https://www.refine.bio/_next/static/chunks/pages/about-0b63828227ebc788.js

1(self.webpackChunk_N_E=self.webpackChunk_N_E||[]).push([[521],{3261:function(e,t,r){"use strict";r.d(t,{V:function(){return h}});var n=r(9499),i=r(4730),a=r(975),o=r(253),s=r(5893),l=["boxPadding","boxWidth","children","header","marginBottom"];function c(e,t){var r=Object.keys(e);if(Object.getOwnPropertySymbols){var n=Object.getOwnPropertySymbols(e);t&&(n=n.filter(function(t){return Object.getOwnPropertyDescriptor(e,t).enumerable})),r.push.apply(r,n)}return r}function d(e){for(var t=1;t<arguments.length;t++){var r=null!=arguments[t]?arguments[t]:{};t%2?c(Object(r),!0).forEach(function(t){(0,n.Z)(e,t,r[t])}):Object.getOwnPropertyDescriptors?Object.defineProperties(e,Object.getOwnPropertyDescriptors(r)):c(Object(r)).forEach(function(t){Object.defineProperty(e,t,Object.getOwnPropertyDescriptor(r,t))})}return e}var h=function(e){var t=e.boxPadding,r=e.boxWidth,n=void 0===r?"100%":r,c=e.children,h=e.header,u=e.marginBottom,g=void 0===u?"basex7":u,p=(0,i.Z)(e,l),m=(0,o.F)().setResponsive;return(0,s.jsxs)(a.x,d(d({align:m("start","center")},p),{},{children:[h,(0,s.jsx)(a.x,{width:n,margin:{bottom:m(g,"basex7","basex12")},children:(0,s.jsx)(a.x,{align:"center",background:"white",elevation:"xlarge",pad:void 0===t?{}:t,round:"xsmall",width:n,children:c})})]}))}},1696:function(e,t){"use strict";t.Z=function(e){var t=arguments.length>1&&void 0!==arguments[1]?arguments[1]:2;if(0===e)return"0 Bytes";var r=t<=0?0:t,n=Math.floor(Math.log(e)/Math.log(1024));return"".concat(parseFloat((e/Math.pow(1024,n)).toFixed(r))," ").concat(["Bytes","KB","MB","GB","TB","PB","EB","ZB","YB"][n])}},3639:function(e,t){"use strict";t.Z=function(e){return e?new Intl.NumberFormat("en-US",{style:"decimal"}).format(e):null}},6849:function(e,t,r){"use strict";r.r(t),r.d(t,{default:function(){return B}});var n=r(975),i=r(253),a=r(3121),o=r(9521),s=r(6432),l=r(4854),c=r(6034),d=r(7208),h=r(9419),u=r(5893),g=(0,o.default)(a.n).withConfig({displayName:"AboutCCDL__PRubik",componentId:"sc-1mc4wv7-0"})(["font-family:'Rubik',sans-serif;"]),p=function(){var e=(0,i.F)(),t=e.viewport,r=e.setResponsive;return(0,u.jsxs)(l.e,{border:{color:"gray-shade-5",side:"top",size:"large"},pad:{horizontal:r("none","medium","large"),top:r("basex7","basex7","basex9"),bottom:r("basex7","basex7","basex12")},children:[(0,u.jsx)(c.X,{justify:"center",margin:{bottom:"xlarge"},children:(0,u.jsxs)(g,{size:"xlarge",textAlign:"center",children:["Created by the Childhood Cancer Data Lab (CCDL), powered by Alex’s Lemonade Stand ","large"===t&&(0,u.jsx)("br",{})," Foundation, this endeavor is harnessing the power of big data to accelerate the pace of potential cures."]})}),(0,u.jsx)(c.X,{align:"center",justify:"center",margin:{bottom:"basex7"},children:(0,u.jsx)(n.x,{background:{image:"url(CCDL-x-ALSF.svg)",position:"center",repeat:"no-repeat",size:"contain"},width:"453px",height:"107px",children:(0,u.jsx)(d.o,{children:"Childhood Cancer Data Lab powered by Alex's Lemonade Stand Foundation"})})}),(0,u.jsxs)(c.X,{align:"center",justify:r("start","around"),elevation:"xlarge",pad:{horizontal:r("medium","medium","large"),vertical:r("medium","xlarge")},round:"8px",children:[(0,u.jsx)(n.x,{justify:"center",width:r("auto","500px"),children:(0,u.jsx)(g,{size:r("large","xlarge"),children:"Donate today to support the CCDL’s efforts to give researchers the tools to create a healthier, more prosperous future for kids fighting cancer and beyond."})}),(0,u.jsx)(n.x,{justify:"center",margin:{top:r("medium","none")},width:r("100%","auto"),children:(0,u.jsx)(s.z,{href:h.Ok.ccdl_donate,label:"Donate Now",large:!0,primary:!0,responsive:!0,uppercase:!0,rel:"noopener noreferrer",target:"_blank"})})]})]})},m=r(8087),x=r(7670),b=r(6816),f=r(1696),j=r(3639),v=r(3261),y=function(e){var t=e.count,r=e.text,a=(0,i.F)().setResponsive;return(0,u.jsxs)(n.x,{align:"center",margin:{top:a("medium","none")},children:[(0,u.jsx)(m.x,{color:"brand",margin:{bottom:a("xsmall","small")},size:a("xxxlarge","xxxxlarge"),children:t}),(0,u.jsx)(m.x,{size:a("medium","large"),textAlign:"center",children:r})]})},w=function(){var e=(0,i.F)(),t=e.viewport,r=e.setResponsive;return(0,u.jsxs)(x.X,{color:"white",level:1,margin:{bottom:"large"},size:r("large","xlarge"),style:{textShadow:"0 3px 19px rgba(0,0,0,.5)"},textAlign:"center",weight:"500",children:["Fighting childhood cancer, ","small"!==t&&(0,u.jsx)("br",{}),"thousands of datasets at a time"]})},O=function(){var e=(0,i.F)().setResponsive,t={availableSamples:(0,b.Z)(h.Fs.statsAbout.samples_available),processedExperiment:(0,j.Z)(h.Fs.statsAbout.experiments_processed),supportedOrganism:(0,b.Z)(h.Fs.statsAbout.supported_organisms),totalSize:(0,f.Z)(h.Fs.statsAbout.total_size_in_bytes,1)};return(0,u.jsx)(l.e,{children:(0,u.jsxs)(v.V,{header:(0,u.jsx)(w,{}),boxPadding:{horizontal:e("small","xlarge"),vertical:e("small","large")},marginBottom:"xlarge",children:[(0,u.jsxs)(x.X,{level:2,margin:{bottom:e("none","xlarge")},size:e("small","large"),textAlign:"center",children:["refine.bio has harmonized over ",t.processedExperiment," gene expression experiments"]}),(0,u.jsxs)(n.x,{align:e("center","start"),direction:e("column","row"),justify:"between",width:"100%",children:[(0,u.jsx)(y,{count:t.availableSamples,text:"".concat(t.availableSamples," samples available")}),(0,u.jsx)(y,{count:t.supportedOrganism,text:"Support for ".concat(t.supp

1ortedOrganism," organisms")}),(0,u.jsx)(y,{count:t.totalSize,text:"".concat(t.totalSize," of raw data processed")})]})]})})},z=r(9499),P=r(4730),_=r(3586),F=["align","direction","heading","body","img"];function S(e,t){var r=Object.keys(e);if(Object.getOwnPropertySymbols){var n=Object.getOwnPropertySymbols(e);t&&(n=n.filter(function(t){return Object.getOwnPropertyDescriptor(e,t).enumerable})),r.push.apply(r,n)}return r}function k(e){for(var t=1;t<arguments.length;t++){var r=null!=arguments[t]?arguments[t]:{};t%2?S(Object(r),!0).forEach(function(t){(0,z.Z)(e,t,r[t])}):Object.getOwnPropertyDescriptors?Object.defineProperties(e,Object.getOwnPropertyDescriptors(r)):S(Object(r)).forEach(function(t){Object.defineProperty(e,t,Object.getOwnPropertyDescriptor(r,t))})}return e}var D=function(e){var t=e.align,r=void 0===t?"end":t,n=e.direction,o=void 0===n?"row":n,s=e.heading,l=e.body,d=e.img,h=d.url,g=d.position,p=(0,P.Z)(e,F),m=(0,i.F)().setResponsive;return(0,u.jsxs)(c.X,k(k({direction:m("column-reverse",o)},p),{},{children:[(0,u.jsxs)(_.s,{align:m("center","start"),justify:m("start","center"),children:[(0,u.jsx)(x.X,{level:2,margin:{bottom:"small"},size:m("small","large"),children:s}),(0,u.jsx)(a.n,{children:l})]}),(0,u.jsx)(_.s,{align:m("center",r),"aria-hidden":!0,basis:m("auto","full"),background:{image:"url('".concat(h,"')"),position:m("center",g),repeat:"no-repeat",size:"contain"},height:m("195px","240px","300px"),margin:{bottom:"small"},width:"100%"})]}))},C=function(){var e=(0,i.F)().setResponsive;return(0,u.jsxs)(u.Fragment,{children:[(0,u.jsx)(c.X,{children:(0,u.jsx)(D,{heading:"Saving Time to Save Lives",body:"When childhood cancer researchers download transcriptome data  (the collection of RNA molecules in a cell), each set can seem like its  own language. Different studies use distinct technologies to collect the  same type of data, and each technology has its own language. Researchers  can spend up to 30% of their time translating these datasets into something  they can use. This cumbersome process takes away valuable resources that  could be spent in the lab discovering cutting-edge treatments and cures.  refine.bio is here to fix that.",img:{url:"illustration-saving-time.svg",position:"center right"}})}),(0,u.jsx)(c.X,{margin:{top:e("xlarge","basex12")},children:(0,u.jsx)(D,{align:"start",direction:"row-reverse",heading:"One Language, One Repository",body:"It’s the Rosetta Stone for the vast amount of publicly available childhood  cancer data. It’s the first project of its kind to harmonize this information across  many different technologies into one universal repository. Now researchers can pull  from this massive dataset, saving precious time.",img:{url:"illustration-one-repo.svg",position:"center left"}})}),(0,u.jsx)(c.X,{margin:{top:e("xlarge","basex12")},children:(0,u.jsx)(D,{heading:"Better Medicine Through Machine Learning",body:"With the power of machine learning and the rich collection of data in refine.bio,  researchers have the potential to extract more information about the biology of a patient’s  sample. In turn researchers will be able to better classify patients and identify what types  of treatments might be most effective on a case-by-case basis, further enhancing the  burgeoning field of precision medicine.",img:{url:"illustration-network-bottle.svg",position:"center right"}})})]})},B=function(){var e=(0,i.F)().setResponsive;return(0,u.jsxs)(n.x,{pad:{top:"basex10",bottom:e("basex7","basex7","basex9")},children:[(0,u.jsx)(l.e,{pad:{horizontal:e("none","medium","basex15")},children:(0,u.jsx)(O,{})}),(0,u.jsx)(l.e,{pad:{horizontal:e("medium","medium","basex15")},children:(0,u.jsx)(C,{})}),(0,u.jsx)(l.e,{pad:{horizontal:e("medium","medium","basex15")},children:(0,u.jsx)(p,{})})]})}},512:function(e,t,r){(window.__NEXT_P=window.__NEXT_P||[]).push(["/about",function(){return r(6849)}])}},function(e){e.O(0,[774,888,179],function(){return e(e.s=512)}),_N_E=e.O()}]);