1<!DOCTYPE html PUBLIC "-//W3C//DTD XHTML 1.0 Strict//EN" "http://www.w3.org/TR/xhtml1/DTD/xhtml1-strict.dtd"> 2<html xmlns="http://www.w3.org/1999/xhtml" lang="en" xml:lang="en"> 3<head> 4 <meta http-equiv="content-type" content="text/html; charset=utf-8" /> 5 <meta name="description" content="Schulz Lab" /> 6 <meta name="keywords" content="Computation epigenomics, data science, bioinformatics" /> 7 <meta name="author" content="Marcel Schulz" /> 8 <link rel="stylesheet" type="text/css" href="variant-trio.css" title="Variant Trio" media="screen,projection" /> 9 <title>Schulz Lab</title> 10</head> 11 12<body> 13<div id="wrap"> 14 <h1><a href="index.html">Schulz Lab</a></h1> 15 <div id="slogan"> 16 <h3> Institute for Computational Genomic Medicine</h3> </div> 17 <div id="topmenu"> 18 <p> 19 <strong class="hide">Main menu:</strong> 20 <a class="active" href="index.html">Home</a><span class="hide"> | </span> 21 <a href="team.html">Team</a><span class="hide"> | </span> 22 <a href="projects.html">Projects</a><span class="hide"> | </span> 23 <!--<a href="projects.html">Software</a><span class="hide"> | </span> --> 24 <a href="publications.html">Publications</a><span class="hide"> | </span> 25 <a href="teaching.html">Teach</a><span class="hide"> | </span> 26 <a href="software.html">Tools</a><span class="hide"> | </span> 27 <a href="jobs.html">Jobs</a><span class="hide"> | </span> 28 </p> 29 </div> 30 31 <div id="sidebar"> 32 33 <img src="img/MC_Logo_Final2_NoBG.png" width="170" height="215" alt="Logo" /> 34 35 36 37 <ul class="sidemenu"> 38 <h2>News</h2> 39 <ul class="vmenu"> 40 41<li><a href="#">1/12/2025</a></li> 42 <p>We published the <a href="https://academic.oup.com/bioinformatics/article/41/12/btaf641/8362222?login=false">TripLexicon</a>, our resource for RNA-DNA interactions. </p> 43 44 45 46<li><a href="#">1/10/2025</a></li> 47 <p>
47We welcome Christian as a new PhD student! </p> 48 49 <li><a href="#">1/06/2025</a></li> 50 <p>Congrats to Ranjan for his <a href="https://www.cell.com/trends/genetics/fulltext/S0168-9525(24)00317-2?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS0168952524003172%3Fshowall%3Dtrue">review</a> about methods for analysis of miRNA single cell data. </p> 51 52<li><a href="#">31/03/2025</a></li> 53 <p>We contributed to the <a href="https://journals.plos.org/ploscompbiol/article?id=10.1371/journal.pcbi.1012278">GeneCOCOA method</a> for prediction of gene function from co-expression data. </p> 54 55 56<li><a href="#">1/1/2025</a></li> 57 <p>We welcome Zlatka as a new PhD student! </p> 58 59<!--<li><a href="#">20/8/2024</a></li> 60 <p>New Phd and student assistant positions available. <a href="jobs.html"> Join us! </a></p> --> 61 62 <li><a href="#">1/7/2024</a></li> 63 <p>We welcome Seda as a new administrative assisstant! </p> 64 65 <li><a href="#">18/04/2024</a></li> 66 <p>Congrats to Nina for her <a href="https://www.cell.com/iscience/fulltext/S2589-0042(24)00987-8?_returnURL=https%3A%2F%2Flinkinghub.elsevier.com%2Fretrieve%2Fpii%2FS2589004224009878%3Fshowall%3Dtrue">paper</a> about the statistical method in <a href="https://github.com/SchulzLab/SNEEP">SNEEP</a>. </p> 67 68 <li><a href="#">1/3/2024</a></li> 69 <p>We celebrate the foundation of the Institute for Computational Genomic Medicine <a href="https://aktuelles.uni-frankfurt.de/forschung/genomforschung-mit-kuenstlicher-intelligenz-neue-professur-an-der-goethe-universitaet/">(info)</a>. </p> 70 71 72 <li><a href="#">20/11/2023</a></li> 73 <p>Computational analysis reveals novel regulators of Parkison's disease relevant neuronal cells <a href="https://www.embopress.org/doi/full/10.1038/s44319-023-00024-2">(paper)</a>. </p> 74 75 76 <li><a href="#">20/11/2023</a></li> 77 <p>Our review about multi-modal ML models is <a href="https://www.csbj.org/article/S2001-0370(23)00426-9/fulltext">published</a>. </p> 78 79 <li><a href="#">15/10/2023</a></li> 80 <p>
80We welcome Christina as a PhD student! </p> 81 82 <li><a href="#">14/9/2023</a></li> 83 <p>Our review about computational transcription factor models is <a href="https://analyticalsciencejournals.onlinelibrary.wiley.com/doi/10.1002/pmic.202200462">published</a>. </p> 84 85 <li><a href="#">25/07/2023</a></li> 86 <p>Our first <a href="https://github.com/SchulzLab/SNEEP">SNEEP</a> analysis for cardiovascular GWAS was <a href="https://humgenomics.biomedcentral.com/articles/10.1186/s40246-023-00513-4">published</a>. </p> 87 88 <li><a href="#">1/06/2023</a></li> 89 <p>Our fast approach for DNA bisulfite analysis is <a href="https://academic.oup.com/bioinformatics/article/39/6/btad386/7199582">published</a>. </p> 90<!-- 91 <li><a href="#">27/01/2023</a></li> 92 <p>Our new approach to link enhancers to genes is <a href="https://academic.oup.com/bioinformatics/advance-article/doi/10.1093/bioinformatics/btad062/7008325">published</a>. </p> 93 <li><a href="#">10/10/2022</a></li> 94 <p>We welcome Laura as a PhD student! </p> 95 96 <li><a href="#">13/10/2022</a></li> 97 <p>Our new optimization and prediction method for triplexes was <a href="https://academic.oup.com/bib/article/23/6/bbac445/6760135">published</a>. </p> 98 99 <li><a href="#">20/09/2021</a></li> 100 <p>Our ML paper linking epigenome and expression data for regulatory elements was <a href="https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gkab798/6368526">published</a>. </p> 101 <li><a href="#">15/09/2021</a></li> 102 <p>We welcome Shamim as new team member! </p> 103 104 <li><a href="#">1/07/2021</a></li> 105 <p>Our review about ML methods for disease prediction from genotype data <a href="https://www.degruyter.com/document/doi/10.1515/hsz-2021-0109/html">appeared</a>. </p> 106 <li><a href="#">27/11/2020</a></li> 107 <p>Our SCIDDO approach for diff segmentation analysis is <a href="https://doi.org/10.1093/bioinformatics/btaa960">out</a>. </p> 108 <li><a href="#">30/10/2020</a></li> 109 <p>Our paper about single cell TF analysis was <a href="https://academic.oup.com/gigascience/article/9/11/giaa113/5943496">published</a>. </p> 110 --> 111 <li><a href="#">18/8/2020</a></li> 112 <p>Congratulations to Florian Schmidt who won the <a href="https://gcb2020.de/Conference+Programme/Scientific+programme/_/Programm_GCB_2020_A4-web_09.10.pdf">FABI dissertation prize</a> 113 </p> 114 <!--<li><a href="#">1/8/2020</a></li> 115 <p>We welcome Florian Neukamm as a new member of the lab!</a> 116 </p> 117 118 <li><a href="#">24/07/2020</a></li> 119 <p>Florian Schmidt won the ISCB student software prize for the <a href="https://github.com/SchulzLab/TEPIC"> TEPIC software </a>. Congrats!</a> 120 </p> 121 <li><a href="#">27/05/2020</a></li> 122 <p>The paper about our Epiregio database was <a href="https://academic.oup.com/nar/article/48/W1/W193/5847772"> published</a>. 123 </p> 124 <li><a href="#">15/10/2019</a></li> 125 <p>We welcome Nikoletta Katsaouni as a new member of the lab!</a> 126 </p> 127 <li><a href="#">1/10/2019</a></li> 128 <p>We welcome Dennis Hecker and Ranjan Maji as new members of the lab! Great to have you here!</a> 129 </p> 130 <li><a href="#">16/4/2019</a></li> 131 <p>Two talks at ISMB in Basel this year! Come and see us, we have many <a href="https://schulzlab.github.io/jobs.html"> job openings.</a> 132 </p> 133 <li><a href="#">8/3/2019</a></li> 134 <p>Great week: our tool <a href="https://github.com/SchulzLab/RAPID">RAPID</a>, extensions to <a href="https://github.com/SchulzLab/ORNA">ORNA</a> and our SPONGE method were accepted. Congrats to everyone involved! More info soon! 135 </p> 136<!-- 137 <li><a href="#">1/2/2019</a></li> 138 <p>ATAC-seq bias correction and footprinting accepted in <a href="https://www.biorxiv.org/content/early/2018/07/17/362863"> Genome Biology</a>. Joint work with the <a href="http://costalab.org"> Costa Lab </a>. 139 </p> 140 <li><a href="#">14/12/2018</a></li> 141 <p>Our new ML approach for time-series epigenomic data integration was <a href="href=https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gky1240/5245443">published</a>. Work with the <a href="https://wwwen.uni.lu/research/fstc/life_sciences_research_unit/research_areas/systems_biology/epigenetics_team">Sinkkonen Lab</a></p> 142-->
142 143 144 145 146 </ul> 147 </div> 148 149 <div id="content"> 150 151 152 <div class="full"> 153 <!-- 154 <p><img src="img/front_new2.jpg" width="720" height="245" alt="sample content image"></p> --> 155<p> 156 <video src="img/SchulzLabIntro.mp4" width=720 height=520 controls poster="img/VideoTeaser.png"> 157Dies Video kann in Ihrem Browser nicht wiedergegeben werden.<br> 158Eine Download-Version steht unter <a href="URL">Link-Addresse</a> zum Abruf bereit. 159</video> 160</p> 161 162 163 164 165 <h2>About</h2> 166 <p> 167 The Institute for Computational Medicine works on computational approaches for the integrative analyses of large-scale datasets such as transcriptomics, epigenomics and proteomics. Our goal is to advance human medicine by designing computational methods to enable personalized medicine applications. These methods are being used in collaborative projects and in translational studies, such as the interpretation of noncoding disease mutations and patient-data based treatment decision making. Together with experimental groups we validate predictions that we make to advance biology and medicine. 168 <a href="projects.html">Projects</a> page for more info. </p> 169 170 171 <div class="left"> 172 <b>Contact:</b> 173 <br> 174 <br> 175 <b><FONT COLOR=#333333>Marcel H. Schulz </FONT></b><br> 176 Director <br> 177 Institute for Computational Genomic Medicine <br> 178 Theodor-Stern-Kai 7<br> 179 Haus 26, 4th floor, Room 409 <br> 180 Goethe University Frankfurt <br> 181 60590 Germany <br> 182 <img src="img/bildBrief2.gif" width="16" height="10" alt="sample content image" /> marcel.schulz|em.uni-frankfurt.de<br> 183 <img src="AltesFon.gif" width="20" height="15" alt="sample content image" /> +49 69 6301 86203 <br> 184 185</div> 186 <div id="footer"> 187 <p>Copyright © 2023 <a href="index.html">Marcel H. Schulz</a><br /> 188 Template design by <a href="http://andreasviklund.com/">Andreas Viklund</a></p> 189 190 </a> 191 192</div> 193</div> 194</body> 195</html>
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