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373 374 375<body> 376 <div> 377 <table id="mytable" class="table-style1" cellspacing="0" width="100%"> 378<thead> 379 <tr> 380 <th>Year</th> 381 <th>Author</th> 382 <th>Title</th> 383 <th>Ribozyme name</th> 384 <th>Description</th> 385 <th>Journal</th> 386 </tr> 387</thead> 388 <tr> 389 <td>2004</td> 390 <td>Adams, P. L., M. R. Stahley, A. B. Kosek, J. Wang and S. A. Strobel </td> 391 <td>Crystal structure of a self-splicing group I intron with both exons.</td> 392 <td><a href="https://www.ribocentre.org/docs/groupI.html" target="_blank"><b> Group I self-splicing intron</b></a></td> 393 <td>Crystal structure of <em>Azoarcus</em> group I intron with both exons</td> 394 <td><a href="https://www.ncbi.nlm.nih.gov/pubmed/15175762" target="_blank"><b> Nature 430 (6995): 45-50.</b></a></td> 395 </tr> 396 <tr> 397 <td>2004</td> 398 <td>Guo, F., A. R. Gooding and T. R. Cech </td> 399 <td>Structure of the <em>Tetrahymena</em> ribozyme: base triple sandwich and metal ion at the active site.</td> 400 <td><a href="https://www.ribocentre.org/docs/groupI.html" target="_blank"><b> Group I self-splicing intron</b></a></td> 401 <td>Crystal structure of an active <em>Tetrahymena</em> ribozyme</td> 402 <td><a href="https://www.ncbi.nlm.nih.gov/pubmed/15525509" target="_blank"><b> Mol Cell 16 (3): 351-62.</b></a></td> 403 </tr> 404 <tr> 405 <td>2005</td> 406 <td>Golden, B. L., H. Kim and E. Chase </td> 407 <td>Crystal structure of a phage Twort group I ribozyme-product complex.</td> 408 <td><a href="https://www.ribocentre.org/docs/groupI.html" target="_blank"><b> Group I self-splicing intron</b></a></td> 409 <td>Crystal structure of phage Twort group I ribozyme-product complex</td> 410 <td><a href="https://www.ncbi.nlm.nih.gov/pubmed/15580277" target="_blank"><b> Nat Struct Mol Biol 12 (1): 82-9.</b></a></td> 411 </tr> 412 <tr> 413 <td>2005</td> 414 <td>Stahley, M. R. and S. A. Strobel </td> 415 <td>Structural evidence for a two-metal-ion mechanism of group I intron splicing.</td> 416 <td><a href="https://www.ribocentre.org/docs/groupI.html" target="_blank"><b> Group I self-splicing intron</b></a></td> 417 <td>Crystal structure of a catalytically active <em>Azoarcus</em> group I intron splicing intermediate</td> 418 <td><a href="https://www.ncbi.nlm.nih.gov/pubmed/16141079" target="_blank"><b> Science 309 (5740): 1587-90.</b></a></td> 419 </tr> 420 <tr> 421 <td>2021</td> 422 <td>Su, Z., K. Zhang, K. Kappel, S. Li, M. Z. Palo, G. D. Pintilie, R. Rangan, B. Luo, Y. Wei, R. Das and W. Chiu </td> 423 <td>Cryo-EM structures of full-length <em>Tetrahymena</em> ribozyme at 3.1 A resolution.</td> 424 <td><a href="https://www.ribocentre.org/docs/groupI.html" target="_blank"><b> Group I self-splicing intron</b></a></td> 425 <td>Cryo-EM structures of full-length <em>Tetrahymena</em> ribozyme</td> 426 <td><a href="https://www.ncbi.nlm.nih.gov/pubmed/34381213" target="_blank"><b> Nature 596 (7873): 603-607.</b></a></td> 427 </tr> 428 <tr> 429 <td>1989</td> 430 <td>Williamson, C. L., N. M. Desai and J. M. Burke </td> 431 <td>Compensatory mutations demonstrate that P8 and P6 are RNA secondary structure elements important for processing of a group I intron.</td> 432 <td><a href="https://www.ribocentre.org/docs/groupI.html" target="_blank"><b> Group I self-splicing intron</b></a></td> 433 <td>Verify the existence and importance of P6, P8</td> 434 <td><a href="https://www.ncbi.nlm.nih.gov/pubmed/2915927" target="_blank"><b> Nucleic Acids Res 17 (2): 675-89.</b></a></td> 435 </tr> 436 <tr> 437 <td>1989</td> 438 <td>Doudna, J. A., B. P. Cormack and J. W. Szostak </td> 439 <td>RNA structure, not sequence, determines the 5' splice-site specificity of a group I intron.</td> 440 <td><a href="https://www.ribocentre.org/docs/groupI.html" target="_blank"><b> Group I self-splicing intron</b></a></td> 441 <td>Conserved UG is an important recognition element for determining guanosine attack sites</td> 442 <td><a href="https://www.ncbi.nlm.nih.gov/pubmed/2678103" target="_blank"><b> Proc Natl Acad Sci U S A 86 (19): 7402-6.</b></a></td> 443 </tr> 444 <tr> 445 <td>1989</td> 446 <td>Flor, P. J., J. B. Flanegan and T. R. Cech </td> 447 <td>A conserved base pair within helix P4 of the <em>Tetrahymena</em> ribozyme helps to form the tertiary structure required for self-splicing.</td> 448 <td><a href="https://www.ribocentre.org/docs/groupI.html" target="_blank"><b> Group I self-splicing intron</b></a></td> 449 <td>The conserved base pair C109-G212 in P4 contributes to the tertiary structure required for self-splicing</td> 450 <td><a href="https://www.ncbi.nlm.nih.gov/pubmed/2684642" target="_blank"><b> EMBO J 8 (11): 3391-9.</b></a></td> 451 </tr> 452 <tr> 453 <td>1982</td> 454 <td>Kruger, K., P. J. Grabowski, A. J. Zaug, J. Sands, D. E. Gottschling and T. R. Cech </td> 455 <td>Self-splicing RNA: autoexcision and autocyclization of the ribosomal RNA intervening sequence of <em>Tetrahymena</em>
455.</td> 456 <td><a href="https://www.ribocentre.org/docs/groupI.html" target="_blank"><b> Group I self-splicing intron</b></a></td> 457 <td>Discovery</td> 458 <td><a href="https://www.ncbi.nlm.nih.gov/pubmed/6297754" target="_blank"><b> Cell 31 (1): 147-57.</b></a></td> 459 </tr> 460 <tr> 461 <td>1982</td> 462 <td>Davies, R. W., R. B. Waring, J. A. Ray, T. A. Brown and C. Scazzocchio </td> 463 <td>Making ends meet: a model for RNA splicing in fungal mitochondria.</td> 464 <td><a href="https://www.ribocentre.org/docs/groupI.html" target="_blank"><b> Group I self-splicing intron</b></a></td> 465 <td>Determination of shared secondary structure</td> 466 <td><a href="https://www.ncbi.nlm.nih.gov/pubmed/6757759" target="_blank"><b> Nature 300 (5894): 719-24.</b></a></td> 467 </tr> 468 <tr> 469 <td>1986</td> 470 <td>Zaug, A. J. and T. R. Cech </td> 471 <td>The intervening sequence RNA of <em>Tetrahymena</em> is an enzyme.</td> 472 <td><a href="https://www.ribocentre.org/docs/groupI.html" target="_blank"><b> Group I self-splicing intron</b></a></td> 473 <td>The intervening sequence RNA of <em>Tetrahymena</em> is an enzyme</td> 474 <td><a href="https://www.ncbi.nlm.nih.gov/pubmed/3941911" target="_blank"><b> Science 231 (4737): 470-5.</b></a></td> 475 </tr> 476 <tr> 477 <td>1988</td> 478 <td>Price, J. V. and T. R. Cech </td> 479 <td>Determinants of the 3' splice site for self-splicing of the <em>Tetrahymena</em> pre-rRNA.</td> 480 <td><a href="https://www.ribocentre.org/docs/groupI.html" target="_blank"><b> Group I self-splicing intron</b></a></td> 481 <td>ÏG is closely related to the choice of 3' splice site</td> 482 <td><a href="https://www.ncbi.nlm.nih.gov/pubmed/3209068" target="_blank"><b> Genes Dev 2 (11): 1439-47.</b></a></td> 483 </tr> 484 <tr> 485 <td>1990</td> 486 <td>Michel, F. and E. Westhof </td> 487 <td>Modelling of the three-dimensional architecture of group I catalytic introns based on comparative sequence analysis.</td> 488 <td><a href="https://www.ribocentre.org/docs/groupI.html" target="_blank"><b> Group I self-splicing intron</b></a></td> 489 <td>3D models of group I intron based on comparative sequence analysis</td> 490 <td><a href="https://www.ncbi.nlm.nih.gov/pubmed/2258934" target="_blank"><b> J Mol Biol 216 (3): 585-610.</b></a></td> 491 </tr> 492 <tr> 493 <td>1996</td> 494 <td>Cate, J. H., A. R. Gooding, E. Podell, K. Zhou, B. L. Golden, C. E. Kundrot, T. R. Cech and J. A. Doudna </td> 495 <td>Crystal structure of a group I ribozyme domain: principles of RNA packing.</td> 496 <td><a href="https://www.ribocentre.org/docs/groupI.html" target="_blank"><b> Group I self-splicing intron</b></a></td> 497 <td>Crystal structure of <em>Tetrahymena</em> P4-P6 domain</td> 498 <td><a href="https://www.ncbi.nlm.nih.gov/pubmed/8781224" target="_blank"><b> Science 273 (5282): 1678-85.</b></a></td> 499 </tr> 500 <tr> 501 <td>1998</td> 502 <td>Golden, B. L., A. R. Gooding, E. R. Podell and T. R. Cech </td> 503 <td>A preorganized active site in the crystal structure of the <em>Tetrahymena</em> ribozyme.</td> 504 <td><a href="https://www.ribocentre.org/docs/groupI.html" target="_blank"><b> Group I self-splicing intron</b></a></td> 505 <td>Crystal structure of an engineered, active <em>Tetrahymena</em> ribozyme at 5.0 Ã resolution</td> 506 <td><a href="https://www.ncbi.nlm.nih.gov/pubmed/9841391" target="_blank"><b> Science 282 (5387): 259-64.</b></a></td> 507 </tr> 508 <tr> 509 <td>2011</td> 510 <td>Benz-Moy, T. L. and D. Herschlag </td> 511 <td>Structure-function analysis from the outside in: long-range tertiary contacts in RNA exhibit distinct catalytic roles.</td> 512 <td><a href="https://www.ribocentre.org/docs/groupI.html" target="_blank"><b> Group I self-splicing intron</b></a></td> 513 <td>Long-range tertiary contacts in RNA exhibit distinct catalytic roles</td> 514 <td><a href="https://www.ncbi.nlm.nih.gov/pubmed/21815635" target="_blank"><b> Biochemistry 50 (40): 8733-55.</b></a></td> 515 </tr> 516 <tr> 517 <td>2022</td> 518 <td>Liu, D., F. A. Thelot, J. A. Piccirilli, M. Liao and P. Yin </td> 519 <td>Sub-3-A cryo-EM structure of RNA enabled by engineered homomeric self-assembly.</td> 520 <td><a href="https://www.ribocentre.org/docs/groupI.html" target="_blank"><b> Group I self-splicing intron</b></a></td> 521 <td><em>Tetrahymena</em> group I intron at 2.98-Ã resolution overall (2.85 Ã for the core)</td> 522 <td><a href="https://www.ncbi.nlm.nih.gov/pubmed/35501384" target="_blank"><b> Nat Methods 19 (5): 576-585.</b></a></td> 523 </tr> 524 <tr> 525 <td>1994</td> 526 <td>
526Damberger, S. H. and R. R. Gutell </td> 527 <td>A comparative database of group I intron structures.</td> 528 <td><a href="https://www.ribocentre.org/docs/groupI.html" target="_blank"><b> Group I self-splicing intron </b></a></td> 529 <td>Comparative database</td> 530 <td><a href="https://www.ncbi.nlm.nih.gov/pubmed/7937050" target="_blank"><b> Nucleic Acids Res 22 (17): 3508-10.</b></a></td> 531 </tr> 532 <tr> 533 <td>2008</td> 534 <td>Zhou, Y., C. Lu, Q. J. Wu, Y. Wang, Z. T. Sun, J. C. Deng and Y. Zhang </td> 535 <td>GISSD: Group I Intron Sequence and Structure Database.</td> 536 <td><a href="https://www.ribocentre.org/docs/groupI.html" target="_blank"><b> Group I self-splicing intron </b></a></td> 537 <td>Sequence and structure database</td> 538 <td><a href="https://www.ncbi.nlm.nih.gov/pubmed/17942415" target="_blank"><b> Nucleic Acids Res 36 (Database issue): D31-7.</b></a></td> 539 </tr> 540 <tr> 541 <td>2009</td> 542 <td>Vicens, Q. and T. R. Cech </td> 543 <td>A natural ribozyme with 3',5' RNA ligase activity.</td> 544 <td><a href="https://www.ribocentre.org/docs/nature-ribozyme.html" target="_blank"><b>A natural ribozyme with 3',5' RNA ligase activity</b></a></td> 545 <td>Discovery</td> 546 <td><a href="https://www.ncbi.nlm.nih.gov/pubmed/19125157" target="_blank"><b> Nat Chem Biol 5(2): 97-9.</b></a></td> 547 </tr> 548 <tr> 549 <td>2004</td> 550 <td>J. Proudfoot and A. Akoulitchev </td> 551 <td>Autocatalytic RNA cleavage in the human beta-globin pre-mRNA promotes transcription termination.</td> 552 <td><a href="https://www.ribocentre.org/docs/CoTC.html" target="_blank"><b>CoTC ribozyme(Beta-globin co-transcriptional cleavage ribozyme)</b></a></td> 553 <td>Discovery that the CoTC process in the human beta-globin gene involves an RNA self-cleaving activity</td> 554 <td><a href="https://www.ncbi.nlm.nih.gov/pubmed/15565159" target="_blank"><b> Nature 432(7016): 526-530.</b></a></td> 555 </tr> 556 <tr> 557 <td>2006</td> 558 <td>Salehi-Ashtiani, K., A. Luptak, A. Litovchick and J. W. Szostak </td> 559 <td>A genomewide search for ribozymes reveals an HDV-like sequence in the human CPEB3 gene.</td> 560 <td><a href="https://www.ribocentre.org/docs/HDV-like.html" target="_blank"><b>CPEB3 ribozyme</b></a></td> 561 <td>A HDV-like sequence in the human CPEB3 gene</td> 562 <td><a href="https://www.ncbi.nlm.nih.gov/pubmed/16990549" target="_blank"><b> Science 313 (5794): 1788-92.</b></a></td> 563 </tr> 564 <tr> 565 <td>2014</td> 566 <td>Skilandat, M., M. Rowinska-Zyrek and R. K. Sigel </td> 567 <td>Solution structure and metal ion binding sites of the human CPEB3 ribozyme's P4 domain.</td> 568 <td><a href="https://www.ribocentre.org/docs/HDV-like.html" target="_blank"><b>CPEB3 ribozyme</b></a></td> 569 <td>NMR solution structure of CPEB3 ribozyme's P4 domain</td> 570 <td><a href="https://www.ncbi.nlm.nih.gov/pubmed/24652468" target="_blank"><b> J Biol Inorg Chem 19 (6): 903-12.</b></a></td> 571 </tr> 572 <tr> 573 <td>2016</td> 574 <td>Skilandat, M., M. Rowinska-Zyrek and R. K. Sigel </td> 575 <td>Secondary structure confirmation and localization of Mg2+ ions in the mammalian CPEB3 ribozyme.</td> 576 <td><a href="https://www.ribocentre.org/docs/HDV-like.html" target="_blank"><b>CPEB3 ribozyme</b></a></td> 577 <td>NMR studies confirm secondary structure and Mg2+ location in CPEB3 ribozyme </td> 578 <td><a href="https://www.ncbi.nlm.nih.gov/pubmed/26966151" target="_blank"><b> RNA 22 (5): 750-63.</b></a></td> 579 </tr> 580 <tr> 581 <td>2021</td> 582 <td>Bendixsen, D. P., T. B. Pollock, G. Peri and E. J. Hayden </td> 583 <td>Experimental Resurrection of Ancestral Mammalian CPEB3 Ribozymes Reveals Deep Functional Conservation.</td> 584 <td><a href="https://www.ribocentre.org/docs/HDV-like.html" target="_blank"><b>CPEB3 ribozyme</b></a></td> 585 <td>The functional conservation of CPEB3 ribozyme in mammalian evolution</td> 586 <td><a href="https://www.ncbi.nlm.nih.gov/pubmed/33720319" target="_blank"><b> Mol Biol Evol 38 (7): 2843-2853.</b></a></td> 587 </tr> 588 <tr> 589 <td>2014</td> 590 <td>Meyer, M., H. Nielsen, V. Olieric, P. Roblin, S. D. Johansen, E. Westhof and B. Masquida </td> 591 <td>Speciation of a group I intron into a lariat capping ribozyme.</td> 592 <td><a href="https://www.ribocentre.org/docs/LC-ribozyme.html" target="_blank"><b>Lariat capping ribozyme</b></a></td> 593 <td>Crystal structures of the precleavage and postcleavage lariat-capping ribozymes</td> 594 <td><a href="https://www.ncbi.nlm.nih.gov/pubmed/24821772" target="_blank"><b>
594 Proc Natl Acad Sci U S A 111(21): 7659-7664.</b></a></td> 595 </tr> 596 <tr> 597 <td>2002</td> 598 <td>Johansen, S., C. Einvik and H. Nielsen </td> 599 <td>DiGIR1 and NaGIR1: naturally occurring group I-like ribozymes with unique core organization and evolved biological role.</td> 600 <td><a href="https://www.ribocentre.org/docs/LC-ribozyme.html" target="_blank"><b>Lariat capping ribozyme</b></a></td> 601 <td>REVIEW</td> 602 <td><a href="https://www.ncbi.nlm.nih.gov/pubmed/12458083" target="_blank"><b> Biochimie 84(9): 905-912.</b></a></td> 603 </tr> 604 <tr> 605 <td>2002</td> 606 <td>Vader, A., S. Johansen and H. Nielsen </td> 607 <td>The group I-like ribozyme DiGIR1 mediates alternative processing of pre-rRNA transcripts in Didymium iridis.</td> 608 <td><a href="https://www.ribocentre.org/docs/LC-ribozyme.html" target="_blank"><b>Lariat capping ribozyme</b></a></td> 609 <td>DiGIR1 mediates alternative processing of pre-rRNA transcripts in Didymium iridis</td> 610 <td><a href="https://www.ncbi.nlm.nih.gov/pubmed/12444968" target="_blank"><b> Eur J Biochem 269(23): 5804-5812.</b></a></td> 611 </tr> 612 <tr> 613 <td>2014</td> 614 <td>Tang, Y., H. Nielsen, B. Masquida, P. P. Gardner and S. D. Johansen </td> 615 <td>Molecular characterization of a new member of the lariat capping twin-ribozyme introns.</td> 616 <td><a href="https://www.ribocentre.org/docs/LC-ribozyme.html" target="_blank"><b>Lariat capping ribozyme</b></a></td> 617 <td>Molecular characterization of a new member of the lariat capping twin-ribozyme introns</td> 618 <td><a href="https://www.ncbi.nlm.nih.gov/pubmed/25342998" target="_blank"><b> Mob DNA 5: 25.</b></a></td> 619 </tr> 620 <tr> 621 <td>2021</td> 622 <td>Pietschmann, M., G. Tempel, M. Halladjian, N. Krogh and H. Nielsen </td> 623 <td>Use of a Lariat Capping Ribozyme to Study Cap Function In Vivo.</td> 624 <td><a href="https://www.ribocentre.org/docs/LC-ribozyme.html" target="_blank"><b>Lariat capping ribozyme</b></a></td> 625 <td>Use of a lariat capping ribozyme to study cap function in vivo</td> 626 <td><a href="https://www.ncbi.nlm.nih.gov/pubmed/32712925" target="_blank"><b> Methods Mol Biol 2167: 271-285.</b></a></td> 627 </tr> 628 <tr> 629 <td>1994</td> 630 <td>Johansen, S. and V. M. Vogt </td> 631 <td>An intron in the nuclear ribosomal DNA of Didymium iridis codes for a group I ribozyme and a novel ribozyme that cooperate in self-splicing.</td> 632 <td><a href="https://www.ribocentre.org/docs/LC-ribozyme.html" target="_blank"><b>Lariat capping ribozyme</b></a></td> 633 <td>Sequence discovered</td> 634 <td><a href="https://www.ncbi.nlm.nih.gov/pubmed/8124711" target="_blank"><b> Cell 76(4): 725-734.</b></a></td> 635 </tr> 636 <tr> 637 <td>1995</td> 638 <td>Decatur, W. A., C. Einvik, S. Johansen and V. M. Vogt </td> 639 <td>Two group I ribozymes with different functions in a nuclear rDNA intron.</td> 640 <td><a href="https://www.ribocentre.org/docs/LC-ribozyme.html" target="_blank"><b>Lariat capping ribozyme</b></a></td> 641 <td>Catalytic RNA element renamed as the group I-like ribozyme, GIR1</td> 642 <td><a href="https://www.ncbi.nlm.nih.gov/pubmed/7556099" target="_blank"><b> EMBO J 14(18): 4558-4568.</b></a></td> 643 </tr> 644 <tr> 645 <td>2005</td> 646 <td>Nielsen, H., E. Westhof and S. Johansen </td> 647 <td>An mRNA is capped by a 2', 5' lariat catalyzed by a group I-like ribozyme.</td> 648 <td><a href="https://www.ribocentre.org/docs/LC-ribozyme.html" target="_blank"><b>Lariat capping ribozyme</b></a></td> 649 <td>GIR1 makes tiny lariats</td> 650 <td><a href="https://www.ncbi.nlm.nih.gov/pubmed/16141078" target="_blank"><b> Science 309(5740): 1584-1587.</b></a></td> 651 </tr> 652 <tr> 653 <td>2008</td> 654 <td>eckert, B., H. Nielsen, C. Einvik, S. D. Johansen, E. Westhof and B. Masquida </td> 655 <td>Molecular modelling of the GIR1 branching ribozyme gives new insight into evolution of structurally related ribozymes.</td> 656 <td><a href="https://www.ribocentre.org/docs/LC-ribozyme.html" target="_blank"><b>Lariat capping ribozyme</b></a></td> 657 <td>Molecular modelling of the GIR1 branching ribozyme</td> 658 <td><a href="https://www.ncbi.nlm.nih.gov/pubmed/18219270" target="_blank"><b> EMBO J 27(4): 667-678.</b></a></td> 659 </tr> 660 <tr> 661 <td>2017</td> 662 <td>Krogh, N., M. Pietschmann, M. Schmid, T. H. Jensen and H. Nielsen </td> 663 <td>Lariat capping as a tool to manipulate the 5' end of individual yeast mRNA species in vivo.</td> 664 <td><a href="https://www.ribocentre.org/docs/LC-ribozyme.html" target="_blank"><b>Lariat capping ribozyme</b></a></td> 665 <td>Lariat capping as a tool to manipulate the 5' end of mRNA</td> 666 <td><a href="https://www.ncbi.nlm.nih.gov/pubmed/28159804" target="_blank"><b> RNA 23(5): 683-695.</b></a></td> 667 </tr> 668 <tr> 669 <td>2006</td> 670 <td>Klein, D. and A. Ferré-D'Amaré </td> 671 <td>Structural basis of glmS ribozyme activation by glucosamine-6-phosphate.</td> 672 <td><a href="https://www.ribocentre.org/docs/glms.html" target="_blank"><b>GlmS ribozyme</b></a></td> 673 <td>Crystal structure</td> 674 <td><a href="https://www.ncbi.nlm.nih.gov/pubmed/16990543" target="_blank"><b> Science (New York, N.Y.) 313(5794): 1752-1756.</b></a></td> 675 </tr> 676 <tr> 677 <td>2007</td> 678 <td>Cochrane, J., S. Lipchock and S. Strobel </td> 679 <td>Structural investigation of the GlmS ribozyme bound to Its catalytic cofactor.</td> 680 <td><a href="https://www.ribocentre.org/docs/glms.html" target="_blank"><b>GlmS ribozyme</b></a></td> 681 <td>Crystal structure</td> 682 <td><a href="https://www.ncbi.nlm.nih.gov/pubmed/17196404" target="_blank"><b> Chemistry & biology 14(1): 97-105.</b></a></td> 683 </tr> 684 <tr> 685 <td>2007</td> 686 <td>Klein, D., M. Been and A. Ferré-D'Amaré </td> 687 <td>Essential role of an active-site guanine in glmS ribozyme catalysis.</td> 688 <td><a href="https://www.ribocentre.org/docs/glms.html" target="_blank"><b>GlmS ribozyme</b></a></td> 689 <td>Essential role of an active-site guanine G40 in glmS ribozyme catalysis</td> 690 <td><a href="https://www.ncbi.nlm.nih.gov/pubmed/17990888" target="_blank"><b> Journal of the American Chemical Society 129(48): 14858-14859.</b></a></td> 691 </tr> 692 <tr> 693 <td>2017</td> 694 <td>Schüller, A., D. Matzner, C. Lünse, V. Wittmann, C. Schumacher, S. Unsleber, H. Brötz-Oesterhelt, C. Mayer, G. Bierbaum and G. Mayer </td> 695 <td>Activation of the glmS Ribozyme Confers Bacterial Growth Inhibition.</td> 696 <td><a href="https://www.ribocentre.org/docs/glms.html" target="_blank"><b>GlmS ribozyme</b></a></td> 697 <td>GlcN6P cofactor play a variety of catalytic roles in glmS ribozyme</td> 698 <td><a href="https://www.ncbi.nlm.nih.gov/pubmed/28012261" target="_blank"><b> Chembiochem : a European journal of chemical biology 18(5): 435-440.</b></a></td> 699 </tr> 700 <tr> 701 <td>
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782Bingaman, J., S. Zhang, D. Stevens, N. Yennawar, S. Hammes-Schiffer and P. Bevilacqua </td> 783 <td>The GlcN6P cofactor plays multiple catalytic roles in the glmS ribozyme.</td> 784 <td><a href="https://www.ribocentre.org/docs/glms.html" target="_blank"><b>GlmS ribozyme</b></a></td> 785 <td>GlcN6P cofactor play a variety of catalytic roles in glmS ribozyme</td> 786 <td><a href="https://www.ncbi.nlm.nih.gov/pubmed/28192411" target="_blank"><b> Nature chemical biology 13(4): 439-445.</b></a></td> 787 </tr> 788 <tr> 789 <td>2018</td> 790 <td>Cruz-Bustos, T., S. Ramakrishnan, C. Cordeiro, M. Ahmed and R. 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1903A manganese-dependent ribozyme in the 3'-untranslated region of Xenopus Vg1 mRNA.</td> 1904 <td><a href="https://www.ribocentre.org/docs/Vg1.html" target="_blank"><b>Vg1 ribozyme</b></a></td> 1905 <td>Discovery that manganese-dependent ribozyme occurs naturally in the 3'-UTR of Vg1 and beta-actin mRNAs</td> 1906 <td><a href="https://www.ncbi.nlm.nih.gov/pubmed/18753150" target="_blank"><b> Nucleic Acids Res 36(17): 5530-5539.</b></a></td> 1907 </tr> 1908 <tr> 1909 <td>1990</td> 1910 <td>Saville, B. J. and R. A. Collins </td> 1911 <td>A site-specific self-cleavage reaction performed by a novel RNA in neurospora mitochondria.</td> 1912 <td><a href="https://www.ribocentre.org/docs/VS-ribozyme.html" target="_blank"><b>VS ribozyme</b></a></td> 1913 <td>discovery</td> 1914 <td><a href="https://www.ncbi.nlm.nih.gov/pubmed/2160856" target="_blank"><b> Cell 61(4): 685-696.</b></a></td> 1915 </tr> 1916 <tr> 1917 <td>1995</td> 1918 <td>Beattie, T. L., J. E. Olive and R. A. Collins </td> 1919 <td>A secondary-structure model for the self-cleaving region of Neurospora VS RNA.</td> 1920 <td><a href="https://www.ribocentre.org/docs/VS-ribozyme.html" target="_blank"><b>VS ribozyme</b></a></td> 1921 <td>secondary structure</td> 1922 <td><a href="https://www.ncbi.nlm.nih.gov/pubmed/7753865" target="_blank"><b> Proc Natl Acad Sci U S A 92(10): 4686-4690.</b></a></td> 1923 </tr> 1924 <tr> 1925 <td>2001</td> 1926 <td>D.A. Lafontaine, D.G. Norman and D.M.J. Lilley </td> 1927 <td>Structure, folding and activity of the VS ribozyme : Importance of the 2-3-6 helical junction </td> 1928 <td><a href="https://www.ribocentre.org/docs/VS-ribozyme.html" target="_blank"><b>VS ribozyme</b></a></td> 1929 <td>Importance of the 2-3-6 helical junction</td> 1930 <td><a href="https://www.ncbi.nlm.nih.gov/pubmed/11250907" target="_blank"><b>EMBO J. 20 1415-1424 </b></a></td> 1931 </tr> 1932 <tr> 1933 <td>2001</td> 1934 <td>Lafontaine, D. A., T. J. Wilson, D. G. Norman and D. M. Lilley </td> 1935 <td>The A730 loop is an important component of the active site of the VS ribozyme.</td> 1936 <td><a href="https://www.ribocentre.org/docs/VS-ribozyme.html" target="_blank"><b>VS ribozyme</b></a></td> 1937 <td>A730 loop is important</td> 1938 <td><a href="https://www.ncbi.nlm.nih.gov/pubmed/11575922" target="_blank"><b> J Mol Biol 312(4): 663-674.</b></a></td> 1939 </tr> 1940 <tr> 1941 <td>2001</td> 1942 <td>Flinders, J. and T. Dieckmann </td> 1943 <td>A pH controlled conformational switch in the cleavage site of the VS ribozyme substrate RNA.</td> 1944 <td><a href="https://www.ribocentre.org/docs/VS-ribozyme.html" target="_blank"><b>VS ribozyme</b></a></td> 1945 <td>NMR structure of the isolated substrate helix</td> 1946 <td><a href="https://www.ncbi.nlm.nih.gov/pubmed/11350168" target="_blank"><b> J Mol Biol 308(4): 665-679.</b></a></td> 1947 </tr> 1948 <tr> 1949 <td>2002</td> 1950 <td>D.A. Lafontaine, D.G. Norman and D. M.J. Lilley </td> 1951 <td>The global structure of the VS ribozyme. </td> 1952 <td><a href="https://www.ribocentre.org/docs/VS-ribozyme.html" target="_blank"><b>VS ribozyme</b></a></td> 1953 <td>The global structure of the VS ribozyme</td> 1954 <td><a href="https://www.ncbi.nlm.nih.gov/pubmed/12006498" target="_blank"><b>EMBO J. 21, 2461-2471 </b></a></td> 1955 </tr> 1956 <tr> 1957 <td>2002</td> 1958 <td>Lafontaine, D. A., T. J. Wilson, Z.-Y. Zhao and D. M. J. Lilley </td> 1959 <td>Functional Group Requirements in the Probable Active Site of the VS Ribozyme.</td> 1960 <td><a href="https://www.ribocentre.org/docs/VS-ribozyme.html" target="_blank"><b>VS ribozyme</b></a></td> 1961 <td>A756 is critical for catalysis</td> 1962 <td><a href="https://www.ncbi.nlm.nih.gov/pubmed/12368096" target="_blank"><b> Journal of Molecular Biology 323(1): 23-34.</b></a></td> 1963 </tr> 1964 <tr> 1965 <td>2005</td> 1966 <td>Campbell, D. O. and P. Legault </td> 1967 <td>Nuclear magnetic resonance structure of the Varkud satellite ribozyme stem-loop V RNA and magnesium-ion binding from chemical-shift mapping.</td> 1968 <td><a href="https://www.ribocentre.org/docs/VS-ribozyme.html" target="_blank"><b>VS ribozyme</b></a></td> 1969 <td>NMR structure of SL5</td> 1970 <td><a href="https://www.ncbi.nlm.nih.gov/pubmed/15766243" target="_blank"><b>
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Hansen, N. Ban, P. B. Moore and T. A. Steitz </td> 2511 <td>The structural basis of ribosome activity in peptide bond synthesis.</td> 2512 <td><a href="https://www.ribocentre.org/docs/Ribosome.html" target="_blank"><b>Ribosome</b></a></td> 2513 <td>The ribosome is a ribozyme </td> 2514 <td><a href="https://www.ncbi.nlm.nih.gov/pubmed/10937990" target="_blank"><b> Science 289 (5481): 920-30.</b></a></td> 2515 </tr> 2516 <tr> 2517 <td>2000</td> 2518 <td>Cech, T. R. </td> 2519 <td>Structural biology. The ribosome is a ribozyme.</td> 2520 <td><a href="https://www.ribocentre.org/docs/Ribosome.html" target="_blank"><b>Ribosome</b></a></td> 2521 <td>The ribosome is a ribozyme </td> 2522 <td><a href="https://www.ncbi.nlm.nih.gov/pubmed/10960319" target="_blank"><b> Science 289(5481): 878-9.</b></a></td> 2523 </tr> 2524 <tr> 2525 <td>2000</td> 2526 <td>Muth, G. W., L. Ortoleva-Donnelly and S. A. 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Hashem </td> 2687 <td>Cryo-EM structure of the RNA-rich plant mitochondrial ribosome.</td> 2688 <td><a href="https://www.ribocentre.org/docs/Ribosome.html" target="_blank"><b>Ribosome</b></a></td> 2689 <td>Cryo-EM structure of the RNA-rich plant mitochondrial ribosome</td> 2690 <td><a href="https://www.ncbi.nlm.nih.gov/pubmed/32251374" target="_blank"><b> Nat Plants 6 (4): 377-383.</b></a></td> 2691 </tr> 2692 <tr> 2693 <td>2020</td> 2694 <td>Loveland, A. B., G. Demo and A. A. Korostelev </td> 2695 <td>Cryo-EM of elongating ribosome with EF-Tuâ¢GTP elucidates tRNA proofreading.</td> 2696 <td><a href="https://www.ribocentre.org/docs/Ribosome.html" target="_blank"><b>Ribosome</b></a></td> 2697 <td>Cryo-EM of elongating ribosome with EF-Tuâ¢GTP elucidates tRNA proofreading</td> 2698 <td><a href="https://www.ncbi.nlm.nih.gov/pubmed/32612237" target="_blank"><b> Nature 584 (7822): 640-645.</b></a></td> 2699 </tr> 2700 <tr> 2701 <td>2020</td> 2702 <td>Aibara, S., V. Singh, A. 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Ban </td> 2719 <td>Structural basis of translation termination, rescue, and recycling in mammalian mitochondria.</td> 2720 <td><a href="https://www.ribocentre.org/docs/Ribosome.html" target="_blank"><b>Ribosome</b></a></td> 2721 <td>Structural basis of translation termination, rescue, and recycling in mammalian mitochondria</td> 2722 <td><a href="https://www.ncbi.nlm.nih.gov/pubmed/33878294" target="_blank"><b> Mol Cell 81 (12): 2566-2582.e6.</b></a></td> 2723 </tr> 2724 <tr> 2725 <td>2022</td> 2726 <td>Itoh, Y., A. Khawaja, I. Laptev, M. Cipullo, I. Atanassov, P. Sergiev, J. Rorbach and A. Amunts </td> 2727 <td>Mechanism of mitoribosomal small subunit biogenesis and preinitiation.</td> 2728 <td><a href="https://www.ribocentre.org/docs/Ribosome.html" target="_blank"><b>Ribosome</b></a></td> 2729 <td>Mechanism of mitoribosomal small subunit biogenesis and preinitiation</td> 2730 <td><a href="https://www.ncbi.nlm.nih.gov/pubmed/35676484" target="_blank"><b> Nature 606 (7914): 603-608.</b></a></td> 2731 </tr> 2732 </table><br /><br /> 2733</div></body></html> 2734 2735</div> 2736 2737 </div> 2738 </div> 2739 2740 <div id="footer" class="panel"> 2741 <div class="panel-footer" style='background-color: #333333; color: #eeeeee;'> 2742 <div class="container-fluid"> 2743 <div class="row"> 2744 <div class="col-sm-4"> 2745 2746 <p>© 2024 GZNL-RDC. </p> 2747 <p>We are part of the <a href="https://gzlab.ac.cn">Guangzhou Laboratory</a> and <a href="http://www.rnacentre.org/">RNAcentre</a> and <a href="http://www.gzsys.org.cn/">Sun Yat-sen University</a>.</p> 2748 <p>Site made with <a href="https://jekyllrb.com">Jekyll</a>; <a href="/aboutwebsite.html">copy and modify it for your own research group</a>.</p> 2749 <p> </p> 2750 <p> </p> 2751 </div> 2752 2753 <div class="col-sm-4"> 2754 Funding:<br /> 2755 - <a href="https://gzlab.ac.cn">R&D Programs of Guangzhou Laboratory</a><br /> 2756 - <a href="http://www.most.gov.cn/">MOST IT+BT projects</a> <br /> 2757 - <a href="https://www.nsfc.gov.cn/">NSFC</a> <br /> 2758 <br> 2759
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