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128            <div class="ms-md-5">
129                <h1 class="fw-bold pb-2 mb-2 mb-md-0"><a href="/" style="color: black; text-decoration: none;">Deafness Variation Database</a></h1>
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138<div class="container mx-auto" style="max-width: 700px;">
139        <h3 class="fw-bold mt-4 border-bottom pb-2">Search Variant Data</h3>
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148            name="query"
149            placeholder="Search genes or coordinates by chr:pos, chr:pos-range, chr:pos:ref>alt"
150            value=""
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175</form>
176        <div class="mt-3">
177            <h5>Browse by Gene</h5>
178            <div class="home-letters">
179                 <div class="letters">
180    <div class="letter-flex">
181                    <a 
182                href="https://deafnessvariationdatabase.org/genes/a"
183                class="letter "
184            >
185                A
186            </a>
187                    <a 
188                href="https://deafnessvariationdatabase.org/genes/b"
189                class="letter "
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191                B
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193                    <a 
194                href="https://deafnessvariationdatabase.org/genes/c"
195                class="letter "
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197                C
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199                    <a 
200                href="https://deafnessvariationdatabase.org/genes/d"
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206                href="https://deafnessvariationdatabase.org/genes/e"
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209                E
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212                href="https://deafnessvariationdatabase.org/genes/f"
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215                F
216            </a>
217                    <a 
218                href="https://deafnessvariationdatabase.org/genes/g"
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221                G
222            </a>
223                    <a 
224                href="https://deafnessvariationdatabase.org/genes/h"
225                class="letter "
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227                H
228            </a>
229                    <a 
230                href="https://deafnessvariationdatabase.org/genes/i"
231                class="letter "
232            >
233                I
234            </a>
235                    <a 
236                href="#"
237                class="letter disabled-letter"
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239                J
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241                    <a 
242                href="https://deafnessvariationdatabase.org/genes/k"
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260                href="https://deafnessvariationdatabase.org/genes/n"
261                class="letter "
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266                href="https://deafnessvariationdatabase.org/genes/o"
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281                Q
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284                href="https://deafnessvariationdatabase.org/genes/r"
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287                R
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290                href="https://deafnessvariationdatabase.org/genes/s"
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296                href="https://deafnessvariationdatabase.org/genes/t"
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299                T
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301                    <a 
302                href="https://deafnessvariationdatabase.org/genes/u"
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305                U
306            </a>
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308                href="#"
309                class="letter disabled-letter"
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311                V
312            </a>
313                    <a 
314                href="https://deafnessvariationdatabase.org/genes/w"
315                class="letter "
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317                W
318            </a>
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323                X
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325                    <a 
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329                Y
330            </a>
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335                Z
336            </a>
337            </div>
338</div>            </div>
339        </div>
340    </div>
341</div>
342<br>
343<div class="container w-100" >
344<h3 class="fw-bold mt-4 border-bottom pb-2"> About</h3>
345<div class="width500">
346    <p>
347        The <strong>Deafness Variation Database (DVD)</strong> is a public, expert-curated resource of genetic 
348        variation in genes associated with hearing loss, built and maintained by the <a href="https://morl.lab.uiowa.edu" class="ui-links" target=_blank>Molecular 
349        Otolaryngology &amp; Renal Research Laboratories (MORL)</a> 
350        at the University of Iowa and launched in 2011.
351    </p>
352    <p>
353        Our mission is to advance accurate classification of deafness-associated genetic variation by rigorously collating, annotating, classifying, 
354        and openly sharing evidence. We aim to reduce uncertainty and enable accurate diagnosis and informed clinical decision-making.
355    </p>
356    <p>
357        <strong>Current release DVD v9.2</strong> summarizes all known variants across 224 
358        deafness-associated genes represented on 
359        <a href="https://morl.lab.uiowa.edu/otoscope-panel-genes" class="ui-links" target=_blank>OtoSCOPE&#174;</a>, MORL’s comprehensive 
360        genetic screening platform for deafness.
361        The DVD collates data from major public resources, annotates with gene/transcript, population, functional, and clinical context, and classifies 
362        each variant to produce a single, evidence-based assessment. Classifications are reviewed by genetic hearing-loss experts at the MORL. See 
363        <a href="sources" class="ui-links" target=_blank>sources</a> and our landmark paper, 
364        <a href="https://doi.org/10.1016/j.ajhg.2018.08.006" class="ui-links" target=_blank>Genomic Landscape and Mutational Signatures of Deafness-Associated Genes</a> for details.
365    </p>
366        The DVD is <strong>continually curated</strong>. This version reflects our most recent interpretations.
367    </p>
368    <p>
369        The data are freely available. When using the DVD, please review our 
369<a href="references" class="ui-links" target=_blank>citation policy</a>. 
370    </p>
371    <p>
372        All content is copyrighted by the MORL at The University of Iowa.
373    </p>
374    <p>
375        To suggest an update or add a gene or variant, <a href="/contact" class="ui-links" target=_blank>contact us</a>.
376    </p>
377    <p>
378        Supported in part by R01 DC012049
379    </p>
380
381    <br>
382    <p>Supported in part by</br></br><a href="https://www.nidcd.nih.gov/">R01 DC012049</a></p></br>
383    <a href="https://www.nidcd.nih.gov/">
384        <img
385            src="https://deafnessvariationdatabase.org/assets/img/logo-NIDCD.png"
386            style="max-height:50px;"
387            title="National Institute on Deafness and Other Communication Disorders"
388            alt="NIDCD Logo"
389        >
390    </a>
391</div>
392</div>
393<div class="mx-auto" style="width: 600px">
394    </br>
395    <p>
396        <b>Follow Us!</b>
397    </p>
398    <a href="https://twitter.com/MORL_UIowa" title="MORL UIowa Twitter">
399        <img src="https://deafnessvariationdatabase.org/assets/img/twitter.png" height="5%" width="5%" alt="Twitter" hspace="10" class="float-left" />
400    </a>
401    <a href="https://www.facebook.com/UIMORL" title="MORL UIowa Facebook">
402        <img src="https://deafnessvariationdatabase.org/assets/img/facebook.png" height="5%" width="5%" alt="Facebook" hspace="10" class="float-center" />
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420            class="form-control flex-grow-1 search-hover h-100" 
421            name="query"
422            placeholder="Search genes or coordinates by chr:pos, chr:pos-range, chr:pos:ref>alt"
423            value=""
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426            <select name="build" class="form-select">
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457<div class="sidebar" id="sidebar">
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463    <div class="sidebar-contents mt-3">
464        <div class="letter-table">
465            <h6 class="border-bottom" style="color:white;">Browse by Gene</h6>
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467    <div class="letter-flex">
468                    <a 
469                href="https://deafnessvariationdatabase.org/genes/a"
470                class="letter "
471            >
472                A
473            </a>
474                    <a 
475                href="https://deafnessvariationdatabase.org/genes/b"
476                class="letter "
477            >
478                B
479            </a>
480                    <a 
481                href="https://deafnessvariationdatabase.org/genes/c"
482                class="letter "
483            >
484                C
485            </a>
486                    <a 
487                href="https://deafnessvariationdatabase.org/genes/d"
488                class="letter "
489            >
490                D
491            </a>
492                    <a 
493                href="https://deafnessvariationdatabase.org/genes/e"
494                class="letter "
495            >
496                E
497            </a>
498                    <a 
499                href="https://deafnessvariationdatabase.org/genes/f"
500                class="letter "
501            >
502                F
503            </a>
504                    <a 
505                href="https://deafnessvariationdatabase.org/genes/g"
506                class="letter "
507            >
508                G
509            </a>
510                    <a 
511                href="https://deafnessvariationdatabase.org/genes/h"
512                class="letter "
513            >
514                H
515            </a>
516                    <a 
517                href="https://deafnessvariationdatabase.org/genes/i"
518                class="letter "
519            >
520                I
521            </a>
522                    <a 
523                href="#"
524                class="letter disabled-letter"
525            >
526                J
527            </a>
528                    <a 
529                href="https://deafnessvariationdatabase.org/genes/k"
530                class="letter "
531            >
532                K
533            </a>
534                    <a 
535                href="https://deafnessvariationdatabase.org/genes/l"
536                class="letter "
537            >
538                L
539            </a>
540                    <a 
541                href="https://deafnessvariationdatabase.org/genes/m"
542                class="letter "
543            >
544                M
545            </a>
546                    <a 
547                href="https://deafnessvariationdatabase.org/genes/n"
548                class="letter "
549            >
550                N
551            </a>
552                    <a 
553                href="https://deafnessvariationdatabase.org/genes/o"
554                class="letter "
555            >
556                O
557            </a>
558                    <a 
559                href="https://deafnessvariationdatabase.org/genes/p"
560                class="letter "
561            >
562                P
563            </a>
564                    <a 
565                href="#"
566                class="letter disabled-letter"
567            >
568                Q
569            </a>
570                    <a 
571                href="https://deafnessvariationdatabase.org/genes/r"
572                class="letter "
573            >
574                R
575            </a>
576                    <a 
577                href="https://deafnessvariationdatabase.org/genes/s"
578                class="letter "
579            >
580                S
581            </a>
582                    <a 
583                href="https://deafnessvariationdatabase.org/genes/t"
584                class="letter "
585            >
586                T
587            </a>
588                    <a 
589                href="https://deafnessvariationdatabase.org/genes/u"
590                class="letter "
591            >
592                U
593            </a>
594                    <a 
595                href="#"
596                class="letter disabled-letter"
597            >
598                V
599            </a>
600                    <a 
601                href="https://deafnessvariationdatabase.org/genes/w"
602                class="letter "
603            >
604                W
605            </a>
606                    <a 
607                href="#"
608                class="letter disabled-letter"
609            >
610                X
611            </a>
612                    <a 
613                href="#"
614                class="letter disabled-letter"
615            >
616                Y
617            </a>
618                    <a 
619                href="#"
620                class="letter disabled-letter"
621            >
622                Z
623            </a>
624            </div>
625</div>        </div>
626        <br>
627        <dl class="nav flex-column">
628            <dt class="nav-item"><a class="nav-link" href="/">Home</a></dt>
629            <dt class="nav-item"><a class="nav-link" href="/new">What's New</a></dt>
630            <dt class="nav-item"><a class="nav-link" href="/classification">Classification</a></dt>
631            <dt class="nav-item"><a class="nav-link" href="/nomenclature">Nomenclature</a></dt>
632            <dt class="nav-item"><a class="nav-link" href="/sources">Sources</a></dt>
633            <dt class="nav-item"><a class="nav-link" href="/references">Cite Us</a></dt>
634            <dt class="nav-item"><a class="nav-link" href="/downloads">Downloads</a></dt>
635            <dt class="nav-item"><a class="nav-link" href="/help">Help</a></dt>
636            <dt class="nav-item"><a class="nav-link" href="/contact">Contact Us</a></dt>
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645                <p class="mb-0">
646                    &lt;p&gt;&lt;span&gt;&amp;copy; 2011&amp;ndash;2026&lt;/span&gt; &lt;a href=&quot;http://www.medicine.uiowa.edu/morl/&quot; title=&quot;MORL Homepage&quot;&gt;The Molecular Otolaryngology and Renal Research Laboratories&lt;/a&gt; at &lt;a href=&quot;http://www.uiowa.edu&quot; title=&quot;University of Iowa Homepage&quot;&gt;The University of Iowa&lt;/a&gt;&lt;/p&gt;
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655    function toggleSidebar() {
656        document.getElementById('sidebar').classList.toggle('show');
657        document.getElementById('sidebarOverlay').classList.toggle('show');
658    }
659
660    function toggleSearchModal() {
661        document.getElementById('searchModal').classList.toggle('show');
662    }
663</script>
663
664</body>
665</html>

Line numbers count LF bytes from the start of the resource, as the search results do. Vendor segments are library code the classifier recognised; they are stored but not indexed. Bytes are shown as Latin1 characters, one per byte.