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568	
569	<h1 id="homePageTitle">Vestnik dermatologii i venerologii</h1>
570			<div id="additionalHomeContent"><div style="float: right;">
571<p><a title="SCImago Journal &amp; Country Rank" href="https://www.scimagojr.com/journalsearch.php?q=24973&amp;tip=sid&amp;exact=no"><img src="https://www.scimagojr.com/journal_img.php?id=24973" alt="SCImago Journal &amp; Country Rank" border="0"></a><br><a title="SciteSore by SCOPUS" href="https://www.scopus.com/sourceid/24973"><img style="float: right;" src="https://vestnikdv.ru/files/journals/1/images/CiteScore/CiteScore2025_Vestnik_Dermatologii.png" alt="SciteSore by SCOPUS" border="0"></a></p>
572</div>
573<p>Peer-review academic medical journal on dermatology, venereology and cosmetology.&nbsp;</p>
574<h4>About</h4>
575<p>The journal founded in 1924 is the oldest journal worldwide in the field of dermatology and venereology.</p>
576<p>This is an open-access, peer-review international journal that publishes original papers in efficacy and safety of medicines, the analysis of clinical practice, and its compliance with national and international recommendations.&nbsp;<u></u><u></u></p>
577<p>The journal cater for a wide range of readers comprising clinical and medical practitioners of general and advanced medical and clinical research, academicians, researchers, and students, as well as for the international business circle of people in the field that are establishing new skin-care products.<u></u><u></u></p>
578<p>The journal is specially interested in research related to clinical trials, procedural dermatology, patient-centered care and immunodermatology. Papers on research methodology, health care quality, and improving the delivery of patient care, including systematic reviews and evidence-based guidelines, are also welcomed.<u></u><u></u></p>
579<h4>Editor-in-Chief</h4>
580<ul>
581<li>Prof. Aleksey A. Kubanov, MD, Dr.Sci. (Med.)<br>ORCID iD:&nbsp;<a href="http://orcid.org/0000-0002-7625-0503" target="_blank" rel="noopener">0000-0002-7625-0503</a></li>
582</ul>
583<h4>Founder &amp; Publisher</h4>
584<ul>
585<li><a href="https://mail.yandex.ru/re.jsx?h=a,6VAMGYlkOhUteX8kwXSWag&amp;l=aHR0cHM6Ly9jbmlrdmkucnUv">State Research Center of Dermatovenereology and Cosmetology, Ministry of Healthcare of the Russian Federation</a></li>
586<li><a href="https://mail.yandex.ru/re.jsx?h=a,vy2YW2dvK9s9gHvfagICFA&amp;l=aHR0cDovL3d3dy5yb2R2LnJ1Lw">Russian Society for Dermatologists and Cosmetologists</a></li>
587</ul>
588<h4>Articles types</h4>
589<ul>
590<li>reviews</li>
591<li>systematic reviews and metaanalyses</li>
592<li>original research</li>
593<li>clinical case reports and series</li>
594<li>letters to the editor</li>
595<li>short communications</li>
596<li>clinial practice guidelines</li>
597</ul>
598<hr>
599<h4>APC, Publication &amp; Distribution</h4>
600<ul>
601<li>Bimonthly issues (6 times a year)</li>
602<li>Continuoulsly publications online (Online First)</li>
603<li>Platinum Open Access (no APC)</li>
604<li>
604Creative Commons Attribution 4.0 International <a href="https://creativecommons.org/licenses/by/4.0/">(CC BY 4.0)</a> License</li>
605<li>articles in English &amp; Russian</li>
606</ul>
607<h4>Indexation</h4>
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611<li><a href="https://www.elibrary.ru/title_about_new.asp?id=7685" target="_blank" rel="noopener">Russian Science Citation Index (on WoS)</a></li>
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614<li>Ulrich’s International Periodicals Directory</li>
615<li>Dimensions</li>
616<li>VAK</li>
617<li>EGPNI (White List)</li>
618<li><a href="https://scholar.oversea.cnki.net/journal/index/SJPD004246092841" target="_blank" rel="noopener">CNKI</a></li>
619<li><a href="https://explore.openalex.org/sources/S2751822536" target="_blank" rel="noopener">OpenAlexPage</a></li>
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650				<p class="authors">Yakovleva A., Nikonorova E., Kondrakhina I., Nikonorov A., Kubanov A.</p>			</div>
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675			<h3>Vol 102, No 3 (2026)</h3>
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679				<div class="titleAuthors">
680			<ul>
681				<li><b>Year:</b> 2026</li>
682									<li><b>Published:</b> 27.08.2026</li>
683								<li><b>Articles:</b> 9</li>
684				<li><b>URL:</b> <a href="https://vestnikdv.ru/jour/issue/view/123">https://vestnikdv.ru/jour/issue/view/123</a></li>
685                                                                                                        <li><b>DOI:</b> <a id="pub-id::doi" href="https://doi.org/10.25208/vdv.1023">https://doi.org/10.25208/vdv.1023</a></li>
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705		<h5 class="articleTitle">
706			<a href="https://vestnikdv.ru/jour/article/view/16959">Clinical presentation of onychodystrophies depending on their severity: overview of specific cases</a>
707		</h5>
708		<div class="issueArticleInformation">
709			<div class="articleCover">
710							</div>
711                        				<div class="authors">
712					Saranyuk R.V., Gosteva T.A.
713				</div>
714                        						<div class="abstract">
715				<h6>Abstract</h6>
716				<div class="articleAbstract" id="articleAbstract00">
717					<div><p>Nail dystrophies (onychodystrophies) are non-infectious processes characterized by changes in the structure, surface, color, and consistency of the nail. The wide variety of onychodystrophies is determined by their etiopathogenesis and the anatomical and physiological characteristics of the nail system. Onychodystrophies can occur both as an underlying disease and as clinical manifestations of certain skin and systemic disorders. Striking clinical examples include hypertrophic osteoarthropathy (Hippocratic nails) associated with severe systemic pathology or abnormal nail changes associated with lichen planus, which begin with the appearance of longitudinal grooves and onychorrhexis and subsequently have variable outcomes and prognoses. Many types of onychodystrophies are often nonspecific and cannot serve as pathognomonic signs of a specific disease, which, in turn, negatively impacts differential diagnostic testing and timely diagnosis. Of note is that the time a patient seeks dermatological attention does not always coincide with the onset of onychodystrophies, which directly impacts the assessment of the nail lesion severity. Like any pathological condition, onychodystrophies tend to change over time, which may be due to the duration of the pathological process and/or the action of a trigger factor, its nature, and possible associated conditions. Understanding the development of pathological nail changes can be crucial for clinical assessment and diagnosis of existing changes, selection of patient management strategies, and determining the prognosis and outcome of the disease.</p>
718<p>This overview examines the clinical presentation of certain types of onychodystrophies depen
718ding on their severity, with the transition from one type to another, and discusses possible causes and aspects of the etiopathogenesis of these changes. The authors also attempted to systematize the severity of certain types of onychodystrophies to simplify the clinical assessment of abnormal nail changes and adequately evaluate the outcome of the disease.</p></div>
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738						<div class="pages"><b>Vestnik dermatologii i venerologii</b>. 2026;102(3):13-22</div>
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745					13-22
746				</span>
747						<img src="/img/style/views.png" alt="views">
748			<span id="articleViews_16959">
749				<img style='margin: auto;' src='/img/style/loadingSmall.gif'></td></tr></table>
750				
750<script>$("#articleViews_16959").load('https://vestnikdv.ru/jour/article/articleViews/16959');</script>
750
751			</span>
752		</div>
753	</div>
754	<div class="dark issueArticlesFiles">
755										                					                					                									<div class="issueArticlesFilesBlock">
756                                                                                                        <a href="https://vestnikdv.ru/jour/article/view/16959/2177" class="file">
757                                                							<img src="/img/labels/pdf.png" alt="PDF"><br><span class="issueArticlesLabel">(Rus)</span>
758													</a>
759					</div>
760					                                		<a href="https://vestnikdv.ru/jour/article/xml/16959" class="file" target="_blank"><img src="/img/labels/xml.png" alt="JATS&nbsp;XML">
761			<br><span class="issueArticlesLabel">(JATS&nbsp;XML)</span>
762		</a>
763	</div>
764	<div class="heading"><h4>ORIGINAL STUDIES</h4></div>
765		
766					<div class="dark issueArticlesData">
767		<h5 class="articleTitle">
768			<a href="https://vestnikdv.ru/jour/article/view/16997">Efficacy of therapy for androgenetic alopecia in women using hydrodermabrasion and needle-free infusion: a prospective study</a>
769		</h5>
770		<div class="issueArticleInformation">
771			<div class="articleCover">
772							</div>
773                        				<div class="authors">
774					Gallyamova Y.A., Rusina T.S., Dudina E.S.
775				</div>
776                        						<div class="abstract">
777				<h6>Abstract</h6>
778				<div class="articleAbstract" id="articleAbstract10">
779					<div><p><strong>BACKGROUND:</strong><strong> </strong>Androgenetic alopecia is a widespread disorder that presents therapeutic challenges due to patients' inflated expectations, low treatment adherence associated with inconvenient topical application, and concerns regarding adverse effects. Therefore, exploring new non-invasive approaches to managing hair loss and stimulating hair growth has become particularly relevant.</p>
780<p><strong>AIM:</strong><strong> </strong>To<strong> </strong>evaluate the efficacy and tolerability of the needle-free JetPeel hydro-dermabrasion technology combined with a serum containing DHQG (dihydroquercetin-glucoside), glycine, zinc chloride, EGCG (epigallocatechin-gallate-glucoside), acetyl tetrapeptide-3, and biochanin A (from red clover extract) in women with androgenetic alopecia in a real-world clinical setting.</p>
781<p><strong>METHODS:</strong><strong> </strong>A<strong> </strong>prospective, uncontrolled, pragmatic study was conducted, blinded to the trichogram assessor. It enrolled 22 women with Ludwig stage I–III androgenetic alopecia. The patients received JetPeel procedures with serum once weekly for 5 weeks, along with daily home application of the serum. The analyzed trichoscopic parameters included the proportion of terminal/vellus hairs, single/double/triple follicular units, hair diameter. Subjective satisfaction and comfort were assessed using a 5-point Likert scale and a Visual Analogue Scale, respectively.</p>
782<p><strong>RESULTS:</strong> After 5 weeks, a statistically significant reduction in the proportion of single follicular units by 20% (<em>p</em> = 0.001) and an increase in the proportion of double units by 11.8% (<em>p</em> = 0.003) were observed. Median satisfaction was 4.5 points (86.4% of patients rated the outcome as 4 or 5). Comfort according to Visual Analogue Scale was 8.9 ± 1.2 out of 10. No serious adverse events were reported.</p>
783<p><strong>CONCLUSION:</strong> The JetPeel technology with complex serum demonstrates early positive trichoscopic changes, high subjective satisfaction, and a favorable safety profile, supporting its recommendation as an additional treatment option for androgenetic alopecia in women.</p></div>
784				</div>
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787				
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803						<div class="pages"><b>Vestnik dermatologii i venerologii</b>. 2026;102(3):23-32</div>
804		</div>
805	</div>
806	<div class="dark issueArticlesViews">
807		<div>
808								<img src="/img/style/pages.png" alt="pages">
809				<span>
810					23-32
811				</span>
812						<img src="/img/style/views.png" alt="views">
813			<span id="articleViews_16997">
814				<img style='margin: auto;' src='/img/style/loadingSmall.gif'></td></tr></table>
815				
815<script>$("#articleViews_16997").load('https://vestnikdv.ru/jour/article/articleViews/16997');</script>
815
816			</span>
817		</div>
818	</div>
819	<div class="dark issueArticlesFiles">
820										                					                					                									<div class="issueArticlesFilesBlock">
821                                                                                                        <a href="https://vestnikdv.ru/jour/article/view/16997/2178" class="file">
822                                                							<img src="/img/labels/pdf.png" alt="PDF"><br><span class="issueArticlesLabel">(Rus)</span>
823													</a>
824					</div>
825					                                		<a href="https://vestnikdv.ru/jour/article/xml/16997" class="file" target="_blank"><img src="/img/labels/xml.png" alt="JATS&nbsp;XML">
826			<br><span class="issueArticlesLabel">(JATS&nbsp;XML)</span>
827		</a>
828	</div>
829		
830					<div class="light issueArticlesData">
831		<h5 class="articleTitle">
832			<a href="https://vestnikdv.ru/jour/article/view/17005">Clinical predictors of biologic therapy efficacy in moderate-to-severe psoriasis</a>
833		</h5>
834		<div class="issueArticleInformation">
835			<div class="articleCover">
836							</div>
837                        				<div class="authors">
838					Karamova A.E., Vorontsova A.A., Nikonorov A.A., Nikonorova E.R., Kubanov A.A.
839				</div>
840                        						<div class="abstract">
841				<h6>Abstract</h6>
842				<div class="articleAbstract" id="articleAbstract11">
843					<div><p><strong>BACKGROUND:</strong> Despite the accumulated data on the significance of clinical indicators for predicting the efficacy of interleukin inhibitor therapy, the findings are contradictory.</p>
844<p><strong>AIM:</strong><strong> </strong>To<strong> </strong>determine the significance of clinical signs as predictors of the efficacy or failure of biologic therapy of moderate-to-severe psoriasis.</p>
845<p><strong>METHODS:</strong> The study enrolled 156 patients with psoriasis vulgaris (L40.0 according to ICD-10). The severity of the disease was assessed using standard clinical indices — PASI and BSA. The clinical efficacy was determined by the percentage of PASI reduction 50/75/90/100: good response (PASI ≥ 75) and low efficacy/poor response (PASI ≤ 50). The findings were statistically analyzed and visualized using RStudio and the R programming language. To identify factors associated with treatment efficacy, three analytical approaches were used: multivariate logistic regression, random forest algorithm, and regularized logistic regression (LASSO).</p>
846<p><strong>RESULTS:</strong><strong> </strong>By<strong> </strong>Week 16, PASI scores ≥ 75 were achieved in 113 patients (72%), insufficient efficacy (PASI ≤ 50) was observed in 43 patients (27%); by Week 26 — in 129 (84%) and 24 (16%), respectively. The highest proportion of patients with insufficient responses was observed in the adalimumab and etanercept groups at Weeks 16 and 26 (46% and 57%; 27% and 25%, respectively). It has been established that the key and most consistent predictor of the efficacy of biologic therapy in patients with moderate-to-severe psoriasis is body mass index: an increase in this indicator is associated with a reduced likelihood of achieving a good clinical response. Arterial hypertension is also associated with lower treatment efficacy, while a higher HDL level can be considered an additional favorable prognostic factor.</p>
847<p><strong>CONCLUSION:</strong> Consideration of the metabolic and cardiovascular patient characteristics may increase the validity of the choice of biologic therapy in clinical practice.</p></div>
848				</div>
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865
866			</div>
867						<div class="pages"><b>Vestnik dermatologii i venerologii</b>. 2026;102(3):33-42</div>
868		</div>
869	</div>
870	<div class="light issueArticlesViews">
871		<div>
872								<img src="/img/style/pages.png" alt="pages">
873				<span>
874					33-42
875				</span>
876						<img src="/img/style/views.png" alt="views">
877			<span id="articleViews_17005">
878				<img style='margin: auto;' src='/img/style/loadingSmall.gif'></td></tr></table>
879				
879<script>$("#articleViews_17005").load('https://vestnikdv.ru/jour/article/articleViews/17005');</script>
879
880			</span>
881		</div>
882	</div>
883	<div class="light issueArticlesFiles">
884										                					                					                									<div class="issueArticlesFilesBlock">
885                                                                                                        <a href="https://vestnikdv.ru/jour/article/view/17005/2179" class="file">
886                                                							<img src="/img/labels/pdf.png" alt="PDF"><br><span class="issueArticlesLabel">(Rus)</span>
887													</a>
888					</div>
889					                                		<a href="https://vestnikdv.ru/jour/article/xml/17005" class="file" target="_blank"><img src="/img/labels/xml.png" alt="JATS&nbsp;XML">
890			<br><span class="issueArticlesLabel">(JATS&nbsp;XML)</span>
891		</a>
892	</div>
893		
894					<div class="dark issueArticlesData">
895		<h5 class="articleTitle">
896			<a href="https://vestnikdv.ru/jour/article/view/16989">Results of the national consensus on the unification of dermatoscopic terminology in the Russian language</a>
897		</h5>
898		<div class="issueArticleInformation">
899			<div class="articleCover">
900							</div>
901                        				<div class="authors">
902					Martynov A.A., Sokolova A.V., Kubanov A.A., Vlasova A.V., Rakhmatulina M.R., Sysoeva T.A., Te V.L.
903				</div>
904                        						<div class="abstract">
905				<h6>Abstract</h6>
906				<div class="articleAbstract" id="articleAbstract12">
907					<div><p><strong>BACKGROUND</strong><strong>:</strong> The absence of a unified dermatoscopic terminology in the Russian language limits the descriptive capabilities of dermatoscopic findings, which complicates interdisciplinary interaction and reduces the possibilities for dynamic monitoring of patients with skin and adnexal lesions, primarily neoplasms. In 2016, the International Dermoscopy Society proposed a standardized terminology. Its implementation into everyday clinical practice in the Russian Federation required adaptation and expert validation taking into account linguistic features.</p>
908<p><strong>AIM</strong><strong>: </strong>To develop and validate a Russian-language version of the universally accepted dermatoscopic terminology by conducting an expert consensus.</p>
909<p><strong>METHODS: </strong>The study was conducted in the format of a single-stage expert consensus with elements of quantitative agreement assessment (Delphi method). The experts were dermatovenereologists and oncologists with experience in using dermoscopy in clinical practice.</p>
910<p>A standardized questionnaire based on English terms adopted at the 3rd Consensus Conference of the International Dermoscopy Society (2016) was used for the study. It also included corresponding Russian adapted terms, schematic images of dermatoscopic structures, definitions, histopathological correlations and clinical significance, as well as the "agree", "disagree", and "comments" fields.</p>
911<p><strong>RESULTS:</strong> The study was conducted from December 15, 2025, to February 15, 2026. A total of 67 specialists participated in the expert consensus, including 48 dermatovenerologists (71.6%), 16 oncologists (23.9%), and 3 physicians who reported having both specialties (4.5%). Consensus was defined as agreement of ≥ 70% of experts. A high level of agreement was observed among both oncologists (agreement coefficient 0.84) and dermatovenerologists (0.82). Specialists reporting both specialties demonstrated the highest activity in proposing alternative options (proposal coefficient 0.13). Regarding vascular structures, consensus was reached on all proposed terms with minimal need for adjustments. Alternative terms and comments proposed by experts were subjected to quantitative and qualitative analysis, identifying linguistic and clinical remarks.</p>
912<p><strong>CONCLUSION: </strong>A<strong> </strong>terminology in the Russian language has been developed and validated, ensuring unification of the dermatoscopic vocabulary in the Russian Federation. The multidisciplinary approach using the Delphi method enabled achieving high expert consensus on dermatoscopic terms. The obtained results provide a methodological basis for standardizing dermatoscopic diagnosis, developing unified protocols for dermatoscopic examination, and implementing educational programs on dermatoscopy.</p></div>
913				</div>
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930
931			</div>
932						<div class="pages"><b>Vestnik dermatologii i venerologii</b>. 2026;102(3):43-52</div>
933		</div>
934	</div>
935	<div class="dark issueArticlesViews">
936		<div>
937								<img src="/img/style/pages.png" alt="pages">
938				<span>
939					43-52
940				</span>
941						<img src="/img/style/views.png" alt="views">
942			<span id="articleViews_16989">
943				<img style='margin: auto;' src='/img/style/loadingSmall.gif'></td></tr></table>
944				
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944
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946		</div>
947	</div>
948	<div class="dark issueArticlesFiles">
949										                					                					                									<div class="issueArticlesFilesBlock">
950                                                                                                        <a href="https://vestnikdv.ru/jour/article/view/16989/2180" class="file">
951                                                							<img src="/img/labels/pdf.png" alt="PDF"><br><span class="issueArticlesLabel">(Rus)</span>
952													</a>
953					</div>
954					                                		<a href="https://vestnikdv.ru/jour/article/xml/16989" class="file" target="_blank"><img src="/img/labels/xml.png" alt="JATS&nbsp;XML">
955			<br><span class="issueArticlesLabel">(JATS&nbsp;XML)</span>
956		</a>
957	</div>
958	<div class="heading"><h4>GUIDELINES FOR PRACTITIONERS</h4></div>
959		
960					<div class="dark issueArticlesData">
961		<h5 class="articleTitle">
962			<a href="https://vestnikdv.ru/jour/article/view/16975">Pyoderma gangrenosum: the challenge of differential diagnosis in a patient with atypical localization</a>
963		</h5>
964		<div class="issueArticleInformation">
965			<div class="articleCover">
966							</div>
967                        				<div class="authors">
968					Olisova O.Y., Grabovskaya O.V., Bobkova A.E., Glushak V.V.
969				</div>
970                        						<div class="abstract">
971				<h6>Abstract</h6>
972				<div class="articleAbstract" id="articleAbstract20">
973					<div><p>Pyoderma gangrenosum is a rare, immune-mediated skin disease that belongs to neutrophilic dermatoses. It typically affects the lower extremities, making isolated involvement of the axillary regions a significant diagnostic challenge.</p>
974<p>We present a clinical case of a 34-year-old patient with a nine-month history of the disease, manifested by painful ulcerative-erosive eruptions in the axillary areas. At the pre-hospital stage, pyoderma, allergic contact dermatitis, dermatophytosis, and pemphigus vegetans were incorrectly diagnosed, which is confirmed by the lack of therapeutic effect from antibacterial and antimycotic therapy. The diagnosis of pyoderma gangrenosum was verified based on the characteristic clinical presentation (multiple deep ulcerative defects with undermined edges of a bright red-pink color with a bluish tinge, the bases of the ulcers are covered with a purulent-necrotic scab) and histological examination results. Systemic glucocorticosteroid therapy (prednisolone 85 mg/day) was effective and led to regression of the lesions; however, disease recurrence occurred when the dose was reduced to 35 mg/day.</p>
975<p>This case underscores the critical importance of early differential diagnosis of pyoderma gangrenosum in intertriginous zones to prevent iatrogenic complications and the pathergy phenomenon.</p></div>
976				</div>
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994			</div>
995						<div class="pages"><b>Vestnik dermatologii i venerologii</b>. 2026;102(3):53-60</div>
996		</div>
997	</div>
998	<div class="dark issueArticlesViews">
999		<div>
1000								<img src="/img/style/pages.png" alt="pages">
1001				<span>
1002					53-60
1003				</span>
1004						<img src="/img/style/views.png" alt="views">
1005			<span id="articleViews_16975">
1006				<img style='margin: auto;' src='/img/style/loadingSmall.gif'></td></tr></table>
1007				
1007<script>$("#articleViews_16975").load('https://vestnikdv.ru/jour/article/articleViews/16975');</script>
1007
1008			</span>
1009		</div>
1010	</div>
1011	<div class="dark issueArticlesFiles">
1012										                					                					                									<div class="issueArticlesFilesBlock">
1013                                                                                                        <a href="https://vestnikdv.ru/jour/article/view/16975/2181" class="file">
1014                                                							<img src="/img/labels/pdf.png" alt="PDF"><br><span class="issueArticlesLabel">(Rus)</span>
1015													</a>
1016					</div>
1017					                                		<a href="https://vestnikdv.ru/jour/article/xml/16975" class="file" target="_blank"><img src="/img/labels/xml.png" alt="JATS&nbsp;XML">
1018			<br><span class="issueArticlesLabel">(JATS&nbsp;XML)</span>
1019		</a>
1020	</div>
1021		
1022					<div class="light issueArticlesData">
1023		<h5 class="articleTitle">
1024			<a href="https://vestnikdv.ru/jour/article/view/16995">Cutaneous protothecosis associated with long-term topical corticosteroid use: clinicopathological diagnostic pointers</a>
1025		</h5>
1026		<div class="issueArticleInformation">
1027			<div class="articleCover">
1028							</div>
1029                        				<div class="authors">
1030					Burtseva N.Y., Makhinenko I.O., Melnikova T.V., Monakhov K.N., Sokolovskiy E.V.
1031				</div>
1032                        						<div class="abstract">
1033				<h6>Abstract</h6>
1034				<div class="articleAbstract" id="articleAbstract21">
1035					<div><p>Cutaneous protothecosis is a rare opportunistic infection caused by achlorophyllous algae of the <em>Prototheca</em> genus, presenting a diagnostic challenge due to its clinical polymorphism and lack of pathognomonic features.</p>
1036<p>We report a case of cutaneous protothecosis in a 78-year-old female patient with a long history of pruritic skin eruptions and uncontrolled long-term use of topical corticosteroids. During prior evaluation, systemic connective tissue disease and a paraneoplastic etiology of the cutaneous process were excluded. The definitive diagnostic step was a skin biopsy with histopathological examination, which revealed a lichenoid reaction along with productive dermal granulomatous inflammation, raising suspicion of an infectious origin of the dermatosis and prompting additional special stains. Ziehl–Neelsen staining was negative, and no acid-fast mycobacteria were identified. Periodic Acid–Schiff (PAS) staining revealed PAS-positive structures. Culturing of shave-biopsy material on Sabouraud dextrose agar yielded <em>Prototheca wickerhamii</em>, confirming the diagnosis of protothecosis. The patient was started on itraconazole, resulting in gradual regression of skin lesions and improvement of subjective symptoms.</p></div>
1037				</div>
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1056						<div class="pages"><b>Vestnik dermatologii i venerologii</b>. 2026;102(3):61-68</div>
1057		</div>
1058	</div>
1059	<div class="light issueArticlesViews">
1060		<div>
1061								<img src="/img/style/pages.png" alt="pages">
1062				<span>
1063					61-68
1064				</span>
1065						<img src="/img/style/views.png" alt="views">
1066			<span id="articleViews_16995">
1067				<img style='margin: auto;' src='/img/style/loadingSmall.gif'></td></tr></table>
1068				
1068<script>$("#articleViews_16995").load('https://vestnikdv.ru/jour/article/articleViews/16995');</script>
1068
1069			</span>
1070		</div>
1071	</div>
1072	<div class="light issueArticlesFiles">
1073										                					                					                									<div class="issueArticlesFilesBlock">
1074                                                                                                        <a href="https://vestnikdv.ru/jour/article/view/16995/2182" class="file">
1075                                                							<img src="/img/labels/pdf.png" alt="PDF"><br><span class="issueArticlesLabel">(Rus)</span>
1076													</a>
1077					</div>
1078					                                		<a href="https://vestnikdv.ru/jour/article/xml/16995" class="file" target="_blank"><img src="/img/labels/xml.png" alt="JATS&nbsp;XML">
1079			<br><span class="issueArticlesLabel">(JATS&nbsp;XML)</span>
1080		</a>
1081	</div>
1082		
1083					<div class="dark issueArticlesData">
1084		<h5 class="articleTitle">
1085			<a href="https://vestnikdv.ru/jour/article/view/16985">Experience of using a multi-component serum for hair loss in androgenetic alopecia in women</a>
1086		</h5>
1087		<div class="issueArticleInformation">
1088			<div class="articleCover">
1089							</div>
1090                        				<div class="authors">
1091					Gallyamova Y.A., Mareeva A.N.
1092				</div>
1093                        						<div class="abstract">
1094				<h6>Abstract</h6>
1095				<div class="articleAbstract" id="articleAbstract22">
1096					<div><p><strong>BACKGROUND: </strong>Androgenetic alopecia is a widespread disorder that presents therapeutic challenges due to patients' inflated expectations, low treatment compliance associated with inconvenient topical application, and concerns regarding adverse effects. Therefore, investigating the efficacy of non-drug multi-component agents for managing hair loss and stimulating hair growth appears highly relevant.</p>
1097<p><strong>AIM:</strong> Evaluation of the efficacy of a corrective and stimulating serum combining a minoxidil derivative and high-concentration niacinamide in women with androgenetic alopecia.</p>
1098<p><strong>METHODS: </strong>The study involved 38 female patients who applied the serum daily for 4 months. The outcomes were assessed clinically and using phototrichogram analysis.</p>
1099<p><strong>RESULTS: </strong>Upon completion of the treatment course, clinical recovery was observed in 25 patients (65.8%), significant improvement — in 4 (10.5%), and improvement — in 3 (7.9%). No effect was reported in 6 cases (15.8%). The proportion of telogen hair normalized (≤ 10%) in 27 women (71.1%).</p>
1100<p><strong>CONCLUSION: </strong>The multi-component serum applied in the study showed high efficacy and good tolerability in the treatment of female androgenetic alopecia. Its ease of use promotes better treatment compliance, allowing this product to be recommended for long-term application in the comprehensive management of this condition.</p></div>
1101				</div>
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1120						<div class="pages"><b>Vestnik dermatologii i venerologii</b>. 2026;102(3):69-76</div>
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1145	</div>
1146	<div class="heading"><h4>CLINICAL CASE REPORTS</h4></div>
1147		
1148					<div class="dark issueArticlesData">
1149		<h5 class="articleTitle">
1150			<a href="https://vestnikdv.ru/jour/article/view/16966">Scleromyxedema as a manifestation of monoclonal gammopathy of clinical significance</a>
1151		</h5>
1152		<div class="issueArticleInformation">
1153			<div class="articleCover">
1154							</div>
1155                        				<div class="authors">
1156					Chikin V.V., Soloveva M.V., Kovrigina A.M., Nefedova M.A.
1157				</div>
1158                        						<div class="abstract">
1159				<h6>Abstract</h6>
1160				<div class="articleAbstract" id="articleAbstract30">
1161					<div><p>The article describes a 57-year-old female patient with lesions on the scalp, trunk and extremities, who was diagnosed with scleromyxedema (myxedematous lichen) by a dermatovenereologist based on clinical data and histopathological examination of a skin specimen. An immunochemical study of serum proteins revealed an M-gradient in the g3 zone, formed by a Gk clone and amounting to 4.9 g/L. Immunophenotyping of blood cells revealed a population of clonal plasma cells with the CD138<sup>+</sup>CD38<sup>+</sup>CD56<sup>–</sup>CD10<sup>–</sup>CD117–kappa<sup>+</sup> immunophenotype (2.26% of all studied events).</p>
1162<p>Upon further examination by a hematologist, 2% of plasma cells were detected in the myelogram. Immunophenotyping of bone marrow cells by flow cytometry revealed 0.144% of plasma cells from all cells with the aberrant immunophenotype CD38dimCD138<sup>+</sup>CD319<sup>+</sup>CD19<sup>–</sup>CD45<sup>+</sup>/<sup>–</sup>CD56<sup>+</sup>/<sup>–</sup>CD27<sup>+</sup>/<sup>–</sup>CD117<sup>–</sup>/<sup>+</sup>CD200<sup>+</sup>CD20<sup>–</sup>/<sup>+</sup>. No criteria for symptomatic multiple myeloma or smoldering myeloma were found. The patient was diagnosed with monoclonal gammopathy of clinical significance, with predominant generalized skin involvement, associated with a monoclonal IgG secretion. VRD-based therapy (bortezomib, lenalidomide, dexamethasone) followed by autologous hematopoietic stem cell transplantation led to significant improvement. Gk secretion decreased to a trace, the bone marrow was sanitized, and a significant improvement in the patient’s skin condition was noted.</p>
1163<p>The presented case demonstrates the association of scleromyxedema with monoclonal gammopathy and indicates the need for patients with scleromyxedema to be examined by a hematologist.</p></div>
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1183						<div class="pages"><b>Vestnik dermatologii i venerologii</b>. 2026;102(3):77-91</div>
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1211		<h5 class="articleTitle">
1212			<a href="https://vestnikdv.ru/jour/article/view/16919">New therapeutic opportunities for linear porokeratosis</a>
1213		</h5>
1214		<div class="issueArticleInformation">
1215			<div class="articleCover">
1216							</div>
1217                        				<div class="authors">
1218					Ambarchian E.T., Belysheva T.S., Kletskaya I.S., Alekseeva A.D., Ivanchikov V.V.
1219				</div>
1220                        						<div class="abstract">
1221				<h6>Abstract</h6>
1222				<div class="articleAbstract" id="articleAbstract31">
1223					<div><p>Porokeratoses constitute a group of rare, clinically and genetically heterogeneous dermatoses characterized by abnormalities in epidermal keratinization due to pathogenic variants in genes involved in the mevalonate metabolic pathway. Treatment of porokeratosis has long been based on ablative procedures and various topical and systemic therapies, which have demonstrated very limited efficacy. The discovery of the metabolic pathway involved in the pathogenesis paved the way for a new class of topical agents, including a combination of statins and cholesterol, which demonstrate better results compared to previous treatment options.</p>
1224<p>We describe a case of a rare linear form of porokeratosis in an adolescent presenting with multiple brown maculopapular lesions measuring 1 to 8 mm in diameter and having a specific structure: mild central atrophy and areas of peripheral hyperkeratosis. The diagnosis was verified histologically and by identifying a pathogenic nucleotide sequence variant at the splice site of intron 1 within the <em>MVD</em> gene (c.70+5G>A). The disease therapy with a topical agent based on a combination of a statin and cholesterol was effective.</p>
1225<p>The described clinical case is of considerable value in the context of the differential diagnosis of linear skin lesions, as well as diseases accompanied by impaired keratinization.</p></div>
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1245						<div class="pages"><b>Vestnik dermatologii i venerologii</b>. 2026;102(3):92-98</div>
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