1<!DOCTYPE html><html lang="en"><head><meta charSet="utf-8"/><meta name="viewport" content="width=device-width, initial-scale=1"/><link rel="preload" as="image" href="/assets/phasezero-logo-BEy02M1R.png"/><link rel="stylesheet" href="/assets/styles-nHABoWFz.css" data-precedence="default"/><title>PhaseZero â Therapeutic Intelligence OS</title><meta name="description" content="AI-native scientific diligence cockpit for ADC commercial development. Find therapeutic alpha before consensus forms."/><meta name="author" content="PhaseZero"/><meta property="og:title" content="PhaseZero â Therapeutic Intelligence OS"/><meta property="og:description" content="AI-native scientific diligence cockpit for ADC commercial development."/><meta property="og:type" content="website"/><meta name="twitter:card" content="summary"/><meta name="twitter:site" content="@Lovable"/><link rel="modulepreload" href="/assets/index-iAVlVxvB.js"/><link rel="modulepreload" href="/assets/signals-C8rTdlUP.js"/><link rel="modulepreload" href="/assets/primitives-B-PYiOq8.js"/><link rel="modulepreload" href="/assets/CandidatePicker-D8_1LnRX.js"/><link rel="modulepreload" href="/assets/usePhaseZero-DYXhC0Em.js"/><link rel="modulepreload" href="/assets/Sidebar-BstMbomz.js"/></head><body><!--$--><div style="--sidebar-width:16rem;--sidebar-width-icon:3rem" class="group/sidebar-wrapper flex min-h-svh w-full has-[[data-variant=inset]]:bg-sidebar"><div class="group peer hidden text-sidebar-foreground md:block" data-state="expanded" data-collapsible="" data-variant="sidebar" data-side="left"><div class="relative w-(--sidebar-width) bg-transparent transition-[width] duration-200 ease-linear group-data-[collapsible=offcanvas]:w-0 group-data-[side=right]:rotate-180 group-data-[collapsible=icon]:w-(--sidebar-width-icon)"></div><div class="fixed inset-y-0 z-10 hidden h-svh w-(--sidebar-width) transition-[left,right,width] duration-200 ease-linear md:flex left-0 group-data-[collapsible=offcanvas]:left-[calc(var(--sidebar-width)*-1)] group-data-[collapsible=icon]:w-(--sidebar-width-icon) group-data-[side=left]:border-r group-data-[side=right]:border-l"><div data-sidebar="sidebar" class="flex h-full w-full flex-col bg-sidebar group-data-[variant=floating]:rounded-lg group-data-[variant=floating]:border group-data-[variant=floating]:border-sidebar-border group-data-[variant=floating]:shadow"><div data-sidebar="header" class="flex flex-col gap-2 p-2 px-5 py-0"><a href="/" class="block px-0"><img src="/assets/phasezero-logo-BEy02M1R.png" alt="PhaseZero" class="h-48 w-auto max-w-[340px] -my-16 -ml-12" style="filter:invert(1) hue-rotate(180deg) brightness(2.2) saturate(1.2)"/></a></div><div data-sidebar="content" class="flex min-h-0 flex-1 flex-col gap-2 overflow-auto group-data-[collapsible=icon]:overflow-hidden"><div data-sidebar="group" class="relative flex w-full min-w-0 flex-col p-2"><div data-sidebar="group-content" class="w-full text-sm"><ul data-sidebar="menu" class="flex w-full min-w-0 flex-col gap-1"><li data-sidebar="menu-item" class="group/menu-item relative"><a data-sidebar="menu-button" data-size="default" data-active="false" href="/" class="peer/menu-button flex w-full items-center gap-2 overflow-hidden rounded-md p-2 text-left outline-none ring-sidebar-ring cursor-pointer transition-[width,height,padding] focus-visible:ring-2 active:bg-sidebar-accent active:text-sidebar-accent-foreground disabled:pointer-events-none disabled:opacity-50 disabled:cursor-not-allowed group-has-[[data-sidebar=menu-action]]/menu-item:pr-8 aria-disabled:pointer-events-none aria-disabled:opacity-50 data-[active=true]:bg-sidebar-accent data-[active=true]:font-medium data-[active=true]:text-sidebar-accent-foreground data-[state=open]:hover:bg-sidebar-accent data-[state=open]:hover:text-sidebar-accent-foreground group-data-[collapsible=icon]:!size-8 group-data-[collapsible=icon]:!p-2 [&>span:last-child]:truncate [&>svg]:size-4 [&>svg]:shrink-0 hover:bg-sidebar-accent hover:text-sidebar-accent-foreground h-8 text-sm relative"><svg xmlns="http://www.w3.org/2000/svg" width="15" height="15" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-crosshair text-pz-muted" aria-hidden="true"><circle cx="12" cy="12" r="10"></circle><line x1="22" x2="18" y1="12" y2="12"></line><line x1="6" x2="2" y1="12" y2="12"></line><line x1="12" x2="12" y1="6" y2="2"></line><line x1="12" x2="12" y1="22" y2="18"></line></svg><span class="text-[14px] font-light">Briefing Room</span></a></li><li data-sidebar="menu-item" class="group/menu-item relative"><a data-sidebar="menu-button" data-size="default" data-active="false" href="/opportunities" class="peer/menu-button flex w-full items-center gap-2 overflow-hidden rounded-md p-2 text-left outline-none ring-sidebar-ring cursor-pointer transition-[width,height,padding] focus-visible:ring-2 active:bg-sidebar-accent active:text-sidebar-accent-foreground disabled:pointer-events-none disabled:opacity-50 disabled:cursor-not-allowed group-has-[[data-sidebar=menu-action]]/menu
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1-2.33-4.033 2.34 2.34 0 0 0 0-3.831A2.34 2.34 0 0 1 6.35 6.051a2.34 2.34 0 0 0 3.319-1.915"></path><circle cx="12" cy="12" r="3"></circle></svg><span class="text-[14px] font-light">Settings</span></a></li></ul></div></div></div><div data-sidebar="footer" class="flex flex-col gap-2 p-2 px-5 py-5"><div class="flex flex-col gap-3"><div class="border pz-border rounded-sm px-3 py-2.5 flex items-center gap-2"><span class="h-1.5 w-1.5 rounded-full bg-pz-accent pz-pulse"></span><div class="flex flex-col"><span class="text-[12px] text-sidebar-foreground">PhaseZero Research Desk</span><span class="font-mono-pz text-[9px] tracking-wider text-pz-accent">ONLINE</span></div></div><div class="flex items-center gap-2.5 px-1 py-1"><span class="h-7 w-7 rounded-full bg-[color:var(--pz-panel-alt)] border pz-border flex items-center justify-center font-mono-pz text-[10px] text-sidebar-foreground">BD</span><div class="flex flex-col items-start min-w-0"><span class="text-[12px] text-sidebar-foreground truncate">BD Opportunity Workspace</span><span class="text-[10px] text-sidebar-foreground/70 truncate">BD / Commercial Development</span></div><svg xmlns="http://www.w3.org/2000/svg" width="12" height="12" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-chevron-down ml-auto text-sidebar-foreground/60" aria-hidden="true"><path d="m6 9 6 6 6-6"></path></svg></div></div></div><button data-sidebar="rail" aria-label="Toggle Sidebar" tabindex="-1" title="Toggle Sidebar" class="absolute inset-y-0 z-20 hidden w-4 -translate-x-1/2 transition-all ease-linear after:absolute after:inset-y-0 after:left-1/2 after:w-[2px] hover:after:bg-sidebar-border group-data-[side=left]:-right-4 group-data-[side=right]:left-0 sm:flex [[data-side=left]_&]:cursor-w-resize [[data-side=right]_&]:cursor-e-resize [[data-side=left][data-state=collapsed]_&]:cursor-e-resize [[data-side=right][data-state=collapsed]_&]:cursor-w-resize 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[&_svg]:size-4 [&_svg]:shrink-0 hover:bg-accent h-7 w-7 text-pz-muted hover:text-pz-text" data-sidebar="trigger"><svg xmlns="http://www.w3.org/2000/svg" width="24" height="24" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-panel-left" aria-hidden="true"><rect width="18" height="18" x="3" y="3" rx="2"></rect><path d="M9 3v18"></path></svg><span class="sr-only">Toggle Sidebar</span></button><div class="flex items-center gap-2"><span class="h-1.5 w-1.5 rounded-full bg-pz-accent pz-pulse"></span><span class="font-mono-pz text-[10px] tracking-[0.22em] uppercase text-pz-accent">Syncing Live Data</span></div></div><div class="flex items-center gap-2.5 min-w-[280px] max-w-[420px] w-full border-b pz-border pb-1.5"><svg xmlns="http://www.w3.org/2000/svg" width="13" height="13" viewBox="0 0 24 24" fill="none" stroke="currentColor" stroke-width="2" stroke-linecap="round" stroke-linejoin="round" class="lucide lucide-search text-pz-muted" aria-hidden="true"><path d="m21 21-4.34-4.34"></path><circle cx="11" cy="11" r="8"></circle></svg><input type="text" placeholder="Search targets, modalities, or dataâ¦" class="bg-transparent text-[12.5px] text-pz-soft placeholder:text-pz-muted outline-none w-full font-light"/></div></div><main class="flex-1 px-8 lg:px-12 pt-8 pb-12" style="opacity:0;transform:translateY(18px)"><header class="mb-6"><div class="font-mono-pz text-[10px] tracking-[0.28em] uppercase text-pz-accent">Signal Intelligence Layer</div><h1 class="mt-2 font-serif-display text-[40px] leading-none text-pz-text font-normal">Signal Intelligence</h1><p class="mt-3 text-[13px] text-pz-soft font-light max-w-2xl">PhaseZero does not just scrape more data. It turns noisy public evidence into weighted signal events, then infers whether an ADC opportunity is strengthening, saturating, contradicting itself, or drifting toward failure.</p></header><div class="grid grid-cols-1 xl:grid-cols-3 gap-4 mb-6">
1<section class="pz-panel rounded-sm p-6 p-5"><div class="font-mono-pz text-[10px] tracking-[0.22em] uppercase text-pz-muted">What You Are Looking At</div><p class="mt-3 text-[12.5px] leading-snug text-pz-soft font-light">A deterministic signal ledger for one target-indication opportunity, built from literature, trial, regulatory, commercial, and biology-facing evidence events.</p></section><section class="pz-panel rounded-sm p-6 p-5"><div class="font-mono-pz text-[10px] tracking-[0.22em] uppercase text-pz-muted">Why It Matters</div><p class="mt-3 text-[12.5px] leading-snug text-pz-soft font-light">The layer separates hidden alpha from crowded consensus, noisy signals, contradiction burden, and missing-data burden.</p></section><section class="pz-panel rounded-sm p-6 p-5"><div class="font-mono-pz text-[10px] tracking-[0.22em] uppercase text-pz-muted">What To Do Next</div><p class="mt-3 text-[12.5px] leading-snug text-pz-soft font-light">Pick an opportunity, inspect its signal regime, then use the disputed claim and diligence questions to guide expert review.</p></section></div><div class="flex items-center gap-3 py-10 justify-center"><span class="h-5 w-5 rounded-full border border-[rgba(168,201,121,0.35)] border-t-pz-accent animate-spin"></span><span class="font-mono-pz text-[10px] tracking-[0.22em] uppercase text-pz-muted">Loading candidates</span></div></main></main></div>
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Line numbers count LF bytes from the start of the resource, as the search results do. Vendor segments are library code the classifier recognised; they are stored but not indexed. Bytes are shown as Latin1 characters, one per byte.