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20<meta name="description" content="Enrolling in the THIOLA Total Care Hub ensures comprehensive personalized support to help people with cystinuria and physicians easily access and manage treatment" />
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77            <div class="field field--name-body field--type-text-with-summary field--label-hidden field--item"><ul class="menu nav navbar-nav navbar-transparent"><li><a data-scroll="" gtm-data-action="click" gtm-data-category="header" gtm-data-label="view-safety-information" href="#block-isi" id="header-isi"><span class="hidden-xs">See Important </span>Safety Information<span class="hidden-xs"> below</span></a></li>
78	<li><a gtm-data-action="download" gtm-data-category="header" gtm-data-label="thiola-ec-pi" href="/sites/default/files/pdfs/nda/ThiolaEC_PI.pdf" id="header-pi" target="_blank">THIOLA EC Prescribing Information</a></li>
79	<li><a gtm-data-action="download" gtm-data-category="header" gtm-data-label="thiola-pi" href="/sites/default/files/pdfs/nda/Thiola_PI.pdf" id="header-pi" target="_blank">THIOLA Prescribing Information</a></li>
80	<li><a class="hcp-modal-toggle" gtm-data-action="click" gtm-data-category="header" gtm-data-label="for-healthcare-professionals-only" href="https://www.THIOLAEChcp.com" id="header-external-thiolahcp-link">For Healthcare Professionals only</a></li>
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127        <a href="/total-care-hub" class="main-nav-total-care-hub is-active" data-drupal-link-system-path="node/5">Total Care HUB</a>
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149      For Healthcare Professionals only
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168                              <h1>THIOLA EC Total Care HUB<sup>®</sup></h1>
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174<h2 style="color: #ffffff !important;font-size:42px;font-weight:bold; padding-bottom:25px;">THIOLA EC: Only available through the<br />
175Total Care HUB</h2>
176
177<p style="color: #ffffff;font-size:23px; padding-bottom:55px;max-width:540px;">Ensure you receive THIOLA EC as prescribed, rather than a generic.</p>
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426
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437<h1>Your goal is stone prevention—<br />
438the TOTAL CARE HUB helps with the rest</h1>
439
440<p>We understand that living with a rare disease like cystinuria can be challenging. That's why the Total Care HUB provides comprehensive support for the community of patients and caregivers facing these daily challenges.</p>
441
442<p>Dedicated to your care, our team offers customized assistance for those taking brand name THIOLA<sup>®</sup> (tiopronin) and THIOLA EC<sup>®</sup> (tiopronin, delayed-release tablets). From insurance coverage to delivery of medication, to lifestyle tips, we can help with many aspects of your treatment journey.</p>
443
444<p>Follow these tips to ensure you receive your prescribed brand name THIOLA EC</p>
445
446<ul>
447	<li>Make sure your doctor includes <strong>Dispense As Written (DAW)</strong> on your THIOLA EC patient enrollment form</li>
448	<li><strong>Call the HUB to confirm</strong> your brand name THIOLA EC prescription</li>
449	<li><strong>Check that your pill bottle says THIOLA EC</strong>, provided by Eversana, our specialty pharmacy</li>
450</ul>
451
452<p>&nbsp;</p>
453
454<p style="font-size: 16px; line-height: 16px;">*The Total Care HUB, administered by Specialty Pharmacy, EVERSANA, is the ONLY patient services and dispensing pharmacy for brand name THIOLA and THIOLA EC.</p>
455
456<p>&nbsp;</p>
457
458<div class="container-fluid max-width-800" style="max-width: 781px;width: 100%;margin: 0 auto;padding: 0;">
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465<p style="margin: 23px 0;text-align: left;">Total Care HUB members can call the HUB 24 hours a day, 7 days a week, at 844-4-THIOLA (844-484-4652).<br />
466If you're not yet a member, talk to your doctor about a prescription.</p>
467</div>
468
469<div class="col-xs-12 col-sm-12 col-md-2 col-lg-2"><img alt="Call" data-entity-type="file" data-entity-uuid="0e342733-6599-4c94-9bfe-12e1bce80222" src="/sites/default/files/inline-images/icon-call.png" /></div>
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475</div>
476</div>
477
478<div id="nurse-video" style="display: block; position: relative;top: -50px;visibility: hidden;">&nbsp;</div>
479
480<h1><span style="color: #5bcf57">Hear</span> how the Total Care HUB works</h1>
481
482<p>Hear one of the clinical nurse coordinators explain how members of the team work together to provide support and assistance in the THIOLA EC Total Care HUB.</p>
483
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485
486<p>
487<video controls="" data-title="Myhub nurse video" gtm-data-action="navigate" gtm-data-category="video-total-care-hub" gtm-data-label="watch-myhub-nurse-video" height="440" id="nurse-video" onended="sendEvent('Ended', this)" onpause="sendEvent('Pause', this)" onplay="sendEvent('Play', this)" poster="/sites/default/files/inline-images/video-bg_0.jpg" preload="metadata"><source src="/video/hub-molly-v2.1.mp4" type="video/mp4" /> <source src="/video/hub-molly-v2.1.mp4" type="video/ogg" /> Your browser does not support HTML video.</video>
488</p>
489
490<p>&nbsp;</p>
491
492<p>&nbsp;</p>
493
494<h1>Meet the team</h1>
495
496<p>You are supported by a dedicated team of professionals working hand-in-hand to help you manage this disorder.</p>
497
498<div class="mobile-view-area">
499<p>&nbsp;</p>
500<img alt="Hub Team" data-align="center" data-entity-type="file" data-entity-uuid="6d5d5178-6c7c-47c5-abe8-5ba48c1e16f0" src="/sites/default/files/inline-images/molly-bg-mob.png" /></div>
501
502<div class="desktop-view-area">
503<p>&nbsp;</p>
504
505<p><img alt="Meet the myHub team" data-entity-type="file" data-entity-uuid="db32a8eb-6ea6-4aa2-a371-0101189f9372" src="/sites/default/files/inline-images/molly-bg_0.jpg" /></p>
506</div>
507<script type='text/javascript'>
508function sendEvent(action, element) {
509     var videoTitle = element.getAttribute('data-title');
510      if (dataLayer && videoTitle) {
511        dataLayer.push({
512            'event': 'gtm.custom_event',
513            'eventInfo': {
514                'category': 'Video',
515                'action': action,
516                'label': element,
517                'value': 0,
518                'nonInteraction': false
519            }
520        });
521    }
522}
523</script>
523
524          </div>
525        
526        
527        
528        
529        
530        
531        
532        
533        
534                
535                          <div class="container-fluid max-width-800">
536            <div class="access-hub-cta-1">
537              <div class="icon"></div>
538              <div class="icon-bg"></div>
539              <div class="card">
540                <div class="card-body">
541                  <div class="cta-4-body">
542                    <p style="text-align:center;">Getting THIOLA EC<sup>®</sup> (tiopronin) tablets is simple through the Total Care HUB. Download the enrollment form now and talk to your doctor about getting started.</p>
543
544                  </div>
545                </div>
546                                  <div class="card-footer">
547                    <a gtm-data-category=subnav-total-care-hub	gtm-data-action=navigate	gtm-data-label=enrollment-form-myhub class="btn-cta btn btn-lg btn-xl btn-primary" href="/sites/default/files/pdfs/THI460v4_THIOLA_EC_EnrollmentForm_20241210.pdf">Get THIOLA EC</a>
548                  </div>
549                              </div>
550            </div>
551          </div>
552        
553
554
555
556      </section>
557              <section id="prescription-delivery" class="section section-scroll-trigger">
558
559                              <div id="section-3-body" class="car-section body-container container-fluid max-width-800 with-section-icon">
560                              <img class="section-icon" src="/sites/default/files/2020-07/icon-hub_1.png" alt="Clinical Nurse Coordinators Molly and Angela"/>
561                            <h1>Clinical Nurse Coordinators</h1>
562
563<ul>
564	<li>Help you understand your disease.</li>
565	<li>Provide you with tips to help manage your treatment.</li>
566	<li>Communicate with your doctors.</li>
567</ul>
568
569<div class="mobile-view-area">
570<p>&nbsp;</p>
571<img alt="Nurses" data-align="center" data-entity-type="file" data-entity-uuid="3c06bd54-53df-4ce9-a4fc-15eb15bdaddf" src="/sites/default/files/inline-images/MuHub-nurses-mob.png" /></div>
572
573<div class="desktop-view-area">
574<p>&nbsp;</p>
575
576<div class="imager" style="margin-left: -110px;"><img alt="Nurses" data-align="center" data-entity-type="file" data-entity-uuid="a9b34ea4-d231-4be8-8cfd-49f2f65da9fe" src="/sites/default/files/inline-images/MuHub-nurses.png" /></div>
577</div>
578
579<p>&nbsp;</p>
580
581            </div>
582                  
583        
584        
585        
586        
587        
588        
589        
590        
591      </section>
592              <section id="support" class="section  section-scroll-trigger">
593
594        <div id="section-4-body" class="body-container container-fluid max-width-800 with-section-icon">
595                      <img class="section-icon" src="/sites/default/files/2020-07/icon-pharmacist_2.png" alt="Pharmacists"/>
596                    <style type="text/css">#pharmacists {
597background-color: #d8edef;
598padding: 0 0 40px 0;
599}
600</style>
601<h1>Pharmacists</h1>
602
603<ul>
604	<li>Ensure that your prescription is accurately dispensed.</li>
605</ul>
606
607<ul>
608	<li>Answer your questions about your dosing and treatment regimen.</li>
609</ul>
610
611<div class="mobile-view-area">
612<p>&nbsp;</p>
613<img alt="Pharmacists" data-align="center" data-entity-type="file" data-entity-uuid="5749fffc-59f5-4333-a844-d8cd448eb1f5" src="/sites/default/files/inline-images/Pharmacists-Mob2_0.png" /></div>
614
615<div class="desktop-view-area">
616<p>&nbsp;</p>
617
618<div class="imager" style="margin-left: -60px;"><img alt="Pharmacists" data-align="center" data-entity-type="file" data-entity-uuid="f6f12bf3-d05b-49e5-a6b9-60af8a9f7316" src="/sites/default/files/inline-images/Pharmacists-desk3.png" /></div>
619</div>
620
621        </div>
622
623        
624        
625        
626        
627        
628        
629        
630        
631        
632      </section>
633              <section id="educational-communications" class="section  section-scroll-trigger">
634
635                  <div id="section-5-body" class="hat-section body-container container-fluid max-width-800 with-section-icon">
636                          <img class="section-icon" src="/sites/default/files/2020-07/icon-patient_0.png" alt="Patient Service Coordinators"/>
637                        <style type="text/css">#patient-service-coordinators {background-color: #d8edef;}
638</style>
639<h1>Patient Services Coordinators</h1>
640
641<ul>
642	<li>Are your main point of contact.</li>
643</ul>
644
645<ul>
646	<li>Provide live support to keep you on track with your treatment plan.</li>
647</ul>
648
649<ul>
650	<li>Offer information with insurance questions, such as being under-insured or having no insurance.</li>
651</ul>
652
653<ul>
654	<li>Assist with payment issues.</li>
655</ul>
656
657<ul>
658	<li>Provide information on available patient assistance programs.</li>
659</ul>
660
661<ul>
662	<li>Coordinate your monthly prescription refills and send you reminders so you never run out of medication.</li>
663</ul>
664
665<ul>
666	<li>Arrange for delivery of your medication directly to your doorstep – saving you trips to the pharmacy.</li>
667</ul>
668
669<ul>
670	<li>
670Give help with copays for commercial insurance.</li>
671</ul>
672
673<p>&nbsp;</p>
674
675<div class="imager imager-especial-8" style="margin-left: -110px;"><img alt="Copay" data-align="center" data-entity-type="file" data-entity-uuid="d8900866-2122-481e-878d-353c414e7a70" src="/sites/default/files/inline-images/img-copay_1.png" /></div>
676
677<p>&nbsp;</p>
678
679<p style="font-size: 16px;">*Copay Terms and Conditions:</p>
680
681<ul style="margin-bottom: 0;">
682	<li style="font-size: 16px;">Program is valid for patients with commercial or private insurance.</li>
683</ul>
684
685<ul style="margin-bottom: 0;">
686	<li style="font-size: 16px;">Must be a US resident.</li>
687</ul>
688
689<ul style="margin-bottom: 0;">
690	<li style="font-size: 16px;">Not valid for patients insured by a federal or state government-funded health plan, including Medicare, Medicare Advantage, Medicaid, and TRICARE.</li>
691</ul>
692
693<ul style="margin-bottom: 0;">
694	<li style="font-size: 16px;">Void where the program is prohibited by law.</li>
695</ul>
696
697<ul style="margin-bottom: 0;">
698	<li style="font-size: 16px;">Not valid for uninsured patients.</li>
699</ul>
700
701<ul style="margin-bottom: 0;">
702	<li style="font-size: 16px;">Program does not replace prescription drug coverage or insurance and is not intended to substitute for coverage.</li>
703</ul>
704
705<ul style="margin-bottom: 0;">
706	<li style="font-size: 16px;">Travere Therapeutics reserves the right to terminate or modify this program at any time without notice.</li>
707</ul>
708
709<p style="font-size: 16px;">&nbsp;</p>
710
711          </div>
712        
713        
714        
715                  <div class="container-fluid max-width-800">
716            <div style="text-align:center;"><img alt="pattient" data-align="center" data-entity-type="file" data-entity-uuid="4ef3f9dd-4b0e-4a8e-b4ac-e0e908ba3998" src="/sites/default/files/inline-images/pullquote-3.png" /></div>
717
718<p>&nbsp;<br />
719&nbsp;</p>
720
721<div class="title-area-hub" style="display: flex;height: auto;flex-direction: row;
722width: 100%;">
723<p><img alt="myHub" data-align="left" data-entity-type="file" data-entity-uuid="bf112cd9-3305-47bf-819b-445e3dae191a" src="/sites/default/files/inline-images/experience-myhub-example_0.png" /></p>
724</div>
725
726<p>&nbsp;</p>
727
728<p>myHUB is an extension of the THIOLA EC Total Care HUB that is available to patients taking THIOLA EC. Once you're a part of the Total Care HUB, you're automatically a member of myHUB, and will get educational brochures, personalized text message communications, and invitations to webinars and live events. You can choose your preference – calls, texts, or live chats – for communications.</p>
729
730<p>&nbsp;</p>
731
732<p>&nbsp;</p>
733
734<div class="container-fluid max-width-800">
735<div class="access-hub-cta-1" style="display:block !important;">
736<div class="icon">&nbsp;</div>
737
738<div class="card">
739<div class="card-body">
740<div class="cta-4-body">
741<p style="text-align:center;">Getting THIOLA EC tablets is simple through the Total Care HUB. Download the enrollment form today and talk to your doctor about getting started.</p>
742</div>
743</div>
744
745<div class="card-footer"><a class="btn-cta btn btn-lg btn-xl btn-primary" gtm-data-action="navigate" gtm-data-category="subnav-total-care-hub" gtm-data-label="enrollment-form-myhub" href="/sites/default/files/pdfs/THI460v4_THIOLA_EC_EnrollmentForm_20241210.pdf">Get THIOLA EC</a></div>
746</div>
747</div>
748</div>
749
750<p>&nbsp;</p>
751
752          </div>
753        
754        
755      </section>
756    
757    <div class="container body-content">
758      <div class="row">
759                
760                        <section class="col-sm-12">
761
762                    
763                    
764                    
765                                              
766                      
767                                <a id="main-content"></a>
768              <div class="region region-content">
769      <article data-history-node-id="5" role="article" about="/total-care-hub" class="total-care-hub-page is-promoted full clearfix">
770
771  
772    
773
774  <div class="content">
775    
776  </div>
777
778</article>
779
780<section id="block-isi" class="block block-block-content block-block-content1f12c641-ec8d-4e74-acdd-ac391bf003b5 clearfix">
781  
782    
783
784      
785            <div class="field field--name-body field--type-text-with-summary field--label-hidden field--item"><div class="new-content">
786<h4 class="isi-headline-top">THIOLA EC<sup>®</sup> (tiopronin, delayed-release tablets)</h4>
787
788<h3 class="isi-headline-top">Important Safety Information</h3>
789
790<h4>What is THIOLA EC<sup>®</sup> (tiopronin, delayed-release tablets)?</h4>
791
792<p>THIOLA EC is a prescription medication provided in a delayed-release tablet. It is used in combination with high fluid intake, alkali (low acid), and dietary changes to help prevent the formation of one type (cystine) of kidney stones in certain adult and pediatric patients that weigh at least 44 pounds (20 kg) and who do not respond to these measures alone.</p>
793
794<h4>Who should not take THIOLA EC?</h4>
795
796<p><strong>THIOLA EC should not be taken if you:</strong></p>
797
798<ul><li>Are allergic to THIOLA EC, or any of the ingredients in THIOLA EC.</li>
799</ul><h4>What should I tell my doctor before taking THIOLA EC?</h4>
800
801<p><strong>THIOLA EC may not be right for you. Before taking THIOLA EC, tell your doctor about:</strong></p>
802
803<ul><li>all health conditions you may have and any medications you may be taking</li>
804	<li>if you are pregnant or plan to become pregnant</li>
805	<li>if you are breastfeeding or plan to breastfeed</li>
806</ul><h4>What should I avoid while taking THIOLA EC?</h4>
807
808<p>You should avoid drinking alcohol 2 hours before and 3 hours after taking THIOLA EC.</p>
809
810<h4>What are possible side effects of THIOLA EC?</h4>
811
812<p><strong>Serious Side Effects:</strong> THIOLA EC can cause proteinuria (high amounts of protein in urine), including serious kidney problems, and hypersensitivity reactions (including fever, rash, joint pain and enlarged or swollen lymph nodes).</p>
813
814<p><strong>Most Common Side Effects:</strong> Nausea, diarrhea or soft stools, sores in the mouth, rash, fatigue, fever, muscle or joint pain, high amounts of protein in urine, vomiting.</p>
815
816<p>These are not all the possible side effects of THIOLA EC. Call your doctor for medical advice about side effects.</p>
817
818<p>You may report negative side effects to Travere Therapeutics Medical Information at <a class="no-wrap" href="tel:1-877-659-5518">1-877-659-5518</a>, or to the FDA at <a class="no-wrap" gtm-data-action="call" gtm-data-category="global-footer" gtm-data-label="fda" href="1-800-FDA-1088">1-800-FDA-1088</a> or <a gtm-data-action="navigate" gtm-data-category="button-homepage" gtm-data-label="fda" href="http://www.fda.gov/medwatch" target="_blank">www.fda.gov/medwatch</a>.</p>
819
820<p><strong><a gtm-data-action="download" gtm-data-category="global-footer" gtm-data-label="PI" href="/sites/default/files/pdfs/nda/ThiolaEC_PI.pdf" target="_blank">Please click here for full Prescribing Information</a> and additional Important Safety Information.</strong></p>
821</div>
822
823<p>
823 </p>
824
825<div class="new-content">
826<h4 class="isi-headline-top">THIOLA<sup>®</sup> (tiopronin)</h4>
827
828<h3 class="isi-headline-top">Important Safety Information</h3>
829
830<h4>What is THIOLA<sup>®</sup> (tiopronin tablets)?</h4>
831
832<p>THIOLA is a prescription medicine. It is used in combination with high fluid intake, alkali (low acid), and dietary changes to help prevent the formation of one type (cystine) of kidney stone in certain adult and pediatric patients that weigh at least 44 pounds (20 kg) and who do not respond to these measures alone.</p>
833
834<h4>Who should not take THIOLA?</h4>
835
836<p><strong>THIOLA should not be taken if you:</strong></p>
837
838<ul><li>Are allergic to THIOLA, or any of the ingredients in THIOLA.</li>
839</ul><h4>What should I tell my doctor before taking THIOLA?</h4>
840
841<p><strong>THIOLA may not be right for you. Before taking THIOLA, tell your doctor about:</strong></p>
842
843<ul><li>all health conditions you may have and any medications you may be taking</li>
844	<li>if you are pregnant or plan to become pregnant</li>
845	<li>if you are breastfeeding or plan to breastfeed</li>
846</ul><h4>What are possible side effects of THIOLA?</h4>
847
848<p><strong>Serious Side Effects: </strong> THIOLA can cause proteinuria (high amounts of protein in urine), including serious kidney problems, and hypersensitivity reactions (including fever, rash, joint pain and enlarged or swollen lymph nodes).</p>
849
850<p><strong>Most Common Side Effects: </strong> Nausea, diarrhea or soft stools, sores in the mouth, rash, fatigue, fever, muscle or joint pain, high amounts of protein in urine, vomiting.</p>
851
852<p>These are not all the possible side effects of THIOLA. Call your doctor for medical advice about side effects.</p>
853
854<p>You may report negative side effects to Travere Therapeutics Medical Information at <a class="no-wrap" href="tel:1-877-659-5518">1-877-659-5518</a>, or to the FDA at <a class="no-wrap" href="tel:1-800-FDA-1088">1-800-FDA-1088</a> or <a gtm-data-action="navigate" gtm-data-category="button-footer" gtm-data-label="fda" href="https://www.fda.gov/medwatch" target="_blank">www.fda.gov/medwatch</a>.</p>
855
856<p><strong><a gtm-data-action="navigate" gtm-data-category="link-footer" gtm-data-label="see-copay-terms" href="/sites/default/files/pdfs/nda/Thiola_PI.pdf" target="_blank">Please click here for full Prescribing Information</a> and additional Important Safety Information.</strong></p>
857</div>
858
859<p> </p>
860</div>
861      
862  </section>
863
864
865  </div>
866
867                  </section>
868
869                      </div>
870    </div>
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872
873  <div id="scroll-indicator-container">
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883            
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885  
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910      
911            <div class="field field--name-body field--type-text-with-summary field--label-hidden field--item"><p>© 2021 Travere Therapeutics, Inc. THIOLA<sup>®</sup> and THIOLA EC<sup>®</sup> are registered trademarks of Mission Pharmacal Company. Total Care HUB is a registered trademark of Travere Therapeutics, Inc. All rights reserved. THI465v10<br />
912This site is intended only for US residents.</p>
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930      <h2 class="text-center">Stay connected!</h2>
931      <p class="text-center">Sign up to receive information about THIOLA<sup>&reg;</sup> EC (tiopronin) tablets and cystinuria.</p>
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945        <div style="height:90px;">
946          <label for="formInputCurrentlyTakingThiola1" class="form-label">Are you currently taking THIOLA EC?</label>
947          <label class="radio-inline">
948            <input type="radio" id="formInputCurrentlyTakingThiola1" name="currently_taking_thiola" value="yes" required data-parsley-errors-container="#radio-errors">
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988        <select class="form-control" data-parsley-validate-if-empty="true" data-parsley-required-if="step2" data-conditionally-required-id="step2" id="formInputState" name="state">
989          <option value="">Select state...</option>
990          <option value="AL">Alabama</option>
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1036          <option value="VA">Virginia</option>
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1038          <option value="WV">West Virginia</option>
1039          <option value="WI">Wisconsin</option>
1040          <option value="WY">Wyoming</option>
1041        </select>
1042      </div>
1043      <div class="form-group">
1044        <label for="formInputZip" class="form-label">ZIP code</label>
1045        <input type="text" class="form-control" data-parsley-validate-if-empty="true" data-parsley-required-if="step2" data-conditionally-required-id="step2" id="formInputZip" name="zip" data-conditionally-required-pattern="(^\d{5}$)|(^\d{5}-\d{4}$)">
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1050  <div id="form-success" class="text-center" style="display:none;">
1051    <h1>Thank you for signing up!</h1>
1052    <p style="margin:30px auto;">Check your email for information and resources about treatment with THIOLA<sup>&reg;</sup> EC (tiopronin) tablets.</p>
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1064
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1067
1068<p>The site you are about to enter is intended only for US healthcare professionals.</p></div>
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1103
1104      
1105            <div class="field field--name-body field--type-text-with-summary field--label-hidden field--item"><h2 class="clr-dark pd-115">Connect with others in the cystinuria community</h2>
1106
1107<p class="fs-18 pd-62 lh-28"><strong>You don’t have to go it alone.</strong> If you have cystinuria, or care for someone who does, these events are for you. By meeting others at a live event, you can share thoughts, exchange experiences, and equip yourself with practical advice from others who know what you’re going through. Get more support by attending an event near you.</p>
1108</div>
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1117    <section class="views-element-container block block-views block-views-blockevents-block-1 clearfix" id="block-views-block-events-block-1-2">
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1127  
1128          </div>
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1132
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1134
1135	          <div>
1136              <h2 class="clr-dark  poc-event-text">By clicking the [RSVP here] buttons, you will be redirected to a website that hosts the Event Registration, and your personal data will be used to register you for the webinar. For more information, please review our 
1136<a href="http://travere.com/privacy/">Privacy Policies</a>.</h2>
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1147<div id="sqhtest">page--total_care_hub_page.html.twig</div>
1148
1149<div id="global-isi-container" class="global-isi-container">
1150    <div>
1151        <div>
1152            <div>
1153                <div class="global-isi-text">
1154                    <div>
1155                        <div class="global-isi-mobile-container">
1156                            <div>
1157                                <h3 class="isi-headline-top" style="margin: 0;"><strong>THIOLA EC<sup>®</sup> (tiopronin, delayed-release tablets)</strong></h3>
1158                                <h2 class="isi-headline-top" style="margin: 0;"><strong>Important Safety Information</strong></h2>
1159                            </div>
1160
1161                            <div>
1162                                <h3 style="margin: 0;"><strong>What is THIOLA EC<sup>®</sup> (tiopronin, delayed-release tablets)?</strong></h3>
1163                                <p>THIOLA EC is a prescription medication provided in a delayed-release tablet. It is used in combination with high fluid intake, alkali (low acid), and dietary changes to help prevent the formation of one type (cystine) of kidney stones in certain adult and pediatric patients that weigh at least 44 pounds (20 kg) and who do not respond to these measures alone.</p>
1164                            </div>
1165
1166                            <div>
1167                                <h3 style="margin: 0;"><strong>Who should not take THIOLA EC?</strong></h3>
1168                                <p class="question"><strong>THIOLA EC should not be taken if you:</strong></p>
1169                                <ul>
1170                                    <li>Are allergic to THIOLA EC, or any of the ingredients in THIOLA EC.</li>
1171                                </ul>
1172                            </div>
1173                        </div>
1174
1175                        <h3><strong>What should I tell my doctor before taking THIOLA EC?</strong></h3>
1176
1177                        <p class="question"><strong>THIOLA EC may not be right for you. Before taking THIOLA EC, tell your doctor about:</strong></p>
1178
1179                        <ul>
1180                            <li>all health conditions you may have and any medications you may be taking</li>
1181                            <li>if you are pregnant or plan to become pregnant</li>
1182                            <li>if you are breastfeeding or plan to breastfeed</li>
1183                        </ul>
1184
1185                        <h3><strong>What should I avoid while taking THIOLA EC?</strong></h3>
1186
1187                        <p>You should avoid drinking alcohol 2 hours before and 3 hours after taking THIOLA EC.</p>
1188
1189                        <h3><strong>What are possible side effects of THIOLA EC?</strong></h3>
1190
1191                        <p><strong>Serious Side Effects:</strong> THIOLA EC can cause proteinuria (high amounts of protein in urine), including serious kidney problems, and hypersensitivity reactions (including fever, rash, joint pain and enlarged or swollen lymph nodes).</p>
1192
1193                        <p><strong>Most Common Side Effects:</strong> Nausea, diarrhea or soft stools, sores in the mouth, rash, fatigue, fever, muscle or joint pain, high amounts of protein in urine, vomiting.</p>
1194
1195                        <p>These are not all the possible side effects of THIOLA EC. Call your doctor for medical advice about side effects.</p>
1196
1197                        <p>You may report negative side effects to Travere Therapeutics Medical Information at <a class="no-wrap" href="tel:0018776595518">1-877-659-5518</a>, or to the FDA at <a class="no-wrap" href="tel:18003321088">1-800-FDA-1088</a> or <a href="https://www.fda.gov/medwatch" target="_blank">www.fda.gov/medwatch</a>.</p>
1198
1199                        <p><strong class="isi-link"><a href="/sites/default/files/pdfs/nda/ThiolaEC_PI.pdf" target="_blank">Please click here for full Prescribing Information</a> and additional Important Safety Information.</strong></p>
1200
1201                        <div><p>&nbsp;</p></div>
1202
1203                        <h3 class="isi-headline-top"><strong>THIOLA<sup>®</sup> (tiopronin tablets)</strong></h3>
1204
1205                        <h2 class="isi-headline-top"><strong>Important Safety Information</strong></h2>
1206
1207                        <h3><strong>What is THIOLA<sup>®</sup> (tiopronin tablets)?</strong></h3>
1208
1209                        <p>THIOLA is a prescription medicine. It is used in combination with high fluid intake, alkali (low acid), and dietary changes to help prevent the formation of one type (cystine) of kidney stones in certain adult and pediatric patients that weigh at least 44 pounds (20 kg) and who do not respond to these measures alone.</p>
1210
1211                        <h3><strong>Who should not take THIOLA?</strong></h3>
1212
1213                        <p class="question"><strong>THIOLA should not be taken if you:</strong></p>
1214
1215                        <ul>
1216                            <li>Are allergic to THIOLA, or any of the ingredients in THIOLA.</li>
1217                        </ul>
1218
1219                        <h3><strong>What should I tell my doctor before taking THIOLA?</strong></h3>
1220
1221                        <p class="question"><strong>THIOLA may not be right for you. Before taking THIOLA, tell your doctor about:</strong></p>
1222
1223                        <ul>
1224                            <li>all health conditions you may have and any medications you may be taking</li>
1225                            <li>if you are pregnant or plan to become pregnant</li>
1226                            <li>if you are breastfeeding or plan to breastfeed</li>
1227                        </ul>
1228
1229                        <h3><strong>What are possible side effects of THIOLA?</strong></h3>
1230
1231                        <p><strong>Serious Side Effects: </strong> THIOLA can cause proteinuria (high amounts of protein in urine), including serious kidney problems, and hypersensitivity reactions (including fever, rash, joint pain and enlarged or swollen lymph nodes).</p>
1232
1233                        <p><strong>Most Common Side Effects: </strong> Nausea, diarrhea or soft stools, sores in the mouth, rash, fatigue, fever, muscle or joint pain, high amounts of protein in urine, vomiting.</p>
1234
1235                        <p>These are not all the possible side effects of THIOLA. Call your doctor for medical advice about side effects.</p>
1236
1237                        <p>You may report negative side effects to Travere Therapeutics Medical Information at <a class="no-wrap" href="tel:0018776595518">1-877-659-5518</a>, or to the FDA at <a class="no-wrap" href="tel:18003321088">1-800-FDA-1088</a> or <a href="https://www.fda.gov/medwatch" target="_blank">www.fda.gov/medwatch</a>.</p>
1238
1239                        <p><strong class="isi-link"><a href="/sites/default/files/pdfs/nda/Thiola_PI.pdf" target="_blank">Please click here for full Prescribing Information</a> and additional Important Safety Information.</strong></p>
1240                    </div>
1241                </div>
1242            </div>
1243        </div>
1244        <div class="open-close-button"></div>
1245        <div></div>
1246    </div>
1247</div>
1248
1249
1250<div id="global-isi-container-fullscreen" class="global-isi-container-fullscreen">
1251    <div class="isi-overlay-scroller">
1252        <div class="open-close-button"></div>
1253        <div spacing="30" class="sc-bBXqnf fWUuMw">
1254            <div></div>
1255        </div>
1256
1257        <div>
1258            <div class="thiola-ec-tiopronin-content">
1259                <h3 class="isi-headline-top"><strong>THIOLA EC<sup>®</sup> (tiopronin, delayed-release tablets)</strong></h3>
1260
1261                <h2 class="isi-headline-top"><strong>Important Safety Information</strong></h2>
1262
1263                <h3><strong>What is THIOLA EC<sup>®</sup> (tiopronin, delayed-release tablets)?</strong></h3>
1264
1265                <p>THIOLA EC is a prescription medication provided in a delayed-release tablet. It is used in combination with high fluid intake, alkali (low acid), and dietary changes to help prevent the formation of one type (cystine) of kidney stones in certain adult and pediatric patients that weigh at least 44 pounds (20 kg) and who do not respond to these measures alone.</p>
1266
1267                <h3><strong>Who should not take THIOLA EC?</strong></h3>
1268
1269                <p class="question"><strong>THIOLA EC should not be taken if you:</strong></p>
1270
1271                <ul>
1272                    <li>Are allergic to THIOLA EC, or any of the ingredients in THIOLA EC.</li>
1273                </ul>
1274
1275                <h3><strong>What should I tell my doctor before taking THIOLA EC?</strong></h3>
1276
1277                <p class="question"><strong>THIOLA EC may not be right for you. Before taking THIOLA EC, tell your doctor about:</strong></p>
1278
1279                <ul>
1280                    <li>all health conditions you may have and any medications you may be taking</li>
1281                    <li>if you are pregnant or plan to become pregnant</li>
1282                    <li>if you are breastfeeding or plan to breastfeed</li>
1283                </ul>
1284
1285                <h3><strong>What should I avoid while taking THIOLA EC?</strong></h3>
1286
1287                <p>You should avoid drinking alcohol 2 hours before and 3 hours after taking THIOLA EC.</p>
1288
1289                <h3><strong>What are possible side effects of THIOLA EC?</strong></h3>
1290
1291                <p><strong>Serious Side Effects:</strong> THIOLA EC can cause proteinuria (high amounts of protein in urine), including serious kidney problems, and hypersensitivity reactions (including fever, rash, joint pain and enlarged or swollen lymph nodes).</p>
1292
1293                <p><strong>Most Common Side Effects:</strong> Nausea, diarrhea or soft stools, sores in the mouth, rash, fatigue, fever, muscle or joint pain, high amounts of protein in urine, vomiting.</p>
1294
1295                <p>These are not all the possible side effects of THIOLA EC. Call your doctor for medical advice about side effects.</p>
1296
1297                <p>You may report negative side effects to Travere Therapeutics Medical Information at <a class="no-wrap" href="tel:0018776595518">1-877-659-5518</a>, or to the FDA at <a class="no-wrap" href="tel:18003321088">1-800-FDA-1088</a> or <a href="https://www.fda.gov/medwatch" target="_blank">www.fda.gov/medwatch</a>.</p>
1298
1299                <p><strong class="isi-link"><a href="/sites/default/files/pdfs/nda/ThiolaEC_PI.pdf" target="_blank">Please click here for full Prescribing Information</a> and additional Important Safety Information.</strong></p>
1300            </div>
1301
1302            <div><p>&nbsp;</p></div>
1303
1304            <div class="thiola-tiopronin-content">
1305                <h3 class="isi-headline-top"><strong>THIOLA<sup>®</sup> (tiopronin tablets)</strong></h3>
1306
1307                <h2 class="isi-headline-top"><strong>Important Safety Information</strong></h2>
1308
1309                <h3><strong>What is THIOLA<sup>®</sup> (tiopronin tablets)?</strong></h3>
1310
1311                <p>THIOLA is a prescription medicine. It is used in combination with high fluid intake, alkali (low acid), and dietary changes to help prevent the formation of one type (cystine) of kidney stones in certain adult and pediatric patients that weigh at least 44 pounds (20 kg) and who do not respond to these measures alone.</p>
1312
1313                <h3><strong>Who should not take THIOLA?</strong></h3>
1314
1315                <p class="question"><strong>THIOLA should not be taken if you:</strong></p>
1316
1317                <ul>
1318                    <li>Are allergic to THIOLA, or any of the ingredients in THIOLA.</li>
1319                </ul>
1320
1321                <h3><strong>What should I tell my doctor before taking THIOLA?</strong></h3>
1322
1323                <p class="question"><strong>THIOLA may not be right for you. Before taking THIOLA, tell your doctor about:</strong></p>
1324
1325                <ul>
1326                    <li>all health conditions you may have and any medications you may be taking</li>
1327                    <li>if you are pregnant or plan to become pregnant</li>
1328                    <li>if you are breastfeeding or plan to breastfeed</li>
1329                </ul>
1330
1331                <h3><strong>What are possible side effects of THIOLA?</strong></h3>
1332
1333                <p><strong>Serious Side Effects: </strong> THIOLA can cause proteinuria (high amounts of protein in urine), including serious kidney problems, and hypersensitivity reactions (including fever, rash, joint pain and enlarged or swollen lymph nodes).</p>
1334
1335                <p><strong>Most Common Side Effects: </strong> Nausea, diarrhea or soft stools, sores in the mouth, rash, fatigue, fever, muscle or joint pain, high amounts of protein in urine, vomiting.</p>
1336
1337                <p>These are not all the possible side effects of THIOLA. Call your doctor for medical advice about side effects.</p>
1338
1339                <p>You may report negative side effects to Travere Therapeutics Medical Information at <a class="no-wrap" href="tel:0018776595518">1-877-659-5518</a>, or to the FDA at <a class="no-wrap" href="tel:18003321088">1-800-FDA-1088</a> or <a href="https://www.fda.gov/medwatch" target="_blank">www.fda.gov/medwatch</a>.</p>
1340
1341                <p><strong class="isi-link"><a href="/sites/default/files/pdfs/nda/Thiola_PI.pdf" target="_blank">Please click here for full Prescribing Information</a> and additional Important Safety Information.</strong></p>
1342            </div>
1343        </div>
1344
1345    </div>
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vendor: 1 bytes, line 1378
1378
1379<script src="/themes/thiola/bootstrap/assets/javascripts/bootstrap/alert.js?tin0ed"></script>
vendor: 1 bytes, line 1379
1379
1380<script src="/themes/thiola/bootstrap/assets/javascripts/bootstrap/button.js?tin0ed"></script>
vendor: 1 bytes, line 1380
1380
1381<script src="/themes/thiola/bootstrap/assets/javascripts/bootstrap/carousel.js?tin0ed"></script>
vendor: 1 bytes, line 1381
1381
1382<script src="/themes/thiola/bootstrap/assets/javascripts/bootstrap/collapse.js?tin0ed"></script>
vendor: 1 bytes, line 1382
1382
1383<script src="/themes/thiola/bootstrap/assets/javascripts/bootstrap/dropdown.js?tin0ed"></script>
vendor: 1 bytes, line 1383
1383
1384<script src="/themes/thiola/bootstrap/assets/javascripts/bootstrap/modal.js?tin0ed"></script>
vendor: 1 bytes, line 1384
1384
1385<script src="/themes/thiola/bootstrap/assets/javascripts/bootstrap/tooltip.js?tin0ed"></script>
vendor: 1 bytes, line 1385
1385
1386<script src="/themes/thiola/bootstrap/assets/javascripts/bootstrap/popover.js?tin0ed"></script>
vendor: 1 bytes, line 1386
1386
1387<script src="/themes/thiola/bootstrap/assets/javascripts/bootstrap/scrollspy.js?tin0ed"></script>
vendor: 1 bytes, line 1387
1387
1388<script src="/themes/thiola/bootstrap/assets/javascripts/bootstrap/tab.js?tin0ed"></script>
vendor: 1 bytes, line 1388
1388
1389<script src="/themes/thiola/bootstrap/assets/javascripts/bootstrap/transition.js?tin0ed"></script>
vendor: 1 bytes, line 1389
1389
1390<script src="//api.2amigos.us/js/thiola-dosing-calculator.min.js"></script>
vendor: 1 bytes, line 1390
1390
1391<script src="/themes/thiola/js/parsley.js?tin0ed"></script>
vendor: 1 bytes, line 1391
1391
1392<script src="/themes/thiola/js/parsley.config.js?tin0ed"></script>
vendor: 1 bytes, line 1392
1392
1393<script src="/themes/thiola/js/smooth-scroll.js?tin0ed"></script>
vendor: 1 bytes, line 1393
1393
1394<script src="/themes/thiola/js/jquery.matchHeight.js?tin0ed"></script>
vendor: 1 bytes, line 1394
1394
1395<script src="/themes/thiola/js/jquery.waypoints.js?tin0ed"></script>
vendor: 1 bytes, line 1395
1395
1396<script src="/themes/thiola/js/js.cookie.js?tin0ed"></script>
vendor: 1 bytes, line 1396
1396
1397<script src="/themes/thiola/js/timer.js?tin0ed"></script>
vendor: 1 bytes, line 1397
1397
1398<script src="/themes/thiola/js/ua-parser.min.js?tin0ed"></script>
vendor: 1 bytes, line 1398
1398
1399<script src="/themes/thiola/js/main.js?tin0ed"></script>
1399
1400
1401  </body>
1402</html>

Line numbers count LF bytes from the start of the resource, as the search results do. Vendor segments are library code the classifier recognised; they are stored but not indexed. Bytes are shown as Latin1 characters, one per byte.