter)();return i?e:(0,t.jsx)(t.Fragment,{children:(0,t.jsxs)(d.O,{children:[(0,t.jsxs)(a(),{children:[(0,t.jsx)("title",{children:`${n.title}`}),(0,t.jsx)("meta",{name:"description",content:n.description})]}),(0,t.jsx)(l.m,{className:"mt-16 lg:mt-32",children:(0,t.jsx)("div",{className:"xl:relative",children:(0,t.jsxs)("div",{className:"mx-auto max-w-2xl",children:[s&&(0,t.jsx)("button",{type:"button",onClick:()=>u.back(),"aria-label":"Go back to articles",className:"group mb-8 flex h-10 w-10 items-center justify-center rounded-full bg-white shadow-md shadow-zinc-800/5 ring-1 ring-zinc-900/5 transition dark:border dark:border-zinc-700/50 dark:bg-zinc-800 dark:ring-0 dark:ring-white/10 dark:hover:border-zinc-700 dark:hover:ring-white/20 lg:absolute lg:-left-5 lg:mb-0 lg:-mt-2 xl:-top-1.5 xl:left-0 xl:mt-0",children:(0,t.jsx)(h,{className:"h-4 w-4 stroke-zinc-500 transition group-hover:stroke-zinc-700 dark:stroke-zinc-500 dark:group-hover:stroke-zinc-400"})}),(0,t.jsxs)("article",{children:[(0,t.jsxs)("header",{className:"flex flex-col",children:[(0,t.jsx)("h1",{className:"mt-6 text-4xl font-bold text-zinc-800 dark:text-zinc-100",children:n.title}),(0,t.jsxs)("time",{dateTime:n.datePublished,className:"order-first flex items-center text-base text-zinc-400 dark:text-zinc-500",children:[(0,t.jsx)("span",{className:"h-4 w-0.5 rounded-full bg-zinc-200 dark:bg-zinc-500"}),(0,t.jsx)("span",{className:"ml-3",children:(0,o.Y)(n.datePublished)})]})]}),(0,t.jsx)(c.s,{className:"mt-8",children:e}),(0,t.jsx)("a",{href:`https://doi.org/${n.doi}`,target:"_blank",rel:"noopener noreferrer",children:(0,t.jsx)("span",{className:"font-semibold text-blue-500 underline decoration-blue-500/20 hover:text-blue-600 hover:decoration-blue-500 dark:text-blue-400 dark:decoration-blue-400/30 dark:hover:decoration-blue-400",children:"Read the full article."})})]})]})})})]})})}},7753:(e,n,i)=>{"use strict";function t(e){return new Date(`${e}T00:00:00Z`).toLocaleDateString("en-US",{day:"numeric",month:"long",year:"numeric",timeZone:"UTC"})}i.d(n,{Y:()=>t})},8453:(e,n,i)=>{"use strict";i.d(n,{RP:()=>a});var t=i(6540);let s=t.createContext({});function a(e){let n=t.useContext(s);return t.useMemo(()=>"function"==typeof e?e(n):{...n,...e},[n,e])}}},e=>{var n=n=>e(e.s=n);e.O(0,[275,965,304,175,636,593,792],()=>n(3411)),_N_E=e.O()}]);