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187 188</head> 189 190<body id="onecolumn"> 191 <div id="container"> 192 <div class="wrapper"> 193 <div id="header"> 194 <div class="wrapper"> 195 <h1 id="page-title"><div id='g_title'><p>David J Reiss, PhD </p></div></h1> 196 <div style="clear: both;"></div> 197 <!--<p class="description"><div id='g_description'><p>For a little (not much) more about me, visit <a href="http://depts.washington.edu/astron/profile/reiss-david">my UW profile</a>.</p></div></p>--> 198 <div style="clear: both"></div> 199 </div> 200 </div> 201 <!-- /editable --><!-- /wrapper --><!-- /header --> 202 <div id="main-content"> 203 204 <div class="wrapper"> 205 <div class="content-item "><div id='g_body'> 206 <p>I am currently a Senior Image AI/ML Scientist at a large BioPharma company. 207 Among other things, I primarily research computational methods for analyzing large cellular microscopy images to discover novel drug targets, and to understand and improve patient responses in clinical trials. This imaging research includes deep learning, statistical analysis, feature extraction, spatial and community/neighborhood analysis, and integration with biomarker, genomic, transcriptomic, or clinical data.</p> 208 <p>Previously, I was a Data Management Research Scientist for the <a href="http://lsst.org">Large Synoptic Survey Telescope</a>, at the <a href='http://lsst.astro.washington.edu'>University of Washington dept. of Astronomy</a>, where 209 I researched algorithms and developed software for image subtraction and transient detection, with interest in all kinds of transients, particularly supernovae.</p> 210 <p>Prior to that, I was a <a href="http://www.systemsbiology.org/David-Reiss">Senior Computational Systems Biology Research Scientist</a> at the <a href="http://systemsbiology.org">Institute for Systems Biology</a>, where I developed computational algorithms and methods for modeling systems-level biological data.</p> 211 212<p>For my PhD, I developed and applied methods for detection of faint signals in astronomical images, and applied them to discover nearby and distant supernovae. This research contributed to the discovery of the accelerating expansion of the universe (as part of the High-Z Supernova Search Team), a discovery which received the <a href="https://www.nobelprize.org/prizes/physics/2011/press-release/">Nobel Prize in Physics (2011)</a>, the <a href="https://gruber.yale.edu/prize/2007-gruber-cosmology-prize">Gruber Cosmology Prize (2007)</a>, and the <a href="https://breakthroughprize.org/News/21">Breakthrough Prize in Fundamental Physics (2015)</a>.</p> 213 <ul> 214 <li><b>Publications:</b> <a href="http://adsabs.harvard.edu/cgi-bin/nph-abs_connect?db_key=AST&db_key=PRE&qform=AST&arxiv_sel=astro-ph&arxiv_sel=cond-mat&arxiv_sel=cs&arxiv_sel=gr-qc&arxiv_sel=hep-ex&arxiv_sel=hep-lat&arxiv_sel=hep-ph&arxiv_sel=hep-th&arxiv_sel=math&arxiv_sel=math-ph&arxiv_sel=nlin&arxiv_sel=nucl-ex&arxiv_sel=nucl-th&arxiv_sel=physics&arxiv_sel=quant-ph&arxiv_sel=q-bio&sim_query=YES&ned_query=YES&aut_req=YES&aut_logic=SIMPLE&obj_logic=OR&author=reiss%2C+D%0D%0A-helbert&object=&start_mon=&start_year=&end_mon=&end_year=&ttl_logic=OR&title=&txt_req=YES&txt_logic=OR&text=supernova+microlensing+cygni&nr_to_return=200&start_nr=1&jou_pick=ALL&ref_stems=&data_and=ALL&group_and=ALL&start_entry_day=&start_entry_mon=&start_entry_year=&end_entry_day=&end_entry_mon=&end_entry_year=&min_score=&sort=NDATE&data_type=SHORT&aut_syn=YES&ttl_syn=YES&txt_syn=YES&aut_wt=1.0&obj_wt=1.0&ttl_wt=0.3&txt_wt=3.0&aut_wgt=YES&obj_wgt=YES&ttl_wgt=YES&txt_wgt=YES&ttl_sco=YES&txt_sco=YES&version=1">Astronomy</a> 215 and <a href="https://pubmed.ncbi.nlm.nih.gov/?term=reiss+d+and+%28%22systems+biology%22+OR+schwikowski+OR+bonneau+OR+baliga+OR+stuetzle+OR+gandhi+OR+danziger+OR+ratushnyy%29&sort=date">Biology</a> publications; or <a href="https://scholar.google.com/citations?user=fUmbrcoAAAAJ">all publications according to Google</a><br></li> 216 <li><a href="thesis_david_j_reiss.pdf">PhD Thesis</a>: <font size="2">"The Rate of Supernovae in the Nearby and Distant Universe"</font></li> 217 </ul> 218 <ul><li><a href="http://github.com/djreiss">Public Github profile</a></li></ul> 219 <ul> 220 <li>Some of my published computational biology software:</li> 221 <ul> 222 <li><a href="netmotsa-1.9979.tar.gz">Netmotsa</a> - Network-oriented Gibbs sampling for motif detection<br></li> 223 <!--<li><a href="http://labs.systemsbiology.net/galitski/hepc">Hepatitis-C project</a> - Identifying pathways putatively active in disease infection <br></li>--> 224 <li><a href="http://djreiss.github.io/cMonkey/">cMonkey</a> - Biclustering of mRNA expression data, constrained by biological priors (interaction networks, DNA sequence motifs, etc.)</li> 225 <li><a href="http://github.com/djreiss/cMonkeyNwInf/">
225Inferelator</a> - Inference of gene regulatory networks (in conjunction with <a href="http://labs.systemsbiology.net/baliga/cmonkey/">cMonkey</a>)</li> 226 <li><a href="http://github.com/djreiss/MeDiChI">MeDiChI</a> - Model-based deconvolution of genome wide DNA binding (ChIP-chip) data</li> 227 <li><a href="http://github.com/djreiss/tilingArraySeg">tilingArraySeg</a> - Multivariate segmentation of high-resolution tiling microarray data 228 </ul></ul> 229 <ul><li>Projects written "<a href="http://github.com/djreiss">for fun</a>":</li> 230 <ul> 231 <li><a href="asteroids">3-D Javascript asteroids game</a></li> 232 <!--<li><a href="old_pages">Old web pages and projects</a> (some links may not work)</a>--> 233 </ul></ul> 234 </div></div> 235 <div style="clear: both"></div> 236 </div> 237 </div> 238 <!-- /wrapper --><!-- /main-content --> 239 <div id="footer"><div class="wrapper"> 240 <hr /> 241 <p><div id='g_footer'> 242<p>Last updated Apr., 2024</p> 243
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