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1<!DOCTYPE html><html lang="en"><head><meta charSet="utf-8"/><meta name="viewport" content="width=device-width, initial-scale=1"/><link rel="preload" as="image" href="/assets/phasezero-logo-BEy02M1R.png"/><link rel="preload" as="image" href="/assets/phasezero-dashboard-vNEvhI2G.png"/><link rel="stylesheet" href="/assets/styles-nHABoWFz.css" data-precedence="default"/><title>PhaseZero — Therapeutic Intelligence OS</title><meta name="author" content="PhaseZero"/><meta property="og:type" content="website"/><meta name="twitter:card" content="summary"/><meta name="twitter:site" content="@Lovable"/><meta name="description" content="AI-native scientific diligence cockpit for ADC opportunities. Find therapeutic alpha before consensus forms."/><meta property="og:title" content="PhaseZero — Therapeutic Intelligence OS"/><meta property="og:description" content="AI-native scientific diligence cockpit for ADC opportunities."/><link rel="modulepreload" href="/assets/index-iAVlVxvB.js"/><link rel="modulepreload" href="/assets/index-ZQMkKkF-.js"/><link rel="modulepreload" href="/assets/Sidebar-BstMbomz.js"/><link rel="modulepreload" href="/assets/arrow-right-BpZNrPHd.js"/><link rel="modulepreload" href="/assets/flask-conical-Dut0J8fI.js"/></head><body><!--$--><div style="--sidebar-width:16rem;--sidebar-width-icon:3rem" class="group/sidebar-wrapper flex min-h-svh w-full has-[[data-variant=inset]]:bg-sidebar"><div class="group peer hidden text-sidebar-foreground md:block" data-state="collapsed" data-collapsible="offcanvas" data-variant="sidebar" data-side="left"><div class="relative w-(--sidebar-width) bg-transparent transition-[width] duration-200 ease-linear group-data-[collapsible=offcanvas]:w-0 group-data-[side=right]:rotate-180 group-data-[collapsible=icon]:w-(--sidebar-width-icon)"></div><div class="fixed inset-y-0 z-10 hidden h-svh w-(--sidebar-width) transition-[left,right,width] duration-200 ease-linear md:flex left-0 group-data-[collapsible=offcanvas]:left-[calc(var(--sidebar-width)*-1)] group-data-[collapsible=icon]:w-(--sidebar-width-icon) group-data-[side=left]:border-r group-data-[side=right]:border-l"><div data-sidebar="sidebar" class="flex h-full w-full flex-col bg-sidebar group-data-[variant=floating]:rounded-lg group-data-[variant=floating]:border group-data-[variant=floating]:border-sidebar-border group-data-[variant=floating]:shadow"><div data-sidebar="header" class="flex flex-col gap-2 p-2 px-5 py-0"><a class="block px-0 active" href="/" data-status="active" aria-current="page"><img src="/assets/phasezero-logo-BEy02M1R.png" alt="PhaseZero" class="h-48 w-auto max-w-[340px] -my-16 -ml-12" style="filter:invert(1) hue-rotate(180deg) brightness(2.2) saturate(1.2)"/></a></div><div data-sidebar="content" class="flex min-h-0 flex-1 flex-col gap-2 overflow-auto group-data-[collapsible=icon]:overflow-hidden"><div data-sidebar="group" class="relative flex w-full min-w-0 flex-col p-2"><div data-sidebar="group-content" class="w-full text-sm"><ul data-sidebar="menu" class="flex w-full min-w-0 flex-col gap-1"><li data-sidebar="menu-item" class="group/menu-item relative"><a data-sidebar="menu-button" data-size="default" data-active="true" class="peer/menu-button flex w-full items-center gap-2 overflow-hidden rounded-md p-2 text-left outline-none ring-sidebar-ring cursor-pointer transition-[width,height,padding] focus-visible:ring-2 active:bg-sidebar-accent active:text-sidebar-accent-foreground disabled:pointer-events-none disabled:opacity-50 disabled:cursor-not-allowed group-has-[[data-sidebar=menu-action]]/menu-item:pr-8 aria-disabled:pointer-events-none aria-disabled:opacity-50 data-[active=true]:bg-sidebar-accent data-[active=true]:font-medium data-[active=true]:text-sidebar-accent-foreground data-[state=open]:hover:bg-sidebar-accent data-[state=open]:hover:text-sidebar-accent-foreground group-data-[collapsible=icon]:!size-8 group-data-[collapsible=icon]:!p-2 [&amp;&gt;span:last-child]:truncate [&amp;&gt;svg]:size-4 [&amp;&gt;svg]:shrink-0 hover:bg-sidebar-accent hover:text-sidebar-accent-foreground h-8 text-sm relative active" href="/" data-status="active" aria-current="page"><span class="absolute right-0 top-1/2 h-5 w-[2px] -translate-y-1/2 bg-pz-accent"></span><svg xmlns="http://www.w3.org/2000/svg" width="15" height="15" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-crosshair text-pz-accent" aria-hidden="true"><circle cx="12" cy="12" r="10"></circle><line x1="22" x2="18" y1="12" y2="12"></line><line x1="6" x2="2" y1="12" y2="12"></line><line x1="12" x2="12" y1="6" y2="2"></line><line x1="12" x2="12" y1="22" y2="18"></line></svg><span class="text-[14px] font-light">Briefing Room</span></a></li><li data-sidebar="menu-item" class="group/menu-item relative"><a data-sidebar="menu-button" data-size="default" data-active="false" href="/opportunities" class="peer/menu-button flex w-full items-center gap-2 overflow-hidden rounded-md p-2 text-left outline-none ring-sidebar-ring cursor-pointer transition-[width,height,padding] focus-visible:ring-2 active:bg-sidebar-accent active:text-sidebar-accent-foreground disabled:pointer-events-none disabled:opacity-50 disabled:cursor-not-allowed group-has-[[data-sidebar=menu-action]]/menu
1-item:pr-8 aria-disabled:pointer-events-none aria-disabled:opacity-50 data-[active=true]:bg-sidebar-accent data-[active=true]:font-medium data-[active=true]:text-sidebar-accent-foreground data-[state=open]:hover:bg-sidebar-accent data-[state=open]:hover:text-sidebar-accent-foreground group-data-[collapsible=icon]:!size-8 group-data-[collapsible=icon]:!p-2 [&amp;&gt;span:last-child]:truncate [&amp;&gt;svg]:size-4 [&amp;&gt;svg]:shrink-0 hover:bg-sidebar-accent hover:text-sidebar-accent-foreground h-8 text-sm relative"><svg xmlns="http://www.w3.org/2000/svg" width="15" height="15" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-briefcase text-pz-muted" aria-hidden="true"><path d="M16 20V4a2 2 0 0 0-2-2h-4a2 2 0 0 0-2 2v16"></path><rect width="20" height="14" x="2" y="6" rx="2"></rect></svg><span class="text-[14px] font-light">Opportunities</span></a></li><li data-sidebar="menu-item" class="group/menu-item relative"><a data-sidebar="menu-button" data-size="default" data-active="false" href="/evidence" class="peer/menu-button flex w-full items-center gap-2 overflow-hidden rounded-md p-2 text-left outline-none ring-sidebar-ring cursor-pointer transition-[width,height,padding] focus-visible:ring-2 active:bg-sidebar-accent active:text-sidebar-accent-foreground disabled:pointer-events-none disabled:opacity-50 disabled:cursor-not-allowed group-has-[[data-sidebar=menu-action]]/menu-item:pr-8 aria-disabled:pointer-events-none aria-disabled:opacity-50 data-[active=true]:bg-sidebar-accent data-[active=true]:font-medium data-[active=true]:text-sidebar-accent-foreground data-[state=open]:hover:bg-sidebar-accent data-[state=open]:hover:text-sidebar-accent-foreground group-data-[collapsible=icon]:!size-8 group-data-[collapsible=icon]:!p-2 [&amp;&gt;span:last-child]:truncate [&amp;&gt;svg]:size-4 [&amp;&gt;svg]:shrink-0 hover:bg-sidebar-accent hover:text-sidebar-accent-foreground h-8 text-sm relative"><svg xmlns="http://www.w3.org/2000/svg" width="15" height="15" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-microscope text-pz-muted" aria-hidden="true"><path d="M6 18h8"></path><path d="M3 22h18"></path><path d="M14 22a7 7 0 1 0 0-14h-1"></path><path d="M9 14h2"></path><path d="M9 12a2 2 0 0 1-2-2V6h6v4a2 2 0 0 1-2 2Z"></path><path d="M12 6V3a1 1 0 0 0-1-1H9a1 1 0 0 0-1 1v3"></path></svg><span class="text-[14px] font-light">Evidence</span></a></li><li data-sidebar="menu-item" class="group/menu-item relative"><a data-sidebar="menu-button" data-size="default" data-active="false" href="/signals" class="peer/menu-button flex w-full items-center gap-2 overflow-hidden rounded-md p-2 text-left outline-none ring-sidebar-ring cursor-pointer transition-[width,height,padding] focus-visible:ring-2 active:bg-sidebar-accent active:text-sidebar-accent-foreground disabled:pointer-events-none disabled:opacity-50 disabled:cursor-not-allowed group-has-[[data-sidebar=menu-action]]/menu-item:pr-8 aria-disabled:pointer-events-none aria-disabled:opacity-50 data-[active=true]:bg-sidebar-accent data-[active=true]:font-medium data-[active=true]:text-sidebar-accent-foreground data-[state=open]:hover:bg-sidebar-accent data-[state=open]:hover:text-sidebar-accent-foreground group-data-[collapsible=icon]:!size-8 group-data-[collapsible=icon]:!p-2 [&amp;&gt;span:last-child]:truncate [&amp;&gt;svg]:size-4 [&amp;&gt;svg]:shrink-0 hover:bg-sidebar-accent hover:text-sidebar-accent-foreground h-8 text-sm relative"><svg xmlns="http://www.w3.org/2000/svg" width="15" height="15" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-chart-column text-pz-muted" aria-hidden="true"><path d="M3 3v16a2 2 0 0 0 2 2h16"></path><path d="M18 17V9"></path><path d="M13 17V5"></path><path d="M8 17v-3"></path></svg><span class="text-[14px] font-light">Signal Intel</span></a></li><li data-sidebar="menu-item" class="group/menu-item relative"><a data-sidebar="menu-button" data-size="default" data-active="false" href="/models" class="peer/menu-button flex w-full items-center gap-2 overflow-hidden rounded-md p-2 text-left outline-none ring-sidebar-ring cursor-pointer transition-[width,height,padding] focus-visible:ring-2 active:bg-sidebar-accent active:text-sidebar-accent-foreground disabled:pointer-events-none disabled:opacity-50 disabled:cursor-not-allowed group-has-[[data-sidebar=menu-action]]/menu
1-item:pr-8 aria-disabled:pointer-events-none aria-disabled:opacity-50 data-[active=true]:bg-sidebar-accent data-[active=true]:font-medium data-[active=true]:text-sidebar-accent-foreground data-[state=open]:hover:bg-sidebar-accent data-[state=open]:hover:text-sidebar-accent-foreground group-data-[collapsible=icon]:!size-8 group-data-[collapsible=icon]:!p-2 [&amp;&gt;span:last-child]:truncate [&amp;&gt;svg]:size-4 [&amp;&gt;svg]:shrink-0 hover:bg-sidebar-accent hover:text-sidebar-accent-foreground h-8 text-sm relative"><svg xmlns="http://www.w3.org/2000/svg" width="15" height="15" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-circle-dashed text-pz-muted" aria-hidden="true"><path d="M10.1 2.182a10 10 0 0 1 3.8 0"></path><path d="M13.9 21.818a10 10 0 0 1-3.8 0"></path><path d="M17.609 3.721a10 10 0 0 1 2.69 2.7"></path><path d="M2.182 13.9a10 10 0 0 1 0-3.8"></path><path d="M20.279 17.609a10 10 0 0 1-2.7 2.69"></path><path d="M21.818 10.1a10 10 0 0 1 0 3.8"></path><path d="M3.721 6.391a10 10 0 0 1 2.7-2.69"></path><path d="M6.391 20.279a10 10 0 0 1-2.69-2.7"></path></svg><span class="text-[14px] font-light">Models</span></a></li><li data-sidebar="menu-item" class="group/menu-item relative"><a data-sidebar="menu-button" data-size="default" data-active="false" href="/simulation" class="peer/menu-button flex w-full items-center gap-2 overflow-hidden rounded-md p-2 text-left outline-none ring-sidebar-ring cursor-pointer transition-[width,height,padding] focus-visible:ring-2 active:bg-sidebar-accent active:text-sidebar-accent-foreground disabled:pointer-events-none disabled:opacity-50 disabled:cursor-not-allowed group-has-[[data-sidebar=menu-action]]/menu-item:pr-8 aria-disabled:pointer-events-none aria-disabled:opacity-50 data-[active=true]:bg-sidebar-accent data-[active=true]:font-medium data-[active=true]:text-sidebar-accent-foreground data-[state=open]:hover:bg-sidebar-accent data-[state=open]:hover:text-sidebar-accent-foreground group-data-[collapsible=icon]:!size-8 group-data-[collapsible=icon]:!p-2 [&amp;&gt;span:last-child]:truncate [&amp;&gt;svg]:size-4 [&amp;&gt;svg]:shrink-0 hover:bg-sidebar-accent hover:text-sidebar-accent-foreground h-8 text-sm relative"><svg xmlns="http://www.w3.org/2000/svg" width="15" height="15" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-trending-up text-pz-muted" aria-hidden="true"><path d="M16 7h6v6"></path><path d="m22 7-8.5 8.5-5-5L2 17"></path></svg><span class="text-[14px] font-light">Decision Stress Test</span></a></li><li data-sidebar="menu-item" class="group/menu-item relative"><a data-sidebar="menu-button" data-size="default" data-active="false" href="/memos" class="peer/menu-button flex w-full items-center gap-2 overflow-hidden rounded-md p-2 text-left outline-none ring-sidebar-ring cursor-pointer transition-[width,height,padding] focus-visible:ring-2 active:bg-sidebar-accent active:text-sidebar-accent-foreground disabled:pointer-events-none disabled:opacity-50 disabled:cursor-not-allowed group-has-[[data-sidebar=menu-action]]/menu-item:pr-8 aria-disabled:pointer-events-none aria-disabled:opacity-50 data-[active=true]:bg-sidebar-accent data-[active=true]:font-medium data-[active=true]:text-sidebar-accent-foreground data-[state=open]:hover:bg-sidebar-accent data-[state=open]:hover:text-sidebar-accent-foreground group-data-[collapsible=icon]:!size-8 group-data-[collapsible=icon]:!p-2 [&amp;&gt;span:last-child]:truncate [&amp;&gt;svg]:size-4 [&amp;&gt;svg]:shrink-0 hover:bg-sidebar-accent hover:text-sidebar-accent-foreground h-8 text-sm relative"><svg xmlns="http://www.w3.org/2000/svg" width="15" height="15" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-book-text text-pz-muted" aria-hidden="true"><path d="M4 19.5v-15A2.5 2.5 0 0 1 6.5 2H19a1 1 0 0 1 1 1v18a1 1 0 0 1-1 1H6.5a1 1 0 0 1 0-5H20"></path><path d="M8 11h8"></path><path d="M8 7h6"></path></svg><span class="text-[14px] font-light">Memos</span></a></li><li data-sidebar="menu-item" class="group/menu-item relative"><a data-sidebar="menu-button" data-size="default" data-active="false" href="/settings" class="peer/menu-button flex w-full items-center gap-2 overflow-hidden rounded-md p-2 text-left outline-none ring-sidebar-ring cursor-pointer transition-[width,height,padding] focus-visible:ring-2 active:bg-sidebar-accent active:text-sidebar-accent-foreground disabled:pointer-events-none disabled:opacity-50 disabled:cursor-not-allowed group-has-[[data-sidebar=menu-action]]/menu
1-item:pr-8 aria-disabled:pointer-events-none aria-disabled:opacity-50 data-[active=true]:bg-sidebar-accent data-[active=true]:font-medium data-[active=true]:text-sidebar-accent-foreground data-[state=open]:hover:bg-sidebar-accent data-[state=open]:hover:text-sidebar-accent-foreground group-data-[collapsible=icon]:!size-8 group-data-[collapsible=icon]:!p-2 [&amp;&gt;span:last-child]:truncate [&amp;&gt;svg]:size-4 [&amp;&gt;svg]:shrink-0 hover:bg-sidebar-accent hover:text-sidebar-accent-foreground h-8 text-sm relative"><svg xmlns="http://www.w3.org/2000/svg" width="15" height="15" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-settings text-pz-muted" aria-hidden="true"><path d="M9.671 4.136a2.34 2.34 0 0 1 4.659 0 2.34 2.34 0 0 0 3.319 1.915 2.34 2.34 0 0 1 2.33 4.033 2.34 2.34 0 0 0 0 3.831 2.34 2.34 0 0 1-2.33 4.033 2.34 2.34 0 0 0-3.319 1.915 2.34 2.34 0 0 1-4.659 0 2.34 2.34 0 0 0-3.32-1.915 2.34 2.34 0 0 1-2.33-4.033 2.34 2.34 0 0 0 0-3.831A2.34 2.34 0 0 1 6.35 6.051a2.34 2.34 0 0 0 3.319-1.915"></path><circle cx="12" cy="12" r="3"></circle></svg><span class="text-[14px] font-light">Settings</span></a></li></ul></div></div></div><div data-sidebar="footer" class="flex flex-col gap-2 p-2 px-5 py-5"><div class="flex flex-col gap-3"><div class="border pz-border rounded-sm px-3 py-2.5 flex items-center gap-2"><span class="h-1.5 w-1.5 rounded-full bg-pz-accent pz-pulse"></span><div class="flex flex-col"><span class="text-[12px] text-sidebar-foreground">PhaseZero Research Desk</span><span class="font-mono-pz text-[9px] tracking-wider text-pz-accent">ONLINE</span></div></div><div class="flex items-center gap-2.5 px-1 py-1"><span class="h-7 w-7 rounded-full bg-[color:var(--pz-panel-alt)] border pz-border flex items-center justify-center font-mono-pz text-[10px] text-sidebar-foreground">BD</span><div class="flex flex-col items-start min-w-0"><span class="text-[12px] text-sidebar-foreground truncate">BD Opportunity Workspace</span><span class="text-[10px] text-sidebar-foreground/70 truncate">BD / Commercial Development</span></div><svg xmlns="http://www.w3.org/2000/svg" width="12" height="12" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-chevron-down ml-auto text-sidebar-foreground/60" aria-hidden="true"><path d="m6 9 6 6 6-6"></path></svg></div></div></div><button data-sidebar="rail" aria-label="Toggle Sidebar" tabindex="-1" title="Toggle Sidebar" class="absolute inset-y-0 z-20 hidden w-4 -translate-x-1/2 transition-all ease-linear after:absolute after:inset-y-0 after:left-1/2 after:w-[2px] hover:after:bg-sidebar-border group-data-[side=left]:-right-4 group-data-[side=right]:left-0 sm:flex [[data-side=left]_&amp;]:cursor-w-resize [[data-side=right]_&amp;]:cursor-e-resize [[data-side=left][data-state=collapsed]_&amp;]:cursor-e-resize [[data-side=right][data-state=collapsed]_&amp;]:cursor-w-resize group-data-[collapsible=offcanvas]:translate-x-0 group-data-[collapsible=offcanvas]:after:left-full group-data-[collapsible=offcanvas]:hover:bg-sidebar [[data-side=left][data-collapsible=offcanvas]_&amp;]:-right-2 [[data-side=right][data-collapsible=offcanvas]_&amp;]:-left-2"></button></div></div></div><main class="relative flex w-full flex-1 flex-col md:peer-data-[variant=inset]:m-2 md:peer-data-[state=collapsed]:peer-data-[variant=inset]:ml-2 md:peer-data-[variant=inset]:ml-0 md:peer-data-[variant=inset]:rounded-xl md:peer-data-[variant=inset]:shadow bg-pz-bg text-pz-text"><div class="min-h-screen bg-pz-bg text-pz-text flex flex-col"><div class="fixed top-4 left-4 z-50"><button class="inline-flex items-center justify-center gap-2 whitespace-nowrap text-sm font-medium cursor-pointer focus-visible:outline-none focus-visible:ring-1 focus-visible:ring-ring disabled:pointer-events-none disabled:opacity-50 disabled:cursor-not-allowed [&amp;_svg]:pointer-events-none [&amp;_svg]:size-4 [&amp;_svg]:shrink-0 hover:bg-accent h-9 w-9 rounded-sm border pz-border bg-pz-bg/80 backdrop-blur-sm text-pz-muted hover:text-pz-accent hover:border-pz-accent transition-colors" data-sidebar="trigger"><svg xmlns="http://www.w3.org/2000/svg" width="24" height="24" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-panel-left" aria-hidden="true"><rect width="18" height="18" x="3" y="3" rx="2"></rect><path d="M9 3v18"></path></svg><span class="sr-only">Toggle Sidebar</span></button></div><div class="relative h-screen w-full overflow-hidden bg-pz-bg" style="min-height:100svh"><svg class="animate-spotlight pointer-events-none absolute z-[1] h-[169%] w-[138%] lg:w-[84%] opacity-0 -top-40 left-0 md:left-20 md:-top-10" xmlns="http://www.w3.org/2000/svg" viewBox="0 0 3787 2842" fill="none">
1<g filter="url(#filter)"><ellipse cx="1924.71" cy="273.501" rx="1924.71" ry="273.501" transform="matrix(-0.822377 -0.568943 -0.568943 0.822377 3631.88 2291.09)" fill="#A8C979" fill-opacity="0.21"></ellipse></g><defs><filter id="filter" x="0.860352" y="0.838989" width="3785.16" height="2840.26" filterUnits="userSpaceOnUse" color-interpolation-filters="sRGB"><feFlood flood-opacity="0" result="BackgroundImageFix"></feFlood><feBlend mode="normal" in="SourceGraphic" in2="BackgroundImageFix" result="shape"></feBlend><feGaussianBlur stdDeviation="151" result="effect1_foregroundBlur_1065_8"></feGaussianBlur></filter></defs></svg><div class="pointer-events-none absolute inset-0 z-0" style="background:radial-gradient(ellipse 55% 45% at 72% 52%, rgba(168,201,121,0.07) 0%, transparent 70%)"></div><div class="relative z-10 flex h-full flex-col" style="opacity:1;transform:none"><div class="flex items-center justify-between px-8 lg:px-14 pt-6 pb-8 shrink-0"><div class="flex items-center" style="gap:14px"><div class="text-pz-accent">
1<svg width="41" height="37" viewBox="0 0 48 44" fill="none" aria-hidden="true"><path d="M5 40 L5 6" stroke="currentColor" stroke-width="3.8" stroke-linecap="square"></path><path d="M5 6 L26 6" stroke="currentColor" stroke-width="3.8" stroke-linecap="square"></path><path d="M26 6 L16 23" stroke="currentColor" stroke-width="3.8" stroke-linecap="square"></path><path d="M16 23 L5 23" stroke="currentColor" stroke-width="3.8" stroke-linecap="square"></path><path d="M14 13 L43 13" stroke="currentColor" stroke-width="3.8" stroke-linecap="square"></path><path d="M43 13 L14 40" stroke="currentColor" stroke-width="3.8" stroke-linecap="square"></path><path d="M14 40 L43 40" stroke="currentColor" stroke-width="3.8" stroke-linecap="square"></path></svg></div><div class="bg-pz-muted/30 shrink-0" style="width:1px;height:35px"></div><div class="flex flex-col justify-center"><div class="font-mono-pz leading-none" style="font-size:18px;letter-spacing:0.3em"><span class="text-pz-text font-medium">PHASE</span><span class="text-pz-accent font-medium">ZERO</span></div></div></div><a href="/opportunities" class="font-mono-pz text-[9px] tracking-[0.22em] uppercase text-pz-muted hover:text-pz-accent transition-colors">All Opportunities →</a></div><div class="flex-1 grid grid-cols-1 lg:grid-cols-2 gap-0 items-start px-8 lg:px-14"><div class="flex flex-col justify-start py-0"><div class="font-mono-pz text-[9.5px] tracking-[0.34em] uppercase text-pz-accent mb-5">ADC Opportunity Intelligence</div><h1 class="font-serif-display text-[50px] md:text-[68px] leading-[0.9] text-pz-text">Actionable ADC opportunities,<br/><em class="italic text-pz-accent font-normal">before consensus forms.</em></h1><p class="mt-6 max-w-md text-[14px] leading-relaxed text-pz-soft font-light">Eight autonomous agents monitor biomedical literature, clinical trials, and commercial signals — surfacing target-indication opportunities ranked by diligence relevance.</p><div class="mt-8 flex flex-wrap items-center gap-4"><a href="/opportunities/tf-adc" class="flex items-center gap-2.5 rounded-sm bg-pz-accent px-6 py-3 font-mono-pz text-[10px] tracking-[0.2em] uppercase text-[#080D0F] hover:bg-pz-accent/85 transition-colors">Top Opportunity <svg xmlns="http://www.w3.org/2000/svg" width="11" height="11" viewB
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1s Opportunity Brief</div><h2 class="mt-2 font-serif-display text-[28px] leading-tight text-pz-text">ADC opportunities, ranked by diligence signal.</h2></div><a href="/opportunities" class="hidden lg:flex items-center gap-1.5 font-mono-pz text-[9.5px] tracking-[0.2em] uppercase text-pz-muted hover:text-pz-accent transition-colors">All Opportunities <svg xmlns="http://www.w3.org/2000/svg" width="10" height="10" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-arrow-up-right" aria-hidden="true"><path d="M7 7h10v10"></path><path d="M7 17 17 7"></path></svg></a></div><div class="relative overflow-hidden" style="height:90px"><div class="absolute inset-0 pointer-events-none overflow-hidden"><svg class="w-full h-full" viewBox="0 0 696 316" fill="none" preserveAspectRatio="xMidYMid slice"><path d="M-380 -189C-380 -189 -312 216 152 343C616 470 684 875 684 875" stroke="#A8C979" stroke-width="0.4" stroke-opacity="0.12" opacity="0" pathLength="1" stroke-dashoffset="0" stroke-dasharray="0.3 1"></path><path d="M-385 -195C-385 -195 -317 210 157 337C621 464 689 869 689 869" stroke="#A8C979" stroke-width="0.42500000000000004" stroke-opacity="0.174" opacity="0" pathLength="1" stroke-dashoffset="0" stroke-dasharray="0.3 1"></path><path d="M-390 -201C-390 -201 -322 204 162 331C626 458 694 863 694 863" stroke="#A8C979" stroke-width="0.45" stroke-opacity="0.22799999999999998" opacity="0" pathLength="1" stroke-dashoffset="0" stroke-dasharray="0.3 1"></path><path d="M-395 -207C-395 -207 -327 198 167 325C631 452 699 857 699 857" stroke="#A8C979" stroke-width="0.47500000000000003" stroke-opacity="0.28200000000000003" opacity="0" pathLength="1" stroke-dashoffset="0" stroke-dasharray="0.3 1"></path><path d="M-400 -213C-400 -213 -332 192 172 319C636 446 704 851 704 851" stroke="#A8C979" stroke-width="0.5" stroke-opacity="0.33599999999999997" opacity="0" pathLength="1" stroke-dashoffset="0" stroke-dasharray="0.3 1"></path><path d="M-405 -219C-405 -219 -337 186 177 313C641 440 709 845 709 845" stroke="#A8C979" stroke-width="0.525" stroke-opacity="0.39" opacity="0" pathLength="1" stroke-dashoffset="0" stroke-dasharray="0.3 1"></path><path d="M-410 -225C-410 -225 -342 180 182 307C646 434 714 839 714 839" stroke="#A8C979" stroke-width="0.55" stroke-opacity="0.44399999999999995" opacity="0" pathLength="1" stroke-dashoffset="0" stroke-dasharray="0.3 1"></path><path d="M-415 -231C-415 -231 -347 174 187 301C651 428 719 833 719 833" stroke="#A8C979" stroke-width="0.5750000000000001" stroke-opacity="0.498" opacity="0" pathLength="1" stroke-dashoffset="0" stroke-dasharray="0.3 1"></path><path d="M-420 -237C-420 -237 -352 168 192 295C656 422 724 827 724 827" stroke="#A8C979" stroke-width="0.6000000000000001" stroke-opacity="0.552" opacity="0" pathLength="1" stroke-dashoffset="0" stroke-dasharray="0.3 1"></path><path d="M-425 -243C-425 -243 -357 162 197 289C661 416 729 821 729 821" stroke="#A8C979" stroke-width="0.625" stroke-opacity="0.606" opacity="0" pathLength="1" stroke-dashoffset="0" stroke-dasharray="0.3 1"></path><path d="M-430 -249C-430 -249 -362 156 202 283C666 410 734 815 734 815" stroke="#A8C979" stroke-width="0.65" stroke-opacity="0.66" opacity="0" pathLength="1" stroke-dashoffset="0" stroke-dasharray="0.3 1"></path><path d="M-435 -255C-435 -255 -367 150 207 277C671 404 739 809 739 809" stroke="#A8C979" stroke-width="0.675" stroke-opacity="0.714" opacity="0" pathLength="1" stroke-dashoffset="0" stroke-dasharray="0.3 1"></path><path d="M-440 -261C-440 -261 -372 144 212 271C676 398 744 803 744 803" stroke="#A8C979" stroke-width="0.7000000000000001" stroke-opacity="0.7679999999999998" opacity="0" pathLength="1" stroke-dashoffset="0" stroke-dasharray="0.3 1"></path><path d="M-445 -267C-445 -267 -377 138 217 265C681 392 749 797 749 797" stroke="#A8C979" stroke-width="0.7250000000000001" stroke-opacity="0.8219999999999998" opacity="0" pathLength="1" stroke-dashoffset="0" stroke-dasharray="0.3 1"></path><path d="M-450 -273C-450 -273 -382 132 222 259C686 386 754 791 754 791" stroke="#A8C979" stroke-width="0.75" stroke-opacity="0.85" opacity="0" pathLength="1" stroke-dashoffset="0" stroke-dasharray="0.3 1"></path><path d="M-455 -279C-455 -279 -387 126 227 253C691 380 759 785 759 785" stroke="#A8C979" stroke-width="0.775" stroke-opacity="0.85" opacity="0" pathLength="1" stroke-dashoffset="0" stroke-dasharray="0.3 1"></path>
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opacity="0" pathLength="1" stroke-dashoffset="0" stroke-dasharray="0.3 1"></path><path d="M-315 -345C-315 -345 -247 60 87 187C551 314 619 719 619 719" stroke="#A8C979" stroke-width="1.05" stroke-opacity="0.85" opacity="0" pathLength="1" stroke-dashoffset="0" stroke-dasharray="0.3 1"></path><path d="M-312.5 -351C-312.5 -351 -244.5 54 84.5 181C548.5 308 616.5 713 616.5 713" stroke="#A8C979" stroke-width="1.0750000000000002" stroke-opacity="0.85" opacity="0" pathLength="1" stroke-dashoffset="0" stroke-dasharray="0.3 1"></path><path d="M-310 -357C-310 -357 -242 48 82 175C546 302 614 707 614 707" stroke="#A8C979" stroke-width="1.1" stroke-opacity="0.85" opacity="0" pathLength="1" stroke-dashoffset="0" stroke-dasharray="0.3 1"></path><path d="M-307.5 -363C-307.5 -363 -239.5 42 79.5 169C543.5 296 611.5 701 611.5 701" stroke="#A8C979" stroke-width="1.125" stroke-opacity="0.85" opacity="0" pathLength="1" stroke-dashoffset="0" stroke-dasharray="0.3 1"></path><path d="M-305 -369C-305 -369 -237 36 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pathLength="1" stroke-dashoffset="0" stroke-dasharray="0.3 1"></path><path d="M-292.5 -399C-292.5 -399 -224.5 6 64.5 133C528.5 260 596.5 665 596.5 665" stroke="#A8C979" stroke-width="1.275" stroke-opacity="0.85" opacity="0" pathLength="1" stroke-dashoffset="0" stroke-dasharray="0.3 1"></path></svg></div></div><div class="relative z-10"><div class="h-[60rem] md:h-[80rem] flex items-center justify-center relative p-2 md:p-20"><div class="py-10 md:py-40 w-full relative" style="perspective:1000px"><div class="max-w-5xl mx-auto text-center" style="transform:none"><div class="mb-6"><div class="font-mono-pz text-[9.5px] tracking-[0.34em] uppercase text-pz-accent mb-4">Intelligence Platform</div><h2 class="font-serif-display text-[40px] md:text-[58px] leading-[0.92] text-pz-text">Signal to decision,<br/><em class="italic text-pz-accent font-normal">at machine speed.</em></h2><p class="mt-4 text-[13.5px] font-light text-pz-soft max-w-xl mx-auto">Eight autonomous agents monitor biomedical literature, clinical trials, regulatory precedent, and commercial data — surfacing ranked target-indication opportunities for BD review.</p></div></div><div class="max-w-5xl -mt-12 mx-auto h-[30rem] md:h-[40rem] w-full border-4 border-[#6C6C6C] p-2 md:p-6 bg-[#222222] rounded-[30px] shadow-2xl" style="box-shadow:0 0 #0000004d, 0 9px 20px #0000004a, 0 37px 37px #00000042, 0 84px 50px #00000026, 0 149px 60px #0000000a, 0 233px 65px #00000003;transform:scale(1.05) rotateX(20deg)"><div class="h-full w-full overflow-hidden rounded-2xl bg-gray-100 dark:bg-zinc-900 md:rounded-2xl md:p-4"><img src="/assets/phasezero-dashboard-vNEvhI2G.png" alt="PhaseZero analytics dashboard" class="mx-auto rounded-2xl object-cover h-full w-full object-top" draggable="false"/></div></div></div></div></div></div><section class="px-8 lg:px-14 pb-10"><div class="max-w-2xl"><div class="flex items-center gap-3 border rounded-sm px-4 py-3 transition-colors pz-border"><svg xmlns="http://www.w3.org/2000/svg" width="13" height="13" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-search text-pz-muted shrink-0" aria-hidden="true"><path d="m21 21-4.34-4.34"></path><circle cx="11" cy="11" r="8"></circle></svg><input type="text" placeholder="Search opportunities, targets, indications, companies, or mechanisms..." class="flex-1 bg-transparent text-[13px] font-light text-pz-text placeholder:text-pz-muted/50 outline-none" value=""/></div></div></section><section class="px-8 lg:px-14 pb-16 flex-1"><div class="mb-5 flex items-center gap-3 rounded-sm border pz-border bg-[rgba(168,201,121,0.04)] px-4 py-3"><span class="h-1.5 w-1.5 rounded-full bg-pz-accent shrink-0 pz-pulse"></span>
1<p class="text-[13px] text-pz-soft font-light flex-1">Click <span class="text-pz-accent font-medium">View Details</span> on any opportunity below to open the diligence workspace: signal intelligence, model inference, stress tests, and BD memo.</p></div><div class="flex flex-wrap items-baseline gap-x-4 gap-y-1"><span class="font-mono-pz text-[11px] tracking-[0.24em] uppercase text-pz-muted">Active Opportunities</span><span class="font-mono-pz text-[10px] tracking-[0.16em] uppercase text-pz-accent">4<!-- --> surfaced</span></div><div class="flex flex-col"><div data-orientation="horizontal" role="none" class="shrink-0 h-[1px] w-full bg-[rgba(168,201,121,0.12)]"></div><div class="group grid items-center gap-4 px-0 py-5 md:grid-cols-[1fr_2fr_auto]"><div class="flex items-center gap-3"><span class="flex h-14 w-14 shrink-0 items-center justify-center rounded-sm border" style="border-color:#A8C97933;color:#A8C979;background:#A8C9790D"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-flask-conical" aria-hidden="true"><path d="M14 2v6a2 2 0 0 0 .245.96l5.51 10.08A2 2 0 0 1 18 22H6a2 2 0 0 1-1.755-2.96l5.51-10.08A2 2 0 0 0 10 8V2"></path><path d="M6.453 15h11.094"></path><path d="M8.5 2h7"></path></svg></span><div class="flex flex-col gap-1 min-w-0"><div class="flex items-center gap-2"><span class="font-mono-pz text-[9px] tracking-[0.2em] uppercase" style="color:#A8C979">01</span><h3 class="font-serif-display text-[18px] leading-none text-pz-text group-hover:text-pz-accent transition-colors truncate">Tissue Factor ADC</h3></div><div class="flex flex-wrap items-center gap-2"><span class="font-mono-pz text-[10px] tracking-[0.14em] uppercase text-pz-muted">F3 / CD142<!-- --> · <!-- -->ADC</span><span class="inline-flex items-center gap-1 rounded-sm border px-2 py-0.5 font-mono-pz text-[8px] tracking-[0.12em] uppercase" style="border-color:#A8C97933;color:#A8C979"><span class="h-1 w-1 rounded-full shrink-0" style="background:#A8C979"></span>Advance to diligence memo</span></div></div></div><div><p class="text-[13px] leading-relaxed text-pz-soft font-light">New trial activity combined with high target expression data and significant commercial whitespace in the 2L+ setting.</p><div class="mt-2 flex items-center gap-1.5 font-mono-pz text-[10px] tracking-[0.12em] text-pz-muted"><svg xmlns="http://www.w3.org/2000/svg" width="10" height="10" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-trending-up text-pz-accent" aria-hidden="true"><path d="M16 7h6v6"></path><path d="m22 7-8.5 8.5-5-5L2 17"></path></svg><span class="text-pz-accent">+<!-- -->12<!-- --> signals</span><span>this week</span><span class="mx-2 opacity-30">·</span><span class="font-serif-display text-[16px] leading-none" style="color:#A8C979">70</span><span class="text-pz-muted">/ 100</span></div></div><a href="/opportunities/tf-adc" class="ml-auto flex items-center gap-2 rounded-sm border pz-border px-4 py-2 font-mono-pz text-[9.5px] tracking-[0.18em] uppercase text-pz-muted hover:border-pz-accent hover:text-pz-accent transition-colors whitespace-nowrap text-white bold">View Details <svg xmlns="http://www.w3.org/2000/svg" width="11" height="11" viewB
1ox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-arrow-right" aria-hidden="true"><path d="M5 12h14"></path><path d="m12 5 7 7-7 7"></path></svg></a></div><div data-orientation="horizontal" role="none" class="shrink-0 h-[1px] w-full bg-[rgba(168,201,121,0.12)]"></div><div class="group grid items-center gap-4 px-0 py-5 md:grid-cols-[1fr_2fr_auto]"><div class="flex items-center gap-3"><span class="flex h-14 w-14 shrink-0 items-center justify-center rounded-sm border" style="border-color:#D6B25A33;color:#D6B25A;background:#D6B25A0D"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-flask-conical" aria-hidden="true"><path d="M14 2v6a2 2 0 0 0 .245.96l5.51 10.08A2 2 0 0 1 18 22H6a2 2 0 0 1-1.755-2.96l5.51-10.08A2 2 0 0 0 10 8V2"></path><path d="M6.453 15h11.094"></path><path d="M8.5 2h7"></path></svg></span><div class="flex flex-col gap-1 min-w-0"><div class="flex items-center gap-2"><span class="font-mono-pz text-[9px] tracking-[0.2em] uppercase" style="color:#D6B25A">02</span><h3 class="font-serif-display text-[18px] leading-none text-pz-text group-hover:text-pz-accent transition-colors truncate">CLDN18.2 ADC</h3></div><div class="flex flex-wrap items-center gap-2"><span class="font-mono-pz text-[10px] tracking-[0.14em] uppercase text-pz-muted">CLDN18<!-- --> · <!-- -->ADC</span><span class="inline-flex items-center gap-1 rounded-sm border px-2 py-0.5 font-mono-pz text-[8px] tracking-[0.12em] uppercase" style="border-color:#D6B25A33;color:#D6B25A"><span class="h-1 w-1 rounded-full shrink-0" style="background:#D6B25A"></span>Monitor differentiation</span></div></div></div><div><p class="text-[13px] leading-relaxed text-pz-soft font-light">Strong target rationale and validated clinical precedent, but increasingly crowded competitive landscape demands a differentiation thesis.</p><div class="mt-2 flex items-center gap-1.5 font-mono-pz text-[10px] tracking-[0.12em] text-pz-muted"><svg xmlns="http://www.w3.org/2000/svg" width="10" height="10" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-trending-up text-pz-accent" aria-hidden="true"><path d="M16 7h6v6"></path><path d="m22 7-8.5 8.5-5-5L2 17"></path></svg><span class="text-pz-accent">+<!-- -->8<!-- --> signals</span><span>this week</span><span class="mx-2 opacity-30">·</span><span class="font-serif-display text-[16px] leading-none" style="color:#D6B25A">64</span><span class="text-pz-muted">/ 100</span></div></div><a href="/research?q=CLDN18.2+ADC+gastric+cancer" class="ml-auto flex items-center gap-2 rounded-sm border pz-border px-4 py-2 font-mono-pz text-[9.5px] tracking-[0.18em] uppercase text-pz-muted hover:border-pz-accent hover:text-pz-accent transition-colors whitespace-nowrap text-white bold">View Details <svg xmlns="http://www.w3.org/2000/svg" width="11" height="11" viewB
1ox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-arrow-right" aria-hidden="true"><path d="M5 12h14"></path><path d="m12 5 7 7-7 7"></path></svg></a></div><div data-orientation="horizontal" role="none" class="shrink-0 h-[1px] w-full bg-[rgba(168,201,121,0.12)]"></div><div class="group grid items-center gap-4 px-0 py-5 md:grid-cols-[1fr_2fr_auto]"><div class="flex items-center gap-3"><span class="flex h-14 w-14 shrink-0 items-center justify-center rounded-sm border" style="border-color:#D6B25A33;color:#D6B25A;background:#D6B25A0D"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-flask-conical" aria-hidden="true"><path d="M14 2v6a2 2 0 0 0 .245.96l5.51 10.08A2 2 0 0 1 18 22H6a2 2 0 0 1-1.755-2.96l5.51-10.08A2 2 0 0 0 10 8V2"></path><path d="M6.453 15h11.094"></path><path d="M8.5 2h7"></path></svg></span><div class="flex flex-col gap-1 min-w-0"><div class="flex items-center gap-2"><span class="font-mono-pz text-[9px] tracking-[0.2em] uppercase" style="color:#D6B25A">03</span><h3 class="font-serif-display text-[18px] leading-none text-pz-text group-hover:text-pz-accent transition-colors truncate">Nectin-4 ADC Expansion</h3></div><div class="flex flex-wrap items-center gap-2"><span class="font-mono-pz text-[10px] tracking-[0.14em] uppercase text-pz-muted">NECTIN4<!-- --> · <!-- -->ADC</span><span class="inline-flex items-center gap-1 rounded-sm border px-2 py-0.5 font-mono-pz text-[8px] tracking-[0.12em] uppercase" style="border-color:#D6B25A33;color:#D6B25A"><span class="h-1 w-1 rounded-full shrink-0" style="background:#D6B25A"></span>Stress-test indication expansion</span></div></div></div><div><p class="text-[13px] leading-relaxed text-pz-soft font-light">Label expansion potential across multiple solid tumor types, backed by known ADC structural precedent from the approved urothelial program.</p><div class="mt-2 flex items-center gap-1.5 font-mono-pz text-[10px] tracking-[0.12em] text-pz-muted"><svg xmlns="http://www.w3.org/2000/svg" width="10" height="10" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-trending-up text-pz-accent" aria-hidden="true"><path d="M16 7h6v6"></path><path d="m22 7-8.5 8.5-5-5L2 17"></path></svg><span class="text-pz-accent">+<!-- -->6<!-- --> signals</span><span>this week</span><span class="mx-2 opacity-30">·</span><span class="font-serif-display text-[16px] leading-none" style="color:#D6B25A">62</span><span class="text-pz-muted">/ 100</span></div></div><a href="/opportunities/nectin4-adc" class="ml-auto flex items-center gap-2 rounded-sm border pz-border px-4 py-2 font-mono-pz text-[9.5px] tracking-[0.18em] uppercase text-pz-muted hover:border-pz-accent hover:text-pz-accent transition-colors whitespace-nowrap text-white bold">View Details <svg xmlns="http://www.w3.org/2000/svg" width="11" height="11" viewB
1ox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-arrow-right" aria-hidden="true"><path d="M5 12h14"></path><path d="m12 5 7 7-7 7"></path></svg></a></div><div data-orientation="horizontal" role="none" class="shrink-0 h-[1px] w-full bg-[rgba(168,201,121,0.12)]"></div><div class="group grid items-center gap-4 px-0 py-5 md:grid-cols-[1fr_2fr_auto]"><div class="flex items-center gap-3"><span class="flex h-14 w-14 shrink-0 items-center justify-center rounded-sm border" style="border-color:#C98A8A33;color:#C98A8A;background:#C98A8A0D"><svg xmlns="http://www.w3.org/2000/svg" width="20" height="20" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-flask-conical" aria-hidden="true"><path d="M14 2v6a2 2 0 0 0 .245.96l5.51 10.08A2 2 0 0 1 18 22H6a2 2 0 0 1-1.755-2.96l5.51-10.08A2 2 0 0 0 10 8V2"></path><path d="M6.453 15h11.094"></path><path d="M8.5 2h7"></path></svg></span><div class="flex flex-col gap-1 min-w-0"><div class="flex items-center gap-2"><span class="font-mono-pz text-[9px] tracking-[0.2em] uppercase" style="color:#C98A8A">04</span><h3 class="font-serif-display text-[18px] leading-none text-pz-text group-hover:text-pz-accent transition-colors truncate">B7-H4 ADC</h3></div><div class="flex flex-wrap items-center gap-2"><span class="font-mono-pz text-[10px] tracking-[0.14em] uppercase text-pz-muted">VTCN1<!-- --> · <!-- -->ADC</span><span class="inline-flex items-center gap-1 rounded-sm border px-2 py-0.5 font-mono-pz text-[8px] tracking-[0.12em] uppercase" style="border-color:#C98A8A33;color:#C98A8A"><span class="h-1 w-1 rounded-full shrink-0" style="background:#C98A8A"></span>Needs de-risking</span></div></div></div><div><p class="text-[13px] leading-relaxed text-pz-soft font-light">Emerging target interest with early-phase clinical signals, but failure-risk flags from hematologic toxicity precedents require de-risking before advancement.</p><div class="mt-2 flex items-center gap-1.5 font-mono-pz text-[10px] tracking-[0.12em] text-pz-muted"><svg xmlns="http://www.w3.org/2000/svg" width="10" height="10" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-trending-up text-pz-accent" aria-hidden="true"><path d="M16 7h6v6"></path><path d="m22 7-8.5 8.5-5-5L2 17"></path></svg><span class="text-pz-accent">+<!-- -->4<!-- --> signals</span><span>this week</span><span class="mx-2 opacity-30">·</span><span class="font-serif-display text-[16px] leading-none" style="color:#C98A8A">52</span><span class="text-pz-muted">/ 100</span></div></div><a href="/opportunities/b7h4-adc" class="ml-auto flex items-center gap-2 rounded-sm border pz-border px-4 py-2 font-mono-pz text-[9.5px] tracking-[0.18em] uppercase text-pz-muted hover:border-pz-accent hover:text-pz-accent transition-colors whitespace-nowrap text-white bold">View Details <svg xmlns="http://www.w3.org/2000/svg" width="11" height="11" viewB
1ox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-arrow-right" aria-hidden="true"><path d="M5 12h14"></path><path d="m12 5 7 7-7 7"></path></svg></a></div><div data-orientation="horizontal" role="none" class="shrink-0 h-[1px] w-full bg-[rgba(168,201,121,0.12)]"></div></div></section><section class="px-8 lg:px-14 border-t pz-border py-12"><div class="grid grid-cols-1 lg:grid-cols-[1fr_260px] gap-10 lg:gap-16 items-start"><div><div class="flex items-center gap-3 mb-2"><span class="font-mono-pz text-[10px] tracking-[0.24em] uppercase text-pz-muted">Intelligence Feed</span><span class="h-1.5 w-1.5 rounded-full bg-pz-accent pz-pulse"></span><span class="font-mono-pz text-[9px] tracking-[0.16em] uppercase text-pz-accent">Live</span></div><ul><li class="border-t pz-border py-3.5 flex items-start gap-3"><span class="mt-[5px] h-1.5 w-1.5 rounded-full shrink-0" style="background:#A8C979"></span><div class="flex-1 min-w-0 text-[13px] text-pz-soft font-light leading-snug"><span class="text-pz-text">Trial Agent</span> <!-- -->found 2 new ADC studies in cervical cancer</div><span class="font-mono-pz text-[9px] tracking-[0.12em] text-pz-muted shrink-0 pt-0.5">4m ago</span></li><li class="border-t pz-border py-3.5 flex items-start gap-3"><span class="mt-[5px] h-1.5 w-1.5 rounded-full shrink-0" style="background:#A8C979"></span><div class="flex-1 min-w-0 text-[13px] text-pz-soft font-light leading-snug"><span class="text-pz-text">Literature Agent</span> <!-- -->extracted 14 target-expression signals across 3 candidates</div><span class="font-mono-pz text-[9px] tracking-[0.12em] text-pz-muted shrink-0 pt-0.5">12m ago</span></li><li class="border-t pz-border py-3.5 flex items-start gap-3"><span class="mt-[5px] h-1.5 w-1.5 rounded-full shrink-0" style="background:#D6B25A"></span><div class="flex-1 min-w-0 text-[13px] text-pz-soft font-light leading-snug"><span class="text-pz-text">Failure Agent</span> <!-- -->flagged hematologic toxicity precedent in B7-H4 program</div><span class="font-mono-pz text-[9px] tracking-[0.12em] text-pz-muted shrink-0 pt-0.5">28m ago</span></li><li class="border-t pz-border py-3.5 flex items-start gap-3"><span class="mt-[5px] h-1.5 w-1.5 rounded-full shrink-0" style="background:#A8C979"></span><div class="flex-1 min-w-0 text-[13px] text-pz-soft font-light leading-snug"><span class="text-pz-text">Commercial Agent</span> <!-- -->identified 2L+ cervical whitespace in competitive landscape</div><span class="font-mono-pz text-[9px] tracking-[0.12em] text-pz-muted shrink-0 pt-0.5">41m ago</span></li><li class="border-t pz-border py-3.5 flex items-start gap-3"><span class="mt-[5px] h-1.5 w-1.5 rounded-full shrink-0" style="background:#A8C979"></span><div class="flex-1 min-w-0 text-[13px] text-pz-soft font-light leading-snug"><span class="text-pz-text">Structure Agent</span> <!-- -->found predicted AlphaFold structure candidate for VTCN1</div><span class="font-mono-pz text-[9px] tracking-[0.12em] text-pz-muted shrink-0 pt-0.5">1h ago</span></li></ul></div><div class="border-t pz-border pt-4 lg:border-t-0 lg:pt-0 lg:border-l lg:pl-10"><div class="font-mono-pz text-[10px] tracking-[0.24em] uppercase text-pz-muted mb-5">System Status</div><div class="flex items-center gap-2 mb-6"><span class="h-1.5 w-1.5 rounded-full bg-pz-accent pz-pulse"></span><span class="font-mono-pz text-[9px] tracking-[0.16em] uppercase text-pz-accent">All systems operational</span></div><div class="flex flex-col gap-0"><div class="border-t pz-border py-3.5"><div class="font-serif-display text-[30px] leading-none text-pz-text">128</div><div class="mt-1 font-mono-pz text-[9px] tracking-[0.16em] uppercase text-pz-muted">signals monitored</div></div><div class="border-t pz-border py-3.5"><div class="font-serif-display text-[30px] leading-none text-pz-text">8</div><div class="mt-1 font-mono-pz text-[9px] tracking-[0.16em] uppercase text-pz-muted">agents 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