https://cancentus.com/assets/Aidd-B0p-Pcat.js

1import{r as p}from"./rolldown-runtime-CXHxssQy.js";import{i as f,t as y}from"./react-vendor-DfDPcXOr.js";import{c as v,l as m,s as w}from"./index-ZJecFVAl.js";var i=p(f(),1),e=y(),j=["Import your protein target sequence, optionally a 3D structure.","For selectivity-led designs, add sequences for the related proteins you care about.","Upload the compound set you want screened - typically tens to a few thousand candidates.","Execute the run in the Cancentus portal and follow progress end to end.","Download and review full results directly in the portal.","You keep all results and IP - Cancentus does not retain rights.","If you choose to share experimental readouts, Cancentus can retrain the general model for better predictions."],b=["Share your protein target sequence, optionally a 3D structure.","Provide the compound library to screen - typically on the order of 100k–250k compounds.","Cancentus executes the full in-silico screening run for you.","Receive the complete results package: predicted affinities and 3D models for every compound.","You own all outputs and IP - Cancentus retains no rights to your results."],N=5e3,l=[{text:"Full, interactive 3D Models (ribbon or atomic) can be viewed and downloaded in different formats, all in the browser.",rect:{left:37,top:20.75,width:36.5,height:49.75}},{text:"Targets and compounds are co-folded, and visible in the 3D viewer.",rect:{left:1.5,top:20.75,width:72,height:49.75}},{text:"Two affinity scores are calculated with each run.",rect:{left:1,top:70,width:62,height:28}},{text:"Ranking of active compounds allows your team to compare results and define candidates easily.",rect:{left:74,top:10,width:26,height:84}}];function k(){const[t,o]=(0,i.useState)(0),[x,h]=(0,i.useState)(0),[r,u]=(0,i.useState)(()=>typeof window<"u"?window.matchMedia("(prefers-reduced-motion: reduce)").matches:!1);(0,i.useEffect)(()=>{const s=window.matchMedia("(prefers-reduced-motion: reduce)"),a=()=>u(s.matches);return s.addEventListener("change",a),()=>s.removeEventListener("change",a)},[]),(0,i.useEffect)(()=>{if(r)return;const s=window.setInterval(()=>{o(a=>(a+1)%l.length)},N);return()=>window.clearInterval(s)},[r,x]);const g=s=>{o(s),h(a=>a+1)},d=l[t],n=d.rect;return(0,e.jsx)("div",{className:"py-32 px-6 lg:px-8",children:(0,e.jsxs)("div",{className:"mx-auto max-w-2xl lg:max-w-7xl",children:[(0,e.jsx)("p",{className:"font-mono text-xs/5 font-semibold tracking-widest text-gray-500 uppercase",children:"Smarca2 Example"}),(0,e.jsx)("h2",{className:"mt-2 max-w-3xl text-4xl font-medium tracking-tight text-pretty text-gray-950 sm:text-6xl",style:{fontFamily:"Switzer, system-ui, sans-serif"},children:"All your data in one place"}),(0,e.jsxs)("div",{className:"mt-16 relative",children:[(0,e.jsx)("div",{className:"absolute -inset-1 rounded-[calc(var(--radius-2xl)+var(--spacing))] shadow-sm ring-1 ring-black/5"}),(0,e.jsxs)("div",{className:"relative rounded-2xl shadow-2xl ring-1 ring-black/10 overflow-hidden bg-gray-100",children:[(0,e.jsx)("img",{src:"/smarca2_example.png",alt:"ABI Leaderboard for Smarca2: 2D ligand, 3D protein–ligand view, and ranked results",className:"w-full",decoding:"async"}),!r&&(0,e.jsx)("div",{className:"absolute inset-0 pointer-events-none","aria-hidden":!0,children:(0,e.jsx)("div",{className:"absolute rounded-md border-2 border-white/95 shadow-[0_0_0_9999px_rgba(15,23,42,0.52)] transition-[left,top,width,height] duration-700 ease-in-out",style:{left:`${n.left}%`,top:`${n.top}%`,width:`${n.width}%`,height:`${n.height}%`}})})]})]}),(0,e.jsx)("div",{className:"mt-8 mx-auto max-w-3xl text-center","aria-live":r?void 0:"polite",children:r?(0,e.jsx)("ol",{className:"list-inside list-decimal space-y-3 text-base sm:text-lg text-gray-600 marker:text-gray-400",children:l.map(s=>(0,e.jsx)("li",{children:s.text},s.text))}):(0,e.jsxs)(e.Fragment,{children:[(0,e.jsx)("p",{className:"min-h-[3rem] sm:min-h-[3.5rem] text-base sm:text-lg font-normal text-pretty text-gray-600 motion-safe:animate-in motion-safe:fade-in motion-safe:duration-300 motion-safe:slide-in-from-bottom-1",children:d.text},t),(0,e.jsx)("div",{className:"mt-5 flex flex-wrap items-center justify-center gap-3",role:"tablist","aria-label":"Example highlights",children:l.map((s,a)=>{const c=a===t;return(0,e.jsx)("button",{type:"button",role:"tab","aria-selected":c,tabIndex:0,onClick:()=>g(a),className:`size-2.5 rounded-full transition-[transform,background-color] duration-200 ${c?"scale-125 bg-gray-500":"bg-gray-300 hover:bg-gray-400"}`,children:(0,e.jsxs)("span",{className:"sr-only",children:["Highlight ",a+1," of ",l.length]})},a)})})]})})]})})}function S(){return(0,e.jsx)("div",{className:"mt-10 sm:mt-16",children:(0,e.jsx)("img",{src:"/aidd_loop.svg",alt:"Analysis loop: customer setup, AIDD in-silico run, compound synthesis, repeat",className:"w-full h-auto",decoding:"async"})})}function A(){return(0,i.useEffect)(()=>{const t=document.createElement("link");return t.rel="stylesheet",t.href="https://api.fontshare.com/v2/css?f[]=switzer@400,500,600,700&display=swap",document.head.appendChild(t),()=>{document.head.removeChild(t)}},[]),(0,e.jsxs)("div",{className:"text-gray-950 antialiased",style:{fontFamily:"Switzer, system-ui, sans-serif",background:"white"},children:[(0,e.jsx)("div",{className:"overflow-hidden",children:(0,e.jsxs)("div",{className:"relative",children:[(0,e.jsx)("div",{className:"pointer-events-none absolute inset-0",style:{background:"linear-gradient(145deg, #fff1be 28%, #ee87cb 70%, #b060ff 100%)"}}),(0,e.jsx)("div",{className:"relative px-6 lg:px-8",children:(0,e.jsxs)("div",{className:"mx-auto max-w-2xl lg:max-w-7xl",children:[(0,e.jsx)(v,{homeHref:"/"}

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1export{A as default};