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165IT</span></a></div><div class="w-dropdown-list"><div class="w-dropdown-list-h"><a href="https://www.tgd.care/en/raw_materials/eugedin-complex/" class="w-dropdown-item smooth-scroll"><span class="w-dropdown-item-title">EN</span></a><a href="https://www.tgd.care/es/materias_primas/eugedin-complex/" class="w-dropdown-item smooth-scroll"><span class="w-dropdown-item-title">ES</span></a></div></div></div></div></div></div></div><div class="l-subheader for_hidden hidden"></div></header><main id="page-content" class="l-main" itemprop="mainContentOfPage"> 166 <section class="l-section wpb_row height_auto width_full with_shape"><div class="l-section-shape type_wave pos_bottom on_front" style="height:50px;color:#faf4ed"><svg xmlns="http://www.w3.org/2000/svg" viewBox="0 4 64 4" preserveAspectRatio="none" width="100%" height="100%"> 167 <path fill="currentColor" d="M64 6 C32 0 32 12 0 6 L0 8 L64 8 Z"/> 168</svg></div><div class="l-section-h i-cf"><div class="g-cols vc_row via_grid cols_3-2 laptops-cols_inherit tablets-cols_1 mobiles-cols_1 valign_top type_default stacking_default" style="--gap:5.7vw;"><div class="wpb_column vc_column_container us_custom_cfdd3aa0"><div class="vc_column-inner"><div class="w-separator size_large"></div><div class="w-image us_custom_3000a3fb has_ratio align_none"><div class="w-image-h"><div style="padding-bottom:38.0952%"></div><img decoding="async" width="1024" height="1024" src="https://www.tgd.care/wp-content/uploads/2024/12/Frame-4.svg" class="attachment-large size-large" alt="" loading="lazy" /></div></div><div class="w-separator size_custom" style="height:8px"></div><div class="wpb_text_column"><div class="wpb_wrapper"><p><strong>La naturale difesa del tuo benessere quotidiano</strong></p> 169<ul> 170<li>Soluzione innovativa per il potenziamento del sistema immunitario</li> 171<li>Attiva il processo di autofagia</li> 172<li>Progetto Europeo sviluppato in collaborazione con Eit Food</li> 173</ul> 174<p>Eugedin Complex®, una formulazione innovativa a base di olio essenziale di chiodi di garofano e germe di grano, naturalmente ricco di spermidina, è un ingrediente innovativo per rinforzare il sistema immunitario.</p> 175</div></div><div class="w-separator size_medium"></div><div class="w-tabs style_default switch_click accordion has_scrolling" style="--sections-title-size:inherit"><div class="w-tabs-sections titles-align_none icon_chevron cpos_right"><div class="w-tabs-section" id="w0c8"><button class="w-tabs-section-header" aria-controls="content-w0c8" aria-expanded="false"><div class="w-tabs-section-title">Benefici</div><div class="w-tabs-section-control"></div></button><div class="w-tabs-section-content" id="content-w0c8"><div class="w-tabs-section-content-h i-cf"><div class="wpb_text_column"><div class="wpb_wrapper"><p>L’innovazione e il vantaggio competitivo di Eugedin Complex® risiedono nell’effetto sinergico dei suoi ingredienti sul potenziamento del processo di autofagia dell’organismo, che consente alle cellule di combattere gli attacchi da parte dei virus. Questa attività antivirale si unisce all’attività antibatterica ed antiossidante dell’olio essenziale di chiodi di garofano. La formulazione del prodotto combina tre componenti principali: Estratto di Germe di Grano (Triticum aestivum) naturalmente arricchito in Spermidina, Olio Essenziale di Chiodi di Garofano (Syzygium aromaticum) e Vitamina D.</p> 176</div></div></div></div></div><div class="w-tabs-section" id="z2c6"><button class="w-tabs-section-header" aria-controls="content-z2c6" aria-expanded="false"><div class="w-tabs-section-title">Applicazioni</div><div class="w-tabs-section-control"></div></button><div class="w-tabs-section-content" id="content-z2c6"><div class="w-tabs-section-content-h i-cf"><div class="wpb_text_column"><div class="wpb_wrapper"><p>Eugedin Complex® è indicato per la formulazione di integratori alimentari per il potenziamento del sistema immunitario. Lo trovi in Eit Viral, <a href="https://www.tgd.care/eit-viral/">scopri di più</a>.</p> 177</div></div></div></div></div><div class="w-tabs-section" id="i4bd"><button class="w-tabs-section-header" aria-controls="content-i4bd" aria-expanded="false"><div class="w-tabs-section-title">Meccanismo d’azione</div><div class="w-tabs-section-control"></div></button><div class="w-tabs-section-content" id="content-i4bd"><div class="w-tabs-section-content-h i-cf"><div class="wpb_text_column"><div class="wpb_wrapper"><p>Prove in-vitro condotte dall’Università di Bologna, hanno confermato che i principi attivi contenuti in Eugedin Complex® stimolano il processo di l’autofagia in diversi tipi cellulari, comprese le cellule epiteliali intestinali, monociti, epiteliali bronchiali, endoteliali e neuronali umane. Per questo Eugedin Complex® è l’ingrediente ideale per il potenziamento delle naturali difese dell’organismo.</p> 178</div></div></div></div></div></div></div></div></div><div class="wpb_column vc_column_container"><div class="vc_column-inner"><div class="w-slider us_custom_0ccc3812 style_none fit_cover nav_none has_ratio count_3" style="--aspect-ratio: 3/4;"><div class="w-slider-h"><div class="royalSlider"><div class="rsContent"><a class="rsImg" data-rsw="855" data-rsh="775" href="https://www.tgd.care/wp-content/uploads/2024/12/grano-eugedin-complex.jpg">
178<span data-alt=""></span></a></div><div class="rsContent"><a class="rsImg" data-rsw="854" data-rsh="775" href="https://www.tgd.care/wp-content/uploads/2024/12/chiodi-di-garofano.jpg"><span data-alt=""></span></a></div><div class="rsContent"><a class="rsImg" data-rsw="854" data-rsh="775" href="https://www.tgd.care/wp-content/uploads/2024/12/eugedin-complex-polvere.jpg"><span data-alt=""></span></a></div></div><img decoding="async" src="https://www.tgd.care/wp-content/uploads/2024/12/grano-eugedin-complex.jpg" width="855" height="775" alt loading="lazy"></div><div class="w-slider-json" onclick='return {"autoScaleSlider":false,"addActiveClass":true,"loop":true,"fadeInLoadedSlide":false,"slidesSpacing":0,"imageScalePadding":0,"numImagesToPreload":2,"arrowsNav":false,"arrowsNavAutoHide":false,"transitionType":"fade","transitionSpeed":1300,"block":{"moveEffect":"none","speed":300},"thumbs":{"fitInViewport":false,"firstMargin":false,"spacing":4},"controlNavigation":"none","autoplay":{"enabled":true,"pauseOnHover":false,"delay":4000}}'></div></div></div></div></div></div></section><section class="l-section wpb_row height_huge with_shape"><div class="l-section-overlay" style="background:#faf4ed"></div><div class="l-section-shape type_wave pos_bottom" style="height:50px;"><svg xmlns="http://www.w3.org/2000/svg" viewBox="0 4 64 4" preserveAspectRatio="none" width="100%" height="100%"> 179 <path fill="currentColor" d="M64 6 C32 0 32 12 0 6 L0 8 L64 8 Z"/> 180</svg></div><div class="l-section-h i-cf"><div class="g-cols vc_row via_grid cols_2-1 laptops-cols_inherit tablets-cols_inherit mobiles-cols_1 valign_middle type_default stacking_default" style="--gap:5.1rem;"><div class="wpb_column vc_column_container"><div class="vc_column-inner"><div class="w-video us_custom_7cb69c13 align_none ratio_16x9 has_border_radius has_iframe"><div class="w-video-h"><iframe title="Youtube video player" src="//www.youtube.com/embed/B1nIPTnIeGg?autoplay=0&controls=0&origin=https://www.tgd.care&loop=0&mute=0" allowfullscreen="1" loading="lazy"></iframe></div><div class="w-video-icon" style="font-size:1.5rem;background:rgba(0,0,0,0.5);color:#fff"></div></div></div></div><div class="wpb_column vc_column_container"><div class="vc_column-inner"><div class="w-actionbox us_custom_6aa9e45b has_text_color color_light controls_bottom"><div class="w-actionbox-text"><h2 class="w-actionbox-title">Interessato?</h2></div><div class="w-actionbox-controls"><a class="w-btn us-btn-style_1" href="/contatti/"><span class="w-btn-label">Contattaci</span></a></div></div></div></div></div></div></section><section class="l-section wpb_row us_custom_c70c97eb height_large"><div class="l-section-overlay" style="background:var(--color-header-middle-bg)"></div><div class="l-section-h i-cf"><div class="g-cols vc_row via_grid cols_1 laptops-cols_inherit tablets-cols_inherit mobiles-cols_1 valign_top type_default stacking_default"><div class="wpb_column vc_column_container"><div class="vc_column-inner"><div class="wpb_text_column"><div class="wpb_wrapper"><h5><strong style="text-align: center; color: var(--color-header-middle-text-hover);">Hai domande?</strong><br /> 181Noi abbiamo le risposte</h5> 182</div></div><div class="w-separator size_medium"></div><div class="w-tabs style_default switch_click accordion type_togglable has_scrolling remove_indents" style="--sections-title-size:1.2rem"><div class="w-tabs-sections titles-align_none icon_chevron cpos_right"><div class="w-tabs-section has_text_color" id="o9c1" style="color:var(--color-header-middle-text);"><button class="w-tabs-section-header" aria-controls="content-o9c1" aria-expanded="false"><h6 class="w-tabs-section-title">A che cosa serve Eugedin Complex®?</h6><div class="w-tabs-section-control"></div></button><div class="w-tabs-section-content" id="content-o9c1"><div class="w-tabs-section-content-h i-cf"><div class="wpb_text_column"><div class="wpb_wrapper"><div class="toggle rel-p with-effect-d active-effect"> 183<div class="toggle-inner post-content"> 184<p>La formulazione del prodotto combina tre componenti principali:
184Estratto di Germe di Grano (Triticum aestivum) naturalmente ricco in Spermidina, Olio Essenziale di Chiodi di Garofano (Syzygium aromaticum Merr. et L.M. Perry) e Vitamina D. Lâinnovazione e il vantaggio competitivo di Eugedin Complex® risiedono nellâeffetto che i suoi ingredienti hanno sul sostegno delle difese immunitarie. Infatti, l’effetto balsamico ed antiossidante dell’olio essenziale di chiodi di garofano entra in sinergia con le proprietà immunomodulanti ed antinfiammatorie della vitamina D. Le proprietà di Eugedin Complex® sono sostenute da prove in vitro condotte dallâUniversità di Bologna (UniBO), che hanno confermato che i suoi ingredienti offrono un valido sostegno alle difese organiche.</p> 185</div> 186</div> 187</div></div></div></div></div><div class="w-tabs-section" id="bbe4"><button class="w-tabs-section-header" aria-controls="content-bbe4" aria-expanded="false"><h6 class="w-tabs-section-title">Che cos’è l’autofagia e come combatte i virus?</h6><div class="w-tabs-section-control"></div></button><div class="w-tabs-section-content" id="content-bbe4"><div class="w-tabs-section-content-h i-cf"><div class="wpb_text_column"><div class="wpb_wrapper"><div class="toggle rel-p with-effect-d1 active-effect"> 188<div class="toggle-inner post-content"> 189<p>Lâautofagia è il processo di degradazione naturale della cellula, che rimuove i componenti non necessari o disfunzionali attraverso un meccanismo regolato dipendente dal lisosoma. Così, le cellule del corpo eliminano tutto ciò che non è necessario o è danneggiato per facilitare, attraverso il riciclo, il reintegro dei nutrienti necessari alle funzioni vitali, allâomeostasi, allâinvecchiamento e allo sviluppo. Questo sistema, quindi, promuove lâeliminazione dei rifiuti potenzialmente nocivi, favorendo anche un apporto di energia alle cellule.<br /> 190Difetti nel processo autofagico sono stati collegati a varie malattie umane, tra cui la neurodegenerazione e il cancro, e lâinteresse per la modulazione dellâautofagia, come potenziale trattamento per queste malattie, è cresciuto rapidamente. à stato dimostrato che i virus appartenenti alla fam
190iglia Coronavirus sono in grado di bloccare i processi di autofagia cellulare per evitare la loro stessa degradazione. In effetti, esiste unâinterazione complessa e concomitante tra Coronavirus e autofagia, poiché questi virus sfruttano il meccanismo molecolare dellâautofagia evitando la deriva apoptotica protettiva e lâattivazione di risposte immunitarie cellulari innate. Infatti, non utilizzano la via secretoria biosintetica tipicamente utilizzata dai virus per lasciare le cellule infette ma sfruttano il traffico lisosomiale, inibiscono il meccanismo autofagico e usano unâesocitosi cellulare non convenzionale.</p> 191</div> 192</div> 193</div></div></div></div></div><div class="w-tabs-section" id="ne00"><button class="w-tabs-section-header" aria-controls="content-ne00" aria-expanded="false"><h6 class="w-tabs-section-title">Eugedin Complex® è un ingrediente sicuro?</h6><div class="w-tabs-section-control"></div></button><div class="w-tabs-section-content" id="content-ne00"><div class="w-tabs-section-content-h i-cf"><div class="wpb_text_column"><div class="wpb_wrapper"><div class="toggle rel-p with-effect-d2 active-effect"> 194<div class="toggle-inner post-content"> 195<p>Eugedin Complex® contiene Olio Essenziale di Chiodi di Garofano, Germe di Grano come fonte di Spermidina e Vitamina D. La dose giornaliera raccomandata per questo ingrediente è di 2 g/die. LâOlio Essenziale di Chiodi di Garofano è classificato come GRAS (Generally Recognized As Safe) dalla FDA ed è comunemente usato come agente aromatizzante. Gli studi clinici suggeriscono che non ci sono effetti collaterali noti della Spermidina.<br /> 196Il Regolamento di Esecuzione (UE) 2018/1023 della Commissione UE del 23 luglio 2018 specifica che il dosaggi
196o massimo di Spermidina in un integratore alimentare destinato alla popolazione adulta, escluse le donne in gravidanza e in allattamento, è di 6 mg/die. Pertanto, la dose raccomandata di Spermidina nella miscela (16 μg) è molto inferiore alla dose massima fissata dal Regolamento di Attuazione CE 2018/1023. Lâuso di Eugedin Complex® alla dose raccomandata è, pertanto, considerato sicuro.</p> 197</div> 198</div> 199<div class="toggle rel-p with-effect-d3 active-effect"> 200<div class="toggle-title bg-sz med no-mg"></div> 201</div> 202</div></div></div></div></div><div class="w-tabs-section" id="w035"><button class="w-tabs-section-header" aria-controls="content-w035" aria-expanded="false"><h6 class="w-tabs-section-title">Esiste un quadro normativo che copre gli ingredienti di Eugedin Complex®?</h6><div class="w-tabs-section-control"></div></button><div class="w-tabs-section-content" id="content-w035"><div class="w-tabs-section-content-h i-cf"><div class="wpb_text_column"><div class="wpb_wrapper"><div class="toggle rel-p with-effect-d3 active-effect"> 203<div class="toggle-inner post-content"> 204<p>Esiste un ampio quadro normativo europeo che copre gli ingredienti del prodotto.<br /> 205Il General Food Law Regulation (Regolamento CE 178/2002 del Parlamento Europeo e del Consiglio) ha stabilito il principio e prevedeva la creazione di un organismo indipendente denominato Autorità Europea per la Sicurezza Alimentare (EFSA) con il compito specifico di fornire pareri scientifici basati sulla valutazione degli effetti benefici sulla salute e dei rischi associati allâassunzione di cibo. Gli ingredienti del prodotto Eugedin Complex®, in particolare spermidina ed olio essenziale di Chiodi di Garofano, rientrano in due ampie categorie di leggi dellâUE che ne regolano lâuso e le specifiche. La spermidina è considerata un nuovo alimento ed è quindi regolamentata dalla serie di regolamenti e regolamenti di attuazione dellâUE sui nuovi alimenti. LâOlio Essenziale di Chiodi di Garofano è regolamentato dalle normative sui botanicals che fanno riferimento all’Allegato 1 al DM 10 agosto 2018. Tuttavia, per quanto riguarda in particolare la spermidina e lâOlio Essenziale ei Chiodi di Garofano, la Commissione Europea ha recepito due Regolamenti:<br /> 206Regolamento di esecuzione n. 141/2014 della Commissione, del 13 febbraio 2014, che modifica il regolamento di esecuzione (UE) n. 540/2011 per quanto riguarda le condizioni di approvazione della sostanza attiva oli vegetali/olio di chiodi di garofano.<br /> 207Regolamento di esecuzione (UE) 2020/443 della Commissione, del 25 marzo 2020, che autorizza la modifica delle specifiche del nuovo prodotto alimentare estratto di germe di grano ricco di spermidina (Triticum aestivum) ai sensi del regolamento (UE) 2015/2283 del Parlamento europeo e del Consiglio e che modifica il regolamento di esecuzione (UE) 2017/2470 della Commissione.</p> 208</div> 209</div> 210<div class="toggle rel-p with-effect-d4 active-effect"> 211<div class="toggle-title bg-sz med no-mg"></div> 212</div> 213</div></div></div></div></div><div class="w-tabs-section" id="z223"><button class="w-tabs-section-header" aria-controls="content-z223" aria-expanded="false"><h6 class="w-tabs-section-title">Da dove vengono gli ingredienti di Eugedin Complex®?</h6><div class="w-tabs-section-control"></div></button><div class="w-tabs-section-content" id="content-z223"><div class="w-tabs-section-content-h i-cf"><div class="wpb_text_column"><div class="wpb_wrapper"><p>Il germe di grano crudo proviene da Molino Naldoni, unâazienda molitoria italiana con 320 anni di storia ed elevati standard produttivi. Lâolio essenziale di chiodi di garofano proviene dallâIndonesia. Le materie prime vengono tutte lavorate in Italia.</p> 214</div></div></div></div></div><div class="w-tabs-section" id="y435"><button class="w-tabs-section-header" aria-controls="content-y435" aria-expanded="false"><h6 class="w-tabs-section-title">Come viene prodotto Eugedin Complex®?</h6><div class="w-tabs-section-control"></div></button><div class="w-tabs-section-content" id="content-y435"><div class="w-tabs-section-content-h i-cf"><div class="wpb_text_column"><div class="wpb_wrapper"><div class="toggle rel-p with-effect-d active-effect"> 215<div class="toggle-inner post-content"> 216<p>– Il germe di grano viene lavorato: essiccato, pressato e macinato in polvere;<br /> 217– Lâolio essenziale di chiodi di garofano viene aggiunto e mescolato alla polvere di germe di grano;<br /> 218– La polvere costituita ora sia da spermidina che da olio essenziale di chiodi di garofano, viene essiccata ed addizionata con vitamina D;<br /> 219– La miscela finale in polvere viene confezionata ed è pronta per essere venduta come Eugedin Complex®.</p> 220</div> 221</div> 222</div></div></div></div></div></div></div><div class="w-separator size_medium"></div></div></div></div></div></section><section class="l-section wpb_row height_small color_alternate"><div class="l-section-overlay" style="background:var(--color-content-bg-alt)"></div><div class="l-section-h i-cf"><div class="g-cols vc_row via_grid cols_3-1 laptops-cols_2-1 tablets-cols_inherit mobiles-cols_1 valign_middle type_default"><div class="wpb_column vc_column_container"><div class="vc_column-inner"><h5 class="w-text"><span class="w-text-h"><span class="w-text-value">Scopri l’integratore relativo</span></span></h5></div></div><div class="wpb_column vc_column_container"><div class="vc_column-inner"><div class="w-btn-wrapper default_align_right laptops_align_right tablets_align_right mobiles_align_none"><a class="w-btn us-btn-style_1 icon_atleft text_none" aria-label="Button" href="/eit-viral/"><i class="fas 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