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88 89 <div class="intro-text"> 90 <hr class="star-light"> 91 <span class="skills">Mathematical Biology - Epidemiology - Ecology</span> 92 </div> 93 </div> 94 </div> 95 </div> 96 </header> 97 98 <!-- Portfolio Grid Section --> 99 <section id="portfolio"> 100 <div class="container"> 101 <div class="row"> 102 <div class="col-lg-12 text-center"> 103 <h2>Research</h2> 104 <hr class="star-primary"> 105 </div> 106 </div> 107 <div class="row"> 108 <div class="col-sm-4 portfolio-item"> 109 <a href="#portfolioModal1" class="portfolio-link" data-toggle="modal"> 110 <div class="caption"> 111 <div class="caption-content"> 112 <h3>Statistical Methodologies<br></h3> 113 <i class="fa fa-search-plus fa-1x"></i> 114 </div> 115 </div> 116 <img src="img/portfolio/stats_scaled.png" class="img-responsive" alt=""> 117 </a> 118 </div> 119 <div class="col-sm-4 portfolio-item"> 120 <a href="#portfolioModal2" class="portfolio-link" data-toggle="modal"> 121 <div class="caption"> 122 <div class="caption-content"> 123 <h3>Lymphatic Filariasis<br> 124 Modelling<br></h3> 125 <i class="fa fa-search-plus fa-1x"></i> 126 </div> 127 </div> 128 <img src="img/portfolio/ntdlogo_scaled.png" class="img-responsive" alt=""> 129 </a> 130 </div> 131 <div class="col-sm-4 portfolio-item"> 132 <a href="#portfolioModal3" class="portfolio-link" data-toggle="modal"> 133 <div class="caption"> 134 <div class="caption-content"> 135 <h3>Simulation<br></h3> 136 <i class="fa fa-search-plus fa-1x"></i> 137 </div> 138 </div> 139 <img src="img/portfolio/host_diagram_scaled.png" class="img-responsive" alt=""> 140 </a> 141 </div> 142 <div class="col-sm-4 portfolio-item"> 143 <a href="#portfolioModal4" class="portfolio-link" data-toggle="modal"> 144 <div class="caption"> 145 <div class="caption-content"> 146 <h3>Modelling of Public Health 147 Interventions<br></h3> 148 <i class="fa fa-search-plus fa-1x"></i> 149 </div> 150 </div> 151 <img src="img/portfolio/intervention.jpg" class="img-responsive" alt=""> 152 </a> 153 </div> 154 <div class="col-sm-4 portfolio-item"> 155 <a href="#portfolioModal5" class="portfolio-link" data-toggle="modal"> 156 <div class="caption"> 157 <div class="caption-content"> 158 <h3>Online Modelling<br> 159 Tools<br></h3> 160 <i class="fa fa-search-plus fa-1x"></i> 161 </div> 162 </div> 163 <img src="img/portfolio/GUI_scaled.png" class="img-responsive" alt=""> 164 </a> 165 </div> 166 <div class="col-sm-4 portfolio-item"> 167 <a href="#portfolioModal6" class="portfolio-link" data-toggle="modal"> 168 <div class="caption"> 169 <div class="caption-content"> 170 <h3>Pattern Formation<br></h3> 171 <i class="fa fa-search-plus fa-1x"></i> 172 </div> 173 </div> 174 <img src="img/portfolio/seagrass1_scaled.jpg" class="img-responsive" alt=""> 175 </a> 176 </div> 177 </div> 178 </div> 179 </section> 180 181 <!-- About Section --> 182 <section id="about"> 183 <div class="container"> 184 <div class="row"> 185 <div class="col-lg-12 text-center"> 186 <h2>About</h2> 187 <hr class="star-primary"> 188 </div> 189 </div> 190 <div class="row"> 191 <div class="col-lg-4 col-lg-offset-2"> 192 <p> 193 I am currently a senior scientist at the 194 <a href="http://www.bccdc.ca/our-research/people/mike-irvine">British Columbia Centre for Disease Control</a> and 195 an <a href="https://www.sfu.ca/fhs/about/people/profiles/michael-irvine.html">adjunct professor at Simon Fraser University in the Faculty of Health Sciences</a>. 196 Previously, I was a postdoctoral research fellow at the 197 <a href="https://www.math.ubc.ca/Research/MathBio/index.php"> 198 University of British Columbia</a>, the 199 <a href="http://www.bccdc.ca/our-research">British 200 Columbia Centre for Disease Control</a> and the 201 <a href="https://www2.gov.bc.ca/gov/content/governments/organizational-structure/ministries-organizations/ministries/mental-health-addictions"> 202 BC Ministry of Mental Health and Addictions</a>. 203 I use an array of approaches from Bayesian 204 statistics and mathematical modelling. 205 </p> 206 207 </div> 208 <div class="col-lg-4"> 209 <p> 210 I also completed a postdoctoral fellowship at the 211 <a href="http://www2.warwick.ac.uk/fac/cross_fac/wider/"> 212 University of Warwick</a> 213 modelling the elimination of lympahtic filariasis 214 as part of the neglected tropical disease modelling 215 consortium. 216 </p> 217 <p> 218 I completed a PhD in the modelling of pattern 219 formation in ecology as part of the University of Warwick
220 Centre for Complexity Science. 221 </p> 222 <p> 223 I am passionate about using a wide-variety of analytic and 224 statistical tools to get the most insight from data 225 available; from data-mining to inference and model-based 226 prediction. 227 </p> 228 <p> 229 I am always interested in new opportunities for 230 collaboration. My contact details are below. 231 </p> 232 </div> 233 <!-- 234 <div class="col-lg-8 col-lg-offset-2 text-center"> 235 <a href="#" class="btn btn-lg btn-outline"> 236 <i class="fa fa-download"></i> Download Theme 237 </a> 238 </div> 239 --> 240 </div> 241 </div> 242 </section> 243 244 <!-- Publications Section --> 245 <section id="publications"> 246 <div class="container"> 247 <div class="row"> 248 <div class="col-lg-12 text-center"> 249 <h2>Selected publications</h2> 250 <hr class="star-primary"> 251 </div> 252 </div> 253 <div class="row"> 254 <div class="col-lg-12 text-center"> 255 <ul class="list-group"> 256 257 <li class="list-group-item"> 258 <a href="https://doi.org/10.1016/S2468-2667(21)00304-2">Estimating naloxone need in the USA across fentanyl, heroin, and prescription opioid epidemics: a modelling study</a>.<br> 259 <b>Irvine MA</b>, Oller D, Boggis J, Bishop B, Coombs D, Wheeler E, Doe-Simkins M, Walley AY, Marshall BD, Bratberg J, Green TC<br> 260 <i>The Lancet Public Health</i> (2022)<br> 261 Website: <a href="http://naloxoneneededtosave.org">How much naloxone is needed to save?</a> 262 </li> 263 <li class="list-group-item"> 264 <a href="https://doi.org/10.1098/rsos.211710">Quantifying transmissibility of SARS-CoV-2 and impact of intervention within long-term healthcare facilities</a>.<br> 265 Stockdale JE, Anderson SC, Edwards AM, Iyaniwura SA, Mulberry N, Otterstatter MC, Janjua NZ, Coombs D, Colijn C, <b>Irvine MA</b><br> 266 <i>Royal Society Open Science</i> (2022)<br> 267 Software: <a href="https://sempwn.github.io/cr0eso/">Cr0eso R package</a>. 268 </li> 269 <li class="list-group-item"> 270 <a href="https://doi.org/10.1371/journal.pcbi.1008274">An Interrupted Time-Series Analysis of Pediatric Emergency Department Visits During the Coronavirus Disease 2019 Pandemic</a>.<br> 271 <b>Irvine MA</b>, Portales-Casamar E, Goldman RD<br> 272 <i>Pediatric emergency care</i> (2021)<br> 273 </li> 274 <li class="list-group-item"> 275 <a href="https://doi.org/10.1016/j.ijid.2020.11.163">Severe COVID-19 infection and pediatric comorbidities: a systematic review and meta-analysis</a>.<br> 276 Tsankov BK, Allaire JM, <b>Irvine MA</b>, Lopez AA, Sauvé LJ, Vallance BA, Jacobson K<br> 277 <i>International Journal of Infectious Diseases.</i> (2021)<br> 278 </li> 279 <li class="list-group-item"> 280 <a href="https://doi.org/10.1016/j.drugpo.2020.102726">How simulation modeling can support the public health response to the opioid crisis in North America: setting priorities and assessing value</a>.<br> 281 Bansback NJ, Barbosa C, Barocas J, Bayoumi AM, Behrends C, Chhatwal J, Cipriano LE, Coffin P, Goldhaber-Fiebert J, Hoch JS, <b>Irvine MA</b><br> 282 <i>The International journal of drug policy</i> (2021)<br> 283 </li> 284 <li class="list-group-item"> 285 <a href="https://doi.org/10.1371/journal.pcbi.1008274">Quantifying the impact of COVID-19 control measures using a Bayesian model of physical distancing</a>.<br>
286 Anderson SC, Edwards AM, Yerlanov M, Mulberry N, Stockdale JE, Iyaniwura SA, Falcao RC, Otterstatter MC, <b>Irvine MA</b>, Janjua NZ, Coombs D, Colijn C<br> 287 <i>PLoS Computational Biology</i> (2020)<br> 288 Software: <a href="https://github.com/seananderson/covidseir">Github repository</a>. 289 </li> 290 <li class="list-group-item"> 291 <a href="http://dx.doi.org/10.1136/emermed-2020-210273">Paediatric patients seen in 18 emergency departments during the COVID-19 pandemic</a>.<br> 292 Goldman RD, Grafstein E, Barclay N, <b>Irvine MA</b>, Portales-Casamar E<br> 293 <i>Emergency Medicine Journal</i> (2020)<br> 294 </li> 295 <li class="list-group-item"> 296 <a href="https://doi.org/10.1016/j.drugalcdep.2020.108337">Estimates of opioid use disorder prevalence from a regression-based multi-sample stratified capture-recapture analysis</a>.<br> 297 Min JE, Pearce LA, Homayra F, Dale LM, Barocas JA, <b>Irvine MA</b>, Slaunwhite AK, McGowan G, Torban M, Nosyk B<br> 298 <i>Drug and Alcohol Dependence</i> (2020)<br> 299 </li> 300 <li class="list-group-item"> 301 <a href="https://doi.org/10.1016/j.ijid.2020.11.163">Severe COVID-19 infection and pediatric comorbidities: a systematic review and meta-analysis</a>.<br> 302 Tsankov BK, Allaire JM, <b>Irvine MA</b>, Lopez AA, Sauve LJ, Vallance BA, Jacobson K<br> 303 <i>International Journal of Infectious Diseases</i> (2020)<br> 304 </li> 305 <li class="list-group-item"> 306 <a href="https://doi.org/10.1371/journal.pntd.0008644">Defining a prevalence level to describe the elimination of Lymphatic Filariasis (LF) transmission and designing monitoring & evaluating (M&E) programmes post the cessation of mass drug administration (MDA)</a>.<br> 307 Collyer BS, <b>Irvine MA</b>, Hollingsworth TD, Bradley M, Anderson RM<br> 308 <i>PLoS Neglected Tropical Diseases</i> (2020)<br> 309 </li> 310 <li class="list-group-item"> 311 <a href="https://dx.doi.org/10.1007%2Fs11524-020-00441-x">Modeling COVID-19 and Its Impacts on US Immigration and Customs Enforcement (ICE) Detention Facilities, 2020</a>.<br> 312 <b>Irvine MA</b>, Coombs D, Skarha J, del Pozo B, Rich J, Taxman F, Green TC<br> 313 <i>Journal of Urban Health: Bulletin of the New York Academy of Medicine</i> (2020)<br> 314 </li> 315 <li class="list-group-item"> 316 <a href="https://doi.org/10.1136/bmj.m772">Opioid agonist treatment and risk of mortality during opioid overdose public health emergency: population based retrospective cohort study</a>.<br> 317 Pearce LA, Min JE, Piske M, Zhou H, Homayra F, Slaunwhite A, <b>Irvine MA</b>, McGowan G, Nosyk B<br> 318 <i>BMJ</i> (2020)<br> 319 </li> 320 <li class="list-group-item"> 321 <a href="https://doi.org/10.1371/journal.pcbi.1006869">The use of mixture density networks in the emulation of complex epidemiological individual-based models</a>.<br> 322 Davis CN, Hollingsworth TD, Caudron Q, <b>Irvine MA</b><br> 323 <i>PLoS computational biology</i> (2020)<br> 324 Software: <a href="https://github.com/QCaudron/pydra">Github repository</a>. 325 </li> 326 <li class="list-group-item"> 327 <a href="https://doi.org/10.1016/j.drugpo.2019.11.011">The role of mathematical modelling in aiding public health policy decision-making: A case study of the BC opioid overdose emergency</a>.<br> 328 <b>Irvine MA</b>, McGowan R, Hammond K, Davison C, Coombs D, Gilbert M<br> 329 <i>International Journal of Drug Policy</i> (2019)<br> 330 </li> 331 <li class="list-group-item"> 332 <a href="https://doi.org/10.1016/j.epidem.2019.100360">Predicting the impact of clustered risk and testing behaviour patterns on the population-level effectiveness of pre-exposure prophylaxis against HIV among gay, bisexual and other men who have sex with men in Greater Vancouver, Canada</a>.<br> 333 <b>Irvine MA</b>, Salway T, Grennan T, Wong J, Gilbert M, Coombs D<br> 334 <i>Epidemics</i> (2019)<br> 335 </li> 336 <li class="list-group-item"> 337 <a href="https://doi.org/10.1016/S2468-2667(18)30044-6">Modelling the combined impact of interventions in averting deaths during a syntheticâopioid overdose epidemic</a>.<br> 338 <b>Irvine MA</b>, Buxton JA, Otterstatter M, Balshaw R, Gustafson R, Tyndall M, Kendall P, Kerr Thomas, Gilbert M, and Coombs D<br> 339 <i>Addiction</i> (2019)<br> 340 News coverage: <a href="https://www.cbc.ca/news/canada/british-columbia/bc-od-crisis-lives-saved-1.5163581">CBC news</a>, 341 <a href="https://www.theglobeandmail.com/canada/british-columbia/article-unsanctioned-overdose-prevention-site-opens-in-maple-ridge-renewing/">Globe and Mail</a>, 342 <a href="https://nationalpost.com/pmn/news-pmn/canada-news-pmn/rapid-response-to-b-c-s-overdose-crisis-saved-thousands-report-finds">National Post</a>, 343 <a href="https://www.straight.com/news/1252756/without-harm-reduction-overdoses-would-have-killed-thousands-more-bc-analysis-finds">Georgia Straight</a> 344 </li> 345 <li class="list-group-item"> 346 <a href="https://doi.org/10.1093/cid/ciy003">Are Alternative Strategies Required to Accelerate the Global Elimination of Lymphatic Filariasis? Insights From Mathematical Models</a>.<br> 347 Stolk WA, Prada JM, Smith ME, Kontoroupis P, de Vos AS, 348 Touloupou P, <b>Irvine MA</b>, Brown P, Subramanian S, Kloek M, 349 Michael E, Hollingsworth TD, and de Vlas SJ<br> 350 <i>Clinical Infectious Diseases</i> (2018)<br> 351 </li> 352 <li class="list-group-item"> 353 <a href="https://doi.org/10.1016/j.epidem.2018.05.009">Kernel-density estimation and approximate Bayesian computation for flexible epidemiological model fitting in Python</a>.<br> 354 <b>Irvine MA</b>, and Hollingsworth TD<br> 355 <i>Epidemics</i> (2018)<br>
356 Software: <a href="https://github.com/sempwn/ABCPRC">Github repository</a> 357 </li> 358 <li class="list-group-item"> 359 <a href="https://doi.org/10.1016/S2468-2667(18)30044-6">Distribution of take-home opioid antagonist kits during a synthetic opioid epidemic in British Columbia, Canada: a modelling study</a>.<br> 360 <b>Irvine MA</b>, Buxton JA, Otterstatter M, Balshaw R, Gustafson R, Tyndall M, Kendall P, Kerr Thomas, Gilbert M, and Coombs D<br> 361 <i>The Lancet Public Health</i> (2018)<br> 362 News coverage: <a href="https://bc.ctvnews.ca/video?clipId=1373929">CTV news</a>, 363 <a href="http://www.cbc.ca/news/canada/british-columbia/take-home-naloxone-program-bc-1.4625201?cmp=rss">CBC news</a>, 364 <a href="http://vancouversun.com/health/local-health/making-naloxone-freely-available-reduced-fentanyl-overdose-deaths-in-b-c-study">Vancouver Sun</a>, 365 <a href="http://www.radionl.com/2018/04/18/6754/">Radio NL</a>, 366 <a href="http://www.theprovince.com/health/local-health/making+naloxone+freely+available+reduced+fentanyl/17305501/story.html">The Province</a>, and 367 <a href="https://www.reuters.com/article/us-health-overdose/take-home-narcan-kits-lifesaving-in-opioid-overdoses-idUSKBN1I2416">Reuters</a>. 368 </li> 369 <li class="list-group-item"> 370 <a href="https://doi.org/10.1098/rsif.2017.0849">A novel Bayesian approach to predicting reductions in HIV incidence following increased testing interventions among gay, bisexual and other men who have sex with men in Vancouver, Canada</a>.<br> 371 <b>Irvine MA</b>, Konrad BP, Balshaw R, Gilbert M, and Coombs D<br> 372 <i>Roy. Soc. Interface</i> (2018)<br> 373 Blog post: <a href="https://medium.com/ubcscience/bayesian-analysis-sciences-best-attempt-at-fortune-telling-c862bdd290eb">Medium</a>. 374 </li> 375 <li class="list-group-item"> 376 <a href="http://dx.doi.org/10.1098/rspb.2017.2253">Understanding heterogeneities in mosquito-bite exposure and infection distributions for the elimination of lymphatic filariasis</a>.<br> 377 <b>Irvine MA</b>, Kazura JW, Hollingsworth TD, and Reimer LJ<br> 378 <i>Proc. Roy. Soc. B.</i> (2018)<br> 379 News coverage: <a href="http://www.lstmed.ac.uk/news-events/news/the-importance-of-heterogeneity-on-the-management-of-vector-borne-diseases">LSTM news</a>. 380 </li> 381 <li class="list-group-item"> 382 <a href="http://dx.doi.org/10.1038/s41598-017-17346-6">Conservation of pattern as a tool for inference on spatial snapshots in ecological data</a>.<br> 383 <b>Irvine MA</b>, Bull JC, and Keeling MJ<br> 384 <i>Scientific Reports.</i> (2018) 385 </li> 386 <li class="list-group-item"> 387 <a href="http://dx.doi.org/10.1016/S2352-3018(17)30123-6">Cost-effectiveness of screening for HIV in primary care: a health economics modelling analysis</a>.<br> 388 Baggaley RF, <b>Irvine MA</b>, Leber W, Cambiano V, Figueroa J, McMullen H, Anderson J, Santos AC , Terris-Prestholt F, Miners A, Hollingsworth TD, and Griffiths CJ<br> 389 <i>The Lancet HIV.</i> (2017)<br> 390 News coverage: <a href="http://www.bbc.com/news/health-40756196">BBC news</a>, <a href="http://www.telegraph.co.uk/science/2017/07/30/hiv-tests-should-offered-everyone-high-risk-areas-enroll-new/">The Telegraph</a>, 391 <a href="https://www.theguardian.com/society/2017/jul/30/hiv-tests-for-gps-new-patients-could-save-lives-and-money-says-study">The Guardian</a>, 392 <a href="https://www.newscientist.com/article/2142100/">New Scientist</a>, and 393 <a href="https://www.thetimes.co.uk/article/call-to-make-family-doctors-test-all-patients-for-hiv-p5qq50qzq">The Times</a>. 394 <br> 395 Outcomes: <a href="https://ecdc.europa.eu/sites/portal/files/documents/HIV-hepatitis-B-and-C-testing-public-health-guidance.pdf">Public health guidance on HIV, hepatitis B and C testing in the EU/EEA</a>. 396 </li> 397 <li class="list-group-item"> 398 <a href="http://dx.doi.org/10.1016/j.epidem.2017.02.006">Predicting lymphatic filariasis transmission and elimination dynamics using a multi-model ensemble framework</a>.<br> 399 Smith ME, Singh BK, <b>Irvine MA</b>, Stolk WA, Subramanian S, Hollingsworth TD, and Michael E<br> 400 <i>Epidemics.</i> (2017) 401 </li> 402 <li class="list-group-item"> 403 <a href="http://dx.doi.org/10.1371/journal.pntd.0005206"> Making transmission models accessible to end-users: the example of TRANSFIL</a>.<br> 404 <b>Irvine MA</b>, and Hollingsworth TD<br> 405 <i>PLoS Neglected Tropical Diseases</i>. (2017)<br> 406 Outcomes: <a href="https://sempwn.github.io/TRANSFIL2/">Online interactive dashboard</a>. 407 </li> 408 <li class="list-group-item"> 409 <a href="http://dx.doi.org/10.1016/S1473-3099(16)30467-4">Effectiveness of a triple-drug regimen for global elimination of lymphatic filariasis: a modelling study</a>.<br> 410 <b>Irvine MA</b>, Stolk WA, Smith ME, Subramanian S, Singh BK, Weil GJ, Michael E, and Hollingsworth TD <br> 411 <i>The Lancet Infectious Diseases</i>. (2016)<br> 412 Outcomes: 413 <a href="http://www.who.int/lymphatic_filariasis/resources/9789241550161/en/"> 414 World Health Organisation guidelines on 415 alternative mass drug administration 416 regimens to eliminate lymphatic filariasis 417 </a>. 418 </li> 419 <li class="list-group-item"> 420 <a href="http://dx.doi.org/10.1098/rsif.2016.0463">Disease transmission promotes evolution of host spatial patterns</a>.<br> 421 <b>Irvine MA</b>, Bull JC, and Keeling MJ <br> 422 <i>Journal of the Royal Society Interface</i>. (2016)<br> 423 </li> 424 <li class="list-group-item"> 425 <a href="http://dx.doi.org/10.1016/j.tpb.2015.12.001">Aggregation dynamics explain vegetation patch-size distributions</a>.<br> 426 <b>Irvine MA</b>, Bull JC, and Keeling MJ<br> 427 <i>Theoretical population biology</i>. (2016) <br> 428 </li> 429 <li class="list-group-item"> 430 <a href="http://dx.doi.org/10.1098/rsos.150519">Fractal measures of spatial pattern as a heuristic for return rate in vegetative systems</a>.<br> 431 <b>Irvine MA</b>, Jackson EL, Kenyon EJ, Cook KJ, Keeling MJ, and Bull JC<br> 432 <i>Royal Society open science</i>. (2016) <br> 433 </li> 434 435 <li class="list-group-item"> 436 <a href="http://dx.doi.org/10.1093/trstmh/trw024">Understanding the relationship between prevalence of microfilariae and antigenaemia using a model of lymphatic filariasis infection</a>.<br> 437<b>Irvine MA</b>, Njenga SM, Gunawardena S, Wamae CN, Cano J, Brooker SJ, and Hollingsworth TD <br> 438<i>Transactions of The Royal Society of Tropical Medicine and Hygiene.</i> (2016) <br> 439 </li> 440 441 <li class="list-group-item"> 442 <a href="http://dx.doi.org/10.1186/s13071-015-1152-3">Modelling strategies to break transmission of lymphatic filariasis-aggregation, adherence and vector competence greatly alter elimination</a>.<br> 443<b>Irvine MA</b>, Reimer LJ, Njenga SM, Gunawardena S, Kelly-Hope L, Bockarie M, and Hollingsworth TD<br> 444<i>Parasites & vectors</i>. (2015) <br> 445 </li> 446 447 <li class="list-group-item"> 448 <a href="http://dx.doi.org/10.1186/s13071-015-1235-1">
448Quantitative analyses and modelling to support achievement of the 2020 goals for nine neglected tropical diseases</a>.<br> 449Hollingsworth TD, Adams ER, Anderson RM, Atkins K, Bartsch S, Basáñez MG, Behrend M, Blok DJ, Chapman LA, Coffeng L, Courtenay O,…, <b>Irvine MA</b>, …, and NTD Modelling Consortium <br> 450<i>Parasites & vectors</i>. (2015) <br> 451 </li> 452 453 454 </ul> 455 </div> 456 </div> 457 </div> 458 </section> 459 460 461 <!-- Contact Section --> 462 <section id="contact"> 463 <div class="container"> 464 <div class="row"> 465 <div class="col-lg-12 text-center"> 466 <h2>Contact Me</h2> 467 <hr class="star-primary"> 468 </div> 469 </div> 470 <div class="row"> 471 <div class="col-lg-8 col-lg-offset-2"> 472 <!-- To configure the contact form email address, go to mail/contact_me.php and update the email address in the PHP file on line 19. --> 473 <!-- The form should work on most web servers, but if the form is not working you may need to configure your web server differently. --> 474 <form name="sentMessage" id="contactForm" novalidate> 475 <div class="row control-group"> 476 <div class="form-group col-xs-12 floating-label-form-group controls"> 477 <label>Name</label> 478 <input type="text" class="form-control" placeholder="Name" id="name" required data-validation-required-message="Please enter your name."> 479 <p class="help-block text-danger"></p> 480 </div> 481 </div> 482 <div class="row control-group"> 483 <div class="form-group col-xs-12 floating-label-form-group controls"> 484 <label>Message</label> 485 <textarea rows="5" class="form-control" placeholder="Message" id="message" required data-validation-required-message="Please enter a message."></textarea> 486 <p class="help-block text-danger"></p> 487 </div> 488 </div> 489 <br> 490 <div id="success"></div> 491 <div class="row"> 492 <div class="form-group col-xs-12"> 493 <button type="submit" class="btn btn-success btn-lg">Send</button> 494 </div> 495 </div> 496 </form> 497 </div> 498 </div> 499 </div> 500 </section> 501 502 <!-- Footer --> 503 <footer class="text-center"> 504 <div class="footer-above"> 505 <div class="container"> 506 <div class="row"> 507 <div class="footer-col col-md-4"> 508 <h3>Location</h3> 509 <p>Vancouver, CA</p> 510 </div> 511 <div class="footer-col col-md-4"> 512 <h3>Around the Web</h3> 513 <ul class="list-inline"> 514 <li> 515 <a href="https://www.researchgate.net/profile/Michael_Irvine5" class="btn-social btn-outline"><i class="ai ai-fw ai-researchgate"></i></a> 516 </li> 517 <li> 518 <a href="https://github.com/sempwn" class="btn-social btn-outline"><i class="fa fa-fw fa-github"></i></a> 519 </li> 520 <li> 521 <a href="https://twitter.com/MikeAIrvine" class="btn-social btn-outline"><i class="fa fa-fw fa-twitter"></i></a> 522 </li> 523 <li> 524 <a href="https://www.linkedin.com/in/mikeairvine" class="btn-social btn-outline"><i class="fa fa-fw fa-linkedin"></i></a> 525 </li> 526 527 <li> 528 <a href="https://scholar.google.ca/citations?user=k0Z-4Z8AAAAJ&hl=en" class="btn-social btn-outline"><i class="ai ai-fw ai-google-scholar"></i></a> 529 </li> 530 </ul> 531 </div> 532 <div class="footer-col col-md-4"> 533 <h3>Contact</h3> 534 <p><a href="mailto:[email protected]">[email protected]</a></p> 535 </div> 536 </div> 537 </div> 538 </div> 539 <div class="footer-below"> 540 <div class="container"> 541 <div class="row"> 542 <div class="col-lg-6">
543 Copyright © Mike Irvine 2017 544 </div> 545 <div class="col-lg-6"> 546 Template by <a href="https://startbootstrap.com">Start Bootstrap</a> 547 </div> 548 </div> 549 </div> 550 </div> 551 </footer> 552 553 <!-- Scroll to Top Button (Only visible on small and extra-small screen sizes) --> 554 <div class="scroll-top page-scroll hidden-sm hidden-xs hidden-lg hidden-md"> 555 <a class="btn btn-primary" href="#page-top"> 556 <i class="fa fa-chevron-up"></i> 557 </a> 558 </div> 559 560 <!-- Portfolio Modals --> 561 <div class="portfolio-modal modal fade" id="portfolioModal1" tabindex="-1" role="dialog" aria-hidden="true"> 562 <div class="modal-content"> 563 <div class="close-modal" data-dismiss="modal"> 564 <div class="lr"> 565 <div class="rl"> 566 </div> 567 </div> 568 </div> 569 <div class="container"> 570 <div class="row"> 571 <div class="col-lg-8 col-lg-offset-2"> 572 <div class="modal-body"> 573 <h2>Statistical Methodologies</h2> 574 <hr class="star-primary"> 575 <img src="img/portfolio/stats_scaled.png" class="img-responsive img-centered" alt=""> 576 <p> 577 Data in ecology and epidemiology is often sparse and noisy. 578 The goal is to be able to perform model fitting based on these data combined with expert knowledge. 579 Using Bayesian methodologies allows unknowns to be taken into account and to avoid over-fitting. 580 My research goals are to leverage the full information from data in order to better inform modelling work. 581 </p> 582 <h3> Publications </h3> 583 <ul class="list-group"> 584 <li class="list-group-item"> 585 <a href="https://doi.org/10.1016/j.epidem.2018.05.009">Kernel-density estimation and approximate Bayesian computation for flexible epidemiological model fitting in Python</a>.<br> 586 <b>Irvine MA</b>, and Hollingsworth TD 587 <i>Epidemics</i> (2018)<br> 588 Software: <a href="https://github.com/sempwn/ABCPRC">Github repository</a> 589 </li> 590 <li class="list-group-item"> 591 <a href="https://doi.org/10.1016/S2468-2667(18)30044-6">Distribution of take-home opioid antagonist kits during a synthetic opioid epidemic in British Columbia, Canada: a modelling study</a>.<br> 592 <b>Irvine MA</b>, Buxton JA, Otterstatter M, Balshaw R, Gustafson R, Tyndall M, Kendall P, Kerr Thomas, Gilbert M, and Coombs D 593 <i>The Lancet Public Health</i> (2018)<br> 594 News coverage: <a href="https://bc.ctvnews.ca/video?clipId=1373929">CTV news</a>, 595 <a href="http://www.cbc.ca/news/canada/british-columbia/take-home-naloxone-program-bc-1.4625201?cmp=rss">CBC news</a>, 596 <a href="http://vancouversun.com/health/local-health/making-naloxone-freely-available-reduced-fentanyl-overdose-deaths-in-b-c-study">Vancouver Sun</a>, 597 <a href="http://www.radionl.com/2018/04/18/6754/">Radio NL</a>, 598 <a href="http://www.theprovince.com/health/local-health/making+naloxone+freely+available+reduced+fentanyl/17305501/story.html">The Province</a>, 599 <a href="https://bc.ctvnews.ca/video?binId=1.1184759">CTV News</a> 600 </li> 601 <li class="list-group-item"> 602 <a href="https://doi.org/10.1098/rsif.2017.0849">A novel Bayesian approach to predicting reductions in HIV incidence following increased testing interventions among gay, bisexual and other men who have sex with men in Vancouver, Canada</a>.<br> 603 <b>Irvine MA</b>, Konrad BP, Balshaw R, Gilbert M, and Coombs D 604 <i>Roy. Soc. Interface</i> (2018)<br> 605 Blog post: <a href="https://medium.com/ubcscience/bayesian-analysis-sciences-best-attempt-at-fortune-telling-c862bdd290eb">Medium</a>. 606 </li> 607 <li class="list-group-item"> 608 <a href="http://dx.doi.org/10.1098/rspb.2017.2253">Understanding heterogeneities in mosquito-bite exposure and infection distributions for the elimination of lymphatic filariasis</a>.<br> 609 <b>Irvine MA</b>, Kazura JW, Hollingsworth TD, and Reimer LJ 610 <i>Proc. Roy. Soc. B.</i> (2018)<br> 611 News coverage: <a href="http://www.lstmed.ac.uk/news-events/news/the-importance-of-heterogeneity-on-the-management-of-vector-borne-diseases">LSTM news</a>. 612 </li> 613 <li class="list-group-item"> 614 <a href="http://dx.doi.org/10.1038/s41598-017-17346-6">Conservation of pattern as a tool for inference on spatial snapshots in ecological data</a>.<br> 615 <b>Irvine MA</b>, Bull JC, Keeling MJ. 616 <i>Scientific Reports.</i> (2018) 617 </li> 618 <li class="list-group-item"> 619 <a href="http://dx.doi.org/10.1016/j.epidem.2017.02.006">Predicting lymphatic filariasis transmission and elimination dynamics using a multi-model ensemble framework</a>.<br> 620 Smith ME, Singh BK, <b>Irvine MA</b>, Wilma A. Stolk, Subramanian S, Hollingsworth TD, Michael E. 621 <i>Epidemics.</i> (2017) 622 </li> 623 <li class="list-group-item"> 624 <a href="http://dx.doi.org/10.1093/trstmh/trw024">Understanding the relationship between prevalence of microfilariae and antigenaemia using a model of lymphatic filariasis infection</a>.<br> 625 Irvine MA, Njenga SM, Gunawardena S, Wamae CN, Cano J, Brooker SJ, Hollingsworth TD. 626 <i>Transactions of The Royal Society of Tropical Medicine and Hygiene.</i> 627 <b>110</b>(2) pp. 118-24 (2016) 628 </li> 629 </ul> 630 <button type="button" class="btn btn-default" data-dismiss="modal"><i class="fa fa-times"></i> Close</button> 631 </div> 632 </div> 633 </div> 634 </div> 635 </div> 636 </div> 637 <div class="portfolio-modal modal fade" id="portfolioModal2" tabindex="-1" role="dialog" aria-hidden="true"> 638 <div class="modal-content"> 639 <div class="close-modal" data-dismiss="modal"> 640 <div class="lr"> 641 <div class="rl"> 642 </div> 643 </div> 644 </div> 645 <div class="container"> 646 <div class="row"> 647 <div class="col-lg-8 col-lg-offset-2"> 648 <div class="modal-body"> 649 <h2>Lymphatic Filariasis</h2> 650 <hr class="star-primary"> 651 <img src="img/portfolio/ntdlogo_scaled.png" class="img-responsive img-centered" alt=""> 652 <p> 653 As part of the Neglected Tropical Diseases modelling consortium, I investigated the elimination of lymphatic filariasis as a global public health problem. 654 Lymphatic filariasis or elephantiasis is a mosquito-borne parasitic infection that can cause swelling of the limbs and testes. 655 Currently 790 million people are at risk of the disease and 68 million are currently infected with a further 20 million suffering from chronic morbidity. 656 657 </p> 658 <h3> Publications </h3> 659 <ul class="list-group"> 660 <li class="list-group-item"> 661 <a href="https://doi.org/10.1093/cid/ciy003">Are Alternative Strategies Required to Accelerate the Global Elimination of Lymphatic Filariasis? Insights From Mathematical Models</a>.<br> 662 Stolk WA, Prada JM, Smith ME, Kontoroupis P, de Vos AS, 663 Touloupou P, <b>Irvine MA</b>, Brown P, Subramanian S, Kloek M, 664 Michael E, Hollingsworth TD, and de Vlas SJ 665 <i>Clinical Infectious Diseases</i> (2018)<br> 666 </li> 667 <li class="list-group-item"> 668 <a href="https://doi.org/10.1016/j.epidem.2018.05.009">Kernel-density estimation and approximate Bayesian computation for flexible epidemiological model fitting in Python</a>.<br> 669 <b>Irvine MA</b>, and Hollingsworth TD 670 <i>Epidemics</i> (2018)<br>
671 Software: <a href="https://github.com/sempwn/ABCPRC">Github repository</a> 672 </li> 673 <li class="list-group-item"> 674 <a href="http://dx.doi.org/10.1098/rspb.2017.2253">Understanding heterogeneities in mosquito-bite exposure and infection distributions for the elimination of lymphatic filariasis</a>.<br> 675 <b>Irvine MA</b>, Kazura JW, Hollingsworth TD, and Reimer LJ 676 <i>Proc. Roy. Soc. B.</i> (2018)<br> 677 News coverage: <a href="http://www.lstmed.ac.uk/news-events/news/the-importance-of-heterogeneity-on-the-management-of-vector-borne-diseases">LSTM news</a>. 678 </li> 679 <li class="list-group-item"> 680 <a href="http://dx.doi.org/10.1016/j.epidem.2017.02.006">Predicting lymphatic filariasis transmission and elimination dynamics using a multi-model ensemble framework</a>.<br> 681 Smith ME, Singh BK, <b>Irvine MA</b>, Wilma A. Stolk, Subramanian S, Hollingsworth TD, Michael E. 682 <i>Epidemics</i>. (2017) 683 </li> 684 <li class="list-group-item"> 685 <a href="http://dx.doi.org/10.1016/S1473-3099(16)30467-4">Effectiveness of a triple-drug regimen for global elimination of lymphatic filariasis: a modelling study</a>.<br> 686 <b>Irvine MA</b>, Stolk WA, Smith ME, Subramanian S, Singh BK, Weil GJ, Michael E, Hollingsworth TD. <i>The Lancet Infectious Diseases</i>. (2016) 687 <br> Outcomes: 688 <a href="http://www.who.int/lymphatic_filariasis/resources/9789241550161/en/"> 689 World Health Organisation guidelines on 690 alternative mass drug administration 691 regimens to eliminate lymphatic filariasis. 692 </a> 693 </li> 694 <li class="list-group-item"> 695 <a href="http://dx.doi.org/10.1093/trstmh/trw024">Understanding the relationship between prevalence of microfilariae and antigenaemia using a model of lymphatic filariasis infection</a>.<br> 696 <b>Irvine MA</b>, Njenga SM, Gunawardena S, Wamae CN, Cano J, Brooker SJ, Hollingsworth TD. 697 <i>Transactions of The Royal Society of Tropical Medicine and Hygiene.</i> 698 <b>110</b>(2) pp. 118-24 (2016) 699 </li> 700 701 <li class="list-group-item"> 702 <a href="http://dx.doi.org/10.1186/s13071-015-1152-3">Modelling strategies to break transmission of lymphatic filariasis-aggregation, adherence and vector competence greatly alter elimination</a>.<br> 703 <b>Irvine MA</b>, Reimer LJ, Njenga SM, Gunawardena S, Kelly-Hope L, Bockarie M, Hollingsworth TD. 704 <i>Parasites & vectors.</i> 705 <b>8</b>(1) pp. 1 (2015) 706 </li> 707 708 <li class="list-group-item"> 709 <a href="http://dx.doi.org/10.1186/s13071-015-1235-1">Quantitative analyses and modelling to support achievement of the 2020 goals for nine neglected tropical diseases</a>.<br> 710 Hollingsworth TD, Adams ER, Anderson RM, Atkins K, Bartsch S, Basáñez MG, Behrend M, Blok DJ, Chapman LA, Coffeng L, Courtenay O, <b>Irvine MA</b>,…, NTD Modelling Consortium. 711 <i>Parasites & vectors.</i> 712 <b>8</b>(1) pp. 1 (2015) 713 </li> 714 </ul> 715 <button type="button" class="btn btn-default" data-dismiss="modal"><i class="fa fa-times"></i> Close</button> 716 </div> 717 </div> 718 </div> 719 </div> 720 </div> 721 </div> 722 <div class="portfolio-modal modal fade" id="portfolioModal3" tabindex="-1" role="dialog" aria-hidden="true"> 723 <div class="modal-content"> 724 <div class="close-modal" data-dismiss="modal"> 725 <div class="lr"> 726 <div class="rl"> 727 </div> 728 </div> 729 </div> 730 <div class="container"> 731 <div class="row"> 732 <div class="col-lg-8 col-lg-offset-2"> 733 <div class="modal-body"> 734 <h2>Simulation</h2> 735 <hr class="star-primary"> 736 <img src="img/portfolio/host_diagram_scaled.png" class="img-responsive img-centered" alt=""> 737 <p> 738 Epidemiological and ecological systems may be complex, where multiple interactions need to be modelled explicitly. 739 My research focuses on using an array of simulation and modelling methodologies in order to capture the salient details of the system in study. 740 </p> 741 <h3> Publications </h3> 742 <ul class="list-group"> 743 <li class="list-group-item"> 744 <a href="https://doi.org/10.1016/j.epidem.2018.05.009">Kernel-density estimation and approximate Bayesian computation for flexible epidemiological model fitting in Python</a>.<br> 745 <b>Irvine MA</b>, and Hollingsworth TD 746 <i>Epidemics</i> (2018)<br>
747 Software: <a href="https://github.com/sempwn/ABCPRC">Github repository</a> 748 </li> 749 <li class="list-group-item"> 750 <a href="https://doi.org/10.1016/S2468-2667(18)30044-6">Distribution of take-home opioid antagonist kits during a synthetic opioid epidemic in British Columbia, Canada: a modelling study</a>.<br> 751 <b>Irvine MA</b>, Buxton JA, Otterstatter M, Balshaw R, Gustafson R, Tyndall M, Kendall P, Kerr Thomas, Gilbert M, and Coombs D 752 <i>The Lancet Public Health</i> (2018)<br> 753 News coverage: <a href="https://bc.ctvnews.ca/video?clipId=1373929">CTV news</a>, 754 <a href="http://www.cbc.ca/news/canada/british-columbia/take-home-naloxone-program-bc-1.4625201?cmp=rss">CBC news</a>, 755 <a href="http://vancouversun.com/health/local-health/making-naloxone-freely-available-reduced-fentanyl-overdose-deaths-in-b-c-study">Vancouver Sun</a>, 756 <a href="http://www.radionl.com/2018/04/18/6754/">Radio NL</a>, 757 <a href="http://www.theprovince.com/health/local-health/making+naloxone+freely+available+reduced+fentanyl/17305501/story.html">The Province</a>, 758 <a href="https://bc.ctvnews.ca/video?binId=1.1184759">CTV News</a> 759 </li> 760 <li class="list-group-item"> 761 <a href="https://doi.org/10.1098/rsif.2017.0849">A novel Bayesian approach to predicting reductions in HIV incidence following increased testing interventions among gay, bisexual and other men who have sex with men in Vancouver, Canada</a>.<br> 762 <b>Irvine MA</b>, Konrad BP, Balshaw R, Gilbert M, and Coombs D 763 <i>Roy. Soc. Interface</i> (2018)<br> 764 Blog post: <a href="https://medium.com/ubcscience/bayesian-analysis-sciences-best-attempt-at-fortune-telling-c862bdd290eb">Medium</a>. 765 </li> 766 <li class="list-group-item"> 767 <a href="http://dx.doi.org/10.1098/rspb.2017.2253">Understanding heterogeneities in mosquito-bite exposure and infection distributions for the elimination of lymphatic filariasis</a>.<br> 768 <b>Irvine MA</b>, Kazura JW, Hollingsworth TD, and Reimer LJ 769 <i>Proc. Roy. Soc. B</i> (2018)<br> 770 News coverage: <a href="http://www.lstmed.ac.uk/news-events/news/the-importance-of-heterogeneity-on-the-management-of-vector-borne-diseases">LSTM news</a>. 771 </li> 772 <li class="list-group-item"> 773 <a href="http://dx.doi.org/10.1038/s41598-017-17346-6">Conservation of pattern as a tool for inference on spatial snapshots in ecological data</a>.<br> 774 <b>Irvine MA</b>, Bull JC, Keeling MJ. 775 <i>Scientific Reports.</i> (2018) 776 </li> 777 <li class="list-group-item"> 778 <a href="http://dx.doi.org/10.1016/j.epidem.2017.02.006">Predicting lymphatic filariasis transmission and elimination dynamics using a multi-model ensemble framework</a>.<br> 779 Smith ME, Singh BK, <b>Irvine MA</b>, Wilma A. Stolk, Subramanian S, Hollingsworth TD, Michael E. 780 <i>Epidemics</i>. (2017) 781 </li> 782 <li class="list-group-item"> 783 <a href="http://dx.doi.org/10.1016/S1473-3099(16)30467-4">Effectiveness of a triple-drug regimen for global elimination of lymphatic filariasis: a modelling study</a>.<br> 784 <b>Irvine MA</b>, Stolk WA, Smith ME, Subramanian S, Singh BK, Weil GJ, Michael E, Hollingsworth TD. <i>The Lancet Infectious Diseases</i>. (2016) 785 <br> Outcomes: 786 <a href="http://www.who.int/lymphatic_filariasis/resources/9789241550161/en/"> 787 World Health Organisation guidelines on 788 alternative mass drug administration 789 regimens to eliminate lymphatic filariasis. 790 </a> 791 792 </li> 793 <li class="list-group-item"> 794 <a href="http://dx.doi.org/10.1098/rsif.2016.0463">Disease transmission promotes evolution of host spatial patterns</a>.<br> 795 <b>Irvine MA</b>, Bull JC, Keeling MJ. <i>J. R. Soc. Interface</i>. <b>13</b> 20160463 (2016) 796 </li> 797 <li class="list-group-item"> 798 <a href="http://dx.doi.org/10.1093/trstmh/trw024">Understanding the relationship between prevalence of microfilariae and antigenaemia using a model of lymphatic filariasis infection</a>.<br> 799 <b>Irvine MA</b>, Njenga SM, Gunawardena S, Wamae CN, Cano J, Brooker SJ, Hollingsworth TD. 800 <i>Transactions of The Royal Society of Tropical Medicine and Hygiene.</i> 801 <b>110</b>(2) pp. 118-24 (2016) 802 </li> 803 <li class="list-group-item"> 804 <a href="http://dx.doi.org/10.1186/s13071-015-1152-3">Modelling strategies to break transmission of lymphatic filariasis-aggregation, adherence and vector competence greatly alter elimination</a>.<br> 805 <b>Irvine MA</b>, Reimer LJ, Njenga SM, Gunawardena S, Kelly-Hope L, Bockarie M, Hollingsworth TD. 806 <i>Parasites & vectors.</i> 807 <b>8</b>(1) pp. 1 (2015) 808 </li> 809 <li class="list-group-item"> 810 <a href="http://dx.doi.org/10.1098/rsos.150519">Fractal measures of spatial pattern as a heuristic for return rate in vegetative systems</a>.<br> 811 <b>Irvine MA</b>, Jackson EL, Kenyon EJ, Cook KJ, Keeling MJ, Bull JC. <i>Royal Society open science</i>. <b>3</b>(3), pp. 150519 (2016) 812 </li> 813 814 </ul> 815 <button type="button" class="btn btn-default" data-dismiss="modal"><i class="fa fa-times"></i> Close</button> 816 </div> 817 </div> 818 </div> 819 </div> 820 </div> 821 </div> 822 <div class="portfolio-modal modal fade" id="portfolioModal4" tabindex="-1" role="dialog" aria-hidden="true"> 823 <div class="modal-content"> 824 <div class="close-modal" data-dismiss="modal"> 825 <div class="lr"> 826 <div class="rl"> 827 </div> 828 </div> 829 </div> 830 <div class="container"> 831 <div class="row"> 832 <div class="col-lg-8 col-lg-offset-2"> 833 <div class="modal-body"> 834 <h2>Modelling of public health interventions</h2> 835 <hr class="star-primary"> 836 <img src="img/portfolio/intervention.jpg" class="img-responsive img-centered" alt=""> 837 <p> 838 Public health comprises many complex interacting components both in terms of a disease 839 and its dynamics, as well as the public health system itself. Modelling of both an epidemic 840 and the healthcare system provides insight into the effectiveness of an intervention and 841 projected future outcomes. 842 </p> 843 <h3> Publications </h3> 844 <ul class="list-group"> 845 <li class="list-group-item"> 846 <a href="https://doi.org/10.1016/S2468-2667(18)30044-6">Modelling the combined impact of interventions in averting deaths during a syntheticâopioid overdose epidemic</a>.<br> 847 <b>Irvine MA</b>, Buxton JA, Otterstatter M, Balshaw R, Gustafson R, Tyndall M, Kendall P, Kerr Thomas, Gilbert M, and Coombs D 848 <i>Addiction</i> (2019)<br> 849 News coverage:<a href="https://www.cbc.ca/news/canada/british-columbia/bc-od-crisis-lives-saved-1.5163581">CBC news</a>, 850 <a href="https://www.theglobeandmail.com/canada/british-columbia/article-unsanctioned-overdose-prevention-site-opens-in-maple-ridge-renewing/">Globe and Mail</a>, 851 <a href="https://nationalpost.com/pmn/news-pmn/canada-news-pmn/rapid-response-to-b-c-s-overdose-crisis-saved-thousands-report-finds">National Post</a>, 852 <a href="https://www.straight.com/news/1252756/without-harm-reduction-overdoses-would-have-killed-thousands-more-bc-analysis-finds">Georgia Straight</a> 853 </li> 854 <li class="list-group-item"> 855 <a href="https://doi.org/10.1016/S2468-2667(18)30044-6">Distribution of take-home opioid antagonist kits during a synthetic opioid epidemic in British Columbia, Canada: a modelling study</a>.<br> 856 <b>Irvine MA</b>, Buxton JA, Otterstatter M, Balshaw R, Gustafson R, Tyndall M, Kendall P, Kerr Thomas, Gilbert M, and Coombs D 857 <i>The Lancet Public Health</i> (2018)<br> 858 News coverage: <a href="https://bc.ctvnews.ca/video?clipId=1373929">CTV news</a>, 859 <a href="http://www.cbc.ca/news/canada/british-columbia/take-home-naloxone-program-bc-1.4625201?cmp=rss">CBC news</a>, 860 <a href="http://vancouversun.com/health/local-health/making-naloxone-freely-available-reduced-fentanyl-overdose-deaths-in-b-c-study">Vancouver Sun</a>, 861 <a href="http://www.radionl.com/2018/04/18/6754/">Radio NL</a>, 862 <a href="http://www.theprovince.com/health/local-health/making+naloxone+freely+available+reduced+fentanyl/17305501/story.html">The Province</a>, 863 <a href="https://bc.ctvnews.ca/video?binId=1.1184759">CTV News</a> 864 </li> 865 <li class="list-group-item"> 866 <a href="https://doi.org/10.1098/rsif.2017.0849">A novel Bayesian approach to predicting reductions in HIV incidence following increased testing interventions among gay, bisexual and other men who have sex with men in Vancouver, Canada</a>.<br> 867 <b>Irvine MA</b>, Konrad BP, Balshaw R, Gilbert M, and Coombs D 868 <i>Roy. Soc. Interface</i> (2018)<br> 869 Blog post: <a href="https://medium.com/ubcscience/bayesian-analysis-sciences-best-attempt-at-fortune-telling-c862bdd290eb">Medium</a>. 870 </li> 871 <li class="list-group-item"> 872 <a href="http://dx.doi.org/10.1098/rspb.2017.2253">Understanding heterogeneities in mosquito-bite exposure and infection distributions for the elimination of lymphatic filariasis</a>.<br> 873 <b>Irvine MA</b>, Kazura JW, Hollingsworth TD, and Reimer LJ 874 <i>Proc. Roy. Soc. B</i> (2018)<br> 875 News coverage: <a href="http://www.lstmed.ac.uk/news-events/news/the-importance-of-heterogeneity-on-the-management-of-vector-borne-diseases">LSTM news</a>. 876 </li> 877 <li class="list-group-item"> 878 <a href="http://dx.doi.org/10.1016/S2352-3018(17)30123-6">Cost-effectiveness of screening for HIV in primary care: a health economics modelling analysis</a>.<br> 879 Baggaley RF, <b>Irvine MA</b>
879, Leber W, Cambiano V, Figueroa J, McMullen H, Anderson J, Santos AC , Terris-Prestholt F, Miners A, Hollingsworth TD, and Griffiths CJ 880 <i>The Lancet HIV</i> (2017)<br> 881 News coverage: <a href="http://www.bbc.com/news/health-40756196">BBC news</a>, <a href="http://www.telegraph.co.uk/science/2017/07/30/hiv-tests-should-offered-everyone-high-risk-areas-enroll-new/">The Telegraph</a>, 882 <a href="https://www.theguardian.com/society/2017/jul/30/hiv-tests-for-gps-new-patients-could-save-lives-and-money-says-study">The Guardian</a>, 883 <a href="https://www.newscientist.com/article/2142100/">New Scientist</a>, and 884 <a href="https://www.thetimes.co.uk/article/call-to-make-family-doctors-test-all-patients-for-hiv-p5qq50qzq">The Times</a>. 885 <br> 886 Outcomes: <a href="https://ecdc.europa.eu/sites/portal/files/documents/HIV-hepatitis-B-and-C-testing-public-health-guidance.pdf">Public health guidance on HIV, hepatitis B and C testing in the EU/EEA</a>. 887 </li> 888 <li class="list-group-item"> 889 <a href="http://dx.doi.org/10.1016/S1473-3099(16)30467-4">Effectiveness of a triple-drug regimen for global elimination of lymphatic filariasis: a modelling study</a>.<br> 890 <b>Irvine MA</b>, Stolk WA, Smith ME, Subramanian S, Singh BK, Weil GJ, Michael E, Hollingsworth TD. <i>The Lancet Infectious Diseases</i>. (2016) 891 <br> Outcomes: 892 <a href="http://www.who.int/lymphatic_filariasis/resources/9789241550161/en/"> 893 World Health Organisation guidelines on 894 alternative mass drug administration 895 regimens to eliminate lymphatic filariasis. 896 </a> 897 </li> 898 <li class="list-group-item"> 899 <a href="http://dx.doi.org/10.1093/trstmh/trw024">Understanding the relationship between prevalence of microfilariae and antigenaemia using a model of lymphatic filariasis infection</a>.<br> 900 <b>Irvine MA</b>, Njenga SM, Gunawardena S, Wamae CN, Cano J, Brooker SJ, Hollingsworth TD. 901 <i>Transactions of The Royal Society of Tropical Medicine and Hygiene.</i> 902 <b>110</b>(2) pp. 118-24 (2016) 903 </li> 904 <li class="list-group-item"> 905 <a href="http://dx.doi.org/10.1186/s13071-015-1152-3">Modelling strategies to break transmission of lymphatic filariasis-aggregation, adherence and vector competence greatly alter elimination</a>.<br> 906 <b>Irvine MA</b>, Reimer LJ, Njenga SM, Gunawardena S, Kelly-Hope L, Bockarie M, Hollingsworth TD. 907 <i>Parasites & vectors.</i> 908 <b>8</b>(1) pp. 1 (2015) 909 </li> 910 </ul> 911 <button type="button" class="btn btn-default" data-dismiss="modal"><i class="fa fa-times"></i> Close</button> 912 </div> 913 </div> 914 </div> 915 </div> 916 </div> 917 </div> 918 <div class="portfolio-modal modal fade" id="portfolioModal5" tabindex="-1" role="dialog" aria-hidden="true"> 919 <div class="modal-content"> 920 <div class="close-modal" data-dismiss="modal"> 921 <div class="lr"> 922 <div class="rl"> 923 </div> 924 </div> 925 </div> 926 <div class="container"> 927 <div class="row"> 928 <div class="col-lg-8 col-lg-offset-2"> 929 <div class="modal-body"> 930 <h2>Online Modelling Tools</h2> 931 <hr class="star-primary"> 932 <img src="img/portfolio/GUI_scaled.png" class="img-responsive img-centered" alt=""> 933 <p> 934 Modelling work can provide compelling evidence to policy-makers for the right decisions to make 935 when faced with challenges such as the control of an epidemic. Modelling tools, where a non-modelling expert 936 may enter certain scenarios and change some assumptions of the model allow users to interact directly with these tools 937 and provide a way of delivering relevant analysis directly to those who need it most. 938 </p> 939 <h3> Projects </h3> 940 <ul class="list-group"> 941 <li class="list-group-item"> 942 <p> Modelling a combination of interventions in the elimination of lymphatic filariasis.</p> 943 <p><a href="https://sempwn.github.io/TRANSFIL2/">TRANSFIL</a></p> 944 </li> 945 <li class="list-group-item"> 946 <p> Tutorial for exploring a simple epidemic model.</p> 947 <p><a href = "https://sempwn.github.io/epidemic">epidemic model</a></p> 948 </li> 949 <li class="list-group-item"> 950 <p> 951 Winning entry in <a href="http://news.fraserhealth.ca/News/January-2017/Fraser-Health-Hackathon-delivers-solutions-to-addr.aspx">Fraser Health Hackathon</a>. Dashboard for exploring analytics 952 in the number of emergency department visits in a given day for the Fraser Health Authority. 953 </p> 954 <p><a href="http://news.fraserhealth.ca/News/February-2017/Meet-the-Hackers-Team-Spurious-Correlations.aspx">Article</a></p> 955 <p><a href="https://sempwn.github.io/spurious-correlations-ai/">Dashboard</a></p> 956 </li> 957 <li class="list-group-item"> 958 <p> 959 Introduction to modelling and outbreak simulation tool created for the Science World 960 <a href="http://bccdcfoundation.org/blog/blog/2017/09/20/bccdc-foundation-partners-with-science-world-to-bring-bccdc-expert
960s-to-zombie-outbreak-event/">After Dark: Zombie Outbreak</a> 961 2017 event in partnership with the <a href="http://bccdcfoundation.org/">BCCDC foundation</a>. 962 </p> 963 <p><a href="https://sempwn.github.io/zombie-game/">Zombie outbreak modelling</a></p> 964 </li> 965 <li class="list-group-item"> 966 <p> 967 Introduction to vaccine dynamics created for the Science World 968 <a href="https://bccdcfoundation.org/bccdc-foundation-bccdc-and-science-world-after-dark-october-fun-events/">After Dark Murder Mystery 2019</a> 969 event in partnership with the <a href="http://bccdcfoundation.org/">BCCDC foundation</a>. 970 </p> 971 <p><a href="https://sempwn.github.io/vaccine-dynamics/">Vaccine modelling</a></p> 972 </li> 973 974 <li class="list-group-item"> 975 <p>Modelling of naloxone use and need by state in the US. Resulting model based on <a href="https://doi.org/10.1016/S2468-2667(21)00304-2">The Lancet Public Health study</a></p> 976 <p><a href="http://naloxoneneededtosave.org">How much naloxone is needed to save?</a></p> 977 </li> 978 </ul> 979 <h3> Related Publications </h3> 980 <ul class="list-group"> 981 <li class="list-group-item"> 982 <a href="http://dx.doi.org/10.1371/journal.pntd.0005206"> Making transmission models accessible to end-users: the example of TRANSFIL</a>.<br> 983 <b>Irvine MA</b>, Hollingsworth TD. <i>PLoS Neglected Tropical Diseases</i>. (2017) 984 </li> 985 </ul> 986 <button type="button" class="btn btn-default" data-dismiss="modal"><i class="fa fa-times"></i> Close</button> 987 </div> 988 </div> 989 </div> 990 </div> 991 </div> 992 </div> 993 <div class="portfolio-modal modal fade" id="portfolioModal6" tabindex="-1" role="dialog" aria-hidden="true"> 994 <div class="modal-content"> 995 <div class="close-modal" data-dismiss="modal"> 996 <div class="lr"> 997 <div class="rl"> 998 </div> 999 </div> 1000 </div> 1001 <div class="container"> 1002 <div class="row"> 1003 <div class="col-lg-8 col-lg-offset-2"> 1004 <div class="modal-body"> 1005 <h2>Pattern Formation</h2> 1006 <hr class="star-primary"> 1007 <img src="img/portfolio/pattern_formation_scaled.png" class="img-responsive img-centered" alt=""> 1008 <p> 1009 Complex systems in ecology and epidemiology can often produce striking spatial patterns 1010 from often simple underlying physical processes. These emergent behaviours can 1011 have a number of fascinating implications on the dynamics and stability of 1012 such systems. I have tried to understand the implications of 1013 some of these phenomena through my research in spatial ecology. 1014 </p> 1015 <h3> Related Publications </h3> 1016 <ul class="list-group"> 1017 <li class="list-group-item"> 1018 <a href="http://dx.doi.org/10.1038/s41598-017-17346-6">Conservation of pattern as a tool for inference on spatial snapshots in ecological data</a>.<br> 1019 <b>Irvine MA</b>, Bull JC, Keeling MJ. 1020 <i>Scientific Reports.</i> (2018) 1021 </li> 1022 <li class="list-group-item"> 1023 <a href="http://dx.doi.org/10.1098/rsif.2016.0463">Disease transmission promotes evolution of host spatial patterns</a>.<br> 1024 <b>Irvine MA</b>, Bull JC, Keeling MJ. <i>J. R. Soc. Interface</i>. <b>13</b> 20160463 (2016) 1025 </li> 1026 <li class="list-group-item"> 1027 <a href="http://dx.doi.org/10.1016/j.tpb.2015.12.001">Aggregation dynamics explain vegetation patch-size distributions</a>.<br> 1028 <b>Irvine MA</b>, Bull JC, Keeling MJ. <i>Theoretical population biology</i>. <b>108</b>(12), pp. 70-4 (2016) 1029 </li> 1030 <li class="list-group-item"> 1031 <a href="http://dx.doi.org/10.1098/rsos.150519">Fractal measures of spatial pattern as a heuristic for return rate in vegetative systems</a>.<br> 1032 <b>Irvine MA</b>, Jackson EL, Kenyon EJ, Cook KJ, Keeling MJ, Bull JC. <i>Royal Society open science</i>. <b>3</b>(3), pp. 150519 (2016) 1033 </li> 1034 </ul> 1035 <button type="button" class="btn btn-default" data-dismiss="modal"><i class="fa fa-times"></i> Close</button> 1036 </div> 1037 </div> 1038 </div> 1039 </div> 1040 </div> 1041 </div> 1042 1043 <!-- jQuery --> 1044
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